Published in Nature on October 30, 2003
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2008) 21.36
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2009) 12.51
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2010) 10.97
A translational profiling approach for the molecular characterization of CNS cell types. Cell (2008) 8.69
Genetic dissection of neural circuits. Neuron (2008) 7.97
Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell (2008) 7.74
A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex. Neuron (2011) 6.93
Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (2010) 5.48
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol (2011) 4.84
Modulation of striatal projection systems by dopamine. Annu Rev Neurosci (2011) 4.84
MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase. Immunity (2008) 4.59
Genetic dissection of an amygdala microcircuit that gates conditioned fear. Nature (2010) 4.34
Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling. Neuron (2011) 3.93
Striatal plasticity and basal ganglia circuit function. Neuron (2008) 3.89
Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature (2010) 3.70
Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens. Proc Natl Acad Sci U S A (2006) 3.68
High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression. PLoS One (2008) 3.44
Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster. Nat Methods (2009) 3.35
High-throughput in vivo analysis of gene expression in Caenorhabditis elegans. PLoS Biol (2007) 3.22
Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein. Neuron (2009) 3.15
Genetic identification of an On-Off direction-selective retinal ganglion cell subtype reveals a layer-specific subcortical map of posterior motion. Neuron (2009) 3.13
Serial two-photon tomography for automated ex vivo mouse brain imaging. Nat Methods (2012) 3.09
Dopaminergic neurons inhibit striatal output through non-canonical release of GABA. Nature (2012) 2.99
The functional organization of cutaneous low-threshold mechanosensory neurons. Cell (2011) 2.83
Biological substrates of reward and aversion: a nucleus accumbens activity hypothesis. Neuropharmacology (2008) 2.80
Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo. Neuron (2010) 2.75
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nat Neurosci (2013) 2.71
D2R striatopallidal neurons inhibit both locomotor and drug reward processes. Nat Neurosci (2009) 2.65
Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin. Nature (2013) 2.55
Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex. Cereb Cortex (2009) 2.51
PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord. Neuron (2006) 2.48
Adult mouse brain gene expression patterns bear an embryologic imprint. Proc Natl Acad Sci U S A (2005) 2.46
Reward processing by the opioid system in the brain. Physiol Rev (2009) 2.46
Dopaminergic modulation of synaptic transmission in cortex and striatum. Neuron (2012) 2.46
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat Neurosci (2015) 2.43
GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits. Neuron (2013) 2.43
Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens. Nat Neurosci (2010) 2.40
A high-resolution enhancer atlas of the developing telencephalon. Cell (2013) 2.34
Dichotomous anatomical properties of adult striatal medium spiny neurons. J Neurosci (2008) 2.29
Exploration and visualization of gene expression with neuroanatomy in the adult mouse brain. BMC Bioinformatics (2008) 2.27
SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons. Proc Natl Acad Sci U S A (2008) 2.26
Sox9 expression marks a subset of CD24-expressing small intestine epithelial stem cells that form organoids in vitro. Am J Physiol Gastrointest Liver Physiol (2010) 2.25
Molecular profiling of activated neurons by phosphorylated ribosome capture. Cell (2012) 2.22
Distinct SOX9 levels differentially mark stem/progenitor populations and enteroendocrine cells of the small intestine epithelium. Am J Physiol Gastrointest Liver Physiol (2009) 2.21
The cells and circuitry for itch responses in mice. Science (2013) 2.14
Neurotransmitter roles in synaptic modulation, plasticity and learning in the dorsal striatum. Neuropharmacology (2010) 2.14
Recurrent collateral connections of striatal medium spiny neurons are disrupted in models of Parkinson's disease. J Neurosci (2008) 2.10
A phosphatase cascade by which rewarding stimuli control nucleosomal response. Nature (2008) 2.10
Distinct molecular pathways for development of telencephalic interneuron subtypes revealed through analysis of Lhx6 mutants. J Comp Neurol (2008) 2.09
KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner. Neuron (2009) 2.08
Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain. Am J Hum Genet (2007) 2.08
Monosynaptic circuit tracing in vivo through Cre-dependent targeting and complementation of modified rabies virus. Proc Natl Acad Sci U S A (2010) 2.07
Spinal cholinergic interneurons regulate the excitability of motoneurons during locomotion. Proc Natl Acad Sci U S A (2007) 2.05
A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets. Genes Dev (2011) 2.04
Oxytocin enables maternal behaviour by balancing cortical inhibition. Nature (2015) 2.04
Genetic address book for retinal cell types. Nat Neurosci (2009) 2.02
The developmental integration of cortical interneurons into a functional network. Curr Top Dev Biol (2009) 2.01
Cortical connectivity and sensory coding. Nature (2013) 2.00
Psychiatry as a clinical neuroscience discipline. JAMA (2005) 2.00
Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex. Neuron (2011) 1.99
The corticostriatal pathway in Huntington's disease. Prog Neurobiol (2006) 1.99
Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo. Proc Natl Acad Sci U S A (2006) 1.95
MicroRNA-128 governs neuronal excitability and motor behavior in mice. Science (2013) 1.95
Monocyte chemoattractant protein-1 functions as a neuromodulator in dorsal root ganglia neurons. J Neurochem (2007) 1.93
Molecular neuroanatomy's "Three Gs": a primer. Neuron (2007) 1.91
Heterogeneity and diversity of striatal GABAergic interneurons. Front Neuroanat (2010) 1.89
The striatal balancing act in drug addiction: distinct roles of direct and indirect pathway medium spiny neurons. Front Neuroanat (2011) 1.87
A regulatory toolbox of MiniPromoters to drive selective expression in the brain. Proc Natl Acad Sci U S A (2010) 1.85
Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartments. Front Neuroanat (2011) 1.85
Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis. Elife (2014) 1.81
Neuroscience in the era of functional genomics and systems biology. Nature (2009) 1.80
A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev Biol (2008) 1.79
Differential excitability and modulation of striatal medium spiny neuron dendrites. J Neurosci (2008) 1.79
A digital atlas to characterize the mouse brain transcriptome. PLoS Comput Biol (2005) 1.78
Transgenic mice reveal unexpected diversity of on-off direction-selective retinal ganglion cell subtypes and brain structures involved in motion processing. J Neurosci (2011) 1.77
Laminar and columnar development of barrel cortex relies on thalamocortical neurotransmission. Neuron (2013) 1.74
Concepts and methods for the study of axonal regeneration in the CNS. Neuron (2012) 1.74
MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival. J Exp Med (2007) 1.74
Experience-dependent structural plasticity in the cortex. Trends Neurosci (2011) 1.73
Relevance of BAC transgene copy number in mice: transgene copy number variation across multiple transgenic lines and correlations with transgene integrity and expression. Mamm Genome (2007) 1.71
An embedded subnetwork of highly active neurons in the neocortex. Neuron (2010) 1.70
A nanobody-based system using fluorescent proteins as scaffolds for cell-specific gene manipulation. Cell (2013) 1.69
A silent synapse-based mechanism for cocaine-induced locomotor sensitization. J Neurosci (2011) 1.68
DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Hum Mol Genet (2009) 1.68
Calcium signaling cascade links dopamine D1-D2 receptor heteromer to striatal BDNF production and neuronal growth. Proc Natl Acad Sci U S A (2009) 1.67
Cadherin-6 mediates axon-target matching in a non-image-forming visual circuit. Neuron (2011) 1.67
TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract. Proc Natl Acad Sci U S A (2011) 1.67
Pacemaking in dopaminergic ventral tegmental area neurons: depolarizing drive from background and voltage-dependent sodium conductances. J Neurosci (2010) 1.66
Bmp2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoter. Mol Cell Biol (2007) 1.66
CRH Engagement of the Locus Coeruleus Noradrenergic System Mediates Stress-Induced Anxiety. Neuron (2015) 1.64
Patterning of frontal cortex subdivisions by Fgf17. Proc Natl Acad Sci U S A (2007) 1.63
Genetically-directed, cell type-specific sparse labeling for the analysis of neuronal morphology. PLoS One (2008) 1.63
Visualizing circuits and systems using transgenic reporters of neural activity. Curr Opin Neurobiol (2007) 1.63
Proopiomelanocortin expression in both GABA and glutamate neurons. J Neurosci (2009) 1.62
Striatal medium-sized spiny neurons: identification by nuclear staining and study of neuronal subpopulations in BAC transgenic mice. PLoS One (2009) 1.61
Schlemm's canal is a unique vessel with a combination of blood vascular and lymphatic phenotypes that forms by a novel developmental process. PLoS Biol (2014) 1.61
Visualization of lymphatic vessels by Prox1-promoter directed GFP reporter in a bacterial artificial chromosome-based transgenic mouse. Blood (2010) 1.61
All-you-can-eat: autophagy in neurodegeneration and neuroprotection. Mol Neurodegener (2009) 1.60
Developmental origin of preBötzinger complex respiratory neurons. J Neurosci (2010) 1.60
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science (2009) 18.82
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A (2003) 15.59
A translational profiling approach for the molecular characterization of CNS cell types. Cell (2008) 8.69
The knockout mouse project. Nat Genet (2004) 7.80
Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell (2008) 7.74
Recurrent 16p11.2 microdeletions in autism. Hum Mol Genet (2007) 6.75
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol (2009) 6.69
Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. J Neurosci (2007) 5.87
Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature (2010) 5.11
MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell (2012) 4.56
A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice. Neuron (2002) 4.27
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol (2005) 3.89
Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication. Genome Res (2002) 3.61
Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron (2004) 3.58
Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proc Natl Acad Sci U S A (2002) 3.34
Induction of autophagy in axonal dystrophy and degeneration. J Neurosci (2006) 3.28
Autophagy and its possible roles in nervous system diseases, damage and repair. Autophagy (2005) 3.27
Odorant receptor expression defines functional units in the mouse olfactory system. J Neurosci (2002) 3.18
Par6alpha signaling controls glial-guided neuronal migration. Nat Neurosci (2004) 3.06
The functional organization of cutaneous low-threshold mechanosensory neurons. Cell (2011) 2.83
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metab (2012) 2.80
In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors. Neuron (2008) 2.69
Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Hum Mol Genet (2004) 2.63
Novel submicroscopic chromosomal abnormalities detected in autism spectrum disorder. Biol Psychiatry (2008) 2.60
Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01. Clin Cancer Res (2005) 2.46
Role of Unc51.1 and its binding partners in CNS axon outgrowth. Genes Dev (2004) 2.34
The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation. Genes Dev (2005) 2.14
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron (2005) 2.11
To beat or not to beat: roles of cilia in development and disease. Hum Mol Genet (2003) 2.11
Lynx1, a cholinergic brake, limits plasticity in adult visual cortex. Science (2010) 2.11
Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice. Autism Res (2008) 2.08
Genetic address book for retinal cell types. Nat Neurosci (2009) 2.02
Myosin II motors and F-actin dynamics drive the coordinated movement of the centrosome and soma during CNS glial-guided neuronal migration. Neuron (2009) 1.94
Gli1 is important for medulloblastoma formation in Ptc1+/- mice. Oncogene (2005) 1.92
Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells. Genes Dev (2005) 1.81
Mapping segmental and sequence variations among laboratory mice using BAC array CGH. Genome Res (2005) 1.71
Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus. Hum Mol Genet (2002) 1.69
Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors. Cancer Res (2003) 1.67
Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs. Nat Neurosci (2008) 1.63
20q11.1 amplification in giant-cell tumor of bone: Array CGH, FISH, and association with outcome. Genes Chromosomes Cancer (2006) 1.56
Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1. Neuron (2002) 1.56
Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. Development (2010) 1.55
Mice that lack astrotactin have slowed neuronal migration. Development (2002) 1.53
Cell-type specific properties of pyramidal neurons in neocortex underlying a layout that is modifiable depending on the cortical area. Cereb Cortex (2009) 1.51
Development and characterization of a novel human Waldenström macroglobulinemia cell line: RPCI-WM1, Roswell Park Cancer Institute - Waldenström Macroglobulinemia 1. Leuk Lymphoma (2012) 1.50
Neuronal polarity in CNS development. Genes Dev (2006) 1.49
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. J Neurosci (2008) 1.48
Molecular markers of neuronal progenitors in the embryonic cerebellar anlage. J Neurosci (2006) 1.47
The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron (2006) 1.46
A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions. Hum Mol Genet (2010) 1.42
Identification of the cortical neurons that mediate antidepressant responses. Cell (2012) 1.42
Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells. Nucleic Acids Res (2010) 1.41
Cerebellum development and medulloblastoma. Curr Top Dev Biol (2011) 1.40
Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo. Neuron (2004) 1.39
Analytical and clinical validity of whole-genome oligonucleotide array comparative genomic hybridization for pediatric patients with mental retardation and developmental delay. Am J Med Genet A (2008) 1.39
Astn2, a novel member of the astrotactin gene family, regulates the trafficking of ASTN1 during glial-guided neuronal migration. J Neurosci (2010) 1.35
Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proc Natl Acad Sci U S A (2012) 1.33
Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis. Nat Protoc (2010) 1.33
The role of Rho GTPase proteins in CNS neuronal migration. Dev Neurobiol (2011) 1.28
Differentiation of ES cells into cerebellar neurons. Proc Natl Acad Sci U S A (2007) 1.27
Defining the expression pattern of the LGI1 gene in BAC transgenic mice. Mamm Genome (2007) 1.25
Distribution of Kv3.3 potassium channel subunits in distinct neuronal populations of mouse brain. J Comp Neurol (2007) 1.24
Using binary surfactant mixtures to simultaneously improve the dimensional tunability and monodispersity in the seeded growth of gold nanorods. Nano Lett (2013) 1.24
Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme. Cancer Genet Cytogenet (2004) 1.24
A role for LYNX2 in anxiety-related behavior. Proc Natl Acad Sci U S A (2009) 1.23
Gab2-mediated signaling promotes melanoma metastasis. Am J Pathol (2009) 1.21
Molecular characterization of the t(3;9) associated with immortalization in the MCF10A cell line. Cancer Genet Cytogenet (2005) 1.20
The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects. J Comp Neurol (2007) 1.19
Novel amplicons on the short arm of chromosome 7 identified using high resolution array CGH contain over expressed genes in addition to EGFR in glioblastoma multiforme. Genes Chromosomes Cancer (2005) 1.19
Modified bacterial artificial chromosomes for zebrafish transgenesis. Methods (2006) 1.16
Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol. J Biol Chem (2007) 1.15
Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation. Genes Dev (2013) 1.15
Two functional coding single nucleotide polymorphisms in STK15 (Aurora-A) coordinately increase esophageal cancer risk. Cancer Res (2005) 1.15
Familial 4.3 Mb duplication of 21q22 sheds new light on the Down syndrome critical region. J Med Genet (2007) 1.14
Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord. Development (2012) 1.13
Role of alcohol metabolism in non-alcoholic steatohepatitis. PLoS One (2010) 1.13
Improved size-tunable synthesis of monodisperse gold nanorods through the use of aromatic additives. ACS Nano (2012) 1.11
The neuron identity problem: form meets function. Neuron (2013) 1.11
Genetic lineage tracing defines distinct neurogenic and gliogenic stages of ventral telencephalic radial glial development. Neural Dev (2008) 1.11
Proteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapse. PLoS Biol (2009) 1.11
Genomic profiling of myeloid sarcoma by array comparative genomic hybridization. Genes Chromosomes Cancer (2005) 1.10
Strain-dependent differences in the efficiency of transgenic mouse production. Transgenic Res (2003) 1.09
Upregulation of hemoglobin expression by oxidative stress in hepatocytes and its implication in nonalcoholic steatohepatitis. PLoS One (2011) 1.08
Large-scale genomic approaches to brain development and circuitry. Annu Rev Neurosci (2005) 1.08
Strain-specific regulation of striatal phenotype in Drd2-eGFP BAC transgenic mice. J Neurosci (2012) 1.07
BAC transgenic mice and the GENSAT database of engineered mouse strains. Cold Spring Harb Protoc (2013) 1.05
The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors. J Neurosci (2013) 1.05
In vitro and in vivo irinotecan-induced changes in expression profiles of cell cycle and apoptosis-associated genes in acute myeloid leukemia cells. Mol Cancer Ther (2005) 1.02
Histone deacetylase inhibitors SAHA and sodium butyrate block G1-to-S cell cycle progression in neurosphere formation by adult subventricular cells. BMC Neurosci (2011) 1.00
High-resolution analysis of genetic events in cancer cells using bacterial artificial chromosome arrays and comparative genome hybridization. Adv Cancer Res (2003) 0.99
Gene-resolution analysis of DNA copy number variation using oligonucleotide expression microarrays. BMC Genomics (2007) 0.98
Characterization of the A2AR-D2R interface: focus on the role of the C-terminal tail and the transmembrane helices. Biochem Biophys Res Commun (2010) 0.98
Molecular karyotypes of Hodgkin and Reed-Sternberg cells at disease onset reveal distinct copy number alterations in chemosensitive versus refractory Hodgkin lymphoma. Clin Cancer Res (2011) 0.97
Array CGH analysis of pediatric medulloblastomas. Genes Chromosomes Cancer (2006) 0.97
Downregulation of microRNA-214 and overexpression of FGFR-1 contribute to hepatocellular carcinoma metastasis. Biochem Biophys Res Commun (2013) 0.97
Genetic analysis of Down syndrome-associated heart defects in mice. Hum Genet (2011) 0.97
A de novo 1p34.2 microdeletion identifies the synaptic vesicle gene RIMS3 as a novel candidate for autism. J Med Genet (2009) 0.96