Published in Nat Cell Biol on March 01, 2002
Convergence of Wnt, beta-catenin, and cadherin pathways. Science (2004) 13.13
Cadherins and cancer: how does cadherin dysfunction promote tumor progression? Oncogene (2008) 3.63
The Wnt signaling pathway and its role in tumor development. J Cancer Res Clin Oncol (2003) 3.06
Wnt signaling from development to disease: insights from model systems. Cold Spring Harb Perspect Biol (2009) 2.42
Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes. J Cell Biol (2004) 2.33
Remodeling epithelial cell organization: transitions between front-rear and apical-basal polarity. Cold Spring Harb Perspect Biol (2009) 2.01
Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila. Dev Cell (2009) 1.95
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation. Proc Natl Acad Sci U S A (2002) 1.94
Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains. Genes Dev (2008) 1.74
Identifying spatially similar gene expression patterns in early stage fruit fly embryo images: binary feature versus invariant moment digital representations. BMC Bioinformatics (2004) 1.64
Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia. Med Mol Morphol (2007) 1.20
Polarity in stem cell division: asymmetric stem cell division in tissue homeostasis. Cold Spring Harb Perspect Biol (2010) 1.17
Adenomatous polyposis coli plays a key role, in vivo, in coordinating assembly of the neuronal nicotinic postsynaptic complex. Mol Cell Neurosci (2008) 1.02
Adenomatous polyposis coli regulates endothelial cell migration independent of roles in beta-catenin signaling and cell-cell adhesion. Mol Biol Cell (2010) 1.01
Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development. Dev Biol (2007) 1.00
The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled. Open Biol (2011) 1.00
Mechanism of adenomatous polyposis coli (APC)-mediated blockage of long-patch base excision repair. Biochemistry (2006) 0.97
Examination of actin and microtubule dependent APC localisations in living mammalian cells. BMC Cell Biol (2006) 0.94
PP2A and GSK-3beta act antagonistically to regulate active zone development. J Neurosci (2009) 0.94
Adenomatous polyposis coli (APC) is essential for maintaining the integrity of the seminiferous epithelium. Mol Endocrinol (2011) 0.87
Centrosome misorientation mediates slowing of the cell cycle under limited nutrient conditions in Drosophila male germline stem cells. Mol Biol Cell (2012) 0.87
Brain tumor specifies intermediate progenitor cell identity by attenuating β-catenin/Armadillo activity. Development (2013) 0.87
Amer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterning. J Biol Chem (2011) 0.84
Intracellular shuttling of a Drosophila APC tumour suppressor homolog. BMC Cell Biol (2004) 0.82
What can humans learn from flies about adenomatous polyposis coli? Bioessays (2002) 0.80
Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners. Cell Discov (2015) 0.75
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science (2007) 5.45
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization. Nat Struct Mol Biol (2007) 3.13
Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function. Nat Cell Biol (2004) 2.90
Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations. N Engl J Med (2015) 2.87
A new nuclear component of the Wnt signalling pathway. Nat Cell Biol (2002) 2.23
A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling. Curr Biol (2003) 2.17
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex. Mol Cell (2008) 2.09
The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles. J Cell Sci (2005) 2.05
Dynamic recruitment of axin by Dishevelled protein assemblies. J Cell Sci (2007) 1.87
Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription. EMBO J (2003) 1.75
Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains. Genes Dev (2008) 1.74
Bre1 is required for Notch signaling and histone modification. Dev Cell (2005) 1.58
An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains. Nat Struct Mol Biol (2011) 1.55
Wingless-independent association of Pygopus with dTCF target genes. Curr Biol (2007) 1.40
The APC tumor suppressor binds to C-terminal binding protein to divert nuclear beta-catenin from TCF. Dev Cell (2004) 1.37
Inhibition of GSK3 by Wnt signalling--two contrasting models. J Cell Sci (2011) 1.33
Stability elements in the LRP6 cytoplasmic tail confer efficient signalling upon DIX-dependent polymerization. J Cell Sci (2010) 1.29
The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells. BMC Cancer (2008) 1.26
Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin. Proc Natl Acad Sci U S A (2011) 1.24
Pygopus residues required for its binding to Legless are critical for transcription and development. J Biol Chem (2003) 1.15
An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid. Nat Commun (2012) 1.11
A role of Pygopus as an anti-repressor in facilitating Wnt-dependent transcription. Proc Natl Acad Sci U S A (2008) 1.11
LEF1 and B9L shield β-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors. Cancer Res (2014) 1.08
Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer. Cancer Res (2010) 1.07
The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled. Open Biol (2011) 1.00
Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists. BMC Cancer (2014) 0.98
Loss of Drosophila borealin causes polyploidy, delayed apoptosis and abnormal tissue development. Development (2005) 0.91
Competitive binding of a benzimidazole to the histone-binding pocket of the Pygo PHD finger. ACS Chem Biol (2014) 0.87
The transcriptional repressor Brinker antagonizes Wingless signaling. Genes Dev (2002) 0.87
Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor. J Mol Biol (2010) 0.86
Intracellular shuttling of a Drosophila APC tumour suppressor homolog. BMC Cell Biol (2004) 0.82
Evolutionary adaptation of the fly Pygo PHD finger toward recognizing histone H3 tail methylated at arginine 2. Structure (2013) 0.78
Correction: Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9. Elife (2017) 0.75