Published in Cold Spring Harb Perspect Biol on August 01, 2009
WNT signaling in bone homeostasis and disease: from human mutations to treatments. Nat Med (2013) 4.52
Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling. Cold Spring Harb Perspect Biol (2010) 3.02
TCF/LEFs and Wnt signaling in the nucleus. Cold Spring Harb Perspect Biol (2012) 1.78
MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. Proc Natl Acad Sci U S A (2015) 1.68
Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development. J Bone Miner Res (2013) 1.64
Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2014) 1.61
Adhesive and signaling functions of cadherins and catenins in vertebrate development. Cold Spring Harb Perspect Biol (2009) 1.52
LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling. Mol Cell Biol (2012) 1.48
Wnt/beta-catenin signaling and small molecule inhibitors. Curr Pharm Des (2013) 1.44
Cutaneous wound healing: recruiting developmental pathways for regeneration. Cell Mol Life Sci (2012) 1.40
Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures. Nat Med (2014) 1.39
Discovering the molecular components of intercellular junctions--a historical view. Cold Spring Harb Perspect Biol (2009) 1.39
The way Wnt works: components and mechanism. Growth Factors (2012) 1.37
Wnt signaling. Cold Spring Harb Perspect Biol (2012) 1.34
The secret life of α-catenin: moonlighting in morphogenesis. J Cell Biol (2011) 1.34
Cellular signaling and biological functions of R-spondins. Cell Signal (2011) 1.25
Planar cell polarity: keeping hairs straight is not so simple. Cold Spring Harb Perspect Biol (2010) 1.24
The catenin family at a glance. J Cell Sci (2010) 1.24
Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling. Mol Biol Cell (2011) 1.21
Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse. PLoS One (2012) 1.14
The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis. EMBO Mol Med (2011) 1.10
Junctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity. Cold Spring Harb Perspect Biol (2009) 1.09
Looking beyond the Wnt pathway for the deep nature of β-catenin. EMBO Rep (2013) 1.06
Wnt signaling in neuromuscular junction development. Cold Spring Harb Perspect Biol (2012) 1.05
The oligomeric state of CtBP determines its role as a transcriptional co-activator and co-repressor of Wingless targets. EMBO J (2011) 1.02
Beta-catenin--a supporting role in the skeleton. J Cell Biochem (2010) 0.99
Roles of N-glycosylation and lipidation in Wg secretion and signaling. Dev Biol (2012) 0.96
Fibronectin and beta-catenin act in a regulatory loop in dermal fibroblasts to modulate cutaneous healing. J Biol Chem (2011) 0.95
Normal and abnormal epithelial differentiation in the female reproductive tract. Differentiation (2011) 0.95
Differential palmit(e)oylation of Wnt1 on C93 and S224 residues has overlapping and distinct consequences. PLoS One (2011) 0.94
Retracted Specific armadillo repeat sequences facilitate β-catenin nuclear transport in live cells via direct binding to nucleoporins Nup62, Nup153, and RanBP2/Nup358. J Biol Chem (2011) 0.94
Asymmetrically expressed axin required for anterior development in Tribolium. Proc Natl Acad Sci U S A (2012) 0.94
Development of small molecules targeting the Wnt pathway for the treatment of colon cancer: a high-throughput screening approach. Am J Physiol Gastrointest Liver Physiol (2010) 0.93
Presenilin deficiency or lysosomal inhibition enhances Wnt signaling through relocalization of GSK3 to the late-endosomal compartment. Cell Rep (2012) 0.92
Regulation of Wnt signaling by the tumor suppressor adenomatous polyposis coli does not require the ability to enter the nucleus or a particular cytoplasmic localization. Mol Biol Cell (2012) 0.92
Emergent complexity of the cytoskeleton: from single filaments to tissue. Adv Phys (2013) 0.92
Regulation of developmental intercellular signalling by intracellular trafficking. EMBO J (2011) 0.91
β-catenin-dependent Wnt signaling in C. elegans: teaching an old dog a new trick. Cold Spring Harb Perspect Biol (2012) 0.91
Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation. Mol Cell Biol (2011) 0.91
How to design a genetic mating scheme: a basic training package for Drosophila genetics. G3 (Bethesda) (2013) 0.90
A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins. Sci Signal (2012) 0.90
Testing models of the APC tumor suppressor/β-catenin interaction reshapes our view of the destruction complex in Wnt signaling. Genetics (2014) 0.89
Signaling from the adherens junction. Subcell Biochem (2012) 0.89
Growth factor- and cytokine-driven pathways governing liver stemness and differentiation. World J Gastroenterol (2010) 0.88
Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche. Development (2015) 0.88
Epigenetics and autosomal dominant polycystic kidney disease. Biochim Biophys Acta (2010) 0.88
Distinct DNA binding sites contribute to the TCF transcriptional switch in C. elegans and Drosophila. PLoS Genet (2014) 0.87
Wnt activation by wild type and mutant myocilin in cultured human trabecular meshwork cells. PLoS One (2012) 0.86
Structure-function analysis of the C-clamp of TCF/Pangolin in Wnt/ß-catenin signaling. PLoS One (2014) 0.86
Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates RhoA activity and epithelial integrity. J Cell Sci (2010) 0.86
Cadherins as targets for genetic diseases. Cold Spring Harb Perspect Biol (2010) 0.85
hSETD1A regulates Wnt target genes and controls tumor growth of colorectal cancer cells. Cancer Res (2013) 0.85
Wnt-mediated repression via bipartite DNA recognition by TCF in the Drosophila hematopoietic system. PLoS Genet (2014) 0.85
Wnt secretion and gradient formation. Int J Mol Sci (2013) 0.84
Keeping Wnt signalosome in check by vesicular traffic. J Cell Physiol (2015) 0.84
Inhibition of Tcf-4 induces apoptosis and enhances chemosensitivity of colon cancer cells. PLoS One (2012) 0.84
Destruction complex function in the Wnt signaling pathway of Drosophila requires multiple interactions between Adenomatous polyposis coli 2 and Armadillo. Genetics (2011) 0.84
Self-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex. Mol Biol Cell (2014) 0.84
Modeling Wnt/β-Catenin Target Gene Expression in APC and Wnt Gradients Under Wild Type and Mutant Conditions. Front Physiol (2013) 0.83
Inhibition by chondroitin sulfate E can specify functional Wnt/β-catenin signaling thresholds in NIH3T3 fibroblasts. J Biol Chem (2012) 0.83
Drosophila homeodomain-interacting protein kinase inhibits the Skp1-Cul1-F-box E3 ligase complex to dually promote Wingless and Hedgehog signaling. Proc Natl Acad Sci U S A (2011) 0.83
Identification of the WNT1 residues required for palmitoylation by Porcupine. FEBS Lett (2014) 0.83
Construction and Experimental Validation of a Petri Net Model of Wnt/β-Catenin Signaling. PLoS One (2016) 0.82
Inhibition of Wnt/β-catenin signaling by a soluble collagen-derived frizzled domain interacting with Wnt3a and the receptors frizzled 1 and 8. PLoS One (2012) 0.82
Defining components of the ß-catenin destruction complex and exploring its regulation and mechanisms of action during development. PLoS One (2012) 0.82
Analysis of Wnt signaling β-catenin spatial dynamics in HEK293T cells. BMC Syst Biol (2014) 0.81
ARF6-regulated endocytosis of growth factor receptors links cadherin-based adhesion to canonical Wnt signaling in epithelia. Mol Cell Biol (2013) 0.81
The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma. Sci Rep (2016) 0.81
Use of an activated beta-catenin to identify Wnt pathway target genes in caenorhabditis elegans, including a subset of collagen genes expressed in late larval development. G3 (Bethesda) (2014) 0.81
Regulation of subcellular distribution and oncogenic potential of nucleophosmin by plakoglobin. Oncogenesis (2012) 0.81
Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling. PLoS One (2014) 0.81
Neural crest specification by noncanonical Wnt signaling and PAR-1. Development (2011) 0.81
Prom1 function in development, intestinal inflammation, and intestinal tumorigenesis. Front Oncol (2014) 0.81
Extrinsic Regulation of Satellite Cell Function and Muscle Regeneration Capacity during Aging. J Stem Cell Res Ther (2012) 0.80
Canonical WNT signaling enhances stem cell expression in the developing heart without a corresponding inhibition of cardiogenic differentiation. Stem Cells Dev (2011) 0.80
Dishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signaling. J Mol Signal (2010) 0.80
ABCD2 is a direct target of β-catenin and TCF-4: implications for X-linked adrenoleukodystrophy therapy. PLoS One (2013) 0.80
Osteoblast-Specific Overexpression of Human WNT16 Increases Both Cortical and Trabecular Bone Mass and Structure in Mice. Endocrinology (2015) 0.79
Generation and characterization of monoclonal antibodies against human Chibby protein. Hybridoma (Larchmt) (2011) 0.79
Discovering pathway cross-talks based on functional relations between pathways. BMC Genomics (2012) 0.79
Chibby suppresses growth of human SW480 colon adenocarcinoma cells through inhibition of β-catenin signaling. J Mol Signal (2012) 0.79
The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2. J Biol Chem (2016) 0.78
LGR5 promotes the proliferation of colorectal cancer cells via the Wnt/β-catenin signaling pathway. Oncol Lett (2015) 0.78
WNT protein-independent constitutive nuclear localization of beta-catenin protein and its low degradation rate in thalamic neurons. J Biol Chem (2011) 0.78
Differential expression of Wnt signaling molecules between pre- and postmenopausal endometrial epithelial cells suggests a population of putative epithelial stem/progenitor cells reside in the basalis layer. Endocrinology (2012) 0.78
Prostaglandin E2 promotes the nuclear accumulation of lymphoid enhancer factor-1 in poorly differentiated breast cancer cells. Prostaglandins Other Lipid Mediat (2012) 0.77
Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease. Kidney Int (2016) 0.77
Curcumin Nanoformulation for Cervical Cancer Treatment. Sci Rep (2016) 0.77
Proteomic analysis reveals APC-dependent post-translational modifications and identifies a novel regulator of β-catenin. Development (2016) 0.77
The Role of the C-Clamp in Wnt-Related Colorectal Cancers. Cancers (Basel) (2016) 0.77
Inhibition of heart formation by lithium is an indirect result of the disruption of tissue organization within the embryo. Dev Growth Differ (2011) 0.76
Identification of Wnt Pathway Target Genes Regulating the Division and Differentiation of Larval Seam Cells and Vulval Precursor Cells in Caenorhabditis elegans. G3 (Bethesda) (2015) 0.76
Evidence for the Nucleo-Apical Shuttling of a Beta-Catenin Like Plasmodium falciparum Armadillo Repeat Containing Protein. PLoS One (2016) 0.76
Concentration-dependent effects of WNTLESS on WNT1/3A signaling. Dev Dyn (2014) 0.76
Roles of Wnt pathway genes wls, wnt9a, wnt5b, frzb and gpc4 in regulating convergent-extension during zebrafish palate morphogenesis. Development (2016) 0.76
Receptor endocytosis: Frizzled joins the ubiquitin club. EMBO J (2010) 0.76
Non-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer Cells. PLoS One (2015) 0.75
Oxygen levels and the regulation of cell adhesion in the nervous system: a control point for morphogenesis in development, disease and evolution? Cell Adh Migr (2012) 0.75
The two SAMP repeats and their phosphorylation state in Drosophila Adenomatous polyposis coli-2 play mechanistically distinct roles in negatively regulating Wnt signaling. Mol Biol Cell (2015) 0.75
Wnt/beta-catenin signaling in development and disease. Cell (2006) 30.09
Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature (2003) 12.54
Association of the APC gene product with beta-catenin. Science (1993) 8.20
A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev Cell (2003) 7.93
Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc Natl Acad Sci U S A (1995) 7.31
Association of the APC tumor suppressor protein with catenins. Science (1993) 7.17
Heterochromatin and epigenetic control of gene expression. Science (2003) 7.12
LDL-receptor-related proteins in Wnt signal transduction. Nature (2000) 6.94
Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science (2003) 6.72
Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity. Cell (2006) 6.49
Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem (2006) 6.32
The many ways of Wnt in cancer. Curr Opin Genet Dev (2007) 6.29
LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development (2004) 6.21
The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell (1997) 6.10
A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. Science (1991) 5.71
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature (2005) 5.50
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science (2007) 5.45
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell (2001) 5.19
The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors. Nature (1998) 5.16
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling. Science (2007) 5.08
Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion. Dev Cell (2006) 4.89
Links between signal transduction, transcription and adhesion in epithelial bud development. Nature (2003) 4.88
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature (2005) 4.88
Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev (2004) 4.78
Functional interaction between beta-catenin and FOXO in oxidative stress signaling. Science (2005) 4.61
The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration. J Cell Biol (1996) 4.56
A repeating amino acid motif shared by proteins with diverse cellular roles. Cell (1994) 4.56
Drosophila Tcf and Groucho interact to repress Wingless signalling activity. Nature (1998) 4.50
Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases. Cell (2002) 4.38
Lipoprotein particles are required for Hedgehog and Wingless signalling. Nature (2005) 4.38
A mechanism for Wnt coreceptor activation. Mol Cell (2004) 4.31
Wnt signaling: is the party in the nucleus? Genes Dev (2006) 4.10
Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell (2006) 4.09
An X chromosome gene, WTX, is commonly inactivated in Wilms tumor. Science (2007) 4.00
The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes. Genes Dev (2006) 3.85
The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. Cell (1987) 3.78
The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates. EMBO J (2000) 3.77
Direct and long-range action of a wingless morphogen gradient. Cell (1996) 3.73
LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic. Cell (1997) 3.63
The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell (1990) 3.57
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development (2005) 3.51
Wnt and calcium signaling: beta-catenin-independent pathways. Cell Calcium (2005) 3.46
beta-catenin destruction complex: insights and questions from a structural perspective. Oncogene (2006) 3.43
Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Cell (2002) 3.42
Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation. Nat Struct Mol Biol (2005) 3.41
Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell (2002) 3.37
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development (2007) 3.28
Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. Am J Hum Genet (2004) 3.21
The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression. J Cell Biol (2000) 3.13
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization. Nat Struct Mol Biol (2007) 3.13
Wnt signaling: complexity at the surface. J Cell Sci (2006) 3.11
Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Mol Cell (2003) 3.06
Wnt signaling requires retromer-dependent recycling of MIG-14/Wntless in Wnt-producing cells. Dev Cell (2007) 3.02
Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling. Cold Spring Harb Perspect Biol (2010) 3.02
Recycle your receptors with retromer. Trends Cell Biol (2005) 3.02
The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network. Dev Cell (2007) 3.00
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions. Genes Dev (2004) 2.99
Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity. Dev Cell (2003) 2.95
Crystal structure of a beta-catenin/Tcf complex. Cell (2000) 2.93
Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function. Nat Cell Biol (2004) 2.90
Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction. Dev Biol (2003) 2.86
Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP. Development (2004) 2.84
Diversity of LEF/TCF action in development and disease. Oncogene (2006) 2.84
The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade. Hum Mol Genet (2002) 2.69
The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties. J Cell Biol (1992) 2.69
Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein. Genes Dev (2000) 2.65
Patterning mechanisms controlling vertebrate limb development. Annu Rev Cell Dev Biol (2001) 2.64
The role of Axin2 in calvarial morphogenesis and craniosynostosis. Development (2005) 2.63
Alternative wnt signaling is initiated by distinct receptors. Sci Signal (2008) 2.52
Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin. Dev Cell (2006) 2.49
Ancestry and diversity of the HMG box superfamily. Nucleic Acids Res (1993) 2.47
Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo. Cell (2006) 2.47
Wingless secretion promotes and requires retromer-dependent cycling of Wntless. Nat Cell Biol (2008) 2.43
Phosphatidylinositol phosphate kinases put PI4,5P(2) in its place. J Membr Biol (2003) 2.43
Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway. Nature (2003) 2.42
Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex. Nat Cell Biol (2008) 2.38
naked cuticle encodes an inducible antagonist of Wnt signalling. Nature (2000) 2.35
Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes. Development (2004) 2.33
dishevelled and armadillo act in the wingless signalling pathway in Drosophila. Nature (1994) 2.29
A new nuclear component of the Wnt signalling pathway. Nat Cell Biol (2002) 2.23
Mutations in the APC gene and their implications for protein structure and function. Curr Opin Genet Dev (1995) 2.22
Naked cuticle targets dishevelled to antagonize Wnt signal transduction. Genes Dev (2001) 2.16
SnapShot: Noncanonical Wnt Signaling Pathways. Cell (2007) 2.14
LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin. Proc Natl Acad Sci U S A (2008) 2.14
Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation. Mol Cell (2004) 2.13
TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis. Nat Cell Biol (2008) 2.12
Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. EMBO J (1993) 2.12
Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila. Development (2002) 2.11
Transcription under the control of nuclear Arm/beta-catenin. Curr Biol (2006) 2.11
C. elegans AP-2 and retromer control Wnt signaling by regulating mig-14/Wntless. Dev Cell (2007) 2.10
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex. Mol Cell (2008) 2.09
Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis. J Cell Biol (1999) 2.04
Thermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinity. J Biol Chem (2005) 2.04
HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient. Dev Cell (2002) 2.03
Trimeric G protein-dependent frizzled signaling in Drosophila. Cell (2005) 2.03
C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila. EMBO J (2006) 2.01
Scaffolding microdomains and beyond: the function of reggie/flotillin proteins. Cell Mol Life Sci (2005) 2.01
Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface. Development (2003) 1.98
Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. Genes Dev (2007) 1.98
Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling. Biochem J (2007) 1.95
Noninvasive imaging beyond the diffraction limit of 3D dynamics in thickly fluorescent specimens. Cell (2012) 2.72
The SCF Slimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication. J Cell Biol (2009) 2.43
The positioning and segregation of apical cues during epithelial polarity establishment in Drosophila. J Cell Biol (2005) 2.41
A role for a novel centrosome cycle in asymmetric cell division. J Cell Biol (2007) 2.40
Can 1000 reviews be wrong? Actin, alpha-Catenin, and adherens junctions. Cell (2005) 2.01
The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction. J Cell Biol (2009) 1.90
Adherens junction-dependent and -independent steps in the establishment of epithelial cell polarity in Drosophila. J Cell Biol (2004) 1.86
Enabled plays key roles in embryonic epithelial morphogenesis in Drosophila. Development (2007) 1.76
Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila. Development (2007) 1.70
Decisions, decisions: beta-catenin chooses between adhesion and transcription. Trends Cell Biol (2005) 1.66
Puckered, a Drosophila MAPK phosphatase, ensures cell viability by antagonizing JNK-induced apoptosis. Development (2005) 1.65
A multicomponent assembly pathway contributes to the formation of acentrosomal microtubule arrays in interphase Drosophila cells. Mol Biol Cell (2008) 1.64
Drosophila p120catenin plays a supporting role in cell adhesion but is not an essential adherens junction component. J Cell Biol (2003) 1.57
Balancing different types of actin polymerization at distinct sites: roles for Abelson kinase and Enabled. J Cell Biol (2003) 1.56
Cytoskeletal dynamics and cell signaling during planar polarity establishment in the Drosophila embryonic denticle. J Cell Sci (2006) 1.47
Diaphanous regulates myosin and adherens junctions to control cell contractility and protrusive behavior during morphogenesis. Development (2008) 1.45
Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila. Development (2006) 1.37
aPKC controls microtubule organization to balance adherens junction symmetry and planar polarity during development. Dev Cell (2007) 1.30
Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations. Dev Biol (2002) 1.28
Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs. Dev Biol (2002) 1.27
A contractile actomyosin network linked to adherens junctions by Canoe/afadin helps drive convergent extension. Mol Biol Cell (2011) 1.22
Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling. Mol Biol Cell (2011) 1.21
Exploring the roles of diaphanous and enabled activity in shaping the balance between filopodia and lamellipodia. Mol Biol Cell (2009) 1.20
Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with Fascin. Proc Natl Acad Sci U S A (2014) 1.17
Mammalian septins nomenclature. Mol Biol Cell (2002) 1.16
Rab11 helps maintain apical crumbs and adherens junctions in the Drosophila embryonic ectoderm. PLoS One (2009) 1.16
Original CIN: reviewing roles for APC in chromosome instability. J Cell Biol (2008) 1.10
Enabled and Capping protein play important roles in shaping cell behavior during Drosophila oogenesis. Dev Biol (2009) 1.10
Identification of septin-interacting proteins and characterization of the Smt3/SUMO-conjugation system in Drosophila. J Cell Sci (2002) 1.07
How the cytoskeleton helps build the embryonic body plan: models of morphogenesis from Drosophila. Curr Top Dev Biol (2009) 1.07
CellGeo: a computational platform for the analysis of shape changes in cells with complex geometries. J Cell Biol (2014) 1.04
Rho1 regulates Drosophila adherens junctions independently of p120ctn. Development (2005) 1.04
Genetic and bioinformatic analysis of 41C and the 2R heterochromatin of Drosophila melanogaster: a window on the heterochromatin-euchromatin junction. Genetics (2004) 1.02
Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development. Dev Biol (2007) 1.00
Regulation of epithelial morphogenesis by the G protein-coupled receptor mist and its ligand fog. Sci Signal (2013) 1.00
Regulation of Wnt signaling by the tumor suppressor adenomatous polyposis coli does not require the ability to enter the nucleus or a particular cytoplasmic localization. Mol Biol Cell (2012) 0.92
APC2 and Axin promote mitotic fidelity by facilitating centrosome separation and cytoskeletal regulation. Development (2013) 0.88
Talin autoinhibition is required for morphogenesis. Curr Biol (2013) 0.88
The single Drosophila ZO-1 protein Polychaetoid regulates embryonic morphogenesis in coordination with Canoe/afadin and Enabled. Mol Biol Cell (2011) 0.87
Regulating polarity by directing traffic: Cdc42 prevents adherens junctions from crumblin' aPart. J Cell Biol (2008) 0.87
Putting the model to the test: are APC proteins essential for neuronal polarity, axon outgrowth, and axon targeting? J Cell Biol (2008) 0.87
Rap1 and Canoe/afadin are essential for establishment of apical-basal polarity in the Drosophila embryo. Mol Biol Cell (2013) 0.86
Using Bcr-Abl to examine mechanisms by which abl kinase regulates morphogenesis in Drosophila. Mol Biol Cell (2007) 0.86
Developmental biology: colon construction. Nature (2002) 0.84
Defining components of the ß-catenin destruction complex and exploring its regulation and mechanisms of action during development. PLoS One (2012) 0.82
Cell adhesion: separation of p120's powers? Curr Biol (2007) 0.79
It takes more than two to tango: Dishevelled polymerization and Wnt signaling. Nat Struct Mol Biol (2007) 0.79
Cytoskeletal connections: building strong cells in new ways. Curr Biol (2003) 0.79
Terminal regions of beta-catenin come into view. Structure (2008) 0.78
Wnt signaling: the many interfaces of β-catenin. Curr Biol (2012) 0.76
Cell shape by coercion: Par1 and aPKC put the squeeze on junctions. Dev Cell (2012) 0.75
Cell biology. Arranging a cellular checkerboard. Science (2011) 0.75
Stem cells in the news: CNN and APC make headlines. Dev Cell (2003) 0.75
Morphogenesis: multitalented GTPases seeking new jobs. Curr Biol (2009) 0.75