Published in Biochemistry on March 05, 2002
An enzymatic atavist revealed in dual pathways for water activation. PLoS Biol (2008) 1.52
Elucidation of the proton transport mechanism in human carbonic anhydrase II. J Am Chem Soc (2009) 1.37
Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family. Physiol Rev (2013) 1.35
Chemical rescue of enzymes: proton transfer in mutants of human carbonic anhydrase II. J Am Chem Soc (2011) 1.14
Preferred orientations of His64 in human carbonic anhydrase II. Biochemistry (2007) 1.13
Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase II. Biochemistry (2008) 1.09
Intramolecular proton shuttle supports not only catalytic but also noncatalytic function of carbonic anhydrase II. Proc Natl Acad Sci U S A (2011) 1.04
Proton transfer in catalysis and the role of proton shuttles in carbonic anhydrase. Biochim Biophys Acta (2009) 0.97
Transport activity of the sodium bicarbonate cotransporter NBCe1 is enhanced by different isoforms of carbonic anhydrase. PLoS One (2011) 0.87
Detecting extracellular carbonic anhydrase activity using membrane inlet mass spectrometry. Anal Biochem (2010) 0.84
Probing the surface of human carbonic anhydrase for clues towards the design of isoform specific inhibitors. Biomed Res Int (2015) 0.83
Kinetic and crystallographic studies of the role of tyrosine 7 in the active site of human carbonic anhydrase II. Arch Biochem Biophys (2010) 0.83
Structural insight into activity enhancement and inhibition of H64A carbonic anhydrase II by imidazoles. IUCrJ (2014) 0.82
Location of binding sites in small molecule rescue of human carbonic anhydrase II. Biophys J (2006) 0.82
Effect of active-site mutation at Asn67 on the proton transfer mechanism of human carbonic anhydrase II. Biochemistry (2009) 0.82
Characterization of CamH from Methanosarcina thermophila, founding member of a subclass of the {gamma} class of carbonic anhydrases. J Bacteriol (2009) 0.82
Water networks in fast proton transfer during catalysis by human carbonic anhydrase II. Biochemistry (2012) 0.81
Role of Trp19 and Tyr200 in catalysis by the γ-class carbonic anhydrase from Methanosarcina thermophila. Arch Biochem Biophys (2012) 0.78
Intrinsic proton-donating power of zinc-bound water in a carbonic anhydrase active site model estimated by NMR. J Am Chem Soc (2011) 0.75
Coupling Protein Dynamics with Proton Transport in Human Carbonic Anhydrase II. J Phys Chem B (2016) 0.75
Structure of adeno-associated virus serotype 8, a gene therapy vector. J Virol (2007) 2.15
Entrapment of carbon dioxide in the active site of carbonic anhydrase II. J Biol Chem (2008) 1.98
Structurally mapping the diverse phenotype of adeno-associated virus serotype 4. J Virol (2006) 1.97
Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism. Biochemistry (2007) 1.83
Sex, depression, and risk of hospitalization and mortality in chronic obstructive pulmonary disease. Arch Intern Med (2007) 1.77
Solvent-mediated proton transfer in catalysis by carbonic anhydrase. Acc Chem Res (2007) 1.75
Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II. Biochemistry (2007) 1.72
Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II. Biochemistry (2005) 1.69
Structure of adeno-associated virus type 4. J Virol (2005) 1.47
Heparin binding induces conformational changes in Adeno-associated virus serotype 2. J Struct Biol (2008) 1.44
Structural characterization of the dual glycan binding adeno-associated virus serotype 6. J Virol (2010) 1.42
Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of mice. J Virol (2005) 1.41
The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer. Acta Crystallogr D Biol Crystallogr (2002) 1.39
Elucidation of the proton transport mechanism in human carbonic anhydrase II. J Am Chem Soc (2009) 1.37
A short, strong hydrogen bond in the active site of human carbonic anhydrase II. Biochemistry (2010) 1.33
Crystal structure of nitrated human manganese superoxide dismutase: mechanism of inactivation. Free Radic Biol Med (2005) 1.29
Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease. Biochemistry (2004) 1.28
Neutron structure of human carbonic anhydrase II: implications for proton transfer. Biochemistry (2010) 1.26
Microviridae, a family divided: isolation, characterization, and genome sequence of phiMH2K, a bacteriophage of the obligate intracellular parasitic bacterium Bdellovibrio bacteriovorus. J Bacteriol (2002) 1.24
p37 Induces tumor invasiveness. Mol Cancer Ther (2005) 1.21
Cyr61 suppresses the growth of non-small-cell lung cancer cells via the beta-catenin-c-myc-p53 pathway. Oncogene (2004) 1.19
Ubiquitin-like protein activation. Oncogene (2004) 1.18
Structural insight into the unique properties of adeno-associated virus serotype 9. J Virol (2012) 1.18
Identification of the sialic acid structures recognized by minute virus of mice and the role of binding affinity in virulence adaptation. J Biol Chem (2006) 1.17
Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37. Acta Crystallogr D Biol Crystallogr (2008) 1.17
Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 1.17
Comparative analysis of adeno-associated virus capsid stability and dynamics. J Virol (2013) 1.16
Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution. J Biol Chem (2002) 1.15
Chemical rescue of enzymes: proton transfer in mutants of human carbonic anhydrase II. J Am Chem Soc (2011) 1.14
Carbonic anhydrase in the midgut of larval Aedes aegypti: cloning, localization and inhibition. J Exp Biol (2002) 1.12
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 1. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 1.12
Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir. Biochemistry (2006) 1.11
Carbonic anhydrase in the adult mosquito midgut. J Exp Biol (2005) 1.11
Identification of a novel noncatalytic bicarbonate binding site in eubacterial beta-carbonic anhydrase. Biochemistry (2006) 1.09
Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase II. Biochemistry (2008) 1.09
Suppression of cell proliferation and signaling transduction by connective tissue growth factor in non-small cell lung cancer cells. Mol Cancer Res (2006) 1.09
Neutron structure of human carbonic anhydrase II: a hydrogen-bonded water network "switch" is observed between pH 7.8 and 10.0. Biochemistry (2011) 1.06
Host-selected amino acid changes at the sialic acid binding pocket of the parvovirus capsid modulate cell binding affinity and determine virulence. J Virol (2006) 1.05
Mapping a neutralizing epitope onto the capsid of adeno-associated virus serotype 8. J Virol (2012) 1.05
Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J Virol (2011) 1.04
Assembly and structural analysis of a covalently closed nano-scale DNA cage. Nucleic Acids Res (2007) 1.04
The contribution of naturally occurring polymorphisms in altering the biochemical and structural characteristics of HIV-1 subtype C protease. Biochemistry (2007) 1.04
Intramolecular proton shuttle supports not only catalytic but also noncatalytic function of carbonic anhydrase II. Proc Natl Acad Sci U S A (2011) 1.04
Neutron diffraction of acetazolamide-bound human carbonic anhydrase II reveals atomic details of drug binding. J Am Chem Soc (2012) 1.03
Insights towards sulfonamide drug specificity in α-carbonic anhydrases. Bioorg Med Chem (2012) 1.02
Structural insights into the extracytoplasmic thiamine-binding lipoprotein p37 of Mycoplasma hyorhinis. J Bacteriol (2009) 1.02
Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking. J Virol (2013) 1.01
Capsid antibodies to different adeno-associated virus serotypes bind common regions. J Virol (2013) 1.01
Catalytic and structural effects of amino acid substitution at histidine 30 in human manganese superoxide dismutase: insertion of valine C gamma into the substrate access channel. Biochemistry (2003) 1.01
Origins of enhanced proton transport in the Y7F mutant of human carbonic anhydrase II. J Am Chem Soc (2008) 1.00
Structure of human carnitine acetyltransferase. Molecular basis for fatty acyl transfer. J Biol Chem (2003) 1.00
Glucose deprivation enhances targeting of GLUT1 to lipid rafts in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab (2003) 0.99
The predictive value of epidermal growth factor receptor tests in patients with pulmonary adenocarcinoma: review of current "best evidence" with meta-analysis. Hum Pathol (2008) 0.99
Alkalization of larval mosquito midgut and the role of carbonic anhydrase in different species of mosquitoes. Comp Biochem Physiol C Toxicol Pharmacol (2004) 0.98
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 4. Virology (2003) 0.98
Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer. J Struct Biol (2004) 0.98
Apo-human carbonic anhydrase II revisited: implications of the loss of a metal in protein structure, stability, and solvent network. Biochemistry (2009) 0.98
Proton transfer in catalysis and the role of proton shuttles in carbonic anhydrase. Biochim Biophys Acta (2009) 0.97
Structural annotation of human carbonic anhydrases. J Enzyme Inhib Med Chem (2012) 0.97
Membrane inlet for mass spectrometric measurement of nitric oxide. Free Radic Biol Med (2007) 0.97
Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypes. Acta Crystallogr D Biol Crystallogr (2010) 0.97
Structural mobility in human manganese superoxide dismutase. Biochemistry (2006) 0.96
Genomic evolution in a virus under specific selection for host recognition. Infect Genet Evol (2008) 0.96
Production, purification, crystallization and preliminary X-ray analysis of adeno-associated virus serotype 8. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.96
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 9. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.96
The Escherichia coli clamp loader can actively pry open the β-sliding clamp. J Biol Chem (2011) 0.96
Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 7. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.95
Potent anti-tumor effects of an active site mutant of human manganese-superoxide dismutase. Evolutionary conservation of product inhibition. J Biol Chem (2003) 0.95
Structure of a monoclinic polymorph of human carbonic anhydrase II with a doubled a axis. Acta Crystallogr D Biol Crystallogr (2010) 0.95
High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.94
Lactate flux in astrocytes is enhanced by a non-catalytic action of carbonic anhydrase II. J Physiol (2012) 0.94
Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties. Biochemistry (2009) 0.93
Inhibition of carbonic anhydrase II by thioxolone: a mechanistic and structural study. Biochemistry (2008) 0.93
Human bocavirus capsid structure: insights into the structural repertoire of the parvoviridae. J Virol (2010) 0.93