Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure.

PubWeight™: 2.36‹?› | Rank: Top 2%

🔗 View Article (PMID 11884376)

Published in Circ Res on March 08, 2002

Authors

Shaw-Yung Shai1, Alice E Harpf, Christopher J Babbitt, Maria C Jordan, Michael C Fishbein, Ju Chen, Michelle Omura, Tarek A Leil, K David Becker, Meisheng Jiang, Desmond J Smith, Simon R Cherry, Joseph C Loftus, Robert S Ross

Author Affiliations

1: Department of Physiology, University of California-Los Angeles 90095, USA.

Articles citing this

Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell (2009) 4.21

Mechanical stress-strain sensors embedded in cardiac cytoskeleton: Z disk, titin, and associated structures. Am J Physiol Heart Circ Physiol (2006) 2.37

Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart. Genes Dev (2006) 2.29

Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation. Circulation (2008) 2.21

Molecular basis of physiological heart growth: fundamental concepts and new players. Nat Rev Mol Cell Biol (2013) 1.99

Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure. Genes Dev (2006) 1.80

Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice. J Clin Invest (2009) 1.69

Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy. Mol Cell Biol (2007) 1.63

Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice. J Clin Invest (2005) 1.61

Disruption of mindin exacerbates cardiac hypertrophy and fibrosis. J Mol Med (Berl) (2012) 1.48

Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice. Proc Natl Acad Sci U S A (2008) 1.48

Heterozygous inactivation of the vinculin gene predisposes to stress-induced cardiomyopathy. Am J Pathol (2004) 1.38

Mesenchymal stem cells and cardiac repair. J Cell Mol Med (2008) 1.37

Membrane-associated matrix proteolysis and heart failure. Circ Res (2013) 1.35

Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy. Circ Res (2006) 1.34

IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development. Development (2011) 1.34

A naturally derived cardiac extracellular matrix enhances cardiac progenitor cell behavior in vitro. Acta Biomater (2012) 1.27

PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes. Mol Cell Biol (2005) 1.27

Regulation of cardiac L-type Ca2+ current in Na+-Ca2+ exchanger knockout mice: functional coupling of the Ca2+ channel and the Na+-Ca2+ exchanger. Biophys J (2006) 1.23

ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene. J Am Coll Cardiol (2009) 1.22

Cellular mechanisms of tissue fibrosis. 2. Contributory pathways leading to myocardial fibrosis: moving beyond collagen expression. Am J Physiol Cell Physiol (2012) 1.21

Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways. Circulation (2008) 1.20

Endothelial expression of beta1 integrin is required for embryonic vascular patterning and postnatal vascular remodeling. Mol Cell Biol (2007) 1.19

Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment. Mol Cell Biol (2007) 1.18

Stretch-induced MAP kinase activation in cardiac myocytes: differential regulation through beta1-integrin and focal adhesion kinase. J Mol Cell Cardiol (2007) 1.14

Hypertrophy and heart failure in mice overexpressing the cardiac sodium-calcium exchanger. J Card Fail (2007) 1.11

Deficiency of beta1 integrins results in increased myocardial dysfunction after myocardial infarction. Heart (2006) 1.11

FAK regulates cardiomyocyte survival following ischemia/reperfusion. J Mol Cell Cardiol (2008) 1.11

Intercellular and extracellular mechanotransduction in cardiac myocytes. Pflugers Arch (2011) 1.11

Quantitative N-linked glycoproteomics of myocardial ischemia and reperfusion injury reveals early remodeling in the extracellular environment. Mol Cell Proteomics (2011) 1.09

Significance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated cardiomyopathy. PLoS One (2011) 1.09

Cell communications in the heart. Circulation (2010) 1.09

Cdc42 is an antihypertrophic molecular switch in the mouse heart. J Clin Invest (2009) 1.08

Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality. Circulation (2009) 1.08

Beta1-integrin is required for kidney collecting duct morphogenesis and maintenance of renal function. Am J Physiol Renal Physiol (2009) 1.07

Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog. Circ Res (2008) 1.07

Cardiac myocyte remodeling mediated by N-cadherin-dependent mechanosensing. Am J Physiol Heart Circ Physiol (2011) 1.02

The contribution of cellular mechanotransduction to cardiomyocyte form and function. Biomech Model Mechanobiol (2012) 1.02

Mechanotransduction in cardiac hypertrophy and failure. Circ Res (2015) 1.01

Deletion of Shp2 tyrosine phosphatase in muscle leads to dilated cardiomyopathy, insulin resistance, and premature death. Mol Cell Biol (2008) 1.01

Integrins and integrin-associated proteins in the cardiac myocyte. Circ Res (2014) 1.00

Importance of cell-cell contact in the therapeutic benefits of cardiosphere-derived cells. Stem Cells (2014) 0.99

Vinculin and talin: focus on the myocardium. J Investig Med (2009) 0.99

Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1-Smad signalling. Cardiovasc Res (2011) 0.97

Insulin resistance in striated muscle-specific integrin receptor beta1-deficient mice. J Biol Chem (2008) 0.97

Thrombospondins in the heart: potential functions in cardiac remodeling. J Cell Commun Signal (2009) 0.93

c-Cbl ubiquitin ligase regulates focal adhesion protein turnover and myofibril degeneration induced by neutrophil protease cathepsin G. J Biol Chem (2011) 0.93

β1 integrin gene excision in the adult murine cardiac myocyte causes defective mechanical and signaling responses. Am J Pathol (2012) 0.91

Beta1-adrenergic receptors promote focal adhesion signaling downregulation and myocyte apoptosis in acute volume overload. J Mol Cell Cardiol (2012) 0.90

Integrins protect cardiomyocytes from ischemia/reperfusion injury. J Clin Invest (2013) 0.90

Na/Ca exchange and contraction of the heart. J Mol Cell Cardiol (2013) 0.89

Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload. J Biol Chem (2012) 0.89

Reverse right ventricular structural and extracellular matrix remodeling by estrogen in severe pulmonary hypertension. J Appl Physiol (1985) (2012) 0.89

Hic-5 is required for fetal gene expression and cytoskeletal organization of neonatal cardiac myocytes. J Mol Cell Cardiol (2009) 0.89

Arginine-glycine-aspartic acid (RGD)-containing peptides inhibit the force production of mouse papillary muscle bundles via alpha 5 beta 1 integrin. J Physiol (2005) 0.89

Targeted focal adhesion kinase activation in cardiomyocytes protects the heart from ischemia/reperfusion injury. Arterioscler Thromb Vasc Biol (2012) 0.88

Arrhythmia caused by a Drosophila tropomyosin mutation is revealed using a novel optical coherence tomography instrument. PLoS One (2010) 0.88

Mechanobiology of myofibroblast adhesion in fibrotic cardiac disease. J Cell Sci (2015) 0.88

New frontiers in heart hypertrophy during pregnancy. Am J Cardiovasc Dis (2012) 0.86

Cardiac structural and hemodynamic changes associated with physiological heart hypertrophy of pregnancy are reversed postpartum. J Appl Physiol (1985) (2012) 0.86

Rodent models of heart failure: an updated review. Heart Fail Rev (2013) 0.85

NOX2-derived reactive oxygen species are crucial for CD29-induced pro-survival signalling in cardiomyocytes. Cardiovasc Res (2011) 0.85

A potential role for integrin signaling in mechanoelectrical feedback. Prog Biophys Mol Biol (2012) 0.84

β3 integrin in cardiac fibroblast is critical for extracellular matrix accumulation during pressure overload hypertrophy in mouse. PLoS One (2012) 0.84

Renal studies provide an insight into cardiac extracellular matrix remodeling during health and disease. J Mol Cell Cardiol (2009) 0.84

β-Adrenergic Receptor-Stimulated Cardiac Myocyte Apoptosis: Role of β1 Integrins. J Signal Transduct (2011) 0.83

Pro-survival effect of Dock180 overexpression on rat-derived H9C2 cardiomyocytes. Med Sci Monit Basic Res (2013) 0.82

Intrinsic cardiomyopathy in Marfan syndrome: results from in-vivo and ex-vivo studies of the Fbn1C1039G/+ model and longitudinal findings in humans. Pediatr Res (2015) 0.82

Impaired baroreflex function in mice overexpressing alpha-synuclein. Front Neurol (2013) 0.81

Mechanosensitive channels in striated muscle and the cardiovascular system: not quite a stretch anymore. J Cardiovasc Pharmacol (2009) 0.81

Fermitins, the orthologs of mammalian Kindlins, regulate the development of a functional cardiac syncytium in Drosophila melanogaster. PLoS One (2013) 0.80

Integrins and integrin-related proteins in cardiac fibrosis. J Mol Cell Cardiol (2015) 0.80

Postnatal Loss of Kindlin-2 Leads to Progressive Heart Failure. Circ Heart Fail (2016) 0.79

Emerging anticancer therapeutic targets and the cardiovascular system: is there cause for concern? Circ Res (2010) 0.79

Caveolin and β1-integrin coordinate angiotensinogen expression in cardiac myocytes. Int J Cardiol (2012) 0.78

Expression of ADAM-15 in rat myocardial infarction. Int J Exp Pathol (2009) 0.78

Deep sequence analysis of gene expression identifies osteopontin as a downstream effector of integrin-linked kinase (ILK) in cardiac-specific ILK knockout mice. Circ Heart Fail (2013) 0.78

Embryonic Lethality Due to Arrested Cardiac Development in Psip1/Hdgfrp2 Double-Deficient Mice. PLoS One (2015) 0.78

Caveolin modulates integrin function and mechanical activation in the cardiomyocyte. FASEB J (2014) 0.78

Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection. J Mol Cell Cardiol (2014) 0.78

Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy-Associated Cardiomyopathy. J Am Heart Assoc (2015) 0.78

Mechanical Forces Reshape Differentiation Cues That Guide Cardiomyogenesis. Circ Res (2016) 0.78

Effective treatment of HER2-amplified breast cancer by targeting HER3 and β1 integrin. Breast Cancer Res Treat (2016) 0.77

Quantification of myocyte chemotaxis: a role for FAK in regulating directional motility. Methods Mol Biol (2012) 0.77

Focal adhesion signaling in heart failure. Pflugers Arch (2014) 0.76

Mechanical Regulation of Cardiac Aging in Model Systems. Circ Res (2016) 0.76

Signaling Pathways in Cardiac Myocyte Apoptosis. Biomed Res Int (2016) 0.76

Particularly interesting cysteine- and histidine-rich protein in cardiac development and remodeling. J Investig Med (2009) 0.75

Talin Is Required Continuously for Cardiomyocyte Remodeling during Heart Growth in Drosophila. PLoS One (2015) 0.75

Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish. FASEB J (2015) 0.75

Articles by these authors

Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell (2003) 8.00

Autocrine VEGF signaling is required for vascular homeostasis. Cell (2007) 7.37

A myocardial lineage derives from Tbx18 epicardial cells. Nature (2008) 6.15

Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection. J Heart Lung Transplant (2005) 5.87

MicroPET II: design, development and initial performance of an improved microPET scanner for small-animal imaging. Phys Med Biol (2003) 5.28

ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation. Cell Metab (2005) 4.79

Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet (2008) 4.66

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat Cell Biol (2011) 4.64

LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. Cancer Cell (2013) 4.58

Antibody-mediated rejection criteria - an addition to the Banff 97 classification of renal allograft rejection. Am J Transplant (2003) 4.54

Simultaneous PET-MRI: a new approach for functional and morphological imaging. Nat Med (2008) 4.54

Family-based association between Alzheimer's disease and variants in UBQLN1. N Engl J Med (2005) 4.34

Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell (2009) 4.21

Superoxide flashes in single mitochondria. Cell (2008) 4.08

Depth of interaction resolution measurements for a high resolution PET detector using position sensitive avalanche photodiodes. Phys Med Biol (2006) 4.04

ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell (2005) 3.96

Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection. J Heart Lung Transplant (2007) 3.90

Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest (2006) 3.72

ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med (2002) 3.36

Vascular remodeling of the mouse yolk sac requires hemodynamic force. Development (2007) 3.26

Comparative analysis of proteome and transcriptome variation in mouse. PLoS Genet (2011) 3.23

Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction. J Am Coll Cardiol (2003) 3.20

Selective stimulation of astrocyte calcium in situ does not affect neuronal excitatory synaptic activity. Neuron (2007) 3.15

Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging. Phys Med Biol (2005) 3.11

Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest (2009) 2.98

Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient Mice by altering lymphocyte and macrophage phenotypes. Circ Res (2002) 2.85

Functional adult myocardium in the absence of Na+-Ca2+ exchange: cardiac-specific knockout of NCX1. Circ Res (2004) 2.82

Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells. Dev Biol (2006) 2.81

High-resolution PET detector design: modelling components of intrinsic spatial resolution. Phys Med Biol (2005) 2.73

Spontaneous stellate ganglion nerve activity and ventricular arrhythmia in a canine model of sudden death. Heart Rhythm (2007) 2.62

A prototype PET scanner with DOI-encoding detectors. J Nucl Med (2008) 2.54

Performance test of an LSO-APD detector in a 7-T MRI scanner for simultaneous PET/MRI. J Nucl Med (2006) 2.52

Simultaneous in vivo positron emission tomography and magnetic resonance imaging. Proc Natl Acad Sci U S A (2008) 2.50

Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res (2006) 2.47

Left stellate ganglion and vagal nerve activity and cardiac arrhythmias in ambulatory dogs with pacing-induced congestive heart failure. J Am Coll Cardiol (2007) 2.46

Mechanisms of cardiac nerve sprouting after myocardial infarction in dogs. Circ Res (2004) 2.45

Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. Cell (2013) 2.43

Endothelin-1-induced arrhythmogenic Ca2+ signaling is abolished in atrial myocytes of inositol-1,4,5-trisphosphate(IP3)-receptor type 2-deficient mice. Circ Res (2005) 2.42

Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging. Phys Med Biol (2004) 2.41

Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography. Circulation (2003) 2.37

PET/MR images acquired with a compact MR-compatible PET detector in a 7-T magnet. Radiology (2007) 2.36

Simultaneous acquisition of multislice PET and MR images: initial results with a MR-compatible PET scanner. J Nucl Med (2006) 2.33

Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice. J Clin Invest (2003) 2.23

Neural mechanisms of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia in ambulatory canines. Circulation (2008) 2.20

An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. J Clin Invest (2008) 2.19

Value of high-density endocardial and epicardial mapping for catheter ablation of hemodynamically unstable ventricular tachycardia. Heart Rhythm (2006) 2.18

Ventricular septal rupture after acute myocardial infarction. N Engl J Med (2002) 2.11

Inducible cardiac-restricted expression of enteroviral protease 2A is sufficient to induce dilated cardiomyopathy. Circulation (2006) 2.07

Development and evaluation of a micro- and nanoscale proteomic sample preparation method. J Proteome Res (2005) 2.06

Coronary vasodilation by noninvasive transcutaneous ultrasound: an in vivo canine study. J Am Coll Cardiol (2003) 2.06

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest (2010) 2.04

Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscle. J Cell Biol (2006) 2.00

Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects. Am J Physiol Heart Circ Physiol (2007) 1.99

Sympathetic nerve sprouting, electrical remodeling, and increased vulnerability to ventricular fibrillation in hypercholesterolemic rabbits. Circ Res (2003) 1.97

Evaluation of high performance data acquisition boards for simultaneous sampling of fast signals from PET detectors. Phys Med Biol (2005) 1.95

Characterization of the mouse brain proteome using global proteomic analysis complemented with cysteinyl-peptide enrichment. J Proteome Res (2006) 1.93

T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Development (2005) 1.92

Intracellular calcium dynamics and acceleration of sinus rhythm by beta-adrenergic stimulation. Circulation (2009) 1.91

Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release. Nat Med (2011) 1.88

Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. EMBO J (2004) 1.88

Fabrication and characterization of a 0.5-mm lutetium oxyorthosilicate detector array for high-resolution PET applications. J Nucl Med (2007) 1.87

Cerenkov luminescence tomography for small-animal imaging. Opt Lett (2010) 1.87

Loss of enigma homolog protein results in dilated cardiomyopathy. Circ Res (2010) 1.85

A three-dimensional multispectral fluorescence optical tomography imaging system for small animals based on a conical mirror design. Opt Express (2009) 1.84

Molecular, endocrine, and genetic mechanisms of arterial calcification. Endocr Rev (2004) 1.83

Measurements of wavelength shifting (WLS) fibre readout for a highly multiplexed, depth-encoding PET detector. Phys Med Biol (2007) 1.83

Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. J Clin Invest (2014) 1.82

Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis. Proc Natl Acad Sci U S A (2007) 1.80

Estrogen receptor signaling pathways in human non-small cell lung cancer. Steroids (2007) 1.80

In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature (2013) 1.79

Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis. Mol Genet Metab (2006) 1.77

Lung cancer chemoprevention with celecoxib in former smokers. Cancer Prev Res (Phila) (2011) 1.77

Spatial distribution of nerve sprouting after myocardial infarction in mice. Heart Rhythm (2006) 1.75

Small-animal X-ray dose from micro-CT. Mol Imaging (2004) 1.75

High-throughput imaging of brain gene expression. Genome Res (2002) 1.75

Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children's Oncology Group Pilot Study. J Clin Oncol (2008) 1.75

In vivo detection of macrophages in a rabbit atherosclerotic model by time-resolved laser-induced fluorescence spectroscopy. Atherosclerosis (2005) 1.72

Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene. J Mol Cell Cardiol (2009) 1.72

High-resolution mapping of gene expression using association in an outbred mouse stock. PLoS Genet (2008) 1.72

Pathology of pulmonary antibody-mediated rejection: 2012 update from the Pathology Council of the ISHLT. J Heart Lung Transplant (2013) 1.71

Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells. J Gen Physiol (2010) 1.71

Interleukin-1β is crucial for the induction of coronary artery inflammation in a mouse model of Kawasaki disease. Circulation (2012) 1.70

Autonomic innervation and segmental muscular disconnections at the human pulmonary vein-atrial junction: implications for catheter ablation of atrial-pulmonary vein junction. J Am Coll Cardiol (2006) 1.69

Initial characterization of a dedicated breast PET/CT scanner during human imaging. J Nucl Med (2009) 1.68

Role of the autonomic nervous system in atrial fibrillation: pathophysiology and therapy. Circ Res (2014) 1.68

Mesenchymal stem cell injection induces cardiac nerve sprouting and increased tenascin expression in a Swine model of myocardial infarction. J Cardiovasc Electrophysiol (2003) 1.68

Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injury. J Immunol (2006) 1.68

High resolution mapping of the pulmonary vein and the vein of Marshall during induced atrial fibrillation and atrial tachycardia in a canine model of pacing-induced congestive heart failure. J Am Coll Cardiol (2003) 1.67

Alveolar septal deposition of immunoglobulin and complement parallels pulmonary hemorrhage in a guinea pig model of severe pulmonary leptospirosis. Am J Pathol (2004) 1.66

Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome. Cancer Res (2006) 1.66

Detection of rupture-prone atherosclerotic plaques by time-resolved laser-induced fluorescence spectroscopy. Atherosclerosis (2008) 1.66

Intracellular calcium dynamics and anisotropic reentry in isolated canine pulmonary veins and left atrium. Circulation (2005) 1.65

In vivo Cerenkov luminescence imaging: a new tool for molecular imaging. Philos Trans A Math Phys Eng Sci (2011) 1.64

Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy. Mol Cell Biol (2007) 1.63

Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth. J Cell Biol (2013) 1.63

Light response of retinal ON bipolar cells requires a specific splice variant of Galpha(o). J Neurosci (2002) 1.62