Published in J Immunol on March 15, 2002
Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound. Blood (2008) 1.78
Prenatal ambient air exposure to polycyclic aromatic hydrocarbons and the occurrence of respiratory symptoms over the first year of life. Eur J Epidemiol (2005) 1.48
Nonlinear dose-response relationship in the immune system following exposure to ionizing radiation: mechanisms and implications. Nonlinearity Biol Toxicol Med (2003) 1.32
Aryl hydrocarbon receptor activation reduces dendritic cell function during influenza virus infection. Toxicol Sci (2010) 1.11
The aryl hydrocarbon receptor is required for optimal resistance to Listeria monocytogenes infection in mice. J Immunol (2007) 1.08
The aryl hydrocarbon receptor is a modulator of anti-viral immunity. Biochem Pharmacol (2008) 1.07
Chronic arsenic exposure impairs macrophage functions in the exposed individuals. J Clin Immunol (2009) 1.03
Polycyclic aromatic hydrocarbons and digestive tract cancers: a perspective. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev (2011) 1.03
Consequences of AhR activation in steady-state dendritic cells. Toxicol Sci (2010) 0.96
Dioxin may promote inflammation-related development of endometriosis. Fertil Steril (2008) 0.94
Intrauterine exposure to fine particulate matter as a risk factor for increased susceptibility to acute broncho-pulmonary infections in early childhood. Int J Hyg Environ Health (2013) 0.91
Separate and joint effects of tranplacental and postnatal inhalatory exposure to polycyclic aromatic hydrocarbons: prospective birth cohort study on wheezing events. Pediatr Pulmonol (2013) 0.87
Biomonitoring of polycyclic aromatic hydrocarbon exposure in pregnant women in Trujillo, Peru--comparison of different fuel types used for cooking. Environ Int (2013) 0.85
In vitro atrazine exposure affects the phenotypic and functional maturation of dendritic cells. Toxicol Appl Pharmacol (2007) 0.84
Comparative transcriptomic analyses to scrutinize the assumption that genotoxic PAHs exert effects via a common mode of action. Arch Toxicol (2015) 0.79
Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2. PLoS One (2015) 0.77
Chemical compounds from anthropogenic environment and immune evasion mechanisms: potential interactions. Carcinogenesis (2015) 0.77
Theoretical approach to the innovative mutation of naphthalene 1,2-dioxygenase: a molecular dynamics and docking study. J Mol Model (2014) 0.75
Early circulating lymphocyte apoptosis in human septic shock is associated with poor outcome. Shock (2002) 2.09
The human glutathione transferase alpha locus: genomic organization of the gene cluster and functional characterization of the genetic polymorphism in the hGSTA1 promoter. Pharmacogenetics (2002) 1.68
Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes. Drug Metab Dispos (2006) 1.45
Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin. Cell Immunol (2013) 1.39
Monocyte human leukocyte antigen-DR transcriptional downregulation by cortisol during septic shock. Am J Respir Crit Care Med (2004) 1.36
Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor-alpha or interleukin-6. Drug Metab Dispos (2008) 1.14
Aryl hydrocarbon receptor- and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo[a]pyrene. J Biol Chem (2006) 1.13
Human macrophages constitute targets for immunotoxic inorganic arsenic. J Immunol (2006) 1.13
Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor. Free Radic Biol Med (2004) 1.08
Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation. Toxicol Lett (2008) 1.05
ERK-dependent induction of TNFalpha expression by the environmental contaminant benzo(a)pyrene in primary human macrophages. FEBS Lett (2005) 1.04
Soluble HLA-G molecules are increased in lymphoproliferative disorders. Hum Immunol (2003) 1.03
Polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages. J Immunol (2003) 1.01
MHC class II signaling function is regulated during maturation of plasmacytoid dendritic cells. J Leukoc Biol (2005) 1.00
A role for caspase-8 and c-FLIPL in proliferation and cell-cycle progression of primary hepatocytes. Carcinogenesis (2005) 0.99
Soluble HLA-G inhibits human dendritic cell-triggered allogeneic T-cell proliferation without altering dendritic differentiation and maturation processes. Hum Immunol (2003) 0.97
MHC class II-mediated apoptosis of mature dendritic cells proceeds by activation of the protein kinase C-delta isoenzyme. Int Immunol (2002) 0.97
Transcriptional signature of human macrophages exposed to the environmental contaminant benzo(a)pyrene. Toxicol Sci (2010) 0.96
Inorganic arsenic activates reduced NADPH oxidase in human primary macrophages through a Rho kinase/p38 kinase pathway. J Immunol (2008) 0.95
Soluble HLA-G molecules impair natural killer/dendritic cell crosstalk via inhibition of dendritic cells. Eur J Immunol (2008) 0.95
Soluble HLA-G molecules increase during acute leukemia, especially in subtypes affecting monocytic and lymphoid lineages. Neoplasia (2006) 0.94
Inorganic arsenic impairs proliferation and cytokine expression in human primary T lymphocytes. Toxicology (2012) 0.94
Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line. Eur J Pharm Sci (2006) 0.94
NPC1 repression contributes to lipid accumulation in human macrophages exposed to environmental aryl hydrocarbons. Cardiovasc Res (2009) 0.93
Analysis of drug transporter expression in human intestinal Caco-2 cells by real-time PCR. Fundam Clin Pharmacol (2007) 0.93
Alloreactive CD4+ and CD8+ T cells express the immunotolerant HLA-G molecule in mixed lymphocyte reactions: in vivo implications in transplanted patients. Eur J Immunol (2004) 0.90
Total soluble HLA class I and soluble HLA-G in multiple myeloma and monoclonal gammopathy of undetermined significance. Clin Cancer Res (2005) 0.90
Down-regulation of organic anion transporter expression in human hepatocytes exposed to the proinflammatory cytokine interleukin 1beta. Drug Metab Dispos (2007) 0.89
AhR- and c-maf-dependent induction of beta7-integrin expression in human macrophages in response to environmental polycyclic aromatic hydrocarbons. Biochem Biophys Res Commun (2007) 0.89
Functional expression of sinusoidal drug transporters in primary human and rat hepatocytes. Drug Metab Dispos (2005) 0.89
Global effects of inorganic arsenic on gene expression profile in human macrophages. Mol Immunol (2009) 0.89
Inorganic arsenic alters expression of immune and stress response genes in activated primary human T lymphocytes. Mol Immunol (2011) 0.89
Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway. Mol Pharmacol (2007) 0.88
Differential regulation of drug transporter expression by hepatocyte growth factor in primary human hepatocytes. Drug Metab Dispos (2009) 0.88
Drug transporter expression in human macrophages. Fundam Clin Pharmacol (2011) 0.88
Detection of HLA-G in serum and graft biopsy associated with fewer acute rejections following combined liver-kidney transplantation: possible implications for monitoring patients. Hum Immunol (2003) 0.87
HLA-G and lymphoproliferative disorders. Semin Cancer Biol (2003) 0.87
High level of soluble HLA-G in amniotic fluid is correlated with congenital transmission of Toxoplasma gondii. Clin Immunol (2010) 0.87
Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells. J Biol Chem (2011) 0.86
Blockage of multidrug resistance-associated proteins potentiates the inhibitory effects of arsenic trioxide on CYP1A1 induction by polycyclic aromatic hydrocarbons. J Pharmacol Exp Ther (2003) 0.85
Expression of functional soluble human leucocyte antigen-G molecules in lymphoproliferative disorders. Br J Haematol (2007) 0.85
Inhibition of human mesenchymal stem cell-derived adipogenesis by the environmental contaminant benzo(a)pyrene. Toxicol In Vitro (2009) 0.85
Polarized expression of drug transporters in differentiated human hepatoma HepaRG cells. Toxicol In Vitro (2013) 0.84
Akti-1/2, an allosteric inhibitor of Akt 1 and 2, efficiently inhibits CaMKIα activity and aryl hydrocarbon receptor pathway. Chem Biol Interact (2010) 0.83
Potassium antimonyl tartrate induces caspase- and reactive oxygen species-dependent apoptosis in lymphoid tumoral cells. Br J Haematol (2002) 0.83
Involvement of aryl hydrocarbon receptor in basal and 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced expression of target genes in primary human hepatocytes. Toxicol In Vitro (2010) 0.83
The aryl hydrocarbon receptor is functionally upregulated early in the course of human T-cell activation. Eur J Immunol (2014) 0.83
Major histocompatibility complex abnormalities in non-Hodgkin lymphomas. Br J Haematol (2002) 0.83
Inorganic arsenic represses interleukin-17A expression in human activated Th17 lymphocytes. Toxicol Appl Pharmacol (2012) 0.82
Human endothelial progenitors constitute targets for environmental atherogenic polycyclic aromatic hydrocarbons. Biochem Biophys Res Commun (2006) 0.82
Cytochrome P450-dependent toxicity of environmental polycyclic aromatic hydrocarbons towards human macrophages. Biochem Biophys Res Commun (2004) 0.81
Arsenic trioxide induces apoptosis of human monocytes during macrophagic differentiation through nuclear factor-kappaB-related survival pathway down-regulation. J Pharmacol Exp Ther (2005) 0.81
Regulation of drug transporter mRNA expression by interferon-γ in primary human hepatocytes. Fundam Clin Pharmacol (2011) 0.80
Regulation of drug transporter expression by oncostatin M in human hepatocytes. Biochem Pharmacol (2011) 0.80
Loss of heterozygosity, a frequent but a non-exclusive mechanism responsible for HLA dysregulation in non-Hodgkin's lymphomas. Br J Haematol (2004) 0.80
Activation of the aryl hydrocarbon receptor by the calcium/calmodulin-dependent protein kinase kinase inhibitor 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid (STO-609). Drug Metab Dispos (2008) 0.80
A new lactoferrin- and iron-dependent lysosomal death pathway is induced by benzo[a]pyrene in hepatic epithelial cells. Toxicol Appl Pharmacol (2008) 0.80
TNFalpha- and NF-kappaB-dependent induction of the chemokine CCL1 in human macrophages exposed to the atherogenic lipoprotein(a). Life Sci (2009) 0.79
The mitochondrial fluorescent dye rhodamine 123 is a high-affinity substrate for organic cation transporters (OCTs) 1 and 2. Fundam Clin Pharmacol (2012) 0.79
Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha. Carcinogenesis (2005) 0.79
Identification of Na+/H+ exchange as a new target for toxic polycyclic aromatic hydrocarbons. FASEB J (2003) 0.79
Inorganic arsenic induces necrosis of human CD34-positive haematopoietic stem cells. Environ Toxicol (2008) 0.79
Indoleamine 2,3-dioxygenase activity as a potential biomarker of immune suppression during visceral leishmaniasis. Innate Immun (2013) 0.79
Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells. Chem Biol Interact (2007) 0.78
Redox-sensitive regulation of gene expression in human primary macrophages exposed to inorganic arsenic. J Cell Biochem (2009) 0.78
MAPK- and PKC/CREB-dependent induction of interleukin-11 by the environmental contaminant formaldehyde in human bronchial epithelial cells. Toxicology (2011) 0.78
RNAi-based screening identifies kinases interfering with dioxin-mediated up-regulation of CYP1A1 activity. PLoS One (2011) 0.78
Oltipraz regulates different categories of genes relevant to chemoprevention in human hepatocytes. Carcinogenesis (2004) 0.77
Regulation of hepatic drug transporter activity and expression by organochlorine pesticides. J Biochem Mol Toxicol (2013) 0.77