Published in J Virol on April 01, 2002
Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme. Crit Rev Biochem Mol Biol (2008) 5.26
Two Chikungunya isolates from the outbreak of La Reunion (Indian Ocean) exhibit different patterns of infection in the mosquito, Aedes albopictus. PLoS One (2007) 4.95
Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion. Proc Natl Acad Sci U S A (2003) 2.83
Influenza virus can enter and infect cells in the absence of clathrin-mediated endocytosis. J Virol (2002) 2.78
Virus entry, assembly, budding, and membrane rafts. Microbiol Mol Biol Rev (2003) 2.68
Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry. J Virol (2003) 1.92
A structural and functional perspective of alphavirus replication and assembly. Future Microbiol (2009) 1.72
Herpes simplex virus glycoprotein B associates with target membranes via its fusion loops. J Virol (2009) 1.65
Role of cholesterol in human immunodeficiency virus type 1 envelope protein-mediated fusion with host cells. J Virol (2002) 1.64
Independent segregation of human immunodeficiency virus type 1 Gag protein complexes and lipid rafts. J Virol (2003) 1.55
Role for influenza virus envelope cholesterol in virus entry and infection. J Virol (2003) 1.47
Alphavirus Entry and Membrane Fusion. Viruses (2010) 1.31
A conserved histidine in the ij loop of the Semliki Forest virus E1 protein plays an important role in membrane fusion. J Virol (2004) 1.30
Lipids as modulators of membrane fusion mediated by viral fusion proteins. Eur Biophys J (2007) 1.29
Role of conserved histidine residues in the low-pH dependence of the Semliki Forest virus fusion protein. J Virol (2009) 1.24
Multistep regulation of membrane insertion of the fusion peptide of Semliki Forest virus. J Virol (2004) 1.23
Second-site revertants of a Semliki Forest virus fusion-block mutation reveal the dynamics of a class II membrane fusion protein. J Virol (2006) 1.20
Transition from hemifusion to pore opening is rate limiting for vacuole membrane fusion. J Cell Biol (2005) 1.19
Characterization of a membrane-associated trimeric low-pH-induced Form of the class II viral fusion protein E from tick-borne encephalitis virus and its crystallization. J Virol (2004) 1.19
Endocytosis of chikungunya virus into mammalian cells: role of clathrin and early endosomal compartments. PLoS One (2010) 1.16
Low pH-dependent hepatitis C virus membrane fusion depends on E2 integrity, target lipid composition, and density of virus particles. J Biol Chem (2009) 1.14
Requirements for CEACAMs and cholesterol during murine coronavirus cell entry. J Virol (2004) 1.12
A stable prefusion intermediate of the alphavirus fusion protein reveals critical features of class II membrane fusion. Cell Host Microbe (2008) 1.11
Novel mutations that control the sphingolipid and cholesterol dependence of the Semliki Forest virus fusion protein. J Virol (2002) 1.11
Differential cholesterol binding by class II fusion proteins determines membrane fusion properties. J Virol (2008) 1.06
Arenavirus entry occurs through a cholesterol-dependent, non-caveolar, clathrin-mediated endocytic mechanism. Virology (2007) 1.05
Nuclear envelope remnants: fluid membranes enriched in sterols and polyphosphoinositides. PLoS One (2009) 0.99
Replication of alphaviruses: a review on the entry process of alphaviruses into cells. Adv Virol (2011) 0.96
Murine coronavirus requires lipid rafts for virus entry and cell-cell fusion but not for virus release. J Virol (2005) 0.96
Purification and crystallization reveal two types of interactions of the fusion protein homotrimer of Semliki Forest virus. J Virol (2004) 0.93
Syntaxin is efficiently excluded from sphingomyelin-enriched domains in supported lipid bilayers containing cholesterol. J Membr Biol (2003) 0.92
Cholesterol dependence of HTLV-I infection. AIDS Res Hum Retroviruses (2005) 0.90
Mosquito cellular factors and functions in mediating the infectious entry of chikungunya virus. PLoS Negl Trop Dis (2013) 0.90
Biophysical characterization and membrane interaction of the two fusion loops of glycoprotein B from herpes simplex type I virus. PLoS One (2012) 0.89
Early Events in Chikungunya Virus Infection-From Virus CellBinding to Membrane Fusion. Viruses (2015) 0.89
Site-directed antibodies against the stem region reveal low pH-induced conformational changes of the Semliki Forest virus fusion protein. J Virol (2006) 0.89
Aggregatibacter actinomycetemcomitans leukotoxin utilizes a cholesterol recognition/amino acid consensus site for membrane association. J Biol Chem (2013) 0.85
Pseudorevertants of a Semliki forest virus fusion-blocking mutation reveal a critical interchain interaction in the core trimer. J Virol (2010) 0.83
Function of membrane rafts in viral lifecycles and host cellular response. Biochem Res Int (2011) 0.82
Reversible acid-induced inactivation of the membrane fusion protein of Semliki Forest virus. J Virol (2005) 0.79
Glycoprotein B of herpes simplex virus 2 has more than one intracellular conformation and is altered by low pH. J Virol (2012) 0.76
Functional rafts in cell membranes. Nature (1997) 38.89
Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell (1992) 17.81
The alphaviruses: gene expression, replication, and evolution. Microbiol Rev (1994) 16.68
Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol (1998) 14.83
The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution. Nature (1995) 12.25
Structure and function of sphingolipid- and cholesterol-rich membrane rafts. J Biol Chem (2000) 9.96
Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER. Nat Cell Biol (2001) 8.93
Nucleotide sequence of cdna coding for Semliki Forest virus membrane glycoproteins. Nature (1980) 8.07
The caveolae membrane system. Annu Rev Biochem (1998) 7.54
Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts. J Virol (2000) 6.47
The Fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH. Cell (2001) 5.65
Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain. EMBO J (1997) 5.52
Cellular cholesterol efflux mediated by cyclodextrins. J Biol Chem (1995) 4.86
Influenza viruses select ordered lipid domains during budding from the plasma membrane. J Biol Chem (1999) 4.83
Use of cyclodextrins for manipulating cellular cholesterol content. J Lipid Res (1997) 4.44
Membrane fusion activity of the influenza virus hemagglutinin. The low pH-induced conformational change. J Biol Chem (1985) 4.32
SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis. EMBO J (2001) 4.32
VIP21/caveolin is a cholesterol-binding protein. Proc Natl Acad Sci U S A (1995) 3.97
Reconstitution of Semliki forest virus membrane. J Cell Biol (1977) 3.68
Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles. Nat Cell Biol (2000) 3.55
Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane. Biochem J (1998) 3.22
The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation. Biochemistry (2000) 3.11
pH-induced alterations in the fusogenic spike protein of Semliki Forest virus. J Cell Biol (1985) 2.98
The mechanism of membrane insertion for a cholesterol-dependent cytolysin: a novel paradigm for pore-forming toxins. Cell (1999) 2.89
A single point mutation controls the cholesterol dependence of Semliki Forest virus entry and exit. J Cell Biol (1998) 2.65
SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis. Proc Natl Acad Sci U S A (2001) 2.48
Structures and mechanisms in flavivirus fusion. Adv Virus Res (2000) 2.36
Role of cholesterol in fusion of Semliki Forest virus with membranes. J Virol (1984) 2.32
Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes. J Cell Biol (1999) 2.30
Mutagenesis of the putative fusion domain of the Semliki Forest virus spike protein. J Virol (1991) 2.30
Mechanisms of mutations inhibiting fusion and infection by Semliki Forest virus. J Cell Biol (1996) 2.25
Membrane fusion and the alphavirus life cycle. Adv Virus Res (1995) 2.18
Palmitoylation of the HIV-1 envelope glycoprotein is critical for viral infectivity. Proc Natl Acad Sci U S A (2000) 2.11
Role of membrane organization and membrane domains in endocytic lipid trafficking. Traffic (2000) 2.02
Membrane and protein interactions of a soluble form of the Semliki Forest virus fusion protein. J Virol (1994) 2.00
Membrane fusion of Semliki Forest virus requires sphingolipids in the target membrane. EMBO J (1994) 1.99
Biosynthesis, maturation, and acid activation of the Semliki Forest virus fusion protein. J Virol (1990) 1.95
Measles virus assembly within membrane rafts. J Virol (2000) 1.65
Caveolin transfection results in caveolae formation but not apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins in epithelial cells. J Cell Biol (1998) 1.51
Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts). Proc Natl Acad Sci U S A (2001) 1.51
Expression and characterization of recombinant caveolin. Purification by polyhistidine tagging and cholesterol-dependent incorporation into defined lipid membranes. J Biol Chem (1996) 1.47
Specific roles for lipids in virus fusion and exit. Examples from the alphaviruses. Subcell Biochem (2000) 1.46
Biochemical consequences of a mutation that controls the cholesterol dependence of Semliki Forest virus fusion. J Virol (2000) 1.42
Formation and characterization of the trimeric form of the fusion protein of Semliki Forest Virus. J Virol (2000) 1.31
Caveolins and cellular cholesterol balance. Traffic (2000) 1.29
Semliki forest virus budding: assay, mechanisms, and cholesterol requirement. J Virol (2000) 1.27
Fusion of Semliki Forest virus with cholesterol-containing liposomes at low pH: a specific requirement for sphingolipids. Mol Membr Biol (1995) 1.26
Interaction of digitonin and its analogs with membrane cholesterol. J Biochem (1984) 1.13
An epitope of the Semliki Forest virus fusion protein exposed during virus-membrane fusion. J Virol (1999) 1.10
Cholesterol-depleted cells that are relatively permissive for Semliki Forest virus infection. Virology (1996) 1.08
Molecular dissection of the Semliki Forest virus homotrimer reveals two functionally distinct regions of the fusion protein. J Virol (2002) 1.02
Differential roles of two conserved glycine residues in the fusion peptide of Semliki Forest virus. Virology (2001) 0.85
Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus. Nature (2004) 4.02
Treatment of non-small-cell lung cancer with erlotinib or gefitinib. N Engl J Med (2011) 3.74
Domain III from class II fusion proteins functions as a dominant-negative inhibitor of virus membrane fusion. J Cell Biol (2005) 1.88
Visualization of the target-membrane-inserted fusion protein of Semliki Forest virus by combined electron microscopy and crystallography. Cell (2003) 1.67
Dealing with low pH: entry and exit of alphaviruses and flaviviruses. Trends Microbiol (2009) 1.60
The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J Clin Invest (2011) 1.59
miR-200 Inhibits lung adenocarcinoma cell invasion and metastasis by targeting Flt1/VEGFR1. Mol Cancer Res (2010) 1.54
Furin processing and proteolytic activation of Semliki Forest virus. J Virol (2003) 1.40
Targets of the tumor suppressor miR-200 in regulation of the epithelial-mesenchymal transition in cancer. Cancer Res (2011) 1.37
A conserved histidine in the ij loop of the Semliki Forest virus E1 protein plays an important role in membrane fusion. J Virol (2004) 1.30
ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression. J Clin Invest (2012) 1.29
Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer. Cancer Discov (2013) 1.27
Role of conserved histidine residues in the low-pH dependence of the Semliki Forest virus fusion protein. J Virol (2009) 1.24
Multistep regulation of membrane insertion of the fusion peptide of Semliki Forest virus. J Virol (2004) 1.23
ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism. J Clin Invest (2014) 1.22
The role of epithelial-mesenchymal transition programming in invasion and metastasis: a clinical perspective. Cancer Manag Res (2013) 1.22
Ubiquitin depletion and dominant-negative VPS4 inhibit rhabdovirus budding without affecting alphavirus budding. J Virol (2007) 1.21
Second-site revertants of a Semliki Forest virus fusion-block mutation reveal the dynamics of a class II membrane fusion protein. J Virol (2006) 1.20
A stable prefusion intermediate of the alphavirus fusion protein reveals critical features of class II membrane fusion. Cell Host Microbe (2008) 1.11
Novel mutations that control the sphingolipid and cholesterol dependence of the Semliki Forest virus fusion protein. J Virol (2002) 1.11
A synthetic matrix with independently tunable biochemistry and mechanical properties to study epithelial morphogenesis and EMT in a lung adenocarcinoma model. Cancer Res (2012) 1.09
In vitro reconstitution reveals key intermediate states of trimer formation by the dengue virus membrane fusion protein. J Virol (2010) 1.07
Differential cholesterol binding by class II fusion proteins determines membrane fusion properties. J Virol (2008) 1.06
Distinct biological roles for the notch ligands Jagged-1 and Jagged-2. J Biol Chem (2009) 1.06
A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion. PLoS Pathog (2013) 1.05
Molecular dissection of the Semliki Forest virus homotrimer reveals two functionally distinct regions of the fusion protein. J Virol (2002) 1.02
Flaviviruses: braking the entering. Curr Opin Virol (2013) 1.02
In vitro and in vivo studies identify important features of dengue virus pr-E protein interactions. PLoS Pathog (2010) 1.02
Functions of the stem region of the Semliki Forest virus fusion protein during virus fusion and assembly. J Virol (2006) 1.01
E1 mutants identify a critical region in the trimer interface of the Semliki forest virus fusion protein. J Virol (2009) 0.97
Effects of membrane potential and sphingolipid structures on fusion of Semliki Forest virus. J Virol (2002) 0.97
Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor γ2 expression. Mol Cell Biol (2011) 0.96
Mutations that promote furin-independent growth of Semliki Forest virus affect p62-E1 interactions and membrane fusion. Virology (2004) 0.96
The domain I-domain III linker plays an important role in the fusogenic conformational change of the alphavirus membrane fusion protein. J Virol (2011) 0.94
Purification and crystallization reveal two types of interactions of the fusion protein homotrimer of Semliki Forest virus. J Virol (2004) 0.93
Gene expression profile of A549 cells from tissue of 4D model predicts poor prognosis in lung cancer patients. Int J Cancer (2013) 0.89
Site-directed antibodies against the stem region reveal low pH-induced conformational changes of the Semliki Forest virus fusion protein. J Virol (2006) 0.89
Fibulin-2 is a driver of malignant progression in lung adenocarcinoma. PLoS One (2013) 0.89
Imaging of the alphavirus capsid protein during virus replication. J Virol (2013) 0.88
The conserved glycine residues in the transmembrane domain of the Semliki Forest virus fusion protein are not required for assembly and fusion. Virology (2005) 0.88
An interaction site of the envelope proteins of Semliki Forest virus that is preserved after proteolytic activation. Virology (2005) 0.87
Pseudorevertants of a Semliki forest virus fusion-blocking mutation reveal a critical interchain interaction in the core trimer. J Virol (2010) 0.83
Structural biology: An alphavirus puzzle solved. Nature (2010) 0.82
Dysregulation of cell polarity proteins synergize with oncogenes or the microenvironment to induce invasive behavior in epithelial cells. PLoS One (2012) 0.82
Fusion induced by a class II viral fusion protein, semliki forest virus E1, is dependent on the voltage of the target cell. J Virol (2007) 0.82
The interaction of alphavirus E1 protein with exogenous domain III defines stages in virus-membrane fusion. J Virol (2011) 0.81
A key interaction between the alphavirus envelope proteins responsible for initial dimer dissociation during fusion. J Virol (2013) 0.80
The role of E3 in pH protection during alphavirus assembly and exit. J Virol (2013) 0.79
Through the open door: Preferential binding of dasatinib to the active form of BCR-ABL unveiled by in silico experiments. Mol Oncol (2013) 0.78
Identification of a specific region in the e1 fusion protein involved in zinc inhibition of semliki forest virus fusion. J Virol (2012) 0.78
Cross-inhibition of chikungunya virus fusion and infection by alphavirus E1 domain III proteins. J Virol (2013) 0.77
Alphavirus entry: NRAMP leads the way. Cell Host Microbe (2011) 0.76
Five-gene signature in non-small-cell lung cancer. N Engl J Med (2007) 0.75
Epithelial-to-mesenchymal transition drives a pro-metastatic Golgi compaction process through scaffolding protein PAQR11. J Clin Invest (2016) 0.75