Published in J Biol Chem on March 08, 2002
Basement membranes: cell scaffoldings and signaling platforms. Cold Spring Harb Perspect Biol (2011) 2.73
Developmental and pathogenic mechanisms of basement membrane assembly. Curr Pharm Des (2009) 1.80
Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells. Nat Commun (2012) 1.70
Enhanced laminin binding by alpha-dystroglycan after enzymatic deglycosylation. Biochem J (2005) 1.56
Laminin-sulfatide binding initiates basement membrane assembly and enables receptor signaling in Schwann cells and fibroblasts. J Cell Biol (2005) 1.46
Laminins in basement membrane assembly. Cell Adh Migr (2012) 1.44
Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction. J Cell Biol (2008) 1.34
Complex interactions between the laminin alpha 4 subunit and integrins regulate endothelial cell behavior in vitro and angiogenesis in vivo. Proc Natl Acad Sci U S A (2002) 1.31
Crystal structure and cell surface anchorage sites of laminin alpha1LG4-5. J Biol Chem (2007) 1.27
Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies. Skelet Muscle (2011) 1.08
Schwann cell myelination requires integration of laminin activities. J Cell Sci (2012) 1.00
Scaffold-forming and Adhesive Contributions of Synthetic Laminin-binding Proteins to Basement Membrane Assembly. J Biol Chem (2009) 0.97
Distinct roles for laminin globular domains in laminin alpha1 chain mediated rescue of murine laminin alpha2 chain deficiency. PLoS One (2010) 0.96
Laminin-induced activation of Rac1 and JNKp46 is initiated by Src family kinases and mimics the effects of skeletal muscle contraction. Biochemistry (2007) 0.94
Crystal structure of the LG1-3 region of the laminin alpha2 chain. J Biol Chem (2009) 0.92
Laminin-211 in skeletal muscle function. Cell Adh Migr (2012) 0.92
Transgenic overexpression of the proprotein convertase furin enhances skin tumor growth. Neoplasia (2012) 0.91
Monolayer culturing and cloning of human pluripotent stem cells on laminin-521-based matrices under xeno-free and chemically defined conditions. Nat Protoc (2014) 0.90
Mammalian and Drosophila cells adhere to the laminin alpha4 LG4 domain through syndecans, but not glypicans. Biochem J (2004) 0.89
Laminin isoforms containing the gamma3 chain are unable to bind to integrins due to the absence of the glutamic acid residue conserved in the C-terminal regions of the gamma1 and gamma2 chains. J Biol Chem (2008) 0.88
The molecular evolution of the pif family proteins in various species of mollusks. Mar Biotechnol (NY) (2012) 0.86
Proregenerative properties of ECM molecules. Biomed Res Int (2013) 0.85
The potential of sarcospan in adhesion complex replacement therapeutics for the treatment of muscular dystrophy. FEBS J (2013) 0.85
Enhanced UV-induced skin carcinogenesis in transgenic mice overexpressing proprotein convertases. Neoplasia (2013) 0.83
Laminin-121--recombinant expression and interactions with integrins. Matrix Biol (2010) 0.83
Activated Notch1 maintains the phenotype of radial glial cells and promotes their adhesion to laminin by upregulating nidogen. Glia (2008) 0.82
Chain-specific heparin-binding sequences in the laminin alpha chain LG45 modules. Biochemistry (2009) 0.81
LG4-5 domains of laminin-211 binds alpha-dystroglycan to allow myotube attachment and prevent anoikis. J Cell Physiol (2010) 0.79
Identification of cell adhesive sequences in the N-terminal region of the laminin α2 chain. J Biol Chem (2012) 0.78
Chimeric protein repair of laminin polymerization ameliorates muscular dystrophy phenotype. J Clin Invest (2017) 0.78
A biologically active sequence of the laminin alpha2 large globular 1 domain promotes cell adhesion through syndecan-1 by inducing phosphorylation and membrane localization of protein kinase Cdelta. J Biol Chem (2009) 0.77
Laminin-α1 LG4-5 domain binding to dystroglycan mediates muscle cell survival, growth, and the AP-1 and NF-κB transcription factors but also has adverse effects. Am J Physiol Cell Physiol (2011) 0.77
Structural basis of laminin binding to the LARGE glycans on dystroglycan. Nat Chem Biol (2016) 0.77
Transformed MDCK cells secrete elevated MMP1 that generates LAMA5 fragments promoting endothelial cell angiogenesis. Sci Rep (2016) 0.75
The genetics of mammalian circadian order and disorder: implications for physiology and disease. Nat Rev Genet (2008) 7.65
Alport's syndrome, Goodpasture's syndrome, and type IV collagen. N Engl J Med (2003) 4.77
Genomic instability in laminopathy-based premature aging. Nat Med (2005) 4.54
Laminin functions in tissue morphogenesis. Annu Rev Cell Dev Biol (2004) 4.22
A simplified laminin nomenclature. Matrix Biol (2005) 3.81
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice. Nat Genet (2002) 3.78
Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511. Nat Biotechnol (2010) 3.70
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation. Nature (2005) 3.31
The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation. Dev Cell (2006) 3.10
Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation. Proc Natl Acad Sci U S A (2007) 3.06
Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation. Genes Dev (2003) 2.68
Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia. Nature (2012) 2.52
The scavenger receptor MARCO is required for lung defense against pneumococcal pneumonia and inhaled particles. J Exp Med (2004) 2.46
Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation. J Cell Biol (2002) 2.34
X-linked Alport syndrome: natural history and genotype-phenotype correlations in girls and women belonging to 195 families: a "European Community Alport Syndrome Concerted Action" study. J Am Soc Nephrol (2003) 2.12
MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis. PLoS Pathog (2009) 2.12
Identification of the circadian transcriptome in adult mouse skeletal muscle. Physiol Genomics (2007) 2.06
The role of laminin in embryonic cell polarization and tissue organization. Dev Cell (2003) 2.05
Clustering-induced tyrosine phosphorylation of nephrin by Src family kinases. Kidney Int (2003) 2.03
Genotype/phenotype correlations of NPHS1 and NPHS2 mutations in nephrotic syndrome advocate a functional inter-relationship in glomerular filtration. Hum Mol Genet (2002) 1.85
Laminin isoforms in tumor invasion, angiogenesis and metastasis. Semin Cancer Biol (2002) 1.83
Recurrence of nephrotic syndrome in kidney grafts of patients with congenital nephrotic syndrome of the Finnish type: role of nephrin. Transplantation (2002) 1.83
Deletion of the laminin alpha4 chain leads to impaired microvessel maturation. Mol Cell Biol (2002) 1.81
New susceptibility loci associated with kidney disease in type 1 diabetes. PLoS Genet (2012) 1.79
New insights into the role of podocytes in proteinuria. Nat Rev Nephrol (2009) 1.77
Gamma-actin is required for cytoskeletal maintenance but not development. Proc Natl Acad Sci U S A (2009) 1.74
Nephrin--a unique structural and signaling protein of the kidney filter. Trends Mol Med (2007) 1.74
Large-scale identification of genes implicated in kidney glomerulus development and function. EMBO J (2006) 1.69
Cytoplasmic gamma-actin contributes to a compensatory remodeling response in dystrophin-deficient muscle. Proc Natl Acad Sci U S A (2006) 1.68
Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography. J Clin Invest (2004) 1.67
MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis. Dev Cell (2012) 1.65
CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function. Proc Natl Acad Sci U S A (2010) 1.63
Laminin-511 but not -332, -111, or -411 enables mouse embryonic stem cell self-renewal in vitro. Stem Cells (2008) 1.62
Genome of the long-living sacred lotus (Nelumbo nucifera Gaertn.). Genome Biol (2013) 1.59
Enhanced laminin binding by alpha-dystroglycan after enzymatic deglycosylation. Biochem J (2005) 1.56
MARCO is the major binding receptor for unopsonized particles and bacteria on human alveolar macrophages. J Immunol (2005) 1.53
Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney. EMBO J (2003) 1.53
Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus. J Exp Med (2007) 1.53
Protection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/II. J Clin Invest (2007) 1.52
Role of laminin terminal globular domains in basement membrane assembly. J Biol Chem (2007) 1.50
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival. J Clin Invest (2011) 1.49
Construction of a high-density genetic map for grape using next generation restriction-site associated DNA sequencing. BMC Plant Biol (2012) 1.47
β-Actin specifically controls cell growth, migration, and the G-actin pool. Mol Biol Cell (2011) 1.46
Laminin-sulfatide binding initiates basement membrane assembly and enables receptor signaling in Schwann cells and fibroblasts. J Cell Biol (2005) 1.46
Functional diversity of laminins. Annu Rev Cell Dev Biol (2012) 1.45
Time- and exercise-dependent gene regulation in human skeletal muscle. Genome Biol (2003) 1.44
Utrophin binds laterally along actin filaments and can couple costameric actin with sarcolemma when overexpressed in dystrophin-deficient muscle. Mol Biol Cell (2002) 1.44
Laminins in basement membrane assembly. Cell Adh Migr (2012) 1.44
Cytoplasmic gamma-actin is not required for skeletal muscle development but its absence leads to a progressive myopathy. Dev Cell (2006) 1.43
Site mapping and characterization of O-glycan structures on alpha-dystroglycan isolated from rabbit skeletal muscle. J Biol Chem (2010) 1.43
Distinctive functions of membrane type 1 matrix-metalloprotease (MT1-MMP or MMP-14) in lung and submandibular gland development are independent of its role in pro-MMP-2 activation. Dev Biol (2005) 1.42
Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo. EMBO Rep (2011) 1.40
The actin gene family: function follows isoform. Cytoskeleton (Hoboken) (2010) 1.39
Contribution of alpha6 integrins to hematopoietic stem and progenitor cell homing to bone marrow and collaboration with alpha4 integrins. Blood (2006) 1.39
A site on laminin alpha 5, AQARSAASKVKVSMKF, induces inflammatory cell production of matrix metalloproteinase-9 and chemotaxis. J Immunol (2003) 1.38
Dystrophin is a microtubule-associated protein. J Cell Biol (2009) 1.38
Association testing of previously reported variants in a large case-control meta-analysis of diabetic nephropathy. Diabetes (2012) 1.36
Nuclear envelope defects cause stem cell dysfunction in premature-aging mice. J Cell Biol (2008) 1.36
Impaired angiogenesis, delayed wound healing and retarded tumor growth in perlecan heparan sulfate-deficient mice. Cancer Res (2004) 1.36
Dystrophin and utrophin bind actin through distinct modes of contact. J Biol Chem (2006) 1.36
Nephrin promotes cell-cell adhesion through homophilic interactions. Am J Pathol (2003) 1.36
Co-localization of nephrin, podocin, and the actin cytoskeleton: evidence for a role in podocyte foot process formation. Am J Pathol (2002) 1.34
PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage. J Cell Sci (2005) 1.34
Expression and subcellular distribution of novel glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2, and 2310066E14Rik. J Am Soc Nephrol (2007) 1.33
SR-A/MARCO-mediated ligand delivery enhances intracellular TLR and NLR function, but ligand scavenging from cell surface limits TLR4 response to pathogens. Blood (2010) 1.33
Functional substitution by TAT-utrophin in dystrophin-deficient mice. PLoS Med (2009) 1.30
β-actin and γ-actin are each dispensable for auditory hair cell development but required for Stereocilia maintenance. PLoS Genet (2010) 1.30
Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development. Dev Dyn (2007) 1.30
Heparan sulfate of perlecan is involved in glomerular filtration. J Am Soc Nephrol (2005) 1.28
Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse. Vis Neurosci (2007) 1.27
Crystal structure and cell surface anchorage sites of laminin alpha1LG4-5. J Biol Chem (2007) 1.27
A reverse genetic screen in the zebrafish identifies crb2b as a regulator of the glomerular filtration barrier. Dev Biol (2009) 1.26
Integrins are required for the differentiation of visceral endoderm. J Cell Sci (2009) 1.26
Recombinant human laminin-10 (alpha5beta1gamma1). Production, purification, and migration-promoting activity on vascular endothelial cells. J Biol Chem (2002) 1.26
Molecular dissection of the alpha-dystroglycan- and integrin-binding sites within the globular domain of human laminin-10. J Biol Chem (2003) 1.26
N-linked glycosylation is critical for the plasma membrane localization of nephrin. J Am Soc Nephrol (2002) 1.25
Structural insight into the complex formation of latent matrix metalloproteinase 2 with tissue inhibitor of metalloproteinase 2. Proc Natl Acad Sci U S A (2002) 1.24
Intronic miR-301 feedback regulates its host gene, ska2, in A549 cells by targeting MEOX2 to affect ERK/CREB pathways. Biochem Biophys Res Commun (2010) 1.23
Molecular make-up of the glomerular filtration barrier. Biochem Biophys Res Commun (2010) 1.23
Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs. EMBO J (2002) 1.22
Cardiomyopathy associated with microcirculation dysfunction in laminin alpha4 chain-deficient mice. J Biol Chem (2005) 1.22
Analysis of integrin functions in peri-implantation embryos, hematopoietic system, and skin. Methods Enzymol (2007) 1.21
Glcci1 deficiency leads to proteinuria. J Am Soc Nephrol (2011) 1.19
Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria. Cell Metab (2012) 1.18
Laminin assembles into separate basement membrane and fibrillar matrices in Schwann cells. J Cell Sci (2002) 1.17
An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells. Nat Commun (2013) 1.17
MicroRNA-200b regulates cyclin D1 expression and promotes S-phase entry by targeting RND3 in HeLa cells. Mol Cell Biochem (2010) 1.15
Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation. Circ Res (2008) 1.15
Crystal structure of the cysteine-rich domain of scavenger receptor MARCO reveals the presence of a basic and an acidic cluster that both contribute to ligand recognition. J Biol Chem (2007) 1.15
Zebrafish: a model system for the study of vertebrate renal development, function, and pathophysiology. Curr Opin Nephrol Hypertens (2011) 1.14
Combining use of a panel of ssDNA aptamers in the detection of Staphylococcus aureus. Nucleic Acids Res (2009) 1.14
Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin. J Biol Chem (2003) 1.13
The utrophin actin-binding domain binds F-actin in two different modes: implications for the spectrin superfamily of proteins. J Cell Biol (2002) 1.12
Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin-Darby canine kidney cells. J Biol Chem (2004) 1.12
Characterization of recombinant soluble macrophage scavenger receptor MARCO. J Biol Chem (2002) 1.12