Published in J Am Chem Soc on March 20, 2002
Collagen structure and stability. Annu Rev Biochem (2009) 4.62
An electronic effect on protein structure. Protein Sci (2003) 2.04
n-->pi* interactions in proteins. Nat Chem Biol (2010) 2.02
Prolyl 4-hydroxylase. Crit Rev Biochem Mol Biol (2010) 1.99
Nature of amide carbonyl--carbonyl interactions in proteins. J Am Chem Soc (2009) 1.89
Stereoelectronic effects on polyproline conformation. Protein Sci (2006) 1.57
Energetics of an n --> pi interaction that impacts protein structure. Org Lett (2006) 1.50
n --> pi* Interaction and n)(pi Pauli repulsion are antagonistic for protein stability. J Am Chem Soc (2010) 1.37
New strategies for the design of folded peptoids revealed by a survey of noncovalent interactions in model systems. J Am Chem Soc (2009) 1.27
Signature of n→π* interactions in α-helices. Protein Sci (2011) 1.25
An evaluation of peptide-bond isosteres. Chembiochem (2011) 1.22
Reciprocity of steric and stereoelectronic effects in the collagen triple helix. J Am Chem Soc (2006) 1.17
Stereoelectronic and steric effects in side chains preorganize a protein main chain. Proc Natl Acad Sci U S A (2009) 1.17
Spatio-temporal modification of collagen scaffolds mediated by triple helical propensity. Biomacromolecules (2008) 1.13
4-chloroprolines: synthesis, conformational analysis, and effect on the collagen triple helix. Biopolymers (2008) 1.13
Solution structure of an ABC collagen heterotrimer reveals a single-register helix stabilized by electrostatic interactions. J Biol Chem (2009) 1.11
2005 Emil Thomas Kaiser Award. Protein Sci (2006) 1.11
n→π* interactions of amides and thioamides: implications for protein stability. J Am Chem Soc (2013) 1.08
Stabilization of the collagen triple helix by O-methylation of hydroxyproline residues. J Am Chem Soc (2008) 1.06
Conformational preferences of substrates for human prolyl 4-hydroxylase. Biochemistry (2008) 1.05
Synthesis and biological applications of collagen-model triple-helical peptides. Org Biomol Chem (2010) 1.05
Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides. Amino Acids (2010) 0.99
An n→π* interaction in aspirin: implications for structure and reactivity. J Org Chem (2011) 0.97
Proline editing: a general and practical approach to the synthesis of functionally and structurally diverse peptides. Analysis of steric versus stereoelectronic effects of 4-substituted prolines on conformation within peptides. J Am Chem Soc (2013) 0.94
Origin of the stability conferred upon collagen by fluorination. Bioorg Med Chem Lett (2009) 0.93
The aberrance of the 4S diastereomer of 4-hydroxyproline. J Am Chem Soc (2010) 0.92
Signatures of n→π* interactions in proteins. Protein Sci (2014) 0.88
n→π* interactions engender chirality in carbonyl groups. Org Lett (2014) 0.86
Intimate interactions with carbonyl groups: dipole-dipole or n→π*? J Org Chem (2012) 0.86
O-acylation of hydroxyproline residues: effect on peptide-bond isomerization and collagen stability. Biopolymers (2005) 0.85
Trans-cis switching mechanisms in proline analogues and their relevance for the gating of the 5-HT3 receptor. J Phys Chem B (2009) 0.85
Triple helical structure and stabilization of collagen-like molecules with 4(R)-hydroxyproline in the Xaa position. Biophys J (2005) 0.84
Peptides that anneal to natural collagen in vitro and ex vivo. Org Biomol Chem (2012) 0.83
Electronic properties of amino acid side chains: quantum mechanics calculation of substituent effects. BMC Chem Biol (2005) 0.82
A conserved interaction with the chromophore of fluorescent proteins. Protein Sci (2011) 0.82
Collagen-like peptides and peptide-polymer conjugates in the design of assembled materials. Eur Polym J (2013) 0.81
Practical syntheses of 4-fluoroprolines. J Fluor Chem (2008) 0.81
An n→π* interaction reduces the electrophilicity of the acceptor carbonyl group. Chem Commun (Camb) (2013) 0.81
Excitation-dependent visible fluorescence in decameric nanoparticles with monoacylglycerol cluster chromophores. Nat Commun (2013) 0.79
Rational design of protein stability: effect of (2S,4R)-4-fluoroproline on the stability and folding pathway of ubiquitin. PLoS One (2011) 0.79
Pyramidalization of a carbonyl C atom in (2S)-N-(seleno-acet-yl)proline methyl ester. Acta Crystallogr Sect E Struct Rep Online (2013) 0.79
Stabilization of collagen-model, triple-helical peptides for in vitro and in vivo applications. Methods Mol Biol (2013) 0.78
Interstrand dipole-dipole interactions can stabilize the collagen triple helix. J Biol Chem (2011) 0.78
Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines. J Org Chem (2011) 0.76
n→π* Interactions Are Competitive with Hydrogen Bonds. Org Lett (2016) 0.76
Crystal structure of N-(3-oxo-butano-yl)-l-homoserine lactone. Acta Crystallogr E Crystallogr Commun (2016) 0.76
Replacing a single atom accelerates the folding of a protein and increases its thermostability. Org Biomol Chem (2016) 0.76
Non-covalent interactions: Fold globally, bond locally. Nat Chem Biol (2010) 0.76
4-Fluoroprolines: Conformational Analysis and Effects on the Stability and Folding of Peptides and Proteins. Top Heterocycl Chem (2016) 0.76
4-ketoproline: An electrophilic proline analog for bioconjugation. Biopolymers (2015) 0.75
H12461. Fluorine as a Regiocontrol Element in the Ring Openings of Bicyclic Aziridiniums. Helv Chim Acta (2012) 0.75
Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective αvβ1 Integrin Inhibitors. ACS Med Chem Lett (2016) 0.75
Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics. J Org Chem (2012) 0.75
(2S,4R)- and (2S,4S)-perfluoro-tert-butyl 4-hydroxyproline: two conformationally distinct proline amino acids for sensitive application in 19F NMR. J Org Chem (2014) 0.75
Concise syntheses of enantiomerically pure protected 4-hydroxypyroglutamic acid and 4-hydroxyproline from a nitroso-cyclopentadiene cycloadduct. Tetrahedron Asymmetry (2008) 0.75
Stronger and (now) longer synthetic collagen. Adv Exp Med Biol (2009) 0.75
The n→π* Interaction. Acc Chem Res (2017) 0.75
Protein folding, misfolding and aggregation: The importance of two-electron stabilizing interactions. PLoS One (2017) 0.75
Geometrical frustration as a potential design principle for peptide-based assemblies. Interface Focus (2017) 0.75
The worldwide Protein Data Bank (wwPDB): ensuring a single, uniform archive of PDB data. Nucleic Acids Res (2006) 13.44
The CCPN data model for NMR spectroscopy: development of a software pipeline. Proteins (2005) 13.03
BioMagResBank. Nucleic Acids Res (2007) 10.21
Metabolite identification via the Madison Metabolomics Consortium Database. Nat Biotechnol (2008) 5.12
Remediation of the protein data bank archive. Nucleic Acids Res (2007) 4.89
Collagen structure and stability. Annu Rev Biochem (2009) 4.62
Bright ideas for chemical biology. ACS Chem Biol (2008) 3.84
RECOORD: a recalculated coordinate database of 500+ proteins from the PDB using restraints from the BioMagResBank. Proteins (2005) 3.41
Identification of transcribed sequences in Arabidopsis thaliana by using high-resolution genome tiling arrays. Proc Natl Acad Sci U S A (2005) 3.21
Probabilistic interaction network of evidence algorithm and its application to complete labeling of peak lists from protein NMR spectroscopy. PLoS Comput Biol (2009) 3.01
BioMagResBank database with sets of experimental NMR constraints corresponding to the structures of over 1400 biomolecules deposited in the Protein Data Bank. J Biomol NMR (2003) 2.74
BioMagResBank databases DOCR and FRED containing converted and filtered sets of experimental NMR restraints and coordinates from over 500 protein PDB structures. J Biomol NMR (2005) 2.71
Method for determining molar concentrations of metabolites in complex solutions from two-dimensional 1H-13C NMR spectra. Anal Chem (2007) 2.46
Hydrolytic stability of hydrazones and oximes. Angew Chem Int Ed Engl (2008) 2.45
Outcome of a workshop on archiving structural models of biological macromolecules. Structure (2006) 2.32
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol Cell (2011) 2.29
Project management system for structural and functional proteomics: Sesame. J Struct Funct Genomics (2003) 2.19
Pathway for polyarginine entry into mammalian cells. Biochemistry (2004) 2.14
An electronic effect on protein structure. Protein Sci (2003) 2.04
n-->pi* interactions in proteins. Nat Chem Biol (2010) 2.02
Prolyl 4-hydroxylase. Crit Rev Biochem Mol Biol (2010) 1.99
Nature of amide carbonyl--carbonyl interactions in proteins. J Am Chem Soc (2009) 1.89
rNMR: open source software for identifying and quantifying metabolites in NMR spectra. Magn Reson Chem (2009) 1.84
High-resolution iterative frequency identification for NMR as a general strategy for multidimensional data collection. J Am Chem Soc (2005) 1.79
Linear analysis of carbon-13 chemical shift differences and its application to the detection and correction of errors in referencing and spin system identifications. J Biomol NMR (2005) 1.78
Cell-free protein production and labeling protocol for NMR-based structural proteomics. Nat Methods (2004) 1.78
Solution structure of the N-domain of Wilson disease protein: distinct nucleotide-binding environment and effects of disease mutations. Proc Natl Acad Sci U S A (2006) 1.72
Chemical synthesis of proteins. Annu Rev Biophys Biomol Struct (2005) 1.71
Insights on the conformational stability of collagen. Nat Prod Rep (2002) 1.71
Auto-induction medium for the production of [U-15N]- and [U-13C, U-15N]-labeled proteins for NMR screening and structure determination. Protein Expr Purif (2005) 1.65
Simple chemical transformation of lignocellulosic biomass into furans for fuels and chemicals. J Am Chem Soc (2009) 1.63
Protein energetic conformational analysis from NMR chemical shifts (PECAN) and its use in determining secondary structural elements. J Biomol NMR (2005) 1.62
Self-assembly of synthetic collagen triple helices. Proc Natl Acad Sci U S A (2006) 1.61
Advances in Bioconjugation. Curr Org Chem (2010) 1.60
PINE-SPARKY: graphical interface for evaluating automated probabilistic peak assignments in protein NMR spectroscopy. Bioinformatics (2009) 1.59
Fermentable sugars by chemical hydrolysis of biomass. Proc Natl Acad Sci U S A (2010) 1.57
Stereoelectronic effects on polyproline conformation. Protein Sci (2006) 1.57
Recommendations of the wwPDB NMR Validation Task Force. Structure (2013) 1.57
Stereoelectronic and steric effects in the collagen triple helix: toward a code for strand association. J Am Chem Soc (2005) 1.56
Probabilistic Identification of Spin Systems and their Assignments including Coil-Helix Inference as Output (PISTACHIO). J Biomol NMR (2005) 1.56
Ribonuclease inhibitor: structure and function. Prog Nucleic Acid Res Mol Biol (2005) 1.55
Translocation of a beta-peptide across cell membranes. J Am Chem Soc (2002) 1.55
Fluorogenic label for biomolecular imaging. ACS Chem Biol (2006) 1.54
Simultaneous quantification and identification of individual chemicals in metabolite mixtures by two-dimensional extrapolated time-zero (1)H-(13)C HSQC (HSQC(0)). J Am Chem Soc (2011) 1.53
Stereoelectronic effects on collagen stability: the dichotomy of 4-fluoroproline diastereomers. J Am Chem Soc (2003) 1.53
Reaction mechanism and kinetics of the traceless Staudinger ligation. J Am Chem Soc (2006) 1.52
The Protein Data Bank at 40: reflecting on the past to prepare for the future. Structure (2012) 1.51
Energetics of an n --> pi interaction that impacts protein structure. Org Lett (2006) 1.50
Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles. Sci Transl Med (2014) 1.50
Ribonuclease inhibitor as an intracellular sentry. Nucleic Acids Res (2003) 1.45
Addressing the intrinsic disorder bottleneck in structural proteomics. Proteins (2005) 1.44
Bright building blocks for chemical biology. ACS Chem Biol (2014) 1.44
Structural basis for the photoconversion of a phytochrome to the activated Pfr form. Nature (2010) 1.42
Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein. J Mol Biol (2007) 1.41
Solution structure of a ubiquitin-like domain from tubulin-binding cofactor B. J Biol Chem (2004) 1.40
n --> pi* Interaction and n)(pi Pauli repulsion are antagonistic for protein stability. J Am Chem Soc (2010) 1.37
Structural rearrangement of human lymphotactin, a C chemokine, under physiological solution conditions. J Biol Chem (2002) 1.36
Structure and dynamics of the iron-sulfur cluster assembly scaffold protein IscU and its interaction with the cochaperone HscB. Biochemistry (2009) 1.36
Site-specific protein immobilization by Staudinger ligation. J Am Chem Soc (2003) 1.35
The future of the Protein Data Bank. Biopolymers (2012) 1.34
Inductive Effects on the Energetics of Prolyl Peptide Bond Isomerization: Implications for Collagen Folding and Stability. J Am Chem Soc (1996) 1.32
Electronic basis of improper hydrogen bonding: a subtle balance of hyperconjugation and rehybridization. J Am Chem Soc (2003) 1.31
Ribonucleases as novel chemotherapeutics : the ranpirnase example. BioDrugs (2008) 1.31
The NMR restraints grid at BMRB for 5,266 protein and nucleic acid PDB entries. J Biomol NMR (2009) 1.30
Intrinsically disordered gamma-subunit of cGMP phosphodiesterase encodes functionally relevant transient secondary and tertiary structure. Proc Natl Acad Sci U S A (2008) 1.30
Peptide bond isosteres: ester or (E)-alkene in the backbone of the collagen triple helix. Org Lett (2005) 1.29
Semisynthesis and characterization of mammalian thioredoxin reductase. Biochemistry (2006) 1.28
Bovine pancreatic ribonuclease: fifty years of the first enzymatic reaction mechanism. Biochemistry (2011) 1.27
Comparison of cell-based and cell-free protocols for producing target proteins from the Arabidopsis thaliana genome for structural studies. Proteins (2005) 1.26
Signature of n→π* interactions in α-helices. Protein Sci (2011) 1.25
Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs. J Am Chem Soc (2007) 1.25
Arginine grafting to endow cell permeability. ACS Chem Biol (2007) 1.24
Polyarginine as a multifunctional fusion tag. Protein Sci (2005) 1.24
Solution structures of spinach acyl carrier protein with decanoate and stearate. Biochemistry (2006) 1.23
Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity. Curr Pharm Biotechnol (2008) 1.23
An evaluation of peptide-bond isosteres. Chembiochem (2011) 1.22
Tuning the pK(a) of fluorescein to optimize binding assays. Anal Chem (2007) 1.22
Olefin metathesis for chemical biology. Curr Opin Chem Biol (2008) 1.21
Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn. J Am Chem Soc (2002) 1.20
The Protein Data Bank archive as an open data resource. J Comput Aided Mol Des (2014) 1.20
Wheat germ cell-free platform for eukaryotic protein production. FEBS J (2006) 1.19
Effect of 3-hydroxyproline residues on collagen stability. J Am Chem Soc (2003) 1.19
Secretory ribonucleases are internalized by a dynamin-independent endocytic pathway. J Cell Sci (2003) 1.18
Disordered form of the scaffold protein IscU is the substrate for iron-sulfur cluster assembly on cysteine desulfurase. Proc Natl Acad Sci U S A (2011) 1.17
Reciprocity of steric and stereoelectronic effects in the collagen triple helix. J Am Chem Soc (2006) 1.17
Stereoelectronic and steric effects in side chains preorganize a protein main chain. Proc Natl Acad Sci U S A (2009) 1.17
Identifying latent enzyme activities: substrate ambiguity within modern bacterial sugar kinases. Biochemistry (2004) 1.17
Deconvolution of two-dimensional NMR spectra by fast maximum likelihood reconstruction: application to quantitative metabolomics. Anal Chem (2011) 1.17
Latent fluorophore based on the trimethyl lock. J Am Chem Soc (2005) 1.16
The sigma-1 receptor protects against cellular oxidative stress and activates antioxidant response elements. Eur J Pharmacol (2012) 1.16
Stable isotope assisted assignment of elemental compositions for metabolomics. Anal Chem (2007) 1.16
Dynamics and metal ion binding in the U6 RNA intramolecular stem-loop as analyzed by NMR. J Mol Biol (2005) 1.15
Prevention of aggregation after refolding by balanced stabilization-destabilization: production of the Arabidopsis thaliana protein APG8a (At4g21980) for NMR structure determination. Protein Expr Purif (2004) 1.15
Robust, integrated computational control of NMR experiments to achieve optimal assignment by ADAPT-NMR. PLoS One (2012) 1.15
Protein assembly by orthogonal chemical ligation methods. J Am Chem Soc (2003) 1.14
Water-soluble phosphinothiols for traceless staudinger ligation and integration with expressed protein ligation. J Am Chem Soc (2007) 1.14
Solution structure of a cyanobacterial phytochrome GAF domain in the red-light-absorbing ground state. J Mol Biol (2008) 1.14
Staudinger ligation of alpha-azido acids retains stereochemistry. J Org Chem (2002) 1.13
4-chloroprolines: synthesis, conformational analysis, and effect on the collagen triple helix. Biopolymers (2008) 1.13