Published in Semin Nephrol on March 01, 2002
A comprehensive view of sex-specific issues related to cardiovascular disease. CMAJ (2007) 2.35
Blood pressure and heart rate QTL in mice of the B6/D2 lineage: sex differences and environmental influences. Physiol Genomics (2008) 0.81
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
SLC2A9 is a high-capacity urate transporter in humans. PLoS Med (2008) 2.87
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet (2010) 2.24
Gender-linked hypertension in offspring of lard-fed pregnant rats. Hypertension (2003) 2.00
Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats. Stroke (2009) 1.71
A microRNA guide for clinicians and basic scientists: background and experimental techniques. Heart Lung Circ (2011) 1.60
Genetic dissection of a blood pressure quantitative trait locus on rat chromosome 1 and gene expression analysis identifies SPON1 as a novel candidate hypertension gene. Circ Res (2007) 1.53
Genetic determinants of metabolic syndrome components in the stroke-prone spontaneously hypertensive rat. J Hypertens (2005) 1.53
The epithelial sodium channel γ-subunit gene and blood pressure: family based association, renal gene expression, and physiological analyses. Hypertension (2011) 1.50
Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats. Mol Ther (2004) 1.50
Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure. J Hypertens (2009) 1.44
Gene expression profiling reveals renin mRNA overexpression in human hypertensive kidneys and a role for microRNAs. Hypertension (2011) 1.36
Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra. J Cereb Blood Flow Metab (2008) 1.35
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nat Genet (2013) 1.30
T2*-weighted magnetic resonance imaging with hyperoxia in acute ischemic stroke. Ann Neurol (2010) 1.24
Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array. Hypertension (2010) 1.22
Comparative and functional analyses of LYL1 loci establish marsupial sequences as a model for phylogenetic footprinting. Genomics (2003) 1.17
Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding. PLoS One (2009) 1.16
A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock. Genome Res (2008) 1.13
Essential hypertension and beta2-adrenergic receptor gene: linkage and association analysis. Hypertension (2002) 1.11
Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. Validation using [14C]2-deoxyglucose autoradiography. J Cereb Blood Flow Metab (2011) 1.10
Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion. J Cereb Blood Flow Metab (2011) 1.04
A common variant in low-density lipoprotein receptor-related protein 6 gene (LRP6) is associated with LDL-cholesterol. Arterioscler Thromb Vasc Biol (2009) 1.04
Fibroblast growth factor 1 gene and hypertension: from the quantitative trait locus to positional analysis. Circulation (2007) 1.02
Differential effects of 17beta-estradiol upon stroke damage in stroke prone and normotensive rats. J Cereb Blood Flow Metab (2004) 1.02
Detrimental effects of 17beta-oestradiol after permanent middle cerebral artery occlusion. J Cereb Blood Flow Metab (2005) 1.02
Genetics of hypertension: from experimental animals to humans. Biochim Biophys Acta (2009) 1.00
Myogenic and structural properties of cerebral arteries from the stroke-prone spontaneously hypertensive rat. Am J Physiol Heart Circ Physiol (2003) 0.99
Combined antiapoptotic and antioxidant approach to acute neuroprotection for stroke in hypertensive rats. J Cereb Blood Flow Metab (2013) 0.98
Strikingly low circulating CRP concentrations in ultramarathon runners independent of markers of adiposity: how low can you go? Arterioscler Thromb Vasc Biol (2003) 0.98
Onset of experimental severe cardiac fibrosis is mediated by overexpression of Angiotensin-converting enzyme 2. Hypertension (2009) 0.97
Exercise: putting action into our epigenome. Sports Med (2014) 0.97
Male-specific region of the Y chromosome and cardiovascular risk: phylogenetic analysis and gene expression studies. Arterioscler Thromb Vasc Biol (2013) 0.96
Validation of uromodulin as a candidate gene for human essential hypertension. Hypertension (2013) 0.96
Effects of 17beta-oestradiol on cerebral ischaemic damage and lipid peroxidation. Brain Res (2005) 0.95
Reduction of Gstm1 expression in the stroke-prone spontaneously hypertension rat contributes to increased oxidative stress. Hypertension (2005) 0.95
Pathway analysis shows association between FGFBP1 and hypertension. J Am Soc Nephrol (2011) 0.95
Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor. Hypertension (2011) 0.95
Epistatic interaction between beta2-adrenergic receptor and neuropeptide Y genes influences LDL-cholesterol in hypertension. Hypertension (2004) 0.94
Penumbra detection using PWI/DWI mismatch MRI in a rat stroke model with and without comorbidity: comparison of methods. J Cereb Blood Flow Metab (2012) 0.93
Estrogen receptor beta agonist diarylpropiolnitrile (DPN) does not mediate neuroprotection in a rat model of permanent focal ischemia. Brain Res (2007) 0.92
Functional genomics in rodent models of hypertension. J Physiol (2004) 0.92
Neuroinflammation and neuroprotective strategies in acute ischaemic stroke - from bench to bedside. Curr Mol Med (2009) 0.92
Longer leukocyte telomeres are associated with ultra-endurance exercise independent of cardiovascular risk factors. PLoS One (2013) 0.91
Microarray analysis of rat chromosome 2 congenic strains. Hypertension (2002) 0.91
Sphingosine-1-phosphate-induced inflammation involves receptor tyrosine kinase transactivation in vascular cells: upregulation in hypertension. Hypertension (2011) 0.91
Novel MRI detection of the ischemic penumbra: direct assessment of metabolic integrity. NMR Biomed (2011) 0.90
Perfluorocarbons enhance a T2*-based MRI technique for identifying the penumbra in a rat model of acute ischemic stroke. J Cereb Blood Flow Metab (2013) 0.90
Studies of an association in boys of blood pressure and the Y chromosome. Am J Hypertens (2007) 0.90
Genetic aspects of stroke: human and experimental studies. J Cereb Blood Flow Metab (2002) 0.90
Estrogen is neuroprotective via an apolipoprotein E-dependent mechanism in a mouse model of global ischemia. J Cereb Blood Flow Metab (2002) 0.89
Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats. Stroke (2008) 0.89
Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo. Hum Gene Ther (2004) 0.88
Influence of 100% and 40% oxygen on penumbral blood flow, oxygen level, and T2*-weighted MRI in a rat stroke model. J Cereb Blood Flow Metab (2011) 0.88
Positive impact of pre-stroke surgery on survival following transient focal ischemia in hypertensive rats. J Neurosci Methods (2012) 0.87
An MRI-histological study of white matter in stroke-free SHRSP. J Cereb Blood Flow Metab (2013) 0.87
Watermaze performance after middle cerebral artery occlusion in the rat: the role of sensorimotor versus memory impairments. J Cereb Blood Flow Metab (2012) 0.86
Detection of ischemic penumbra using combined perfusion and T2* oxygen challenge imaging. Int J Stroke (2014) 0.86
A novel interaction between sympathetic overactivity and aberrant regulation of renin by miR-181a in BPH/2J genetically hypertensive mice. Hypertension (2013) 0.85
Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function. J Hypertens (2014) 0.85
Targeting endothelial cells with adenovirus expressing nitric oxide synthase prevents elevation of blood pressure in stroke-prone spontaneously hypertensive rats. Mol Ther (2005) 0.85
Sex-specific differences in cerebral arterial myogenic tone in hypertensive and normotensive rats. Am J Physiol Heart Circ Physiol (2005) 0.85
Noninvasive MRI measurement of CBF: evaluating an arterial spin labelling sequence with 99mTc-HMPAO CBF autoradiography in a rat stroke model. J Cereb Blood Flow Metab (2012) 0.84
17beta-Estradiol treatment following permanent focal ischemia does not influence recovery of sensorimotor function. Neurobiol Dis (2006) 0.83
Association between lipid profile and circulating concentrations of estrogens in young men. Atherosclerosis (2008) 0.83
Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke. Neuropathol Appl Neurobiol (2014) 0.82
Genetic information in the diagnosis and treatment of hypertension. Curr Hypertens Rep (2006) 0.81
Corcoran Lecture. Cardiovascular genomics and oxidative stress. Hypertension (2005) 0.81
Interaction between chromosome 2 and 3 regulates pulse pressure in the stroke-prone spontaneously hypertensive rat. Hypertension (2013) 0.81
FGF21 signalling pathway and metabolic traits - genetic association analysis. Eur J Hum Genet (2010) 0.81
Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats. J Hypertens (2002) 0.81
Serum C-reactive protein and lipids in ultra-Marathon runners. Am J Cardiol (2004) 0.80
Estrogen treatment enhances nitric oxide bioavailability in normotensive but not hypertensive rats. Am J Hypertens (2006) 0.80
Regional and temporal variations in tissue sodium concentration during the acute stroke phase. Magn Reson Med (2011) 0.80
New method for the quantitative assessment of axonal damage in focal cerebral ischemia. J Cereb Blood Flow Metab (2002) 0.80
Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension. Cardiovasc Res (2012) 0.79
Vascular-targeting antioxidant therapy in a model of hypertension and stroke. J Cardiovasc Pharmacol (2010) 0.79
Serial postmortem relaxometry in the normal rat brain and following stroke. J Magn Reson Imaging (2008) 0.79
Complexities of oestrogen in stroke. Clin Sci (Lond) (2009) 0.78
Functional genomics in hypertension. Curr Opin Nephrol Hypertens (2006) 0.78
GADD34 gene restores virulence in viral vector used in experimental stroke study. J Cereb Blood Flow Metab (2007) 0.78
A double-tuned (1)H/(23)Na dual resonator system for tissue sodium concentration measurements in the rat brain via Na-MRI. Phys Med Biol (2010) 0.78
Translational perspectives on perfusion-diffusion mismatch in ischemic stroke. Int J Stroke (2013) 0.78
Hyperglycemia accelerates apparent diffusion coefficient-defined lesion growth after focal cerebral ischemia in rats with and without features of metabolic syndrome. J Cereb Blood Flow Metab (2013) 0.78
No involvement of the nerve growth factor gene locus in hypertension in spontaneously hypertensive rats. Hypertens Res (2005) 0.77