Published in Ann Neurol on March 01, 2002
Exercise enhances learning and hippocampal neurogenesis in aged mice. J Neurosci (2005) 7.14
An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus. Proc Natl Acad Sci U S A (2007) 5.30
Neural mechanisms of ageing and cognitive decline. Nature (2010) 3.59
A pathophysiological framework of hippocampal dysfunction in ageing and disease. Nat Rev Neurosci (2011) 3.23
Pattern separation in the hippocampus. Trends Neurosci (2011) 3.21
Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging. Proc Natl Acad Sci U S A (2004) 2.39
Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults. Hippocampus (2010) 2.39
Neurocognitive aging: prior memories hinder new hippocampal encoding. Trends Neurosci (2006) 2.20
Source monitoring 15 years later: what have we learned from fMRI about the neural mechanisms of source memory? Psychol Bull (2009) 1.97
Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48. Sci Transl Med (2013) 1.97
Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxid Redox Signal (2012) 1.96
The brain in the age of old: the hippocampal formation is targeted differentially by diseases of late life. Ann Neurol (2008) 1.92
Age-related memory deficits linked to circuit-specific disruptions in the hippocampus. Proc Natl Acad Sci U S A (2011) 1.88
Individual differences in spatial pattern separation performance associated with healthy aging in humans. Learn Mem (2010) 1.77
Brain aging and its modifiers: insights from in vivo neuromorphometry and susceptibility weighted imaging. Ann N Y Acad Sci (2007) 1.62
Vulnerable neural systems and the borderland of brain aging and neurodegeneration. Neuron (2013) 1.54
Altered hippocampal transcript profile accompanies an age-related spatial memory deficit in mice. Learn Mem (2004) 1.43
Hippocampal atrophy and ventricular enlargement in normal aging, mild cognitive impairment (MCI), and Alzheimer Disease. Alzheimer Dis Assoc Disord (2012) 1.40
Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults. Nat Neurosci (2014) 1.20
Medial temporal lobe BOLD activity at rest predicts individual differences in memory ability in healthy young adults. Proc Natl Acad Sci U S A (2008) 1.18
Linking hippocampal structure and function to memory performance in an aging population. Arch Neurol (2009) 1.17
Hippocampal volume and shape analysis in an older adult population. Clin Neuropsychol (2007) 1.08
Spatial pattern separation in cognitively normal young and older adults. Hippocampus (2012) 1.02
Characterizing cognitive aging in humans with links to animal models. Front Aging Neurosci (2012) 1.01
Impact of aging brain circuits on cognition. Eur J Neurosci (2013) 1.00
The impact of flavonoids on spatial memory in rodents: from behaviour to underlying hippocampal mechanisms. Genes Nutr (2009) 0.99
II. Temporal patterns of longitudinal change in aging brain function. Neurobiol Aging (2006) 0.99
Differential effects of age and history of hypertension on regional brain volumes and iron. Neuroimage (2010) 0.94
Mechanisms of age-related cognitive change and targets for intervention: epigenetics. J Gerontol A Biol Sci Med Sci (2012) 0.93
Memory decline: the boundary between aging and age-related disease. Ann Neurol (2002) 0.92
Older and wiser? An affective science perspective on age-related challenges in financial decision making. Soc Cogn Affect Neurosci (2010) 0.92
New Neurons in Aging Brains: Molecular Control by Small Non-Coding RNAs. Front Neurosci (2012) 0.91
Less efficient pattern separation may contribute to age-related spatial memory deficits. Front Aging Neurosci (2012) 0.90
Virtual navigation strategies from childhood to senescence: evidence for changes across the life span. Front Aging Neurosci (2012) 0.89
Neural Protein Synthesis during Aging: Effects on Plasticity and Memory. Front Aging Neurosci (2010) 0.84
Isolating pathogenic mechanisms embedded within the hippocampal circuit through regional vulnerability. Neuron (2014) 0.84
The effects of aging on memory for sequentially presented objects in rats. Behav Neurosci (2009) 0.83
Vascular plasticity and cognition during normal aging and dementia. JAMA Neurol (2015) 0.83
Learning and generalization in healthy aging: implication for frontostriatal and hippocampal function. Cogn Behav Neurol (2012) 0.83
Hippocampal neurogenesis: Learning to remember. Prog Neurobiol (2016) 0.82
Age-related changes in place learning for adjacent and separate locations. Neurobiol Aging (2013) 0.81
Spatial memory deficit across aging: current insights of the role of 5-HT7 receptors. Front Behav Neurosci (2015) 0.81
Structural imaging in early pre-states of dementia. Biochim Biophys Acta (2011) 0.81
Naming ability changes in physiological and pathological aging. Front Neurosci (2012) 0.81
Attenuated long-term Arc expression in the aged fascia dentata. Neurobiol Aging (2010) 0.81
Visual object pattern separation varies in older adults. Learn Mem (2013) 0.81
Context Memory Decline in Middle Aged Adults is Related to Changes in Prefrontal Cortex Function. Cereb Cortex (2015) 0.81
Age-related changes in Egr1 transcription and DNA methylation within the hippocampus. Hippocampus (2016) 0.80
Hippocampal gene expression meta-analysis identifies aging and age-associated spatial learning impairment (ASLI) genes and pathways. PLoS One (2013) 0.79
Memory for sequences of events impaired in typical aging. Learn Mem (2015) 0.78
Could androgens maintain specific domains of mental health in aging men by preserving hippocampal neurogenesis? Neural Regen Res (2012) 0.78
Age-associated changes of nitric oxide concentration dynamics in the central nervous system of Fisher 344 rats. Cell Mol Neurobiol (2014) 0.76
Medial temporal lobe contributions to intra-item associative recognition memory in the aging brain. Front Behav Neurosci (2014) 0.76
Secrets of aging: What does a normally aging brain look like? F1000 Biol Rep (2011) 0.75
Motor Learning and Movement Performance: Older versus Younger Adults. Basic Clin Neurosci (2015) 0.75
Spatial pattern separation differences in older adult carriers and non-carriers for the apolipoprotein E epsilon 4 allele. Neurobiol Learn Mem (2015) 0.75
Rapamycin inhibits mTOR/p70S6K activation in CA3 region of the hippocampus of the rat and impairs long term memory. Neurobiol Learn Mem (2016) 0.75
Concerns with the use of T2* signal intensity to differentiate hippocampal subregions. Ann Neurol (2002) 0.75
Alterations in the Interplay between Neurons, Astrocytes and Microglia in the Rat Dentate Gyrus in Experimental Models of Neurodegeneration. Front Aging Neurosci (2017) 0.75
The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.26
Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.02
Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. Lancet Neurol (2007) 18.62
Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med (2012) 14.14
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet (2007) 9.80
Revising the definition of Alzheimer's disease: a new lexicon. Lancet Neurol (2010) 8.74
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
Apolipoprotein E, Alzheimer disease, and African Americans. Arch Neurol (2003) 4.63
Mediterranean diet and risk for Alzheimer's disease. Ann Neurol (2006) 4.38
HIV-associated cognitive impairment before and after the advent of combination therapy. J Neurovirol (2002) 4.20
Epidemiology of Alzheimer disease. Nat Rev Neurol (2011) 4.13
Physical activity, diet, and risk of Alzheimer disease. JAMA (2009) 4.11
Food combination and Alzheimer disease risk: a protective diet. Arch Neurol (2010) 3.99
Reading level attenuates differences in neuropsychological test performance between African American and White elders. J Int Neuropsychol Soc (2002) 3.83
Hypertension and the risk of mild cognitive impairment. Arch Neurol (2007) 3.62
A summary risk score for the prediction of Alzheimer disease in elderly persons. Arch Neurol (2010) 3.52
Stroke and the risk of Alzheimer disease. Arch Neurol (2003) 3.49
Neuropsychological prediction of conversion to Alzheimer disease in patients with mild cognitive impairment. Arch Gen Psychiatry (2006) 3.44
Mediterranean diet and mild cognitive impairment. Arch Neurol (2009) 3.40
Frequency and course of mild cognitive impairment in a multiethnic community. Ann Neurol (2008) 3.39
Early discontinuation and non-adherence to adjuvant hormonal therapy are associated with increased mortality in women with breast cancer. Breast Cancer Res Treat (2010) 3.35
Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families. PLoS One (2012) 3.11
Delusions and hallucinations are associated with worse outcome in Alzheimer disease. Arch Neurol (2005) 3.10
Mediterranean diet, Alzheimer disease, and vascular mediation. Arch Neurol (2006) 2.98
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol (2010) 2.91
Alcohol intake and risk of dementia. J Am Geriatr Soc (2004) 2.90
Pilot association study of the beta-glucocerebrosidase N370S allele and Parkinson's disease in subjects of Jewish ethnicity. Mov Disord (2005) 2.88
Hyperinsulinemia and risk of Alzheimer disease. Neurology (2004) 2.87
Relation of diabetes to mild cognitive impairment. Arch Neurol (2007) 2.86
Atherosclerosis and AD: analysis of data from the US National Alzheimer's Coordinating Center. Neurology (2005) 2.76
Brain morphology in older African Americans, Caribbean Hispanics, and whites from northern Manhattan. Arch Neurol (2008) 2.69
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA (2013) 2.58
Acculturation, reading level, and neuropsychological test performance among African American elders. Appl Neuropsychol (2004) 2.55
Mediterranean diet and Alzheimer disease mortality. Neurology (2007) 2.45
Mediterranean diet and magnetic resonance imaging-assessed cerebrovascular disease. Ann Neurol (2011) 2.44
Implementing diagnostic criteria and estimating frequency of mild cognitive impairment in an urban community. Arch Neurol (2005) 2.39
Neuropsychological dysfunction in the absence of structural evidence for cerebral ischemia after uncomplicated carotid endarterectomy. Neurosurgery (2006) 2.33
Cognitive decline and literacy among ethnically diverse elders. J Geriatr Psychiatry Neurol (2005) 2.33
Caloric intake and the risk of Alzheimer disease. Arch Neurol (2002) 2.28
Literacy and memory decline among ethnically diverse elders. J Clin Exp Neuropsychol (2003) 2.27
Cognitive reserve and lifestyle. J Clin Exp Neuropsychol (2003) 2.27
Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants. PLoS Genet (2012) 2.23
The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort. Arch Neurol (2007) 2.21
Shorter telomeres are associated with mortality in those with APOE epsilon4 and dementia. Ann Neurol (2006) 2.21
Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. Ann Neurol (2012) 2.20
Antioxidant vitamin intake and risk of Alzheimer disease. Arch Neurol (2003) 2.20
Incidence and predictors of seizures in patients with Alzheimer's disease. Epilepsia (2006) 2.17
Predictors of cognitive dysfunction after subarachnoid hemorrhage. Stroke (2002) 2.13
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron (2013) 2.13
Relation of plasma lipids to Alzheimer disease and vascular dementia. Arch Neurol (2004) 2.09
Incidence of dementia after ischemic stroke: results of a longitudinal study. Stroke (2002) 2.08
Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08
Association of life activities with cerebral blood flow in Alzheimer disease: implications for the cognitive reserve hypothesis. Arch Neurol (2003) 2.08
Association of glucocerebrosidase mutations with dementia with lewy bodies. Arch Neurol (2009) 2.06
Validity of self-reported stroke in elderly African Americans, Caribbean Hispanics, and Whites. Arch Neurol (2009) 2.05
Cognitive reserve: implications for diagnosis and prevention of Alzheimer's disease. Curr Neurol Neurosci Rep (2004) 2.03
Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNA. Clin Cancer Res (2007) 2.02
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. PLoS Genet (2011) 2.02
SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk. Ann Neurol (2011) 2.01
Cardiovascular risk factors and Alzheimer's disease. Curr Atheroscler Rep (2004) 2.00
Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. Arch Neurol (2012) 1.97
An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection. Arch Neurol (2007) 1.94
Combining early markers strongly predicts conversion from mild cognitive impairment to Alzheimer's disease. Biol Psychiatry (2008) 1.93
The brain in the age of old: the hippocampal formation is targeted differentially by diseases of late life. Ann Neurol (2008) 1.92
Distinct pools of beta-amyloid in Alzheimer disease-affected brain: a clinicopathologic study. Arch Neurol (2008) 1.92
A controlled prospective study of neuropsychological dysfunction following carotid endarterectomy. Arch Neurol (2002) 1.91
Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset Alzheimer disease. Arch Neurol (2010) 1.91
Dietary factors and Alzheimer's disease. Lancet Neurol (2004) 1.90
Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clin Investig (Lond) (2012) 1.90
Measures of adiposity and dementia risk in elderly persons. Arch Neurol (2007) 1.88
Age-related changes in brain activation during a delayed item recognition task. Neurobiol Aging (2006) 1.87
Contribution of vascular risk factors to the progression in Alzheimer disease. Arch Neurol (2009) 1.86
White matter hyperintensities and subclinical infarction: associations with psychomotor speed and cognitive flexibility. Stroke (2008) 1.84
Peripheral Abeta subspecies as risk biomarkers of Alzheimer's disease. Proc Natl Acad Sci U S A (2008) 1.84
Structural brain alterations in schizophrenia following fetal exposure to the inflammatory cytokine interleukin-8. Schizophr Res (2010) 1.83
An event-related fMRI study of the neurobehavioral impact of sleep deprivation on performance of a delayed-match-to-sample task. Brain Res Cogn Brain Res (2004) 1.80
Long-term blood pressure fluctuation and cerebrovascular disease in an elderly cohort. Arch Neurol (2010) 1.80
Attenuated central nervous system infection in advanced HIV/AIDS with combination antiretroviral therapy. Arch Neurol (2004) 1.79
Epidemiology of Alzheimer disease. Cold Spring Harb Perspect Med (2012) 1.78
A new approach to spatial covariance modeling of functional brain imaging data: ordinal trend analysis. Neural Comput (2005) 1.78
Disparities in the recording of Parkinson's disease on death certificates. Mov Disord (2005) 1.75
Multivariate and univariate neuroimaging biomarkers of Alzheimer's disease. Neuroimage (2008) 1.74
Health and function of participants in the Long Life Family Study: A comparison with other cohorts. Aging (Albany NY) (2011) 1.74
An observational study of cognitive impairment in amyotrophic lateral sclerosis. Arch Neurol (2006) 1.73
Increased sympathetic and decreased parasympathetic cardiovascular modulation in normal humans with acute sleep deprivation. J Appl Physiol (1985) (2005) 1.73
Stroke and memory performance in elderly persons without dementia. Arch Neurol (2006) 1.65
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet (2012) 1.63
Cognitive reserve modulates functional brain responses during memory tasks: a PET study in healthy young and elderly subjects. Neuroimage (2003) 1.62
Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals. Arch Neurol (2010) 1.61
Meta-analysis of the association between variants in SORL1 and Alzheimer disease. Arch Neurol (2011) 1.59
Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proc Natl Acad Sci U S A (2013) 1.58