Published in Trends Neurosci on October 13, 2006
Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI) | NCT01044758
Pattern separation in the hippocampus. Trends Neurosci (2011) 3.21
Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment. Neuron (2012) 2.89
High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic Mild Cognitive Impairment. Neuroimage (2010) 2.62
Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults. Hippocampus (2010) 2.39
The episodic memory system: neurocircuitry and disorders. Neuropsychopharmacology (2010) 1.91
Age-related memory deficits linked to circuit-specific disruptions in the hippocampus. Proc Natl Acad Sci U S A (2011) 1.88
Individual differences in spatial pattern separation performance associated with healthy aging in humans. Learn Mem (2010) 1.77
Senescent synapses and hippocampal circuit dynamics. Trends Neurosci (2010) 1.58
Ultrahigh-resolution microstructural diffusion tensor imaging reveals perforant path degradation in aged humans in vivo. Proc Natl Acad Sci U S A (2010) 1.50
A task to assess behavioral pattern separation (BPS) in humans: Data from healthy aging and mild cognitive impairment. Neuropsychologia (2013) 1.48
Cognitive aging: a common decline of episodic recollection and spatial memory in rats. J Neurosci (2008) 1.43
Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment. Neuropsychopharmacology (2009) 1.39
IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase. PLoS One (2009) 1.28
Potential adaptive function for altered long-term potentiation mechanisms in aging hippocampus. J Neurosci (2008) 1.23
Dissecting the age-related decline on spatial learning and memory tasks in rodent models: N-methyl-D-aspartate receptors and voltage-dependent Ca2+ channels in senescent synaptic plasticity. Prog Neurobiol (2012) 1.19
Cognitive decline is associated with reduced reelin expression in the entorhinal cortex of aged rats. Cereb Cortex (2010) 1.14
Prominent hippocampal CA3 gene expression profile in neurocognitive aging. Neurobiol Aging (2009) 1.12
A look inside the diabetic brain: Contributors to diabetes-induced brain aging. Biochim Biophys Acta (2008) 1.12
Characterizing cognitive aging of spatial and contextual memory in animal models. Front Aging Neurosci (2012) 1.12
Acute neuroinflammation impairs context discrimination memory and disrupts pattern separation processes in hippocampus. J Neurosci (2014) 1.11
Selective GABA(A) α5 positive allosteric modulators improve cognitive function in aged rats with memory impairment. Neuropharmacology (2012) 1.10
Successful cognitive aging in rats: a role for mGluR5 glutamate receptors, homer 1 proteins and downstream signaling pathways. PLoS One (2012) 1.07
An animal model of amnesia that uses Receiver Operating Characteristics (ROC) analysis to distinguish recollection from familiarity deficits in recognition memory. Neuropsychologia (2009) 1.04
Hilar interneuron vulnerability distinguishes aged rats with memory impairment. J Comp Neurol (2013) 1.04
Spatial pattern separation in cognitively normal young and older adults. Hippocampus (2012) 1.02
Episodic memory on the path to Alzheimer's disease. Curr Opin Neurobiol (2011) 1.01
Individual differences in neurocognitive aging of the medial temporal lobe. Age (Dordr) (2006) 1.01
Hippocampal subfield volumes: age, vascular risk, and correlation with associative memory. Front Aging Neurosci (2011) 1.01
Navigational expertise may compromise anterograde associative memory. Neuropsychologia (2009) 1.00
Aging reduces total neuron number in the dorsal component of the rodent prefrontal cortex. J Comp Neurol (2012) 0.97
Perturbations of neural circuitry in aging, mild cognitive impairment, and Alzheimer's disease. Ageing Res Rev (2013) 0.95
Glutamate receptor-mediated restoration of experience-dependent place field expansion plasticity in aged rats. Behav Neurosci (2008) 0.94
Region-specific genetic alterations in the aging hippocampus: implications for cognitive aging. Front Aging Neurosci (2010) 0.92
The effect of interference on temporal order memory for random and fixed sequences in nondemented older adults. Learn Mem (2012) 0.92
Less efficient pattern separation may contribute to age-related spatial memory deficits. Front Aging Neurosci (2012) 0.90
Neurocognitive Aging and the Hippocampus across Species. Trends Neurosci (2015) 0.89
Restoration of calbindin after fetal hippocampal CA3 cell grafting into the injured hippocampus in a rat model of temporal lobe epilepsy. Hippocampus (2007) 0.89
Mindspan: lessons from rat models of neurocognitive aging. ILAR J (2011) 0.89
Increased functional connectivity within medial temporal lobe in mild cognitive impairment. Hippocampus (2012) 0.88
ROC in animals: uncovering the neural substrates of recollection and familiarity in episodic recognition memory. Conscious Cogn (2010) 0.88
Memory encoding and dopamine in the aging brain: a psychopharmacological neuroimaging study. Cereb Cortex (2009) 0.88
Hand grip strength and associated factors in non-institutionalised men and women 50 years and older in South Africa. BMC Res Notes (2014) 0.87
Synaptic strength and postsynaptically silent synapses through advanced aging in rat hippocampal CA1 pyramidal neurons. Neurobiol Aging (2008) 0.87
Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performance. Neuroimage Clin (2015) 0.87
The effects of aging in delay and trace human eyeblink conditioning. Psychol Aging (2010) 0.86
Integrity of mGluR-LTD in the associative/commissural inputs to CA3 correlates with successful aging in rats. J Neurosci (2013) 0.86
Altered dendritic integration in hippocampal granule cells of spatial learning-impaired aged rats. J Neurophysiol (2008) 0.86
Group 1 metabotropic glutamate receptor function and its regulation of learning and memory in the aging brain. Front Pharmacol (2012) 0.85
Behaviorally activated mRNA expression profiles produce signatures of learning and enhanced inhibition in aged rats with preserved memory. PLoS One (2013) 0.83
Transcription of the immediate-early gene Arc in CA1 of the hippocampus reveals activity differences along the proximodistal axis that are attenuated by advanced age. J Neurosci (2013) 0.83
Bridging neurocognitive aging and disease modification: targeting functional mechanisms of memory impairment. Curr Alzheimer Res (2010) 0.83
Olfactory memory: a bridge between humans and animals in models of cognitive aging. Ann N Y Acad Sci (2009) 0.81
Increased learning and brain long-term potentiation in aged mice lacking DNA polymerase μ. PLoS One (2013) 0.81
Age-related changes in place learning for adjacent and separate locations. Neurobiol Aging (2013) 0.81
Visual object pattern separation varies in older adults. Learn Mem (2013) 0.81
Perceptual versus conceptual interference and pattern separation of verbal stimuli in young and older adults. Hippocampus (2013) 0.81
Synaptic commitment: developmentally regulated reciprocal changes in hippocampal granule cell NMDA and AMPA receptors over the lifespan. J Neurophysiol (2008) 0.81
Targeting Adult Neurogenesis to Optimize Hippocampal Circuits in Aging. Neurotherapeutics (2017) 0.80
Spatial pattern completion deficits in older adults. Front Aging Neurosci (2013) 0.80
Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression. J Neurosci (2015) 0.80
Targeting Neural Hyperactivity as a Treatment to Stem Progression of Late-Onset Alzheimer's Disease. Neurotherapeutics (2017) 0.80
Cognitive deficits caused by prefrontal cortical and hippocampal neural disinhibition. Br J Pharmacol (2017) 0.79
Age-related declines in the fidelity of newly acquired category representations. Learn Mem (2012) 0.78
The effect of navigational expertise on wayfinding in new environments. J Environ Psychol (2010) 0.78
Differences in temporal order memory among young, middle-aged, and older adults may depend on the level of interference. Front Aging Neurosci (2015) 0.78
Memory for sequences of events impaired in typical aging. Learn Mem (2015) 0.78
False memories with age: Neural and cognitive underpinnings. Neuropsychologia (2016) 0.78
Changes in pattern completion--a key mechanism to explain age-related recognition memory deficits? Cortex (2014) 0.77
Age-related impairments on one hippocampal-dependent task predict impairments on a subsequent hippocampal-dependent task. Behav Neurosci (2014) 0.77
Chronic Ampakine Treatments Stimulate Dendritic Growth and Promote Learning in Middle-Aged Rats. J Neurosci (2016) 0.77
Combined administration of levetiracetam and valproic acid attenuates age-related hyperactivity of CA3 place cells, reduces place field area, and increases spatial information content in aged rat hippocampus. Hippocampus (2015) 0.77
Age-related Changes in Lateral Entorhinal and CA3 Neuron Allocation Predict Poor Performance on Object Discrimination. Front Syst Neurosci (2017) 0.76
Age-related increases in false recognition: the role of perceptual and conceptual similarity. Front Aging Neurosci (2014) 0.76
Experience-dependent persistent expression of zif268 during rest is preserved in the aged dentate gyrus. BMC Neurosci (2013) 0.76
Type 3 Adenylyl Cyclase and Somatostatin Receptor 3 Expression Persists in Aged Rat Neocortical and Hippocampal Neuronal Cilia. Front Aging Neurosci (2016) 0.76
Age-associated changes in the hippocampal-ventral striatum-ventral tegmental loop that impact learning, prediction, and context discrimination. Front Aging Neurosci (2012) 0.76
Dopamine and memory dedifferentiation in aging. Neuroimage (2015) 0.76
Stability of age-related deficits in the mnemonic similarity task across task variations. Behav Neurosci (2015) 0.76
Time-place learning over a lifetime: absence of memory loss in trained old mice. Learn Mem (2015) 0.76
Regional-specific effects of ovarian hormone loss on synaptic plasticity in adult human APOE targeted replacement mice. PLoS One (2014) 0.76
Selective vulnerabilities and biomarkers in neurocognitive aging. F1000Res (2017) 0.75
Heightened cortical excitability in aged rodents with memory impairment. Neurobiol Aging (2017) 0.75
Self-rated health and associated factors among older South Africans: evidence from the study on global ageing and adult health. Glob Health Action (2013) 0.75
From Engrams to Pathologies of the Brain. Front Neural Circuits (2017) 0.75
Age-related changes in detection of spatial novelty. Behav Brain Res (2011) 0.75
Rodent age-related impairments in discriminating perceptually similar objects parallel those observed in humans. Hippocampus (2017) 0.75
Activating Developmental Reserve Capacity Via Cognitive Training or Non-invasive Brain Stimulation: Potentials for Promoting Fronto-Parietal and Hippocampal-Striatal Network Functions in Old Age. Front Aging Neurosci (2017) 0.75
Age differences in hippocampal activation during gist-based false recognition. Neurobiol Aging (2016) 0.75
3T hippocampal glutamate-glutamine complex reflects verbal memory decline in aging. Neurobiol Aging (2017) 0.75
Functional connectivity with the retrosplenial cortex predicts cognitive aging in rats. Proc Natl Acad Sci U S A (2016) 0.75
Increased hippocampal activation in ApoE-4 carriers and non-carriers with amnestic mild cognitive impairment. Neuroimage Clin (2016) 0.75
Novel word learning in older adults: A role for sleep? Brain Lang (2016) 0.75
Physiological and anatomical studies of associative learning: Convergence with learning studies of W.T. Greenough. Dev Psychobiol (2011) 0.75
Aerobic fitness associates with mnemonic discrimination as a mediator of physical activity effects: evidence for memory flexibility in young adults. Sci Rep (2017) 0.75
Dynamics of the hippocampal ensemble code for space. Science (1993) 9.47
Insights into the ageing mind: a view from cognitive neuroscience. Nat Rev Neurosci (2004) 6.62
The hippocampal-VTA loop: controlling the entry of information into long-term memory. Neuron (2005) 6.33
Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet (1976) 6.09
Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J Comp Physiol Psychol (1979) 6.07
Hippocampus: cognitive processes and neural representations that underlie declarative memory. Neuron (2004) 5.15
Independent codes for spatial and episodic memory in hippocampal neuronal ensembles. Science (2005) 4.86
Distinct ensemble codes in hippocampal areas CA3 and CA1. Science (2004) 4.82
Neural plasticity in the ageing brain. Nat Rev Neurosci (2006) 4.66
Hippocampal neurons encode information about different types of memory episodes occurring in the same location. Neuron (2000) 4.44
The hippocampus, memory, and place cells: is it spatial memory or a memory space? Neuron (1999) 4.36
Path integration and cognitive mapping in a continuous attractor neural network model. J Neurosci (1997) 3.69
Trajectory encoding in the hippocampus and entorhinal cortex. Neuron (2000) 3.48
Prospective and retrospective memory coding in the hippocampus. Neuron (2003) 3.42
Imaging hippocampal function across the human life span: is memory decline normal or not? Ann Neurol (2002) 3.34
Aging, sexual dimorphism, and hemispheric asymmetry of the cerebral cortex: replicability of regional differences in volume. Neurobiol Aging (2004) 3.18
Feature memory and binding in young and older adults. Mem Cognit (1996) 3.13
Place cells and place recognition maintained by direct entorhinal-hippocampal circuitry. Science (2002) 3.13
Comparison of population coherence of place cells in hippocampal subfields CA1 and CA3. Nature (2004) 3.06
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment. Neurobiol Aging (2005) 2.97
No loss of synaptic proteins in the hippocampus of aged, behaviorally impaired rats. Neurobiol Aging (2000) 2.96
Neural mechanisms for detecting and remembering novel events. Nat Rev Neurosci (2003) 2.95
Deciphering the hippocampal polyglot: the hippocampus as a path integration system. J Exp Biol (1996) 2.86
Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog Neurobiol (2003) 2.85
Experience-dependent, asymmetric expansion of hippocampal place fields. Proc Natl Acad Sci U S A (1997) 2.68
Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats. J Neurosci (2000) 2.51
Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging. Proc Natl Acad Sci U S A (2004) 2.39
The use of animal models to study the effects of aging on cognition. Annu Rev Psychol (1997) 2.32
Dynamics of learning and recall at excitatory recurrent synapses and cholinergic modulation in rat hippocampal region CA3. J Neurosci (1995) 2.14
Storage, recall, and novelty detection of sequences by the hippocampus: elaborating on the SOCRATIC model to account for normal and aberrant effects of dopamine. Hippocampus (2001) 2.13
Ensemble dynamics of hippocampal regions CA3 and CA1. Neuron (2004) 2.02
Age-related loss of axospinous synapses formed by two afferent systems in the rat dentate gyrus as revealed by the unbiased stereological dissector technique. Hippocampus (1992) 1.85
Age-associated alterations of hippocampal place cells are subregion specific. J Neurosci (2005) 1.82
Laminar selectivity of the cholinergic suppression of synaptic transmission in rat hippocampal region CA1: computational modeling and brain slice physiology. J Neurosci (1994) 1.81
Hippocampal network hyperactivity after selective reduction of tonic inhibition in GABA A receptor alpha5 subunit-deficient mice. J Neurophysiol (2006) 1.74
Cognitive maps beyond the hippocampus. Hippocampus (1997) 1.73
Age-related dopamine D2/D3 receptor loss in extrastriatal regions of the human brain. Neurobiol Aging (2000) 1.71
NMDA receptor antagonism blocks experience-dependent expansion of hippocampal "place fields". Neuron (2001) 1.67
NMDA receptor-independent long-term depression correlates with successful aging in rats. Nat Neurosci (2005) 1.65
Multistability of cognitive maps in the hippocampus of old rats. Nature (1997) 1.65
Free recall and recognition in a network model of the hippocampus: simulating effects of scopolamine on human memory function. Behav Brain Res (1997) 1.63
Considerations arising from a complementary learning systems perspective on hippocampus and neocortex. Hippocampus (1996) 1.63
Increased susceptibility to induction of long-term depression and long-term potentiation reversal during aging. J Neurosci (1996) 1.58
Age-related differences in novelty and target processing among cognitively high performing adults. Neurobiol Aging (2004) 1.55
Reduction in size of perforated postsynaptic densities in hippocampal axospinous synapses and age-related spatial learning impairments. J Neurosci (2004) 1.50
Aging and source monitoring: cognitive processes and neuropsychological correlates. J Exp Psychol Gen (1998) 1.43
Normal aging: regionally specific changes in hippocampal synaptic transmission. Trends Neurosci (1994) 1.42
Preserved spatial coding in hippocampal CA1 pyramidal cells during reversible suppression of CA3c output: evidence for pattern completion in hippocampus. J Neurosci (1989) 1.39
Involvement of hippocampal synaptic plasticity in age-related memory decline. Brain Res Brain Res Rev (1999) 1.35
Memory, language, and ageing. Philos Trans R Soc Lond B Biol Sci (1997) 1.33
Age-related differences in an ecologically based study of route learning. Psychol Aging (1997) 1.31
Aging, spatial learning, and total synapse number in the rat CA1 stratum radiatum. Neurobiol Aging (2004) 1.29
Place cell rigidity correlates with impaired spatial learning in aged rats. Neurobiol Aging (2002) 1.28
Dopamine selectively inhibits the direct cortical pathway to the CA1 hippocampal region. J Neurosci (1999) 1.25
The effect of aging on experience-dependent plasticity of hippocampal place cells. J Neurosci (1997) 1.22
Cognitive aging and the hippocampus: how old rats represent new environments. J Neurosci (2004) 1.17
Examining the gateway to the limbic system with diffusion tensor imaging: the perforant pathway in dementia. Neuroimage (2005) 1.16
The relationship of age to prepulse inhibition and habituation of the acoustic startle response. Biol Psychol (2003) 1.15
Cell death or synaptic loss in Alzheimer disease. J Neuropathol Exp Neurol (2000) 1.15
LTP induction threshold change in old rats at the perforant path--granule cell synapse. Neurobiol Aging (2000) 1.14
Aging in the rat hippocampus is associated with widespread reductions in the number of glutamate decarboxylase-67 positive interneurons but not interneuron degeneration. J Neurochem (2004) 1.14
Role of temporal summation in age-related long-term potentiation-induction deficits. Hippocampus (1997) 1.13
Septo-hippocampal cholinergic and neurotrophin markers in age-induced cognitive decline. Neurobiol Aging (1998) 1.08
Episodic spatial memory in adulthood. Psychol Aging (1993) 1.08
On the number of neurons in the dentate gyrus of the rat. Brain Res (1985) 1.07
NGF improves spatial memory in aged rodents as a function of age. J Neurosci (1991) 1.06
Metabotropic glutamate receptor-mediated hippocampal phosphoinositide turnover is blunted in spatial learning-impaired aged rats. J Neurosci (1999) 1.06
Rat hippocampal GABAergic molecular markers are differentially affected by ageing. J Neurochem (2003) 1.04
Brain aging: impaired coding of novel environmental cues. J Neurosci (1997) 1.03
Decreased plasma membrane expression of striatal dopamine transporter in aging. Neurobiol Aging (2003) 1.03
Stereological quantification of GAD-67-immunoreactive neurons and boutons in the hippocampus of middle-aged and old Fischer 344 x Brown Norway rats. J Comp Neurol (2004) 1.02
Age-related biophysical alterations of hippocampal pyramidal neurons: implications for learning and memory. Ageing Res Rev (2002) 0.99
Age-related decrease in cholinergic synaptic transmission in three hippocampal subfields. Neurobiol Aging (1996) 0.99
Immunohistochemical and neurochemical correlates of learning deficits in aged rats. Neuroscience (2000) 0.97
Aging impairs the late phase of long-term potentiation at the medial perforant path-CA3 synapse in awake rats. Synapse (2004) 0.96
Degenerative Changes in Forebrain Cholinergic Nuclei Correlate with Cognitive Impairments in Aged Rats. Eur J Neurosci (1989) 0.96
Spatial cognition and behavior in young and elderly adults: implications for learning new environments. Psychol Aging (1991) 0.95
Age-related deficits in the ability to encode contextual change: a place cell analysis. Hippocampus (2000) 0.94
Neuron-specific age-related decreases in dopamine receptor subtype mRNAs. J Comp Neurol (2003) 0.94
Hilar neuropeptide Y interneuron loss in the aged rat hippocampal formation. Exp Neurol (2003) 0.93
The hippocampal debate: are we asking the right questions? Behav Brain Res (2001) 0.93
Spatial memory deficits in aged rats: contributions of the cholinergic system assessed by ChAT. Brain Res (1990) 0.92
Reconciling Barnes et al. (1997) and Tanila et al. (1997a,b). Hippocampus (1998) 0.90
Event-related brain potential investigations of memory and aging. Biol Psychol (2000) 0.90
Convergent cholinergic activities in aging and Alzheimer's disease. Neurobiol Aging (1992) 0.89
Markers for biogenic amines in the aged rat brain: relationship to decline in spatial learning ability. Neurobiol Aging (1990) 0.89
Data-driven recognition memory: a new technique and some data on age differences. Psychon Bull Rev (2001) 0.88
Age-related neuronal loss from the substantia nigra-pars compacta and ventral tegmental area of the rhesus monkey. J Neuropathol Exp Neurol (1999) 0.87
Hippocampal muscarinic receptor function in spatial learning-impaired aged rats. Neurobiol Aging (1996) 0.86
Modulation of cholinergic transmission enhances excitability of hippocampal pyramidal neurons and ameliorates learning impairments in aging animals. Neurobiol Learn Mem (2003) 0.86
Cholinergic cell loss and hypertrophy in the medial septal nucleus of the behaviorally characterized aged rhesus monkey. J Neurosci (1992) 0.85
Elderly men and women are less responsive to startling noises: N1, P3 and blink evidence. Biol Psychol (1995) 0.84
Age-sensitivity of P3 in high-functioning adults. Neurobiol Aging (2005) 0.82
Visualization of muscarinic receptor-mediated phosphoinositide turnover in the hippocampus of young and aged, learning-impaired Long Evans rats. Hippocampus (2001) 0.81
A specific amyloid-beta protein assembly in the brain impairs memory. Nature (2006) 16.19
Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory. Cell (2003) 4.58
Encoding predicted outcome and acquired value in orbitofrontal cortex during cue sampling depends upon input from basolateral amygdala. Neuron (2003) 4.53
Hippocampal "time cells" bridge the gap in memory for discontiguous events. Neuron (2011) 3.92
Different roles for orbitofrontal cortex and basolateral amygdala in a reinforcer devaluation task. J Neurosci (2003) 3.51
Recollection-like memory retrieval in rats is dependent on the hippocampus. Nature (2004) 3.37
Theta-gamma coupling increases during the learning of item-context associations. Proc Natl Acad Sci U S A (2009) 3.17
Robust conjunctive item-place coding by hippocampal neurons parallels learning what happens where. J Neurosci (2009) 3.05
Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proc Natl Acad Sci U S A (2007) 3.02
Measuring phase-amplitude coupling between neuronal oscillations of different frequencies. J Neurophysiol (2010) 3.00
Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment. Neuron (2012) 2.89
Gradual changes in hippocampal activity support remembering the order of events. Neuron (2007) 2.85
Amygdala-frontal interactions and reward expectancy. Curr Opin Neurobiol (2004) 2.83
High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic Mild Cognitive Impairment. Neuroimage (2010) 2.62
Lesions of orbitofrontal cortex and basolateral amygdala complex disrupt acquisition of odor-guided discriminations and reversals. Learn Mem (2003) 2.56
Rapid associative encoding in basolateral amygdala depends on connections with orbitofrontal cortex. Neuron (2005) 2.52
Neural encoding in ventral striatum during olfactory discrimination learning. Neuron (2003) 2.42
Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults. Hippocampus (2010) 2.39
Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy. J Neurosci (2009) 2.33
Amygdalar and prefrontal pathways to the lateral hypothalamus are activated by a learned cue that stimulates eating. J Neurosci (2005) 2.32
Hippocampal "time cells": time versus path integration. Neuron (2013) 2.23
Double dissociation of the effects of lesions of basolateral and central amygdala on conditioned stimulus-potentiated feeding and Pavlovian-instrumental transfer. Eur J Neurosci (2003) 2.19
Evolution of declarative memory. Hippocampus (2006) 2.15
Hippocampal mechanisms for the context-dependent retrieval of episodes. Neural Netw (2005) 1.93
A cognitive map for object memory in the hippocampus. Learn Mem (2009) 1.92
The episodic memory system: neurocircuitry and disorders. Neuropsychopharmacology (2010) 1.91
Interplay of hippocampus and prefrontal cortex in memory. Curr Biol (2013) 1.90
Age-associated alterations of hippocampal place cells are subregion specific. J Neurosci (2005) 1.82
The hippocampus and disambiguation of overlapping sequences. J Neurosci (2002) 1.81
Increased fMRI responses during encoding in mild cognitive impairment. Neurobiol Aging (2006) 1.74
Role of alpha-synuclein in presynaptic dopamine recruitment. J Neurosci (2004) 1.74
Disconnection of the basolateral amygdala complex and nucleus accumbens impairs appetitive pavlovian second-order conditioned responses. Behav Neurosci (2002) 1.74
Amygdalo-hypothalamic circuit allows learned cues to override satiety and promote eating. J Neurosci (2002) 1.69
Orbitofrontal lesions impair use of cue-outcome associations in a devaluation task. Behav Neurosci (2005) 1.65
NMDA receptor-independent long-term depression correlates with successful aging in rats. Nat Neurosci (2005) 1.65
Transitive inference in schizophrenia: impairments in relational memory organization. Schizophr Res (2004) 1.64
Visual presentation of novel objects and new spatial arrangements of objects differentially activates the medial temporal lobe subareas in humans. Eur J Neurosci (2004) 1.63
Role of amygdalo-nigral circuitry in conditioning of a visual stimulus paired with food. J Neurosci (2005) 1.61
The hippocampus and memory for "what," "where," and "when". Learn Mem (2004) 1.59
The basolateral amygdala is critical to the expression of pavlovian and instrumental outcome-specific reinforcer devaluation effects. J Neurosci (2009) 1.56
Entorhinal cortex lesions disrupt the relational organization of memory in monkeys. J Neurosci (2004) 1.55
Recognition memory: opposite effects of hippocampal damage on recollection and familiarity. Nat Neurosci (2007) 1.53
Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease. J Neurochem (2013) 1.51
The basolateral complex of the amygdala is necessary for acquisition but not expression of CS motivational value in appetitive Pavlovian second-order conditioning. Eur J Neurosci (2002) 1.50
Reduction in size of perforated postsynaptic densities in hippocampal axospinous synapses and age-related spatial learning impairments. J Neurosci (2004) 1.50
Gradual translocation of spatial correlates of neuronal firing in the hippocampus toward prospective reward locations. Neuron (2006) 1.49
Gender differences in the amount and deposition of amyloidbeta in APPswe and PS1 double transgenic mice. Neurobiol Dis (2003) 1.48
The effects of amygdala lesions on conditioned stimulus-potentiated eating in rats. Physiol Behav (2002) 1.46
Selective immunotoxic lesions of basal forebrain cholinergic cells: effects on learning and memory in rats. Behav Neurosci (2013) 1.44
The role of CA3 hippocampal NMDA receptors in paired associate learning. J Neurosci (2006) 1.44
Cognitive aging: a common decline of episodic recollection and spatial memory in rats. J Neurosci (2008) 1.43
Teaching old rats new tricks: age-related impairments in olfactory reversal learning. Neurobiol Aging (2002) 1.43
Striatal versus hippocampal representations during win-stay maze performance. J Neurophysiol (2009) 1.40
Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment. Neuropsychopharmacology (2009) 1.39
Encoding changes in orbitofrontal cortex in reversal-impaired aged rats. J Neurophysiol (2005) 1.38
Consolidation and reconsolidation: two lives of memories? Neuron (2011) 1.37
Learned contextual cue potentiates eating in rats. Physiol Behav (2006) 1.37
Lesions of orbitofrontal cortex impair rats' differential outcome expectancy learning but not conditioned stimulus-potentiated feeding. J Neurosci (2005) 1.36
Spatial representations of hippocampal CA1 neurons are modulated by behavioral context in a hippocampus-dependent memory task. J Neurosci (2007) 1.35
Orexin loss in Huntington's disease. Hum Mol Genet (2004) 1.33
Distinct roles for dorsal CA3 and CA1 in memory for sequential nonspatial events. Learn Mem (2009) 1.32
Dynamics of hippocampal and cortical activation during consolidation of a nonspatial memory. J Neurosci (2006) 1.32
Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A (2009) 1.31
Flexible polyimide microelectrode array for in vivo recordings and current source density analysis. Biosens Bioelectron (2006) 1.28
Pyrrolidine dithiocarbamate activates Akt and improves spatial learning in APP/PS1 mice without affecting beta-amyloid burden. J Neurosci (2007) 1.28
Multiple receptors coupled to phospholipase C gate long-term depression in visual cortex. J Neurosci (2005) 1.28
Medial prefrontal cortex is necessary for an appetitive contextual conditioned stimulus to promote eating in sated rats. J Neurosci (2007) 1.27
Different roles for amygdala central nucleus and substantia innominata in the surprise-induced enhancement of learning. J Neurosci (2006) 1.27
Disambiguation of overlapping experiences by neurons in the medial entorhinal cortex. J Neurosci (2007) 1.25
Central, but not basolateral, amygdala is critical for control of feeding by aversive learned cues. J Neurosci (2009) 1.24
Memory for the order of events in specific sequences: contributions of the hippocampus and medial prefrontal cortex. J Neurosci (2011) 1.24
Potential adaptive function for altered long-term potentiation mechanisms in aging hippocampus. J Neurosci (2008) 1.23
Medial prefrontal cortex supports recollection, but not familiarity, in the rat. J Neurosci (2008) 1.23
Vasopressin 1b receptor knock-out impairs memory for temporal order. J Neurosci (2009) 1.22
Hippocampal CA1 spiking during encoding and retrieval: relation to theta phase. Neurobiol Learn Mem (2006) 1.21
Distinct hippocampal time cell sequences represent odor memories in immobilized rats. J Neurosci (2013) 1.21
Genetic background differences and nonassociative effects in mouse trace fear conditioning. Learn Mem (2007) 1.20
Ventral hippocampal neurons are shaped by experience to represent behaviorally relevant contexts. J Neurosci (2013) 1.19
Rat orbitofrontal cortex separately encodes response and outcome information during performance of goal-directed behavior. J Neurosci (2008) 1.19
Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's disease. J Neuroinflammation (2010) 1.18
Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness. Proc Natl Acad Sci U S A (2013) 1.18
Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease. J Pharmacol Exp Ther (2004) 1.17
Longitudinal observation on CSF Abeta42 levels in young to middle-aged amyloid precursor protein/presenilin-1 doubly transgenic mice. Neurobiol Dis (2004) 1.17
Cognitive aging and the hippocampus: how old rats represent new environments. J Neurosci (2004) 1.17
Role of substantia nigra-amygdala connections in surprise-induced enhancement of attention. J Neurosci (2006) 1.17
Non-fibrillar beta-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors. Eur J Neurosci (2006) 1.15
Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients. Neurobiol Aging (2007) 1.15
Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein. Neurobiol Dis (2005) 1.15
Cognitive decline is associated with reduced reelin expression in the entorhinal cortex of aged rats. Cereb Cortex (2010) 1.14
Cortical glutamate-dopamine interaction and ketamine-induced psychotic symptoms in man. Psychopharmacology (Berl) (2005) 1.14
Associatively learned representations of taste outcomes activate taste-encoding neural ensembles in gustatory cortex. J Neurosci (2009) 1.14
Cholinergic deafferentation of the entorhinal cortex in rats impairs encoding of novel but not familiar stimuli in a delayed nonmatch-to-sample task. J Neurosci (2005) 1.14
Distinct contributions of the hippocampus and medial prefrontal cortex to the "what-where-when" components of episodic-like memory in mice. Behav Brain Res (2009) 1.14
Prominent hippocampal CA3 gene expression profile in neurocognitive aging. Neurobiol Aging (2009) 1.12
Distinct pathways for rule-based retrieval and spatial mapping of memory representations in hippocampal neurons. J Neurosci (2013) 1.12