Published in J Biol Chem on March 20, 2002
Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP. Mol Cell Biol (2003) 1.44
Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP. Mol Cell Biol (2005) 1.41
Conformation-sensing antibodies stabilize the oxidized form of PTP1B and inhibit its phosphatase activity. Cell (2011) 1.34
Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase. J Biol Chem (2008) 1.15
T-cell protein tyrosine phosphatase attenuates STAT3 and insulin signaling in the liver to regulate gluconeogenesis. Diabetes (2010) 1.03
Site-specific incorporation of allosteric-inhibition sites in a protein tyrosine phosphatase. J Am Chem Soc (2007) 0.97
Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis. Biochem J (2004) 0.86
TC-PTP directly interacts with connexin43 to regulate gap junction intercellular communication. J Cell Sci (2014) 0.83
The use of phage display to generate conformation-sensor recombinant antibodies. Nat Protoc (2012) 0.82
T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice. Diabetologia (2011) 0.82
Molecular dynamics simulation study of PTP1B with allosteric inhibitor and its application in receptor based pharmacophore modeling. J Comput Aided Mol Des (2008) 0.80
Target-specific control of lymphoid-specific protein tyrosine phosphatase (Lyp) activity. Bioorg Med Chem (2010) 0.80
Protein tyrosine phosphatases and type 1 diabetes: genetic and functional implications of PTPN2 and PTPN22. Rev Diabet Stud (2012) 0.80
The nucleus- and endoplasmic reticulum-targeted forms of protein tyrosine phosphatase 61F regulate Drosophila growth, life span, and fecundity. Mol Cell Biol (2013) 0.80
Wedelolactone, a naturally occurring coumestan, enhances interferon-γ signaling through inhibiting STAT1 protein dephosphorylation. J Biol Chem (2013) 0.79
Identification of Bidentate Salicylic Acid Inhibitors of PTP1B. ACS Med Chem Lett (2015) 0.76
Selective binding modes and allosteric inhibitory effects of lupane triterpenes on protein tyrosine phosphatase 1B. Sci Rep (2016) 0.75
Virtual screening, optimization, and identification of a novel specific PTP-MEG2 Inhibitor with potential therapy for T2DM. Oncotarget (2016) 0.75
Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog. Nat Struct Biol (2003) 2.56
An open-label, two-arm, phase I trial of recombinant human interleukin-21 in patients with metastatic melanoma. Clin Cancer Res (2007) 1.38
Characterization of recombinant murine factor VIIa and recombinant murine tissue factor: a human-murine species compatibility study. Thromb Res (2004) 1.18
Simulations of a membrane-anchored peptide: structure, dynamics, and influence on bilayer properties. Biophys J (2004) 1.04
Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B. J Med Chem (2002) 0.99
Tyrosine 547 constitutes an essential part of the catalytic mechanism of dipeptidyl peptidase IV. J Biol Chem (2004) 0.93
Novel tricyclic-alpha-alkyloxyphenylpropionic acids: dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity. J Med Chem (2002) 0.91
Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV. Biochem J (2006) 0.90
Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor alpha/gamma agonist ragaglitazar. J Med Chem (2003) 0.87
A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2beta). Biochem J (2003) 0.86
Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis. Biochem J (2004) 0.86
Enzyme kinetic characterization of protein tyrosine phosphatases. Biochimie (2003) 0.83
Structure-based design of selective and potent inhibitors of protein-tyrosine phosphatase beta. J Biol Chem (2004) 0.83
Design and synthesis of novel PPARalpha/gamma/delta triple activators using a known PPARalpha/gamma dual activator as structural template. Bioorg Med Chem Lett (2003) 0.75
Affinity purification of recombinant protein-tyrosine phosphatase 1B using a highly selective inhibitor. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.75