Published in Mol Microbiol on March 01, 2002
Role of innate immunity in Helicobacter pylori-induced gastric malignancy. Physiol Rev (2010) 1.73
Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain. Proc Natl Acad Sci U S A (2007) 1.46
Interactions between bacterial pathogens and mitochondrial cell death pathways. Nat Rev Microbiol (2010) 1.30
Helicobacter pylori VacA toxin promotes bacterial intracellular survival in gastric epithelial cells. Infect Immun (2006) 1.16
A Tale of Two Toxins: Helicobacter Pylori CagA and VacA Modulate Host Pathways that Impact Disease. Front Microbiol (2010) 1.00
Remodeling the host environment: modulation of the gastric epithelium by the Helicobacter pylori vacuolating toxin (VacA). Front Cell Infect Microbiol (2012) 0.96
Fluorescence resonance energy transfer microscopy of the Helicobacter pylori vacuolating cytotoxin within mammalian cells. Infect Immun (2002) 0.92
Helicobacter pylori VacA subdomain required for intracellular toxin activity and assembly of functional oligomeric complexes. Infect Immun (2008) 0.92
Reconstitution of Helicobacter pylori VacA toxin from purified components. Biochemistry (2010) 0.87
Expression of Helicobacter pylori vacuolating toxin in Escherichia coli. Infect Immun (2003) 0.87
the versatility of the Helicobacter pylori vacuolating cytotoxin vacA in signal transduction and molecular crosstalk. Toxins (Basel) (2010) 0.86
The intermediate region of Helicobacter pylori VacA is a determinant of toxin potency in a Jurkat T cell assay. Infect Immun (2012) 0.86
An Overview of Helicobacter pylori VacA Toxin Biology. Toxins (Basel) (2016) 0.81
Analysis of a beta-helical region in the p55 domain of Helicobacter pylori vacuolating toxin. BMC Microbiol (2010) 0.81
Mapping of a domain required for protein-protein interactions and inhibitory activity of a Helicobacter pylori dominant-negative VacA mutant protein. Infect Immun (2006) 0.81
Random mutagenesis of Helicobacter pylori vacA to identify amino acids essential for vacuolating cytotoxic activity. Infect Immun (2006) 0.81
A Nonoligomerizing Mutant Form of Helicobacter pylori VacA Allows Structural Analysis of the p33 Domain. Infect Immun (2016) 0.76
Helicobacter pylori VacA, a paradigm for toxin multifunctionality. Nat Rev Microbiol (2005) 3.25
Helicobacter pylori CagA activates NF-kappaB by targeting TAK1 for TRAF6-mediated Lys 63 ubiquitination. EMBO Rep (2009) 1.63
Adaptation of aerobic respiration to low O2 environments. Proc Natl Acad Sci U S A (2011) 1.63
Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses. Proc Natl Acad Sci U S A (2013) 1.60
Heterogeneity of vaginal microbial communities within individuals. J Clin Microbiol (2009) 1.50
Effect of Helicobacter pylori's vacuolating cytotoxin on the autophagy pathway in gastric epithelial cells. Autophagy (2009) 1.45
Helicobacter pylori vacuolating cytotoxin enters cells, localizes to the mitochondria, and induces mitochondrial membrane permeability changes correlated to toxin channel activity. Cell Microbiol (2004) 1.36
Plasma membrane cholesterol modulates cellular vacuolation induced by the Helicobacter pylori vacuolating cytotoxin. Infect Immun (2002) 1.20
Transition State Structure for the Hydrolysis of NAD Catalyzed by Diphtheria Toxin. J Am Chem Soc (1997) 1.20
Cellular vacuolation and mitochondrial cytochrome c release are independent outcomes of Helicobacter pylori vacuolating cytotoxin activity that are each dependent on membrane channel formation. J Biol Chem (2003) 1.18
Sphingomyelin functions as a novel receptor for Helicobacter pylori VacA. PLoS Pathog (2008) 1.13
Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans. Gastroenterology (2012) 1.12
Effects of endogenous D-alanine synthesis and autoinhibition of Bacillus anthracis germination on in vitro and in vivo infections. Infect Immun (2007) 1.11
Inhibition of Bacillus anthracis spore outgrowth by nisin. Antimicrob Agents Chemother (2008) 1.08
Helicobacter pylori vacuolating cytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death. Proc Natl Acad Sci U S A (2011) 1.08
Cytolethal distending toxin family members are differentially affected by alterations in host glycans and membrane cholesterol. J Biol Chem (2010) 1.06
Mechanism of inhibition of Bacillus anthracis spore outgrowth by the lantibiotic nisin. ACS Chem Biol (2011) 1.06
Order-disorder-order transitions mediate the activation of cholera toxin. J Mol Biol (2008) 0.99
Remodeling the host environment: modulation of the gastric epithelium by the Helicobacter pylori vacuolating toxin (VacA). Front Cell Infect Microbiol (2012) 0.96
Fluorescence resonance energy transfer microscopy of the Helicobacter pylori vacuolating cytotoxin within mammalian cells. Infect Immun (2002) 0.92
Membrane interaction of Pasteurella multocida toxin involves sphingomyelin. FEBS J (2011) 0.92
Functional comparison of the two Bacillus anthracis glutamate racemases. J Bacteriol (2007) 0.92
Bacterial toxin modulation of the eukaryotic cell cycle: are all cytolethal distending toxins created equally? Front Cell Infect Microbiol (2012) 0.92
Helicobacter pylori VacA subdomain required for intracellular toxin activity and assembly of functional oligomeric complexes. Infect Immun (2008) 0.92
Determinants of catalytic power and ligand binding in glutamate racemase. J Am Chem Soc (2009) 0.91
Characterization of a cytotoxic factor in culture filtrates of Serratia marcescens. Infect Immun (2002) 0.89
Bacillus anthracis spore interactions with mammalian cells: relationship between germination state and the outcome of in vitro. BMC Microbiol (2011) 0.88
High-throughput, single-cell analysis of macrophage interactions with fluorescently labeled Bacillus anthracis spores. Appl Environ Microbiol (2008) 0.87
Sphingomyelin is important for the cellular entry and intracellular localization of Helicobacter pylori VacA. Cell Microbiol (2010) 0.86
Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori. Proc Natl Acad Sci U S A (2009) 0.84
Cellular interactions of the cytolethal distending toxins from Escherichia coli and Haemophilus ducreyi. J Biol Chem (2013) 0.84
Exploiting Enzyme Plasticity in Virtual Screening: High Efficiency Inhibitors of Glutamate Racemase. ACS Med Chem Lett (2010) 0.84
Nature of allosteric inhibition in glutamate racemase: discovery and characterization of a cryptic inhibitory pocket using atomistic MD simulations and pKa calculations. J Phys Chem B (2011) 0.83
The mechanism of Bacillus anthracis intracellular germination requires multiple and highly diverse genetic loci. Infect Immun (2008) 0.83
Helicobacter pylori activation of PARP-1: usurping a versatile regulator of host cellular health. Gut Microbes (2011) 0.79
Helicobacter pylori activates NF-κB by inducing Ubc13-mediated ubiquitination of lysine 158 of TAK1. J Cell Biochem (2013) 0.79
Modification of a mammalian cell protein in the presence of [32P-adenylate]NAD: evidence for ADP ribosylation activity associated with Helicobacter pylori. Infect Immun (2006) 0.78