Published in Clin Cancer Res on April 01, 2002
A list of candidate cancer biomarkers for targeted proteomics. Biomark Insights (2007) 2.39
Telomere length in white blood cell DNA and lung cancer: a pooled analysis of three prospective cohorts. Cancer Res (2014) 1.35
Two panels of plasma microRNAs as non-invasive biomarkers for prediction of recurrence in resectable NSCLC. PLoS One (2013) 1.32
MicroRNA-mediated regulation of Ubc9 expression in cancer cells. Clin Cancer Res (2009) 1.32
Ubc9 promotes breast cell invasion and metastasis in a sumoylation-independent manner. Oncogene (2009) 1.31
Sumoylation and human disease pathogenesis. Trends Biochem Sci (2009) 1.29
SENP1 induces prostatic intraepithelial neoplasia through multiple mechanisms. J Biol Chem (2010) 1.29
Comprehensive characterization of cancer subtype associated long non-coding RNAs and their clinical implications. Sci Rep (2014) 1.08
Identification of genes down-regulated during lung cancer progression: a cDNA array study. J Exp Clin Cancer Res (2008) 1.01
Comparison of lung cancer cell lines representing four histopathological subtypes with gene expression profiling using quantitative real-time PCR. Cancer Cell Int (2010) 0.98
Role of SUMO/Ubc9 in DNA damage repair and tumorigenesis. J Mol Histol (2006) 0.96
Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy. Autophagy (2015) 0.95
Ribosomal protein s3: a multifunctional target of attaching/effacing bacterial pathogens. Front Microbiol (2011) 0.89
Identification of an N-terminal truncation of the NF-κB p65 subunit that specifically modulates ribosomal protein S3-dependent NF-κB gene expression. J Biol Chem (2012) 0.89
Starting and stopping SUMOylation. What regulates the regulator? Chromosoma (2013) 0.88
Covalent small ubiquitin-like modifier (SUMO) modification of Maf1 protein controls RNA polymerase III-dependent transcription repression. J Biol Chem (2013) 0.87
Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology. Biochim Biophys Acta (2014) 0.84
Recombinant human decorin suppresses liver HepG2 carcinoma cells by p21 upregulation. Onco Targets Ther (2012) 0.84
Decreased decorin expression in the tumor microenvironment. Cancer Med (2014) 0.83
A role for aberrantly expressed nuclear localized decorin in migration and invasion of dysplastic and malignant oral epithelial cells. Head Neck Oncol (2011) 0.83
Prognostic value of high FoxC2 expression in resectable non-small cell lung cancer, alone or in combination with E-cadherin expression. BMC Cancer (2016) 0.83
A SUMOylation Motif in Aurora-A: Implications for Spindle Dynamics and Oncogenesis. Front Oncol (2011) 0.82
Hypomethylation of the thymosin β(10) gene is not associated with its overexpression in non-small cell lung cancer. Mol Cells (2011) 0.81
The Extracellular Matrix in Epithelial Ovarian Cancer - A Piece of a Puzzle. Front Oncol (2015) 0.81
Estrogen receptor alpha and nuclear factor Y coordinately regulate the transcription of the SUMO-conjugating UBC9 gene in MCF-7 breast cancer cells. PLoS One (2013) 0.79
High expression of thymosin beta 10 predicts poor prognosis for hepatocellular carcinoma after hepatectomy. World J Surg Oncol (2014) 0.79
SUMO-2 promotes mRNA translation by enhancing interaction between eIF4E and eIF4G. PLoS One (2014) 0.78
Gene Therapy for Human Lung Adenocarcinoma Using a Suicide Gene Driven by a Lung-Specific Promoter Delivered by JC Virus-Like Particles. PLoS One (2016) 0.77
Poly(A)-specific ribonuclease and Nocturnin in squamous cell lung cancer: prognostic value and impact on gene expression. Mol Cancer (2015) 0.77
Opticin, a small leucine-rich proteoglycan, is uniquely expressed and translocated to the nucleus of chronic lymphocytic leukemia cells. Exp Hematol Oncol (2013) 0.77
A proline/arginine-rich end leucine-rich repeat protein (PRELP) variant is uniquely expressed in chronic lymphocytic leukemia cells. PLoS One (2013) 0.76
Identification of Biomarker and Co-Regulatory Motifs in Lung Adenocarcinoma Based on Differential Interactions. PLoS One (2015) 0.75
Systematic Analysis of the Genetic Variability That Impacts SUMO Conjugation and Their Involvement in Human Diseases. Sci Rep (2015) 0.75
HHLA2, a new immune checkpoint member of the B7 family, is widely expressed in human lung cancer and associated with EGFR mutational status. Clin Cancer Res (2016) 0.75
GPR171 expression enhances proliferation and metastasis of lung cancer cells. Oncotarget (2016) 0.75
SUMO and the robustness of cancer. Nat Rev Cancer (2017) 0.75
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell (2006) 7.49
Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell (2012) 6.09
Principles for the post-GWAS functional characterization of cancer risk loci. Nat Genet (2011) 3.73
A gene expression signature predicts survival of patients with stage I non-small cell lung cancer. PLoS Med (2006) 3.37
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. Hum Mol Genet (2009) 2.35
Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst (2008) 2.15
Anthocyanins and their role in cancer prevention. Cancer Lett (2008) 2.12
A high performance test of differential gene expression for oligonucleotide arrays. Genome Biol (2003) 2.03
Tumor susceptibility of Rassf1a knockout mice. Cancer Res (2005) 2.03
EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. Cancer Res (2007) 1.91
Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb. J Biol Chem (2007) 1.89
IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation. Proc Natl Acad Sci U S A (2011) 1.87
Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis (2012) 1.84
In situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry. Cancer Res (2003) 1.78
Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice. Nat Genet (2006) 1.77
Short-term modulation of cell proliferation and apoptosis and preventive/therapeutic efficacy of various agents in a mammary cancer model. Clin Cancer Res (2007) 1.73
Tissue self-affinity and polarized light scattering in the born approximation: a new model for precancer detection. Phys Rev Lett (2006) 1.58
Prospective grading of neoplastic change in rat esophagus epithelium using angle-resolved low-coherence interferometry. J Biomed Opt (2005) 1.56
Randomized phase II trial of lyophilized strawberries in patients with dysplastic precancerous lesions of the esophagus. Cancer Prev Res (Phila) (2011) 1.53
Conserved recurrent gene mutations correlate with pathway deregulation and clinical outcomes of lung adenocarcinoma in never-smokers. BMC Med Genomics (2014) 1.53
CD24 is a genetic modifier for risk and progression of multiple sclerosis. Proc Natl Acad Sci U S A (2003) 1.51
Preventive effects of NSAIDs, NO-NSAIDs, and NSAIDs plus difluoromethylornithine in a chemically induced urinary bladder cancer model. Cancer Prev Res (Phila) (2013) 1.45
Bioactive food components and cancer risk reduction. J Cell Biochem (2008) 1.42
Anthocyanins in black raspberries prevent esophageal tumors in rats. Cancer Prev Res (Phila) (2009) 1.41
MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer. Carcinogenesis (2012) 1.40
Detection of primary lung tumors in rodents by magnetic resonance imaging. Cancer Res (2004) 1.32
Chemopreventive properties of black raspberries in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis: down-regulation of cyclooxygenase-2, inducible nitric oxide synthase, and c-Jun. Cancer Res (2006) 1.28
Effects of a topically applied bioadhesive berry gel on loss of heterozygosity indices in premalignant oral lesions. Clin Cancer Res (2008) 1.25
Topical application of a bioadhesive black raspberry gel modulates gene expression and reduces cyclooxygenase 2 protein in human premalignant oral lesions. Cancer Res (2008) 1.24
Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus. PLoS One (2012) 1.24
Molecular profiling of mouse lung tumors: association with tumor progression, lung development, and human lung adenocarcinomas. Oncogene (2004) 1.23
LOH of chromosome 12p correlates with Kras2 mutation in non-small cell lung cancer. Oncogene (2003) 1.23
Chemoprevention of oral cancer by black raspberries. Anticancer Res (2003) 1.21
Coxibs and other nonsteroidal anti-inflammatory drugs in animal models of cancer chemoprevention. Cancer Prev Res (Phila) (2011) 1.20
Efficacy of new retinoids in the prevention of mammary cancers and correlations with short-term biomarkers. Carcinogenesis (2005) 1.19
Transitioning from preclinical to clinical chemopreventive assessments of lyophilized black raspberries: interim results show berries modulate markers of oxidative stress in Barrett's esophagus patients. Nutr Cancer (2006) 1.18
Quantitative monitoring of adenocarcinoma development in rodents by magnetic resonance imaging. Clin Cancer Res (2008) 1.18
Black raspberries inhibit N-nitrosomethylbenzylamine (NMBA)-induced angiogenesis in rat esophagus parallel to the suppression of COX-2 and iNOS. Carcinogenesis (2006) 1.17
Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models. Oncogene (2004) 1.16
Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2. Carcinogenesis (2004) 1.16
Inhibition of benzo(a)pyrene diol-epoxide-induced transactivation of activated protein 1 and nuclear factor kappaB by black raspberry extracts. Cancer Res (2002) 1.15
26S proteasome activity is down-regulated in lung cancer stem-like cells propagated in vitro. PLoS One (2010) 1.14
Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer. Proc Natl Acad Sci U S A (2014) 1.14
Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis. Clin Cancer Res (2004) 1.13
A chemically induced model for squamous cell carcinoma of the lung in mice: histopathology and strain susceptibility. Cancer Res (2004) 1.12
Common human cancer genes discovered by integrated gene-expression analysis. PLoS One (2007) 1.11
Differentially expressed genes associated with mouse lung tumor progression. Oncogene (2002) 1.10
Identification of cyanidin glycosides as constituents of freeze-dried black raspberries which inhibit anti-benzo[a]pyrene-7,8-diol-9,10-epoxide induced NFkappaB and AP-1 activity. Carcinogenesis (2006) 1.10
Large-scale in silico mapping of complex quantitative traits in inbred mice. PLoS One (2007) 1.08
Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1. Cancer Res (2009) 1.08
RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway. Cancer Res (2009) 1.07
Efficacy of polyphenon E, red ginseng, and rapamycin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. Neoplasia (2006) 1.06
Black raspberry extracts inhibit benzo(a)pyrene diol-epoxide-induced activator protein 1 activation and VEGF transcription by targeting the phosphotidylinositol 3-kinase/Akt pathway. Cancer Res (2006) 1.05
Chemoprevention of lung squamous cell carcinoma in mice by a mixture of Chinese herbs. Cancer Prev Res (Phila) (2009) 1.05
The use of animal models for cancer chemoprevention drug development. Semin Oncol (2010) 1.05
Alterations of gene expression in skin and lung of mice exposed to light and cigarette smoke. FASEB J (2004) 1.05
Chemoprevention of lung cancer by tea. Mol Nutr Food Res (2006) 1.05
Formulation and in-vitro and in-vivo evaluation of a mucoadhesive gel containing freeze dried black raspberries: implications for oral cancer chemoprevention. Pharm Res (2007) 1.05
Molecular alterations and lung tumors in p53 mutant mice exposed to cigarette smoke. Cancer Res (2003) 1.04
Budesonide exerts its chemopreventive efficacy during mouse lung tumorigenesis by modulating gene expressions. Oncogene (2004) 1.04
Anti-inflammatory effects of freeze-dried black raspberry powder in ulcerative colitis. Carcinogenesis (2010) 1.04
Prevention of mouse lung tumors by budesonide and its modulation of biomarkers. Carcinogenesis (2002) 1.03
Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients. Breast Cancer Res (2012) 1.03
5-aminosalicylic acid inhibits colitis-associated colorectal dysplasias in the mouse model of azoxymethane/dextran sulfate sodium-induced colitis. Inflamm Bowel Dis (2008) 1.03
Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC-MS/MS method. J Pharm Biomed Anal (2009) 1.03
Kaempferol inhibits UVB-induced COX-2 expression by suppressing Src kinase activity. Biochem Pharmacol (2010) 1.03
Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines. Cancer Res (2003) 1.03
Distribution of anthocyanins delivered from a bioadhesive black raspberry gel following topical intraoral application in normal healthy volunteers. Pharm Res (2009) 1.02
Enhancement of oral bioavailability of 20(S)-ginsenoside Rh2 through improved understanding of its absorption and efflux mechanisms. Drug Metab Dispos (2011) 1.01
Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer. Cancer Epidemiol Biomarkers Prev (2010) 1.01
Chemoprevention of rat prostate carcinogenesis by soy isoflavones and by Bowman-Birk inhibitor. Nutr Cancer (2007) 1.01
Effect of an epidermal growth factor receptor inhibitor in mouse models of lung cancer. Mol Cancer Res (2006) 1.01
Photochemoprevention of UVB-induced skin carcinogenesis in SKH-1 mice by brown algae polyphenols. Int J Cancer (2006) 1.00
Lung DNA adducts detected in human smokers are unrelated to typical polyaromatic carcinogens. Chem Res Toxicol (2006) 1.00
Null activity of selenium and vitamin e as cancer chemopreventive agents in the rat prostate. Cancer Prev Res (Phila) (2010) 0.99
Black raspberries inhibit intestinal tumorigenesis in apc1638+/- and Muc2-/- mouse models of colorectal cancer. Cancer Prev Res (Phila) (2010) 0.99
Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1. Cancer Res (2007) 0.98
Chemopreventive efficacy of naproxen and nitric oxide-naproxen in rodent models of colon, urinary bladder, and mammary cancers. Cancer Prev Res (Phila) (2009) 0.98
A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers. Cancer Res (2010) 0.98
Mechanisms and applications of non-steroidal anti-inflammatory drugs in the chemoprevention of cancer. Mutat Res (2003) 0.98
Inhibition of the growth of premalignant and malignant human oral cell lines by extracts and components of black raspberries. Nutr Cancer (2005) 0.98
Chemopreventive effects of a selective nitric oxide synthase inhibitor on carcinogen-induced rat esophageal tumorigenesis. Cancer Res (2004) 0.98
Overexpression of cyclooxygenase-2 in rat oral cancers and prevention of oral carcinogenesis in rats by selective and nonselective COX inhibitors. Cancer Prev Res (Phila) (2010) 0.98
Chemoprevention of genome, transcriptome, and proteome alterations induced by cigarette smoke in rat lung. Eur J Cancer (2005) 0.97
Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model. Carcinogenesis (2002) 0.96
Intestinal epithelial cell accumulation of the cancer preventive polyphenol ellagic acid--extensive binding to protein and DNA. Biochem Pharmacol (2003) 0.96
Lung-specific expression of human mutant p53-273H is associated with a high frequency of lung adenocarcinoma in transgenic mice. Oncogene (2002) 0.96
Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia. Cancer Res (2004) 0.96
Pepsin promotes proliferation of laryngeal and pharyngeal epithelial cells. Laryngoscope (2012) 0.96