Transcriptional regulation of a contractile gene by mechanical forces applied through integrins in osteoblasts.

PubWeight™: 0.90‹?›

🔗 View Article (PMID 11953441)

Published in J Biol Chem on April 12, 2002

Authors

Jiaxu Wang1, Ming Su, Jennie Fan, Arun Seth, Christopher A McCulloch

Author Affiliations

1: Canadian Institutes for Health Research Group in Matrix Dynamics, Faculty of Dentistry, University of Toronto, Toronto, Ontario M5S 3E8, Canada.

Articles by these authors

(truncated to the top 100)

Increasing hospital admission rates for urological complications after transrectal ultrasound guided prostate biopsy. J Urol (2010) 6.01

Cell mechanics: integrating cell responses to mechanical stimuli. Annu Rev Biomed Eng (2007) 3.70

Expression of TMPRSS2:ERG gene fusion in prostate cancer cells is an important prognostic factor for cancer progression. Cancer Biol Ther (2007) 2.97

Increasing hospital admission rates for urological complications after transrectal ultrasound guided prostate biopsy. J Urol (2013) 2.53

The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness. Nat Genet (2011) 2.48

Osteopontin expression is required for myofibroblast differentiation. Circ Res (2007) 2.33

Cell contact-dependent regulation of epithelial-myofibroblast transition via the rho-rho kinase-phospho-myosin pathway. Mol Biol Cell (2007) 2.29

Integrity of cell-cell contacts is a critical regulator of TGF-beta 1-induced epithelial-to-myofibroblast transition: role for beta-catenin. Am J Pathol (2004) 2.09

Force activates smooth muscle alpha-actin promoter activity through the Rho signaling pathway. J Cell Sci (2007) 2.03

Urinary biomarkers trefoil factor 3 and albumin enable early detection of kidney tubular injury. Nat Biotechnol (2010) 1.64

Gelsolin regulates cardiac remodeling after myocardial infarction through DNase I-mediated apoptosis. Circ Res (2009) 1.63

Differential and opposing regulation of PAI-1 promoter activity by estrogen receptor alpha and estrogen receptor beta in endothelial cells. Circ Res (2004) 1.53

Insulin like growth factor binding protein-7 reduces growth of human breast cancer cells and xenografted tumors. Breast Cancer Res Treat (2010) 1.50

Multifunctional roles of gelsolin in health and diseases. Med Res Rev (2010) 1.42

miR-146a and Krüppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation. EMBO Rep (2010) 1.39

Utility of incorporating genetic variants for the early detection of prostate cancer. Clin Cancer Res (2009) 1.39

Multiple roles of alpha-smooth muscle actin in mechanotransduction. Exp Cell Res (2005) 1.33

Cell death and mechanoprotection by filamin a in connective tissues after challenge by applied tensile forces. J Biol Chem (2002) 1.29

The role of FilGAP-filamin A interactions in mechanoprotection. Mol Biol Cell (2009) 1.28

4-thio-U cross-linking identifies the active site of the VS ribozyme. EMBO J (2002) 1.26

Src promotes estrogen-dependent estrogen receptor alpha proteolysis in human breast cancer. J Clin Invest (2007) 1.24

Autoubiquitination of BCA2 RING E3 ligase regulates its own stability and affects cell migration. Mol Cancer Res (2008) 1.21

Filamin A regulates cell spreading and survival via beta1 integrins. Exp Cell Res (2007) 1.20

A critical role for the membrane-type 1 matrix metalloproteinase in collagen phagocytosis. Mol Biol Cell (2006) 1.18

From tissue mechanics to transcription factors. Differentiation (2013) 1.16

Filamin A is required for vimentin-mediated cell adhesion and spreading. Am J Physiol Cell Physiol (2009) 1.15

Regulation of myofibroblast activities: calcium pulls some strings behind the scene. Exp Cell Res (2010) 1.13

Mice with a deletion in the first intron of the Col1a1 gene develop age-dependent aortic dissection and rupture. Circ Res (2003) 1.12

Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors. Biol Chem (2004) 1.12

Filamin A mediates interactions between cytoskeletal proteins that control cell adhesion. FEBS Lett (2010) 1.10

RNF11 is a multifunctional modulator of growth factor receptor signalling and transcriptional regulation. Eur J Cancer (2005) 1.10

IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors. Sci Signal (2012) 1.09

Evaluation of risk factors and clinicopathologic features for intrahepatic cholangiocarcinoma in Southern China: a possible role of hepatitis B virus. Ann Surg Oncol (2011) 1.08

Krüppel-like factor 4 promotes differentiation by transforming growth factor-beta receptor-mediated Smad and p38 MAPK signaling in vascular smooth muscle cells. J Biol Chem (2010) 1.06

Regulation of cell adhesion to collagen via beta1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon. Exp Cell Res (2010) 1.05

Lumican is a major proteoglycan component of the bone matrix. Matrix Biol (2002) 1.04

Poly-N-acetyl glucosamine nanofibers: a new bioactive material to enhance diabetic wound healing by cell migration and angiogenesis. Ann Surg (2009) 1.04

Phosphorylation of N-cadherin-associated cortactin by Fer kinase regulates N-cadherin mobility and intercellular adhesion strength. Mol Biol Cell (2005) 1.04

Nanoparticle location and material dependent dose enhancement in X-ray radiation therapy. J Phys Chem C Nanomater Interfaces (2012) 1.04

Versican G3 promotes mouse mammary tumor cell growth, migration, and metastasis by influencing EGF receptor signaling. PLoS One (2010) 1.03

Regulation of gene expression by lithium and depletion of inositol in slices of adult rat cortex. Neuron (2005) 1.03

Glycogen synthase kinase-3 regulates formation of long lamellipodia in human keratinocytes. J Cell Sci (2003) 1.02

α11 integrin stimulates myofibroblast differentiation in diabetic cardiomyopathy. Cardiovasc Res (2012) 1.02

An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein. Oncogene (2004) 1.02

IGFBP7 reduces breast tumor growth by induction of senescence and apoptosis pathways. Breast Cancer Res Treat (2011) 1.00

Force-induced myofibroblast differentiation through collagen receptors is dependent on mammalian diaphanous (mDia). J Biol Chem (2010) 1.00

ABO blood type, diabetes and risk of gastrointestinal cancer in northern China. World J Gastroenterol (2012) 1.00

The collagen receptor DDR1 regulates cell spreading and motility by associating with myosin IIA. J Cell Sci (2009) 1.00

miR-221 Is down-regulated in TMPRSS2:ERG fusion-positive prostate cancer. Anticancer Res (2011) 0.99

New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort. Cancer Biol Ther (2011) 0.98

From melanocyte to metastatic malignant melanoma. Dermatol Res Pract (2010) 0.97

The RING-H2 protein RNF11 is differentially expressed in breast tumours and interacts with HECT-type E3 ligases. Biochim Biophys Acta (2003) 0.97

Nephronectin promotes osteoblast differentiation via the epidermal growth factor-like repeats. FEBS Lett (2010) 0.97

Gelsolin mediates collagen phagocytosis through a rac-dependent step. Mol Biol Cell (2003) 0.95

Glycogen synthase kinase-3 regulates cytoskeleton and translocation of Rac1 in long cellular extensions of human keratinocytes. Exp Cell Res (2004) 0.95

Characterization of a novel human breast cancer associated gene (BCA3) encoding an alternatively spliced proline-rich protein. Biochim Biophys Acta (2003) 0.95

Osteopontin is up-regulated and associated with neutrophil and macrophage infiltration in glioblastoma. Immunology (2010) 0.95

Collagen, type V, alpha1 (COL5A1) is regulated by TGF-beta in osteoblasts. Matrix Biol (2004) 0.94

SHP-2 modulates interleukin-1-induced Ca2+ flux and ERK activation via phosphorylation of phospholipase Cgamma1. J Biol Chem (2004) 0.94

FAK, PIP5KIgamma and gelsolin cooperatively mediate force-induced expression of alpha-smooth muscle actin. J Cell Sci (2009) 0.94

Calreticulin affects fibronectin-based cell-substratum adhesion via the regulation of c-Src activity. J Biol Chem (2007) 0.93

Expression and function of Ets-1 during experimental acute renal failure in rats. J Am Soc Nephrol (2004) 0.93

Molecular characterization of ring finger protein 11. Mol Cancer Res (2005) 0.92

Differential binding to dorsal and ventral cell surfaces of fibroblasts: effect on collagen phagocytosis. Exp Cell Res (2003) 0.91

Comparison of two quantitative polymerase chain reaction methods for detecting HER2/neu amplification. J Mol Diagn (2003) 0.91

Methylglyoxal inhibits the binding step of collagen phagocytosis. J Biol Chem (2007) 0.91

Mechanical induction of gene expression in connective tissue cells. Methods Cell Biol (2010) 0.90

Coordinate gene expression patterns during osteoblast maturation and retinoic acid treatment of MC3T3-E1 cells. J Bone Miner Metab (2002) 0.89

IL-1β enhances cell adhesion to degraded fibronectin. FASEB J (2012) 0.89

X-ray enabled detection and eradication of circulating tumor cells with nanoparticles. Biosens Bioelectron (2012) 0.88

Novel function of PERK as a mediator of force-induced apoptosis. J Biol Chem (2008) 0.88

Phosphorylation of SHP-2 regulates interactions between the endoplasmic reticulum and focal adhesions to restrict interleukin-1-induced Ca2+ signaling. J Biol Chem (2006) 0.88

Simultaneous detection of multiple biomarkers with over three orders of concentration difference using phase change nanoparticles. Anal Chem (2011) 0.88

Tyrosine phosphatase PTPalpha regulates focal adhesion remodeling through Rac1 activation. Am J Physiol Cell Physiol (2008) 0.87

Contrasting identity-by-descent estimators, association studies, and linkage analyses using the Framingham Heart Study data. BMC Proc (2009) 0.87

IL-1 induced release of Ca2+ from internal stores is dependent on cell-matrix interactions and regulates ERK activation. FASEB J (2003) 0.87

Actin polymerization stabilizes α4β1 integrin anchors that mediate monocyte adhesion. J Cell Biol (2012) 0.87

Lateral boundary mechanosensing by adherent cells in a collagen gel system. Biomaterials (2013) 0.86

TNNI3K, a cardiac-specific kinase, promotes physiological cardiac hypertrophy in transgenic mice. PLoS One (2013) 0.86

Breast cancer metastasis in a human bone NOD/SCID mouse model. Cancer Biol Ther (2007) 0.86

Clinicopathologic characteristics and prognoses for multicentric occurrence and intrahepatic metastasis in synchronous multinodular hepatocellular carcinoma patients. Asian Pac J Cancer Prev (2013) 0.86

Breast cancer-associated gene 3 (BCA3) is a novel Rac1-interacting protein. J Bone Miner Res (2007) 0.85

Lack of prognostic value of FCGR3A-V158F polymorphism in non-Hodgkin's lymphoma. Haematologica (2008) 0.85

Cyclin I is expressed in human breast cancer and closely associated with VEGF and KDR expression. Breast Cancer Res Treat (2005) 0.85

Multifunctional self-healing and self-reporting polymer composite with integrated conductive microwire networks. ACS Appl Mater Interfaces (2012) 0.85

A novel Bayesian network inference algorithm for integrative analysis of heterogeneous deep sequencing data. Cell Res (2013) 0.85

Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression. Biochem J (2013) 0.85

Filamin A protects cells against force-induced apoptosis by stabilizing talin- and vinculin-containing cell adhesions. FASEB J (2013) 0.85

A central role for the ring finger protein RNF11 in ubiquitin-mediated proteolysis via interactions with E2s and E3s. Oncogene (2004) 0.85

Kaempferol promotes apoptosis in human bladder cancer cells by inducing the tumor suppressor, PTEN. Int J Mol Sci (2013) 0.85

Antibacterial activity of the human host defence peptide LL-37 and selected synthetic cationic lipids against bacteria associated with oral and upper respiratory tract infections. J Antimicrob Chemother (2012) 0.85

Kinase-dependent adhesion to fibronectin: regulation by calreticulin. Exp Cell Res (2008) 0.84

Versican G3 domain modulates breast cancer cell apoptosis: a mechanism for breast cancer cell response to chemotherapy and EGFR therapy. PLoS One (2011) 0.84

Collagen phagocytosis by fibroblasts is regulated by decorin. J Biol Chem (2005) 0.84

Transforming growth factor-beta inhibits nephronectin-induced osteoblast differentiation. FEBS Lett (2010) 0.84

Protein-tyrosine phosphatase-alpha and Src functionally link focal adhesions to the endoplasmic reticulum to mediate interleukin-1-induced Ca2+ signaling. J Biol Chem (2009) 0.84

MiR-451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC1. J Cell Mol Med (2014) 0.84

Longitudinal comparison of cytokines in peri-implant fluid and gingival crevicular fluid in healthy mouths. J Periodontol (2014) 0.83

Apolipoprotein E expression in localized prostate cancers. Int J Oncol (2003) 0.83

KIT gene mutations and patterns of protein expression in mucosal and acral melanoma. J Cutan Med Surg (2012) 0.83