Published in J Gerontol A Biol Sci Med Sci on May 01, 2002
Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study. J Am Geriatr Soc (2009) 3.12
Association between late-life social activity and motor decline in older adults. Arch Intern Med (2009) 2.26
Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study. BMC Geriatr (2008) 2.08
Physical frailty in older persons is associated with Alzheimer disease pathology. Neurology (2008) 1.59
Change in frailty and risk of death in older persons. Exp Aging Res (2009) 1.54
Hormone therapy and physical function change among older women in the Women's Health Initiative: a randomized controlled trial. Menopause (2010) 1.48
Lifetime occupation and physical function: a prospective cohort study on persons aged 80 years and older living in a community. Occup Environ Med (2006) 1.47
Combinations of motor measures more strongly predict adverse health outcomes in old age: the rush memory and aging project, a community-based cohort study. BMC Med (2011) 1.33
Associations between body composition and gait-speed decline: results from the Health, Aging, and Body Composition study. Am J Clin Nutr (2013) 1.32
Trajectories of gait speed predict mortality in well-functioning older adults: the Health, Aging and Body Composition study. J Gerontol A Biol Sci Med Sci (2012) 1.29
A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial. BMC Med (2013) 1.22
Apolipoprotein E e4 allele is associated with more rapid motor decline in older persons. Alzheimer Dis Assoc Disord (2009) 1.22
Physical performance characteristics of assisted living residents and risk for adverse health outcomes. Gerontologist (2008) 1.16
The role of androgens and estrogens on healthy aging and longevity. J Gerontol A Biol Sci Med Sci (2012) 1.13
Physical function in older candidates for renal transplantation: an impaired population. Clin J Am Soc Nephrol (2009) 1.11
Fat mass loss predicts gain in physical function with intentional weight loss in older adults. J Gerontol A Biol Sci Med Sci (2012) 1.09
Disability among older American Indians and Alaska Natives: an analysis of the 2000 Census Public Use Microdata Sample. Gerontologist (2007) 1.04
Incident parkinsonism in older adults without Parkinson disease. Neurology (2016) 1.04
Effect of a multifactorial interdisciplinary intervention on mobility-related disability in frail older people: randomised controlled trial. BMC Med (2012) 1.03
A life-course approach to healthy ageing: maintaining physical capability. Proc Nutr Soc (2014) 1.02
Exploring the hierarchy of mobility performance in high-functioning older women. J Gerontol A Biol Sci Med Sci (2007) 1.01
The role of metabolic syndrome, adiposity, and inflammation in physical performance in the Health ABC Study. J Gerontol A Biol Sci Med Sci (2012) 0.99
Terminal decline in motor function. Psychol Aging (2012) 0.97
Statins, angiotensin-converting enzyme inhibitors, and physical performance in older women. J Am Geriatr Soc (2012) 0.97
Relationship of physical function to vastus lateralis capillary density and metabolic enzyme activity in elderly men and women. Aging Clin Exp Res (2008) 0.95
ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study. J Am Med Dir Assoc (2009) 0.95
Is symptomatic knee osteoarthritis a risk factor for a trajectory of fast decline in gait speed? Results from a longitudinal cohort study. Arthritis Care Res (Hoboken) (2013) 0.90
Sex differences in the level and rate of change of physical function and grip strength in the Danish 1905-cohort study. J Aging Health (2010) 0.90
Vibratory thresholds and mobility in older persons. Muscle Nerve (2009) 0.87
Toward a positive aging phenotype for older women: observations from the women's health initiative. J Gerontol A Biol Sci Med Sci (2012) 0.87
Structural and functional markers of health depending on lifestyle in elderly women from Poland. Clin Interv Aging (2015) 0.86
Relationship between the occiput-wall distance and physical performance in the elderly: a cross sectional study. Aging Clin Exp Res (2007) 0.86
A post-hospital home exercise program improved mobility but increased falls in older people: a randomised controlled trial. PLoS One (2014) 0.84
Long-term trajectories of lower extremity function in older adults: estimating gender differences while accounting for potential mortality bias. J Gerontol A Biol Sci Med Sci (2012) 0.83
Correlations of Handgrip Strength with Selected Hand-Arm-Anthropometric Variables in Indian Inter-university Female Volleyball Players. Asian J Sports Med (2011) 0.82
Functional changes during hospital stay in older patients admitted to an acute care ward: a multicenter observational study. PLoS One (2014) 0.80
Association between physiological falls risk and physical performance tests among community-dwelling older adults. Clin Interv Aging (2015) 0.80
Effectiveness of a multifactorial intervention on preventing development of frailty in pre-frail older people: study protocol for a randomised controlled trial. BMJ Open (2015) 0.79
Incident preclinical mobility disability (PCMD) increases future risk of new difficulty walking and reduction in walking activity. Arch Gerontol Geriatr (2011) 0.79
Associations of behavioural risk factors and health status with changes in physical capability over 10 years of follow-up: the MRC National Survey of Health and Development. BMJ Open (2016) 0.78
Sex Differences in Concomitant Trajectories of Self-Reported Disability and Measured Physical Capacity in Older Adults. J Gerontol A Biol Sci Med Sci (2016) 0.78
Sex differences in the association of fasting and postchallenge glucose levels with grip strength among older adults: the Rancho Bernardo Study. BMJ Open Diabetes Res Care (2015) 0.77
The effects of a long-term physical activity intervention on serum uric acid in older adults at risk for physical disability. J Aging Phys Act (2013) 0.76
Feasibility and benefits of group-based exercise in residential aged care adults: a pilot study for the GrACE programme. PeerJ (2016) 0.76
Caregiving frequency and physical function: the Women's Health Initiative. J Gerontol A Biol Sci Med Sci (2014) 0.75
The combined effects of tai chi, resistance training, and diet on physical function and body composition in obese older women. J Aging Res (2014) 0.75
Assessing physical and cognitive function of older adults in continuing care retirement communities: who are we recruiting? Contemp Clin Trials (2014) 0.75
The Association Between Fall History and Physical Performance Tests in the Community-Dwelling Elderly: A Cross-Sectional Analysis. Ann Rehabil Med (2017) 0.75
Effect of affordable technology on physical activity levels and mobility outcomes in rehabilitation: a protocol for the Activity and MObility UsiNg Technology (AMOUNT) rehabilitation trial. BMJ Open (2016) 0.75
Older women with dementia can perform fast alternating forearm movements and performance is correlated with tests of lower extremity function. Clin Interv Aging (2013) 0.75
Fall Prevention in a Primary Care Setting. Dtsch Arztebl Int (2016) 0.75
Measures of fine motor skills in people with tremor disorders: appraisal and interpretation. Front Neurol (2013) 0.75
Associations Between Self-Reported Physical Activity and Physical Performance Measures Over Time in Postmenopausal Women: The Women's Health Initiative. J Am Geriatr Soc (2017) 0.75
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA (2005) 20.53
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature (2009) 19.56
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry (2010) 8.02
Phenotype of frailty: characterization in the women's health and aging studies. J Gerontol A Biol Sci Med Sci (2006) 8.00
Patterns of functional decline at the end of life. JAMA (2003) 7.79
Physical performance measures in the clinical setting. J Am Geriatr Soc (2003) 7.67
Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis. JAMA (2003) 7.42
Clopidogrel with or without omeprazole in coronary artery disease. N Engl J Med (2010) 7.39
Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability. JAMA (2006) 6.93
Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation (2005) 6.89
Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc (2006) 6.81
Effects of Testosterone Treatment in Older Men. N Engl J Med (2016) 6.66
Effects of a physical activity intervention on measures of physical performance: Results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study. J Gerontol A Biol Sci Med Sci (2006) 6.61
Frailty consensus: a call to action. J Am Med Dir Assoc (2013) 6.54
Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study. J Am Geriatr Soc (2005) 6.54
Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial. Arthritis Rheum (2004) 6.46
Ginkgo biloba for prevention of dementia: a randomized controlled trial. JAMA (2008) 6.00
Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus report. J Am Geriatr Soc (2004) 5.80
Physician-related barriers to the effective management of uncontrolled hypertension. Arch Intern Med (2002) 5.80
Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol (1985) (2003) 5.73
Frailty as a predictor of surgical outcomes in older patients. J Am Coll Surg (2010) 5.72
Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study. Arch Intern Med (2002) 4.97
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation (2003) 4.67
Differences in life expectancy due to race and educational differences are widening, and many may not catch up. Health Aff (Millwood) (2012) 4.36
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Functional decline in peripheral arterial disease: associations with the ankle brachial index and leg symptoms. JAMA (2004) 4.27
Chronic musculoskeletal pain and the occurrence of falls in an older population. JAMA (2009) 4.18
The origins of age-related proinflammatory state. Blood (2004) 4.15
Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study. J Gerontol A Biol Sci Med Sci (2002) 4.00
Inflammatory markers and physical performance in older persons: the InCHIANTI study. J Gerontol A Biol Sci Med Sci (2004) 3.96
Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study. Lancet (2002) 3.88
The association between obesity and the frailty syndrome in older women: the Women's Health and Aging Studies. J Am Geriatr Soc (2005) 3.73
Red blood cell distribution width and the risk of death in middle-aged and older adults. Arch Intern Med (2009) 3.71
Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers. J Clin Endocrinol Metab (2005) 3.70
Cognitive impairment and decline are associated with carotid artery disease in patients without clinically evident cerebrovascular disease. Ann Intern Med (2004) 3.66
Agreement between self-report of disease diagnoses and medical record validation in disabled older women: factors that modify agreement. J Am Geriatr Soc (2004) 3.52
Thyroid status, cardiovascular risk, and mortality in older adults. JAMA (2006) 3.50
Anemia is associated with disability and decreased physical performance and muscle strength in the elderly. J Am Geriatr Soc (2004) 3.48
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study. PLoS Genet (2009) 3.38
The ankle brachial index is associated with leg function and physical activity: the Walking and Leg Circulation Study. Ann Intern Med (2002) 3.32
Handgrip strength and cause-specific and total mortality in older disabled women: exploring the mechanism. J Am Geriatr Soc (2003) 3.30
Chronic cytomegalovirus infection and inflammation are associated with prevalent frailty in community-dwelling older women. J Am Geriatr Soc (2005) 3.29
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels. J Am Geriatr Soc (2002) 3.21
Nonlinear multisystem physiological dysregulation associated with frailty in older women: implications for etiology and treatment. J Gerontol A Biol Sci Med Sci (2009) 3.14
Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study. J Am Geriatr Soc (2009) 3.12
Physical activity, APOE genotype, and dementia risk: findings from the Cardiovascular Health Cognition Study. Am J Epidemiol (2005) 3.10
Relationship between low levels of anabolic hormones and 6-year mortality in older men: the aging in the Chianti Area (InCHIANTI) study. Arch Intern Med (2007) 2.88
Neighborhood context and mortality among older Mexican Americans: is there a barrio advantage? Am J Public Health (2004) 2.87
Falls and fear of falling: which comes first? A longitudinal prediction model suggests strategies for primary and secondary prevention. J Am Geriatr Soc (2002) 2.85
Interleukin-6 in aging and chronic disease: a magnificent pathway. J Gerontol A Biol Sci Med Sci (2006) 2.85
The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A Biol Sci Med Sci (2014) 2.84
The effects of cognitive impairment on mortality among hospitalized patients with heart failure. Am J Med (2003) 2.83
The presence of frailty in elderly persons with chronic renal insufficiency. Am J Kidney Dis (2004) 2.83
Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project. J Gerontol A Biol Sci Med Sci (2012) 2.82
The Four-Dimensional Symptom Questionnaire (4DSQ): a validation study of a multidimensional self-report questionnaire to assess distress, depression, anxiety and somatization. BMC Psychiatry (2006) 2.80
The lifestyle interventions and independence for elders (LIFE) pilot study: design and methods. Contemp Clin Trials (2005) 2.79
Reliability and sensitivity to change assessed for a summary measure of lower body function: results from the Women's Health and Aging Study. J Clin Epidemiol (2002) 2.79
Trends in length of stay, living setting, functional outcome, and mortality following medical rehabilitation. JAMA (2004) 2.77
Inflammatory markers and depressed mood in older persons: results from the Health, Aging and Body Composition study. Biol Psychiatry (2003) 2.77
Executive function correlates with walking speed in older persons: the InCHIANTI study. J Am Geriatr Soc (2005) 2.75
Genome-wide association of major depression: description of samples for the GAIN Major Depressive Disorder Study: NTR and NESDA biobank projects. Eur J Hum Genet (2008) 2.75
HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailty. J Gerontol A Biol Sci Med Sci (2007) 2.75
Adherence to guidelines is a predictor of outcome in chronic heart failure: the MAHLER survey. Eur Heart J (2005) 2.74
Frailty, hospitalization, and progression of disability in a cohort of disabled older women. Am J Med (2005) 2.74
Physical performance in peripheral arterial disease: a slower rate of decline in patients who walk more. Ann Intern Med (2006) 2.73
Insulin resistance and inflammation as precursors of frailty: the Cardiovascular Health Study. Arch Intern Med (2007) 2.71
Gradient of disability across the socioeconomic spectrum in the United States. N Engl J Med (2006) 2.67
Inflammation and frailty in older women. J Am Geriatr Soc (2007) 2.66
Antihypertensive drugs decrease risk of Alzheimer disease: Ginkgo Evaluation of Memory Study. Neurology (2013) 2.61
Measures of physical performance and risk for progressive and catastrophic disability: results from the Women's Health and Aging Study. J Gerontol A Biol Sci Med Sci (2005) 2.59
Neurological examination findings to predict limitations in mobility and falls in older persons without a history of neurological disease. Am J Med (2004) 2.58
Depression is associated with decreased blood pressure, but antidepressant use increases the risk for hypertension. Hypertension (2009) 2.58