PubRank

David Engelberg

Author PubWeight™ 27.66‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 ROS, stress-activated kinases and stress signaling in cancer. EMBO Rep 2002 2.61
2 Cisplatin-induced activation of the EGF receptor. Oncogene 2002 1.48
3 Procedure for controlling number of repeats, orientation, and order during cloning of oligonucleotides. Biotechniques 2004 1.39
4 Active mutants of the human p38alpha mitogen-activated protein kinase. J Biol Chem 2004 1.20
5 SSeCKS/Gravin/AKAP12 inhibits cancer cell invasiveness and chemotaxis by suppressing a protein kinase C- Raf/MEK/ERK pathway. J Biol Chem 2009 1.19
6 Intrinsically active variants of all human p38 isoforms. FEBS J 2007 1.15
7 Structures of p38alpha active mutants reveal conformational changes in L16 loop that induce autophosphorylation and activation. J Mol Biol 2006 1.14
8 HSF and Msn2/4p can exclusively or cooperatively activate the yeast HSP104 gene. Mol Microbiol 2002 1.11
9 Isolation of intrinsically active (MEK-independent) variants of the ERK family of mitogen-activated protein (MAP) kinases. J Biol Chem 2008 1.09
10 Hyperactive variants of p38alpha induce, whereas hyperactive variants of p38gamma suppress, activating protein 1-mediated transcription. J Biol Chem 2006 1.08
11 A novel lipid binding site formed by the MAP kinase insert in p38 alpha. J Mol Biol 2007 0.99
12 p38alpha is active in vitro and in vivo when monophosphorylated at threonine 180. Biochemistry 2009 0.99
13 Phosphorylation of Tyr-176 of the yeast MAPK Hog1/p38 is not vital for Hog1 biological activity. J Biol Chem 2003 0.92
14 When expressed in yeast, mammalian mitogen-activated protein kinases lose proper regulation and become spontaneously phosphorylated. Biochem J 2009 0.91
15 Combination of two activating mutations in one HOG1 gene forms hyperactive enzymes that induce growth arrest. Mol Cell Biol 2003 0.91
16 Commonly used Saccharomyces cerevisiae strains (e.g. BY4741, W303) are growth sensitive on synthetic complete medium due to poor leucine uptake. FEMS Microbiol Lett 2007 0.90
17 Turbidostat culture of Saccharomyces cerevisiae W303-1A under selective pressure elicited by ethanol selects for mutations in SSD1 and UTH1. FEMS Yeast Res 2012 0.85
18 Active mutants of the TCR-mediated p38α alternative activation site show changes in the phosphorylation lip and DEF site formation. J Mol Biol 2010 0.84
19 MAP-quest: could we produce constitutively active variants of MAP kinases? Mol Cell Endocrinol 2006 0.83
20 JX401, A p38alpha inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast. Mol Pharmacol 2006 0.82
21 A detailed protocol for chromatin immunoprecipitation in the yeast Saccharomyces cerevisiae. Methods Mol Biol 2010 0.81
22 Osmostress induces autophosphorylation of Hog1 via a C-terminal regulatory region that is conserved in p38α. PLoS One 2012 0.81
23 The yeast MAPK Hog1 is not essential for immediate survival under osmostress. FEBS Lett 2009 0.81
24 Overexpression of PDE2 or SSD1-V in Saccharomyces cerevisiae W303-1A strain renders it ethanol-tolerant. FEMS Yeast Res 2012 0.80
25 DEF pocket in p38α facilitates substrate selectivity and mediates autophosphorylation. J Biol Chem 2013 0.79
26 High-resolution diffracting crystals of intrinsically active p38alpha MAP kinase: a case study for low-throughput approaches. Acta Crystallogr D Biol Crystallogr 2007 0.78
27 Conformational bias imposed by source microseeds results in structural ambiguity. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.78
28 A "molecular evolution" approach for isolation of intrinsically active (MEK-independent) MAP kinases. Methods Mol Biol 2010 0.75