Published in J Biol Chem on May 28, 2002
Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol (2004) 1.95
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Synopsis and data synthesis of genetic association studies in hypertension for the adrenergic receptor family genes: the CUMAGAS-HYPERT database. Am J Hypertens (2009) 1.51
Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis. Nephrol Dial Transplant (2009) 1.49
Conformation state-sensitive antibodies to G-protein-coupled receptors. J Biol Chem (2006) 1.37
beta-adrenergic receptor gene polymorphisms and beta-blocker treatment outcomes in hypertension. Clin Pharmacol Ther (2008) 1.37
Correlation of renin angiotensin system (RAS) candidate gene polymorphisms with response to Ramipril in patients with essential hypertension. J Postgrad Med (2014) 1.25
Nuclear alpha1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes. Circ Res (2008) 1.20
Embracing emerging paradigms of G protein-coupled receptor agonism and signaling to address airway smooth muscle pathobiology in asthma. Naunyn Schmiedebergs Arch Pharmacol (2008) 1.13
Cardiovascular pharmacogenomics of adrenergic receptor signaling: clinical implications and future directions. Clin Pharmacol Ther (2011) 1.11
Beta-adrenoceptor polymorphisms. Naunyn Schmiedebergs Arch Pharmacol (2003) 1.09
Association analyses of adrenergic receptor polymorphisms with obesity and metabolic alterations. Metabolism (2007) 1.08
A common β1-adrenergic receptor polymorphism predicts favorable response to rate-control therapy in atrial fibrillation. J Am Coll Cardiol (2012) 1.06
Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade. Pharmacogenet Genomics (2008) 1.04
Shotgun metabolomics approach for the analysis of negatively charged water-soluble cellular metabolites from mouse heart tissue. Anal Chem (2007) 1.02
Mechanisms of pharmacogenomic effects of genetic variation within the cardiac adrenergic network in heart failure. Mol Pharmacol (2009) 1.00
Cardiac alpha1-adrenergic receptors: novel aspects of expression, signaling mechanisms, physiologic function, and clinical importance. Pharmacol Rev (2013) 0.96
No positive association between adrenergic receptor variants of alpha2cDel322-325, beta1Ser49, beta1Arg389 and the risk for heart failure in the Japanese population. Br J Clin Pharmacol (2005) 0.95
β1 adrenergic receptor polymorphisms and heart failure: a meta-analysis on susceptibility, response to β-blocker therapy and prognosis. PLoS One (2012) 0.93
The functional significance of genetic variation within the beta-adrenoceptor. Br J Clin Pharmacol (2005) 0.93
New advances in beta-blocker therapy in heart failure. Front Physiol (2013) 0.90
Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies. J Biol Chem (2008) 0.86
Automated imaging reveals a concentration dependent delay in reversibility of cardiac myocyte hypertrophy. J Mol Cell Cardiol (2012) 0.85
Genomics, heart failure and sudden cardiac death. Heart Fail Rev (2008) 0.84
Chronic heart failure: beta-blockers and pharmacogenetics. Eur J Clin Pharmacol (2008) 0.83
S49G and R389G polymorphisms of the β₁-adrenergic receptor influence signaling via the cAMP-PKA and ERK pathways. Physiol Genomics (2013) 0.82
Beta-blocker pharmacogenetics in heart failure. Heart Fail Rev (2008) 0.81
Polymorphisms of genes CYP2D6, ADRB1 and GNAS1 in pharmacokinetics and systemic effects of ophthalmic timolol. A pilot study. Eur J Clin Pharmacol (2005) 0.81
Pharmacogenomics of beta1-adrenergic receptor polymorphisms in heart failure. Heart Fail Clin (2010) 0.80
In patients chronically treated with metoprolol, the demand of inotropic catecholamine support after coronary artery bypass grafting is determined by the Arg389Gly-beta 1-adrenoceptor polymorphism. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.79
A combination of in vitro techniques for efficient discovery of functional monoclonal antibodies against human CXC chemokine receptor-2 (CXCR2). MAbs (2014) 0.79
Heart failure pharmacogenetics: past, present, and future. Curr Cardiol Rep (2011) 0.78
Impact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human β1-adrenoceptor. PLoS One (2013) 0.78
The Arg16Gly-β(2)-adrenoceptor single nucleotide polymorphism: exercise capacity and survival in patients with end-stage heart failure. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.78
Functional effects of β₁-adrenoceptor polymorphisms on the hemodynamic response to dobutamine with and without β-blocker administration. Clin Res Cardiol (2010) 0.78
Pharmacogenetics of ophthalmic topical beta-blockers. Per Med (2008) 0.77
RAAS and adrenergic genes in heart failure: Function, predisposition and survival implications. World J Cardiol (2010) 0.77
Tailoring therapy for heart failure: the pharmacogenomics of adrenergic receptor signaling. Pharmgenomics Pers Med (2014) 0.77
Pharmacogenomics in heart failure: where are we now and how can we reach clinical application? Cardiol Rev (2014) 0.76
Endogenous N-terminal Domain Cleavage Modulates α1D-Adrenergic Receptor Pharmacodynamics. J Biol Chem (2016) 0.76
Progress toward genetic tailoring of heart failure therapy. Curr Opin Mol Ther (2010) 0.75
Association of ADRB1 gene polymorphisms with pain sensitivity in a Chinese population. Int J Clin Exp Med (2015) 0.75
The Gordon Wilson Lecture: neurohormonal signaling pathways that link cardiac growth and death. Trans Am Clin Climatol Assoc (2007) 0.75
The effect of beta1-adrenergic receptor gene polymorphism on prolongation of corrected QT interval during endotracheal intubation under sevoflurane anesthesia. Korean J Anesthesiol (2011) 0.75
Bucindolol: a pharmacogenomic perspective on its use in chronic heart failure. Clin Med Insights Cardiol (2011) 0.75
Polymorphisms of β 1-adrenoreceptor gene and cardiovascular complications in patients with thyrotoxicosis. Biomed Res Int (2014) 0.75
Adrenergic Receptor Polymorphism and Maximal Exercise Capacity after Orthotopic Heart Transplantation. PLoS One (2016) 0.75
Site-specific O-Glycosylation by Polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-transferase T2) Co-regulates β1-Adrenergic Receptor N-terminal Cleavage. J Biol Chem (2017) 0.75
Receptor gene polymorphisms: lessons on functional relevance from the beta 1-adrenoceptor. Br J Pharmacol (2003) 0.75
Genetic Polymorphisms as Risk Stratification Tool in Primary Preventive ICD Therapy. ISRN Cardiol (2011) 0.75
Single-nucleotide polymorphisms in the β-adrenergic receptor genes are associated with lung allograft utilization. J Heart Lung Transplant (2011) 0.75
Genetic polymorphisms associated with heart failure: A literature review. J Int Med Res (2016) 0.75
Classification of the cardiomyopathies: a position statement from the European Society Of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J (2007) 6.34
Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor. Nat Med (2002) 2.75
Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation. Trends Pharmacol Sci (2005) 2.63
Intravenous levosimendan vs. dobutamine in acute decompensated heart failure patients on beta-blockers. Eur J Heart Fail (2010) 2.53
Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting. J Biol Chem (2004) 2.03
Expert consensus document from the European Society of Cardiology on catheter-based renal denervation. Eur Heart J (2013) 1.90
Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2. J Biol Chem (2002) 1.66
BRET analysis of GPCR oligomerization: newer does not mean better. Nat Methods (2007) 1.48
CXCR4-CCR5: a couple modulating T cell functions. Proc Natl Acad Sci U S A (2008) 1.47
Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors. J Biol Chem (2002) 1.44
Recruitment of activated G protein-coupled receptors to pre-existing clathrin-coated pits in living cells. J Biol Chem (2001) 1.44
Meningococcus Hijacks a β2-adrenoceptor/β-Arrestin pathway to cross brain microvasculature endothelium. Cell (2010) 1.43
Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies. Mol Biol Cell (2002) 1.39
Homo- and hetero-oligomerization of beta-arrestins in living cells. J Biol Chem (2005) 1.39
Assessment of pulmonary vascular resistance by Doppler echocardiography in patients with pulmonary arterial hypertension. J Heart Lung Transplant (2007) 1.32
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface. Blood (2008) 1.31
A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils. FASEB J (2003) 1.30
An escort for GPCRs: implications for regulation of receptor density at the cell surface. Trends Pharmacol Sci (2008) 1.29
Endoplasmic reticulum stress induces G2 cell-cycle arrest via mRNA translation of the p53 isoform p53/47. Mol Cell (2010) 1.26
Exploring symptoms in chronic heart failure. Eur J Heart Fail (2005) 1.25
Glycogenin-1 deficiency and inactivated priming of glycogen synthesis. N Engl J Med (2010) 1.20
Hydrotherapy--a new approach to improve function in the older patient with chronic heart failure. Eur J Heart Fail (2003) 1.20
Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins. Mol Cell Biol (2006) 1.19
The conserved isoleucine-valine-phenylalanine motif couples activation state and endocytic functions of beta-arrestins. Traffic (2007) 1.05
Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation control. PLoS One (2008) 1.04
beta-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53. Proc Natl Acad Sci U S A (2007) 1.03
Pharmacokinetic considerations of formulation: extended-release metoprolol succinate in the treatment of heart failure. J Cardiovasc Pharmacol (2003) 1.01
Ser49Gly of beta1-adrenergic receptor is associated with effective beta-blocker dose in dilated cardiomyopathy. Clin Pharmacol Ther (2005) 1.00
Nuclear functions for plasma membrane-associated proteins? Traffic (2003) 0.99
Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins. EMBO J (2011) 0.97
Immersion in warm water induces improvement in cardiac function in patients with chronic heart failure. Eur J Heart Fail (2005) 0.95
Risk of idiopathic dilated cardiomyopathy in 29 000 patients with celiac disease. J Am Heart Assoc (2012) 0.93
CXCR7 participates in CXCL12-induced CD34+ cell cycling through β-arrestin-dependent Akt activation. Blood (2013) 0.91
Using quantitative BRET to assess G protein-coupled receptor homo- and heterodimerization. Methods Mol Biol (2011) 0.90
Pathogenesis of meningococcemia. Cold Spring Harb Perspect Med (2013) 0.90
Mechanism of meningeal invasion by Neisseria meningitidis. Virulence (2012) 0.89
Self-assessed symptoms in chronic heart failure--important information for clinical management. Eur J Heart Fail (2006) 0.87
Antibodies against the beta1-adrenergic receptor induce progressive development of cardiomyopathy. J Mol Cell Cardiol (2007) 0.85
Gender and age related differences in left ventricular function and geometry with focus on the long axis. Eur J Echocardiogr (2005) 0.82
Impaired activation of IFN-gamma+CD4+ T cells in peripheral blood of patients with dilated cardiomyopathy. Cell Immunol (2010) 0.81
Benefit of warm water immersion on biventricular function in patients with chronic heart failure. Cardiovasc Ultrasound (2009) 0.81
Lower levels of the host protective IL-10 in DCM--a feature of autoimmune pathogenesis? Autoimmunity (2008) 0.81
Reliability of clinical muscular endurance tests in patients with chronic heart failure. Eur J Cardiovasc Nurs (2005) 0.80
Right ventricular ejection fraction during exercise as a predictor of mortality in patients awaiting lung transplantation: a cohort study. BMJ Open (2013) 0.80
On the dimerization of CCR5. Nat Immunol (2005) 0.80
TNFalpha antagonist upregulates interleukin-6 in rats with hypertensive heart failure. Int J Cardiol (2008) 0.78
Cardiorespiratory effects of warm water immersion in elderly patients with chronic heart failure. Clin Physiol Funct Imaging (2005) 0.77
Evidence for internal stores of CCR5 in blood cells. Blood (2011) 0.77
Influence of central inhibition of sympathetic nervous activity on myocardial metabolism in chronic heart failure: acute effects of the imidazoline I1-receptor agonist moxonidine. Clin Sci (Lond) (2006) 0.77
Neisseria meningitidis colonization of the brain endothelium and cerebrospinal fluid invasion. Cell Microbiol (2012) 0.77
Cardiac reserve in the transplanted heart: effect of a graft polymorphism in the beta1-adrenoceptor. J Heart Lung Transplant (2007) 0.76
Pulmonary hemodynamics as predictors of mortality in patients awaiting lung transplantation. Transpl Int (2007) 0.76
Regulated GPCR trafficking to the plasma membrane: general issues and the CCR5 chemokine receptor example. Subcell Biochem (2012) 0.76
[G protein coupled receptor endocytosis]. Med Sci (Paris) (2004) 0.76
Effect of catheter-based renal sympathetic denervation on 24-h ambulatory blood pressure in patients with resistant hypertension. Blood Press (2014) 0.75
The therapeutic potential of immune therapy in idiopathic dilated cardiomyopathy. Future Cardiol (2005) 0.75
[Catheter-based renal denervation: a new method for resistant hypertension. Initial experiences of the procedure shows significant decrease in blood pressure]. Lakartidningen (2013) 0.75
Pronounced improvement in systolic and diastolic ventricular long axis function after treatment with metoprolol. Eur J Heart Fail (2007) 0.75
Influence of age, hypertension, and diabetes on cardiac reserve in a rat model. J Am Soc Echocardiogr (2007) 0.75
[The unrestrained expansion of beta-arrestin functions spread to development]. Med Sci (Paris) (2005) 0.75
[β(2) adrenergic receptor and β-arrestins: the meningococcal instruments to breach meninges]. Med Sci (Paris) (2011) 0.75
Ginkgolide B stimulates signaling events in neutrophils and primes defense activities. Biochem Biophys Res Commun (2005) 0.75
[Peripartumcardiomyopathy an often missed diagnosis]. Lakartidningen (2013) 0.75
The function of left ventricular basal segments is most important for long-term recovery. Int J Cardiol (2007) 0.75
The validation of a new quality of life questionnaire for patients with congestive heart failure-an extension of the Cardiac Health Profile. Scand Cardiovasc J (2007) 0.75
Endothelin-1 across the lung circulation in patients with pulmonary arterial hypertension and influence of epoprostenol infusion. J Heart Lung Transplant (2009) 0.75
[Better and better results of heart transplantation. Analysis of 25 years of collected experiences]. Lakartidningen (2010) 0.75
[Classification of the cardiomyopathies]. Kardiol Pol (2008) 0.75
Effect of Calcineurin Inhibitor-Free Everolimus-Based Immunosuppressive Regimen on Albuminuria and Glomerular Filtration Rate after Heart Transplantation. Transplantation (2017) 0.75