Published in Immunity on May 01, 2002
gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis. Blood (2009) 2.07
Death versus survival: functional interaction between the apoptotic and stress-inducible heat shock protein pathways. J Clin Invest (2005) 2.06
The HSP70 family and cancer. Carcinogenesis (2013) 2.06
Sequestration of TRAF2 into stress granules interrupts tumor necrosis factor signaling under stress conditions. Mol Cell Biol (2005) 1.75
IL-17 produced by Paneth cells drives TNF-induced shock. J Exp Med (2008) 1.71
The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophages. J Immunol (2007) 1.43
Expression of heat shock proteins and heat shock protein messenger ribonucleic acid in human prostate carcinoma in vitro and in tumors in vivo. Cell Stress Chaperones (2005) 1.41
Regulation of apoptotic and inflammatory cell signaling in cerebral ischemia: the complex roles of heat shock protein 70. Anesthesiology (2008) 1.29
Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease. J Neurosci (2009) 1.24
LPS-induced cytokine levels are repressed by elevated expression of HSP70 in rats: possible role of NF-kappaB. Cell Stress Chaperones (2009) 1.06
Antioxidant and anti-inflammatory effects of exercise in diabetic patients. Exp Diabetes Res (2011) 1.06
Facets of heat shock protein 70 show immunotherapeutic potential. Immunology (2003) 1.04
Multiple hsp70 isoforms in the eukaryotic cytosol: mere redundancy or functional specificity? Curr Genomics (2008) 1.03
Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation. J Clin Invest (2012) 1.03
Inducible heat shock protein 70 expression as a potential predictive marker of metastasis in breast tumors. Cell Stress Chaperones (2006) 0.96
METTL21C is a potential pleiotropic gene for osteoporosis and sarcopenia acting through the modulation of the NF-κB signaling pathway. J Bone Miner Res (2014) 0.91
Anti-inflammatory properties and pharmacological induction of Hsp70 after brain injury. Inflammopharmacology (2012) 0.90
Hsp70 and cardiac surgery: molecular chaperone and inflammatory regulator with compartmentalized effects. Cell Stress Chaperones (2008) 0.90
Opposing roles for heat and heat shock proteins in macrophage functions during inflammation: a function of cell activation state? Front Immunol (2012) 0.85
Analysis of chaperone mRNA expression in the adult mouse brain by meta analysis of the Allen Brain Atlas. PLoS One (2010) 0.84
Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation. PLoS One (2013) 0.84
Induction of the 72-kilodalton heat shock protein and protection from ultraviolet B-induced cell death in human keratinocytes by repetitive exposure to heat shock or 15-deoxy-delta(12,14)-prostaglandin J2. Cell Stress Chaperones (2006) 0.83
The immune modulating properties of the heat shock proteins after brain injury. Anat Cell Biol (2013) 0.83
Potentiation of tumor necrosis factor-alpha-induced tumor cell apoptosis by a small molecule inhibitor for anti-apoptotic protein hPEBP4. J Biol Chem (2010) 0.82
Induction of heat shock protein 70 ameliorates ultraviolet-induced photokeratitis in mice. Int J Mol Sci (2013) 0.81
TNFR1-induced lethal inflammation is mediated by goblet and Paneth cell dysfunction. Mucosal Immunol (2014) 0.81
The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease. J Biol Chem (2014) 0.81
HSPA1A is upregulated in periodontal ligament at early stage of tooth movement in rats. Histochem Cell Biol (2010) 0.80
Apparently normal tumor necrosis factor receptor 1 signaling in the absence of the silencer of death domains. Mol Cell Biol (2003) 0.79
Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells. PLoS One (2013) 0.78
Mice overexpressing β-1,4-Galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis. PLoS One (2013) 0.78
Heat-shock response is associated with decreased production of interleukin-6 in murine aortic vascular smooth muscle cells. Naunyn Schmiedebergs Arch Pharmacol (2005) 0.78
Role of Exogenous Hsp72 on Liver Dysfunction during Sepsis. Biomed Res Int (2015) 0.78
Hsp70 regulates immune response in experimental autoimmune encephalomyelitis. PLoS One (2014) 0.77
Treadmill exercise preconditioning attenuates lung damage caused by systemic endotoxemia in type 1 diabetic rats. J Diabetes Res (2013) 0.77
Polymorphism of heat shock protein 70-2 and enterocutaneous fistula in Chinese population. World J Gastroenterol (2014) 0.76
Effect of resistance exercise training on expression of Hsp70 and inflammatory cytokines in skeletal muscle and adipose tissue of STZ-induced diabetic rats. Cell Stress Chaperones (2016) 0.75
De novo and rare mutations in the HSPA1L heat shock gene associated with inflammatory bowel disease. Genome Med (2017) 0.75
Klotho suppresses the inflammatory responses and ameliorates cardiac dysfunction in aging endotoxemic mice. Oncotarget (2017) 0.75
Nonlethal dose of silver nanoparticles attenuates TNF-α-induced hepatic epithelial cell death through HSP70 overexpression. Am J Physiol Cell Physiol (2015) 0.75
Enhanced intracellular heat shock protein 70 expression of leukocytes and serum interleukins release: comparison of on-pump and off-pump coronary artery surgery. World J Surg (2010) 0.75
Triptolide exerts protective effects against fibrosis following ileocolonic anastomosis by mechanisms involving the miR-16-1/HSP70 pathway in IL-10-deficient mice. Int J Mol Med (2017) 0.75
Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity (2002) 9.29
RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome. Immunity (2011) 3.53
Caspase-14 protects against epidermal UVB photodamage and water loss. Nat Cell Biol (2007) 2.82
Chemokine and cytokine processing by matrix metalloproteinases and its effect on leukocyte migration and inflammation. J Leukoc Biol (2007) 2.36
Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17. J Exp Med (2009) 2.28
Cecal ligation and puncture: the gold standard model for polymicrobial sepsis? Trends Microbiol (2011) 2.23
Distinct contribution of IL-6, TNF-alpha, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice. J Clin Invest (2004) 2.16
Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity. J Biol Chem (2006) 1.91
Alpha(1)-acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties. Cytokine Growth Factor Rev (2003) 1.72
IL-17 produced by Paneth cells drives TNF-induced shock. J Exp Med (2008) 1.71
Matrix metalloproteinase-8: cleavage can be decisive. Cytokine Growth Factor Rev (2006) 1.69
Disruption of tumor necrosis factor-alpha gene diminishes the development of atherosclerosis in ApoE-deficient mice. Atherosclerosis (2005) 1.66
A fully dissociated compound of plant origin for inflammatory gene repression. Proc Natl Acad Sci U S A (2005) 1.55
Modeling lymphangiogenesis in a three-dimensional culture system. Nat Methods (2008) 1.55
Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action. Cell Metab (2010) 1.49
Matrix metalloproteinases as drug targets in infections caused by gram-negative bacteria and in septic shock. Clin Microbiol Rev (2009) 1.49
MMP-2 and MMP-9 synergize in promoting choroidal neovascularization. FASEB J (2003) 1.42
The liver stage of Plasmodium berghei inhibits host cell apoptosis. Mol Microbiol (2005) 1.40
Activation of NMDA receptors promotes dendritic spine development through MMP-mediated ICAM-5 cleavage. J Cell Biol (2007) 1.38
N-glycomic changes in hepatocellular carcinoma patients with liver cirrhosis induced by hepatitis B virus. Hepatology (2007) 1.37
Contribution of host MMP-2 and MMP-9 to promote tumor vascularization and invasion of malignant keratinocytes. FASEB J (2004) 1.34
How glucocorticoid receptors modulate the activity of other transcription factors: a scope beyond tethering. Mol Cell Endocrinol (2012) 1.30
New insights into the anti-inflammatory mechanisms of glucocorticoids: an emerging role for glucocorticoid-receptor-mediated transactivation. Endocrinology (2013) 1.29
Resistance of collagenase-2 (matrix metalloproteinase-8)-deficient mice to TNF-induced lethal hepatitis. J Immunol (2005) 1.29
The wild-derived inbred mouse strain SPRET/Ei is resistant to LPS and defective in IFN-beta production. Proc Natl Acad Sci U S A (2006) 1.25
Type I interferon drives tumor necrosis factor-induced lethal shock. J Exp Med (2009) 1.25
Improved myocardial ischemia/reperfusion injury in mice lacking tumor necrosis factor-alpha. J Am Coll Cardiol (2002) 1.25
Inflammation: A nervous connection. Nature (2003) 1.21
Role of tumor necrosis factor-alpha in methamphetamine-induced drug dependence and neurotoxicity. J Neurosci (2004) 1.19
Endovascular injury induces rapid phenotypic changes in perivascular adipose tissue. Arterioscler Thromb Vasc Biol (2010) 1.18
Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages. Mol Immunol (2007) 1.18
Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF. EMBO Mol Med (2013) 1.17
Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1. Cytokine Growth Factor Rev (2011) 1.17
In vitro and in vivo protein-bound tyrosine nitration characterized by diagonal chromatography. Mol Cell Proteomics (2009) 1.16
On the trail of the glucocorticoid receptor: into the nucleus and back. Traffic (2011) 1.16
Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways. Diabetes (2008) 1.14
N-glycomic changes in serum proteins during human aging. Rejuvenation Res (2007) 1.13
Thirty years of Mus spretus: a promising future. Trends Genet (2009) 1.12
Lack of tumor necrosis factor alpha induces impaired proliferation of hepatitis B virus-specific cytotoxic T lymphocytes. J Virol (2003) 1.11
Role of Valpha 14 NKT cells in the development of impaired liver regeneration in vivo. Hepatology (2003) 1.10
Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages. FASEB J (2011) 1.10
Role of IFN-gamma and tumor necrosis factor-alpha in herpes simplex virus type 1 infection. J Interferon Cytokine Res (2002) 1.09
TNF-alpha contributes to the development of allergic rhinitis in mice. J Allergy Clin Immunol (2003) 1.09
Serum N-glycan profile shift during human ageing. Exp Gerontol (2010) 1.08
Tumor necrosis factor alpha mediates the lethal hepatotoxic effects of poly(I:C) in D-galactosamine-sensitized mice. Cytokine (2008) 1.07
IL-1-induced tumor necrosis factor-alpha elicits inflammatory cell infiltration in the skin by inducing IFN-gamma-inducible protein 10 in the elicitation phase of the contact hypersensitivity response. Int Immunol (2003) 1.06
Sensitive and specific detection of Yersinia pseudotuberculosis by loop-mediated isothermal amplification. J Clin Microbiol (2004) 1.04
Matrix metalloproteinases as drug targets in ischemia/reperfusion injury. Drug Discov Today (2011) 1.04
Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases. J Neurosci (2012) 1.04
Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation. J Clin Invest (2012) 1.03
Role of tumor necrosis factor-alpha and interferon-gamma in Helicobacter pylori infection. Microbiol Immunol (2004) 1.03
Erythrocytosis: the HIF pathway in control. Blood (2013) 1.01
Matrilysin (matrix metalloproteinase-7): a new promising drug target in cancer and inflammation? Cytokine Growth Factor Rev (2004) 1.01
Hypoxia-inducible factors as key regulators of tumor inflammation. Int J Cancer (2012) 1.01
Serum protein N-glycans profiling for the discovery of potential biomarkers for nonalcoholic steatohepatitis. J Proteome Res (2009) 1.00
Matrix metalloproteinase8 has a central role in inflammatory disorders and cancer progression. Cytokine Growth Factor Rev (2011) 1.00
UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers. Neoplasia (2008) 0.99
Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia. Stroke (2012) 0.99
Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury. J Biol Chem (2011) 0.99
N-glycan profiling in the study of human aging. Biogerontology (2008) 0.97
Inhibition of HIF prolyl hydroxylase-2 blocks tumor growth in mice through the antiproliferative activity of TGFβ. Cancer Res (2011) 0.97
Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium. J Clin Invest (2013) 0.96
Adenoviral gene transfer of ABIN-1 protects mice from TNF/galactosamine-induced acute liver failure and lethality. Hepatology (2005) 0.96
IFN-gamma and TNF-alpha are involved in urushiol-induced contact hypersensitivity in mice. Immunol Cell Biol (2005) 0.95
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis. Blood (2012) 0.95
Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in C57BL/6J x RR F2 mice. Biochem Genet (2004) 0.94
IFNβ produced by TLR4-activated tumor cells is involved in improving the antitumoral immune response. Cancer Res (2011) 0.93
Involvement of interleukin-6 and tumor necrosis factor alpha in CYP3A11 and 2C29 down-regulation by Bacillus Calmette-Guerin and lipopolysaccharide in mouse liver. Drug Metab Dispos (2004) 0.93
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism in schizophrenia is associated with age at onset and symptoms. Neurosci Lett (2006) 0.93
Tumor necrosis factor inhibits glucocorticoid receptor function in mice: a strong signal toward lethal shock. J Biol Chem (2011) 0.92
Crosstalk between TNF and glucocorticoid receptor signaling pathways. Cytokine Growth Factor Rev (2010) 0.92
LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome. EMBO Mol Med (2013) 0.92
Should we inhibit type I interferons in sepsis? Infect Immun (2006) 0.92
Controlling complexity: the clinical relevance of mouse complex genetics. Eur J Hum Genet (2013) 0.92
Loss of prolyl hydroxylase-2 in myeloid cells and T-lymphocytes impairs tumor development. Int J Cancer (2013) 0.91
Altered serum glycomics in Alzheimer disease: a potential blood biomarker? Rejuvenation Res (2010) 0.91
Hyporesponsiveness of SPRET/Ei mice to lethal shock induced by tumor necrosis factor and implications for a TNF-based antitumor therapy. Proc Natl Acad Sci U S A (2002) 0.91
N-glycan profiles as tools in diagnosis of hepatocellular carcinoma and prediction of healthy human ageing. Mech Ageing Dev (2008) 0.91
Loss of epithelial hypoxia-inducible factor prolyl hydroxylase 2 accelerates skin wound healing in mice. Mol Cell Biol (2013) 0.90
Pharmacological inhibition of type I interferon signaling protects mice against lethal sepsis. J Infect Dis (2013) 0.90
Tumor necrosis factor-alpha is required for gastritis induced by Helicobacter felis infection in mice. Microb Pathog (2004) 0.90
Acute abdominal distension secondary to urinary retention in a patient after alcohol withdrawal. Alcohol Alcohol (2004) 0.90
Protective effects of antimicrobial peptides derived from the beetle Allomyrina dichotoma defensin on endotoxic shock in mice. Int Immunopharmacol (2005) 0.90
Predictors of subjective and objective quality of life in outpatients with schizophrenia. Psychiatry Clin Neurosci (2008) 0.90
Quantitative trait locus analysis of plasma cholesterol and triglyceride levels in KK x RR F2 mice. Biochem Genet (2003) 0.90
Tnfa and Il-10 deficiencies have contrasting effects on lung tumor susceptibility: gender-dependent modulation of IL-10 haploinsufficiency. Mol Carcinog (2003) 0.89
Comparison of host resistance to primary and secondary Listeria monocytogenes infections in mice by intranasal and intravenous routes. Infect Immun (2002) 0.89
Mx1 causes resistance against influenza A viruses in the Mus spretus-derived inbred mouse strain SPRET/Ei. Cytokine (2008) 0.88
Intrabodies against the EVH1 domain of Wiskott-Aldrich syndrome protein inhibit T cell receptor signaling in transgenic mice T cells. FEBS J (2005) 0.88
Susceptibility of heat shock protein 70.1-deficient C57BL/6 J, wild-type C57BL/6 J and A/J mice to Trypanosoma congolense infection. Parasitol Res (2003) 0.87
Comprehensive overview of the structure and regulation of the glucocorticoid receptor. Endocr Rev (2014) 0.87
Occurrence of yersiniosis and listeriosis in wild boars in Japan. J Wildl Dis (2002) 0.87