Published in J Mol Biol on May 24, 2002
Three Prochlorococcus cyanophage genomes: signature features and ecological interpretations. PLoS Biol (2005) 4.55
X-ray observation of a transient hemiaminal trapped in a porous network. Nature (2009) 2.20
Phage auxiliary metabolic genes and the redirection of cyanobacterial host carbon metabolism. Proc Natl Acad Sci U S A (2011) 1.62
Twisted Schiff base intermediates and substrate locale revise transaldolase mechanism. Nat Chem Biol (2011) 0.86
Replacement of a phenylalanine by a tyrosine in the active site confers fructose-6-phosphate aldolase activity to the transaldolase of Escherichia coli and human origin. J Biol Chem (2008) 0.85
Transaldolase of Methanocaldococcus jannaschii. Archaea (2004) 0.84
The crystal structure of the Escherichia coli autoinducer-2 processing protein LsrF. PLoS One (2009) 0.83
Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence. J Am Chem Soc (2009) 0.83
Adherence to Bürgi-Dunitz stereochemical principles requires significant structural rearrangements in Schiff-base formation: insights from transaldolase complexes. Acta Crystallogr D Biol Crystallogr (2014) 0.79
Rational approaches for engineering novel functionalities in carbon-carbon bond forming enzymes. Comput Struct Biotechnol J (2012) 0.78
Building Bridges: Biocatalytic C-C-Bond Formation toward Multifunctional Products. ACS Catal (2016) 0.77
γ-Hydroxy-1,N2-propano-2'-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage. Chem Res Toxicol (2011) 0.77
Proteins evolve on the edge of supramolecular self-assembly. Nature (2017) 0.75
NMR analysis of covalent intermediates in thiamin diphosphate enzymes. Biochemistry (2003) 1.48
Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition. J Immunol (2004) 1.46
A new perspective on thiamine catalysis. Curr Opin Biotechnol (2004) 1.37
Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme alpha-aminoacrylate intermediate and an enzyme-inhibitor complex. J Biol Chem (2007) 1.17
Transaldolase: from biochemistry to human disease. Int J Biochem Cell Biol (2009) 1.14
Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation. EMBO J (2004) 1.13
Microbial aldolases as C-C bonding enzymes--unknown treasures and new developments. Appl Microbiol Biotechnol (2006) 1.13
The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family. J Biol Chem (2003) 1.11
Siroheme- and [Fe4-S4]-dependent NirA from Mycobacterium tuberculosis is a sulfite reductase with a covalent Cys-Tyr bond in the active site. J Biol Chem (2005) 1.10
Escherichia coli twin arginine (Tat) mutant translocases possessing relaxed signal peptide recognition specificities. J Biol Chem (2007) 1.09
Isolation and characterization of bifunctional Escherichia coli TatA mutant proteins that allow efficient tat-dependent protein translocation in the absence of TatB. J Biol Chem (2004) 1.08
Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid. Eur J Biochem (2003) 1.07
Recent progress in stereoselective synthesis with aldolases. Curr Opin Chem Biol (2010) 1.07
Crystal structure of the carbohydrate recognition domain of p58/ERGIC-53, a protein involved in glycoprotein export from the endoplasmic reticulum. J Biol Chem (2002) 1.06
Snapshot of a key intermediate in enzymatic thiamin catalysis: crystal structure of the alpha-carbanion of (alpha,beta-dihydroxyethyl)-thiamin diphosphate in the active site of transketolase from Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2002) 1.05
Genetic analysis of pathway specificity during posttranslational protein translocation across the Escherichia coli plasma membrane. J Bacteriol (2003) 1.03
Three-dimensional structures of apo- and holo-L-alanine dehydrogenase from Mycobacterium tuberculosis reveal conformational changes upon coenzyme binding. J Mol Biol (2008) 1.02
A structural basis for LCMV immune evasion: subversion of H-2D(b) and H-2K(b) presentation of gp33 revealed by comparative crystal structure.Analyses. Immunity (2002) 1.02
Peptidoglycan remodeling in Mycobacterium tuberculosis: comparison of structures and catalytic activities of RipA and RipB. J Mol Biol (2011) 1.02
Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity. J Mol Biol (2006) 1.02
Aclacinomycin oxidoreductase (AknOx) from the biosynthetic pathway of the antibiotic aclacinomycin is an unusual flavoenzyme with a dual active site. Proc Natl Acad Sci U S A (2007) 1.01
WAFL, a new protein involved in regulation of early endocytic transport at the intersection of actin and microtubule dynamics. Exp Cell Res (2008) 0.99
Structure of HI-6*sarin-acetylcholinesterase determined by X-ray crystallography and molecular dynamics simulation: reactivator mechanism and design. PLoS One (2009) 0.98
Systems metabolic engineering of Escherichia coli for production of the antitumor drugs violacein and deoxyviolacein. Metab Eng (2013) 0.97
The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.97
Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis. J Mol Biol (2007) 0.97
Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin. J Biol Chem (2002) 0.97
Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products. J Biol Chem (2004) 0.96
Structure of PA4019, a putative aromatic acid decarboxylase from Pseudomonas aeruginosa. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.96
Conformational changes during the catalytic cycle of gluconate kinase as revealed by X-ray crystallography. J Mol Biol (2002) 0.95
Crystal structure of aclacinomycin-10-hydroxylase, a S-adenosyl-L-methionine-dependent methyltransferase homolog involved in anthracycline biosynthesis in Streptomyces purpurascens. J Mol Biol (2003) 0.95
Crystal structure of an arthritogenic anticollagen immune complex. Arthritis Rheum (2011) 0.95
Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer. J Biol Chem (2002) 0.93
Cysteine synthase (CysM) of Mycobacterium tuberculosis is an O-phosphoserine sulfhydrylase: evidence for an alternative cysteine biosynthesis pathway in mycobacteria. J Biol Chem (2008) 0.93
Crystal structure of 1-deoxy-d-xylulose-5-phosphate reductoisomerase from Zymomonas mobilis at 1.9-A resolution. Biochim Biophys Acta (2004) 0.92
Aclacinomycin 10-hydroxylase is a novel substrate-assisted hydroxylase requiring S-adenosyl-L-methionine as cofactor. J Biol Chem (2004) 0.92
1.9 A structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.92
Crystal structure of the cofactor-independent monooxygenase SnoaB from Streptomyces nogalater: implications for the reaction mechanism. Biochemistry (2010) 0.90
Epitope-specific antibody response is controlled by immunoglobulin V(H) polymorphisms. J Exp Med (2014) 0.90
Structure determination by multiwavelength anomalous diffraction of aclacinomycin oxidoreductase: indications of multidomain pseudomerohedral twinning. Acta Crystallogr D Biol Crystallogr (2007) 0.89
Structural enzymology of sulphur metabolism in Mycobacterium tuberculosis. Biochem Biophys Res Commun (2010) 0.88
Phosphatase and oxygen radical-generating activities of mammalian purple acid phosphatase are functionally independent. Biochem Biophys Res Commun (2002) 0.88
Redesigning the active site of transaldolase TalB from Escherichia coli: new variants with improved affinity towards nonphosphorylated substrates. Chembiochem (2010) 0.87
Structural insights into the regulatory mechanism of the response regulator RocR from Pseudomonas aeruginosa in cyclic Di-GMP signaling. J Bacteriol (2012) 0.87
Structure of LdtMt2, an L,D-transpeptidase from Mycobacterium tuberculosis. Acta Crystallogr D Biol Crystallogr (2013) 0.87
Identification of late-stage glycosylation steps in the biosynthetic pathway of the anthracycline nogalamycin. Chembiochem (2011) 0.87
Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism. J Biol Chem (2003) 0.87
Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum. Acta Crystallogr D Biol Crystallogr (2008) 0.86
The C-terminal of CysM from Mycobacterium tuberculosis protects the aminoacrylate intermediate and is involved in sulfur donor selectivity. FEBS Lett (2008) 0.86
Structure of the branched-chain keto acid decarboxylase (KdcA) from Lactococcus lactis provides insights into the structural basis for the chemoselective and enantioselective carboligation reaction. Acta Crystallogr D Biol Crystallogr (2007) 0.86
Biosynthesis of the vitamin E compound delta-tocotrienol in recombinant Escherichia coli cells. Chembiochem (2008) 0.86
Production, crystallization and preliminary crystallographic study of the major cat allergen Fel d 1. Acta Crystallogr D Biol Crystallogr (2003) 0.86
A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity. J Biol Chem (2005) 0.85
Comparison of fluorescence and light scattering based methods to assess formation and stability of protein-protein complexes. J Struct Biol (2011) 0.85
Structural basis for substrate recognition and specificity in aklavinone-11-hydroxylase from rhodomycin biosynthesis. J Mol Biol (2009) 0.85
Replacement of a phenylalanine by a tyrosine in the active site confers fructose-6-phosphate aldolase activity to the transaldolase of Escherichia coli and human origin. J Biol Chem (2008) 0.85
Rational protein design of ThDP-dependent enzymes-engineering stereoselectivity. Chembiochem (2008) 0.85
Three-dimensional structure of iminodisuccinate epimerase defines the fold of the MmgE/PrpD protein family. J Mol Biol (2006) 0.84
TCA cycle involved enzymes SucA and Kgd, as well as MenD: efficient biocatalysts for asymmetric C-C bond formation. Org Lett (2013) 0.84
Discovery of an allosteric inhibitor binding site in 3-Oxo-acyl-ACP reductase from Pseudomonas aeruginosa. ACS Chem Biol (2013) 0.84
Structural proteomics: from the molecule to the system. Nat Struct Mol Biol (2007) 0.84
(S,S)-2,3-Dihydroxy-2,3-dihydrobenzoic acid: microbial access with engineered cells of Escherichia coli and application as starting material in natural-product synthesis. Chemistry (2003) 0.84
Structural basis of the differential stability and receptor specificity of H-2Db in complex with murine versus human beta2-microglobulin. J Mol Biol (2005) 0.83
High-resolution structures of oxidized and reduced thioredoxin reductase from Helicobacter pylori. Acta Crystallogr D Biol Crystallogr (2007) 0.83
Crystal structures of SnoaL2 and AclR: two putative hydroxylases in the biosynthesis of aromatic polyketide antibiotics. J Mol Biol (2006) 0.83
The polyketide cyclase RemF from Streptomyces resistomycificus contains an unusual octahedral zinc binding site. FEBS Lett (2009) 0.83
Fructose-6-phosphate aldolase in organic synthesis: preparation of D-fagomine, N-alkylated derivatives, and preliminary biological assays. Org Lett (2006) 0.82
The dual-specific active site of 7,8-diaminopelargonic acid synthase and the effect of the R391A mutation. Biochemistry (2002) 0.82
Structural insights into the UbiD protein family from the crystal structure of PA0254 from Pseudomonas aeruginosa. PLoS One (2013) 0.81
Design of a specific colonic mucus marker using a human commensal bacterium cell surface domain. J Biol Chem (2012) 0.81
A simple and reliable method to conduct and monitor expression cassette integration into the Escherichia coli chromosome. Biotechnol J (2010) 0.81
The transaldolase family: new synthetic opportunities from an ancient enzyme scaffold. Chembiochem (2011) 0.80
Three-dimensional structure of Fel d 1, the major allergen in cat. Int Arch Allergy Immunol (2003) 0.80
Crystal structure of the glycosyltransferase SnogD from the biosynthetic pathway of nogalamycin in Streptomyces nogalater. FEBS J (2012) 0.79
Broadening deoxysugar glycodiversity: natural and engineered transaldolases unlock a complementary substrate space. Chemistry (2011) 0.79
Transaldolase B: trapping of Schiff base intermediate between dihydroxyacetone and epsilon-amino group of active-site lysine residue by borohydride reduction. Methods Enzymol (2002) 0.79
RipD (Rv1566c) from Mycobacterium tuberculosis: adaptation of an NlpC/p60 domain to a non-catalytic peptidoglycan-binding function. Biochem J (2014) 0.78
Discovery of novel inhibitors targeting the Mycobacterium tuberculosis O-acetylserine sulfhydrylase (CysK1) using virtual high-throughput screening. Bioorg Med Chem Lett (2013) 0.78
Expression, purification and crystallization of the cofactor-independent monooxygenase SnoaB from the nogalamycin biosynthetic pathway. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.78
Structural basis for C-ribosylation in the alnumycin A biosynthetic pathway. Proc Natl Acad Sci U S A (2013) 0.78
Tetrahydrodipicolinate N-succinyltransferase and dihydrodipicolinate synthase from Pseudomonas aeruginosa: structure analysis and gene deletion. PLoS One (2012) 0.78
Construction of Escherichia coli strains with chromosomally integrated expression cassettes for the synthesis of 2'-fucosyllactose. Microb Cell Fact (2013) 0.78
Structure-guided design of novel thiazolidine inhibitors of O-acetyl serine sulfhydrylase from Mycobacterium tuberculosis. J Med Chem (2013) 0.78
Crystal structure and reactivity of YbdL from Escherichia coli identify a methionine aminotransferase function. FEBS Lett (2004) 0.78
Crystallization and preliminary crystallographic data of SnoaL, a polyketide cyclase in nogalamycin biosynthesis. Acta Crystallogr D Biol Crystallogr (2004) 0.77
Towards the in vivo production of tocotrienol compounds: engineering of a plasmid-free Escherichia coli strain for the heterologous synthesis of 2-methyl-6-geranylgeranyl-benzoquinol. J Biotechnol (2012) 0.77
Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis. Biochemistry (2004) 0.77
Expression, purification, refolding and crystallization of the carbohydrate-recognition domain of p58/ERGIC-53, an animal C-type lectin involved in export of glycoproteins from the endoplasmic reticulum. Acta Crystallogr D Biol Crystallogr (2002) 0.76
Diversity-oriented production of metabolites derived from chorismate and their use in organic synthesis. Angew Chem Int Ed Engl (2011) 0.76
Improvement of constraint-based flux estimation during L-phenylalanine production with Escherichia coli using targeted knock-out mutants. Biotechnol Bioeng (2014) 0.76
Crystal structure of NirD, the small subunit of the nitrite reductase NirbD from Mycobacterium tuberculosis at 2.0 Å resolution. Proteins (2012) 0.76
Expression, refolding and crystallization of murine MHC class I H-2Db in complex with human beta2-microglobulin. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.76
Improvement of L-phenylalanine production from glycerol by recombinant Escherichia coli strains: the role of extra copies of glpK, glpX, and tktA genes. Microb Cell Fact (2014) 0.76
Effect of coenzyme modification on the structural and catalytic properties of wild-type transketolase and of the variant E418A from Saccharomyces cerevisiae. FEBS J (2005) 0.76
Synthesis of the human milk oligosaccharide lacto-N-tetraose in metabolically engineered, plasmid-free E. coli. Chembiochem (2014) 0.76
An idea whose time has come. Genome Biol (2007) 0.76
Fluorogenic stereochemical probes for transaldolases. Chemistry (2003) 0.76