Published in Neuropsychopharmacology on July 01, 2002
Kalirin-7 is required for synaptic structure and function. J Neurosci (2008) 1.54
Kalirin-7 is an essential component of both shaft and spine excitatory synapses in hippocampal interneurons. J Neurosci (2008) 1.33
Trafficking and fusion of neuropeptide Y-containing dense-core granules in astrocytes. J Neurosci (2008) 0.95
Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. Neurobiol Dis (2009) 0.91
Structural plasticity of the adult brain: how animal models help us understand brain changes in depression and systemic disorders related to depression. Dialogues Clin Neurosci (2004) 0.90
Kalirin, a key player in synapse formation, is implicated in human diseases. Neural Plast (2012) 0.90
Peptidylgycine α-amidating monooxygenase and copper: a gene-nutrient interaction critical to nervous system function. J Neurosci Res (2010) 0.88
Peptidylglycine α-amidating monooxygenase heterozygosity alters brain copper handling with region specificity. J Neurochem (2013) 0.85
Haploinsufficiency in peptidylglycine alpha-amidating monooxygenase leads to altered synaptic transmission in the amygdala and impaired emotional responses. J Neurosci (2010) 0.83
Elimination of Kalrn expression in POMC cells reduces anxiety-like behavior and contextual fear learning. Horm Behav (2014) 0.80
Rapid and lasting enhancement of dopaminergic modulation at the hippocampal mossy fiber synapse by electroconvulsive treatment. J Neurophysiol (2016) 0.75
Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin. Neuron (2003) 3.40
Dioxygen binds end-on to mononuclear copper in a precatalytic enzyme complex. Science (2004) 2.57
Kalirin, a multifunctional Rho guanine nucleotide exchange factor, is necessary for maintenance of hippocampal pyramidal neuron dendrites and dendritic spines. J Neurosci (2003) 1.60
Kalirin-7 is required for synaptic structure and function. J Neurosci (2008) 1.54
Kalirin promotes neointimal hyperplasia by activating Rac in smooth muscle cells. Arterioscler Thromb Vasc Biol (2013) 1.54
Oxygen activation by the noncoupled binuclear copper site in peptidylglycine alpha-hydroxylating monooxygenase. Spectroscopic definition of the resting sites and the putative CuIIM-OOH intermediate. Biochemistry (2004) 1.36
Kalirin-7 is an essential component of both shaft and spine excitatory synapses in hippocampal interneurons. J Neurosci (2008) 1.33
Deletion of peptide amidation enzymatic activity leads to edema and embryonic lethality in the mouse. Dev Biol (2005) 1.29
Kalirin Dbl-homology guanine nucleotide exchange factor 1 domain initiates new axon outgrowths via RhoG-mediated mechanisms. J Neurosci (2002) 1.29
microRNA-Seq reveals cocaine-regulated expression of striatal microRNAs. RNA (2011) 1.26
Behavioral and morphological responses to cocaine require kalirin7. Biol Psychiatry (2010) 1.21
Kalirin: a dual Rho guanine nucleotide exchange factor that is so much more than the sum of its many parts. Neuroscientist (2005) 1.21
Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating Rac activation. BMC Cell Biol (2007) 1.19
Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac. Sci Signal (2011) 1.19
ATP7A (Menkes protein) functions in axonal targeting and synaptogenesis. Mol Cell Neurosci (2007) 1.14
Not all secretory granules are created equal: Partitioning of soluble content proteins. Mol Biol Cell (2006) 1.12
Multiple novel isoforms of Trio are expressed in the developing rat brain. Gene (2005) 1.11
Trafficking of a secretory granule membrane protein is sensitive to copper. J Biol Chem (2007) 1.09
Supplying copper to the cuproenzyme peptidylglycine alpha-amidating monooxygenase. J Biol Chem (2003) 1.09
Inhibitors of the V0 subunit of the vacuolar H+-ATPase prevent segregation of lysosomal- and secretory-pathway proteins. J Cell Sci (2009) 1.07
Synaptic plasticity, a symphony in GEF. ACS Chem Neurosci (2010) 1.06
Regulation of RhoGEF activity by intramolecular and intermolecular SH3 domain interactions. J Biol Chem (2006) 1.06
Genomic organization and differential expression of Kalirin isoforms. Gene (2002) 1.05
Menkes protein contributes to the function of peptidylglycine alpha-amidating monooxygenase. Endocrinology (2003) 1.04
Kalirin/Trio Rho guanine nucleotide exchange factors regulate a novel step in secretory granule maturation. Mol Biol Cell (2007) 1.03
Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function. J Neurosci (2011) 1.01
Regulation of Kalirin by Cdk5. J Cell Sci (2008) 0.99
Secretory granule to the nucleus: role of a multiply phosphorylated intrinsically unstructured domain. J Biol Chem (2009) 0.98
Mechanistic investigation of peptidylglycine alpha-hydroxylating monooxygenase via intrinsic tryptophan fluorescence and mutagenesis. Biochemistry (2003) 0.98
Cdk5 and Trio modulate endocrine cell exocytosis. J Cell Sci (2004) 0.98
The developmentally regulated expression of Menkes protein ATP7A suggests a role in axon extension and synaptogenesis. Dev Neurosci (2005) 0.97
The catalytic copper of peptidylglycine alpha-hydroxylating monooxygenase also plays a critical structural role. Biophys J (2005) 0.97
Amidation of bioactive peptides: the structure of the lyase domain of the amidating enzyme. Structure (2009) 0.96
Kalirin-7, an important component of excitatory synapses, is regulated by estradiol in hippocampal neurons. Hippocampus (2010) 0.96
Autonomous functions for the Sec14p/spectrin-repeat region of Kalirin. Exp Cell Res (2008) 0.96
Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease. Neurobiol Dis (2007) 0.95
Kalrn plays key roles within and outside of the nervous system. BMC Neurosci (2012) 0.95
Expression of Trio, a member of the Dbl family of Rho GEFs in the developing rat brain. J Comp Neurol (2005) 0.95
Kalirin expression is regulated by multiple promoters. J Mol Neurosci (2004) 0.94
Differential reactivity between two copper sites in peptidylglycine α-hydroxylating monooxygenase. J Am Chem Soc (2010) 0.94
Kalrn promoter usage and isoform expression respond to chronic cocaine exposure. BMC Neurosci (2011) 0.93
Induction of lamellipodia by Kalirin does not require its guanine nucleotide exchange factor activity. Exp Cell Res (2005) 0.93
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. PLoS One (2010) 0.93
Signaling from the secretory granule to the nucleus: Uhmk1 and PAM. Mol Endocrinol (2010) 0.92
Retrieval and reuse of pituitary secretory granule proteins. J Biol Chem (2005) 0.92
Neuronal Rho GEFs in synaptic physiology and behavior. Neuroscientist (2013) 0.91
The catalytic role of the copper ligand H172 of peptidylglycine alpha-hydroxylating monooxygenase (PHM): a spectroscopic study of the H172A mutant. Biochemistry (2002) 0.91
A novel auxiliary subunit critical to BK channel function in Caenorhabditis elegans. J Neurosci (2010) 0.91
Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. Neurobiol Dis (2009) 0.91
Essential features of the catalytic core of peptidyl-alpha-hydroxyglycine alpha-amidating lyase. Biochemistry (2002) 0.90
Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity. BMC Neurosci (2011) 0.89
Drosophila uses two distinct neuropeptide amidating enzymes, dPAL1 and dPAL2. J Neurochem (2004) 0.89
Flow cytometry-assisted purification and proteomic analysis of the corticotropes dense-core secretory granules. Proteomics (2008) 0.89
Monooxygenase X, a member of the copper-dependent monooxygenase family localized to the endoplasmic reticulum. J Biol Chem (2004) 0.89