Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
A mammalian microRNA expression atlas based on small RNA library sequencing.
|
Cell
|
2007
|
34.03
|
2
|
Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways.
|
Nat Genet
|
2005
|
6.67
|
3
|
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination.
|
Nat Genet
|
2003
|
5.24
|
4
|
Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis.
|
Nat Genet
|
2003
|
4.14
|
5
|
Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia.
|
Am J Hum Genet
|
2008
|
2.74
|
6
|
Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling.
|
Mol Cell Biol
|
2003
|
2.69
|
7
|
Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease.
|
J Am Soc Nephrol
|
2008
|
2.69
|
8
|
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling.
|
Cell
|
2012
|
2.54
|
9
|
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels.
|
Proc Natl Acad Sci U S A
|
2006
|
2.16
|
10
|
Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.
|
EMBO J
|
2005
|
2.12
|
11
|
PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.
|
J Clin Invest
|
2010
|
1.85
|
12
|
Nephrocystin specifically localizes to the transition zone of renal and respiratory cilia and photoreceptor connecting cilia.
|
J Am Soc Nephrol
|
2006
|
1.79
|
13
|
Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics.
|
J Clin Invest
|
2011
|
1.60
|
14
|
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation.
|
Nat Immunol
|
2011
|
1.49
|
15
|
Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity.
|
J Biol Chem
|
2008
|
1.43
|
16
|
The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1.
|
J Biol Chem
|
2003
|
1.42
|
17
|
KIBRA modulates directional migration of podocytes.
|
J Am Soc Nephrol
|
2008
|
1.36
|
18
|
NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway.
|
J Cell Biol
|
2011
|
1.34
|
19
|
Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags.
|
Nat Med
|
2013
|
1.22
|
20
|
Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1.
|
Genome Med
|
2009
|
1.15
|
21
|
p35, the non-cyclin activator of Cdk5, protects podocytes against apoptosis in vitro and in vivo.
|
Kidney Int
|
2010
|
1.12
|
22
|
Podocin organizes ion channel-lipid supercomplexes: implications for mechanosensation at the slit diaphragm.
|
Nephron Exp Nephrol
|
2007
|
1.03
|
23
|
Light microscopic visualization of podocyte ultrastructure demonstrates oscillating glomerular contractions.
|
Am J Pathol
|
2012
|
1.03
|
24
|
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.
|
EMBO J
|
2012
|
1.02
|
25
|
Intrinsic proinflammatory signaling in podocytes contributes to podocyte damage and prolonged proteinuria.
|
Am J Physiol Renal Physiol
|
2012
|
1.00
|
26
|
The von Hippel Lindau tumor suppressor limits longevity.
|
J Am Soc Nephrol
|
2009
|
1.00
|
27
|
Interaction of 14-3-3 protein with regulator of G protein signaling 7 is dynamically regulated by tumor necrosis factor-alpha.
|
J Biol Chem
|
2002
|
0.98
|
28
|
Listeria monocytogenes infection in macrophages induces vacuolar-dependent host miRNA response.
|
PLoS One
|
2011
|
0.97
|
29
|
Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression.
|
Hum Mol Genet
|
2013
|
0.96
|
30
|
Clinical spectrum and pathogenesis of nephronophthisis.
|
Curr Opin Nephrol Hypertens
|
2012
|
0.94
|
31
|
Comparative analysis of Neph gene expression in mouse and chicken development.
|
Histochem Cell Biol
|
2011
|
0.91
|
32
|
Extracellular phosphorylation of collagen XVII by ecto-casein kinase 2 inhibits ectodomain shedding.
|
J Biol Chem
|
2007
|
0.91
|
33
|
Dysregulated autophagy contributes to podocyte damage in Fabry's disease.
|
PLoS One
|
2013
|
0.91
|
34
|
Conditional loss of kidney microRNAs results in congenital anomalies of the kidney and urinary tract (CAKUT).
|
J Mol Med (Berl)
|
2013
|
0.90
|
35
|
The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ.
|
Hum Mol Genet
|
2012
|
0.90
|
36
|
Label-free quantitative proteomic analysis of the YAP/TAZ interactome.
|
Am J Physiol Cell Physiol
|
2014
|
0.90
|
37
|
The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signaling.
|
J Biol Chem
|
2012
|
0.89
|
38
|
Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia.
|
J Biol Chem
|
2011
|
0.87
|
39
|
Breaking the chain at the membrane: paraoxonase 2 counteracts lipid peroxidation at the plasma membrane.
|
FASEB J
|
2014
|
0.87
|
40
|
The centrosomal kinase Plk1 localizes to the transition zone of primary cilia and induces phosphorylation of nephrocystin-1.
|
PLoS One
|
2012
|
0.86
|
41
|
Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner.
|
Aging Cell
|
2013
|
0.81
|
42
|
Putting the brakes on p53-driven apoptosis.
|
Cell Cycle
|
2012
|
0.81
|
43
|
A disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology (PHB) domain protein podocin.
|
J Biol Chem
|
2014
|
0.79
|
44
|
Transition zone proteins and cilia dynamics.
|
Nat Genet
|
2011
|
0.78
|
45
|
Comparative phosphoproteomic analysis of mammalian glomeruli reveals conserved podocin C-terminal phosphorylation as a determinant of slit diaphragm complex architecture.
|
Proteomics
|
2015
|
0.78
|
46
|
Characterization of a short isoform of the kidney protein podocin in human kidney.
|
BMC Nephrol
|
2013
|
0.77
|
47
|
The BAR domain protein PICK1 regulates cell recognition and morphogenesis by interacting with Neph proteins.
|
Mol Cell Biol
|
2011
|
0.75
|