Published in J Infect Dis on May 16, 2002
How neutrophils kill microbes. Annu Rev Immunol (2005) 6.87
Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. EMBO J (2005) 4.18
Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice. PLoS Pathog (2009) 3.05
Myeloperoxidase: a front-line defender against phagocytosed microorganisms. J Leukoc Biol (2012) 1.60
Live imaging of disseminated candidiasis in zebrafish reveals role of phagocyte oxidase in limiting filamentous growth. Eukaryot Cell (2011) 1.34
Immune defence against Candida fungal infections. Nat Rev Immunol (2015) 1.19
Major basic protein from eosinophils and myeloperoxidase from neutrophils are required for protective immunity to Strongyloides stercoralis in mice. Infect Immun (2011) 1.14
Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis. Proc Natl Acad Sci U S A (2010) 1.12
Myeloperoxidase in human neutrophil host defence. Cell Microbiol (2014) 1.07
Candida albicans induces arginine biosynthetic genes in response to host-derived reactive oxygen species. Eukaryot Cell (2012) 0.95
Immune defence mechanisms and immunoenhancement strategies in oropharyngeal candidiasis. Expert Rev Mol Med (2008) 0.93
Role of sphingomyelin synthase in controlling the antimicrobial activity of neutrophils against Cryptococcus neoformans. PLoS One (2010) 0.92
The role of Candida albicans AP-1 protein against host derived ROS in in vivo models of infection. Virulence (2013) 0.90
Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition. PLoS Pathog (2016) 0.87
Impaired host defense against Sporothrix schenckii in mice with chronic granulomatous disease. Infect Immun (2004) 0.86
Absence of phagocyte NADPH oxidase 2 leads to severe inflammatory response in lungs of mice infected with Coccidioides. Microb Pathog (2011) 0.83
Chromatin-mediated Candida albicans virulence. Biochim Biophys Acta (2011) 0.78
The complex roles of NADPH oxidases in fungal infection. Cell Microbiol (2014) 0.76
Cell Intrinsic Galectin-3 Attenuates Neutrophil ROS-Dependent Killing of Candida by Modulating CR3 Downstream Syk Activation. Front Immunol (2017) 0.75
Different behavior of myeloperoxidase in two rodent amoebic liver abscess models. PLoS One (2017) 0.75
Genetic Phagocyte NADPH Oxidase Deficiency Enhances Nonviable Candida albicans-Induced Inflammation in Mouse Lungs. Inflammation (2016) 0.75
Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J Clin Invest (2002) 5.42
Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. Cell Signal (2005) 4.74
Activation of antibacterial autophagy by NADPH oxidases. Proc Natl Acad Sci U S A (2009) 3.87
Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I. J Clin Invest (2005) 3.25
Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages. J Biol Chem (2008) 2.87
Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology (2008) 2.73
Genomic diversity of enterohemorrhagic Escherichia coli O157 revealed by whole genome PCR scanning. Proc Natl Acad Sci U S A (2002) 2.70
Development and validation of a mismatch amplification mutation PCR assay to monitor the dissemination of an emerging variant of Vibrio cholerae O1 biotype El Tor. Microbiol Immunol (2008) 2.62
A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity. Blood (2009) 2.35
Recipes for creating animal models of diabetic cardiovascular disease. Circ Res (2007) 2.34
Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice. J Biol Chem (2003) 2.26
Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int (2004) 2.17
Stroke risk and antihypertensive drug treatment in the general population: the Japan arteriosclerosis longitudinal study. J Hypertens (2009) 2.11
Detection and characterization of focal hepatic lesions with diffusion-weighted MR imaging: a pictorial review. Abdom Imaging (2013) 2.11
BBE02 disruption mutants of Borrelia burgdorferi B31 have a highly transformable, infectious phenotype. Infect Immun (2004) 2.08
Critical roles of interferon regulatory factor 4 in CD11bhighCD8alpha- dendritic cell development. Proc Natl Acad Sci U S A (2004) 2.08
Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration. Proc Natl Acad Sci U S A (2002) 2.08
The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis. J Exp Med (2006) 2.03
Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3. Arterioscler Thromb Vasc Biol (2003) 2.00
The role of natriuretic peptides in cardioprotection. Cardiovasc Res (2005) 2.00
The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies. Am J Pathol (2005) 1.97
Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury. Am J Physiol Lung Cell Mol Physiol (2007) 1.97
Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells. EMBO J (2006) 1.97
Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis. Blood (2007) 1.92
Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARgamma. J Clin Invest (2004) 1.91
On the cyto-toxicity caused by quantum dots. Microbiol Immunol (2004) 1.90
Modification of the structure and activity of lipid A in Yersinia pestis lipopolysaccharide by growth temperature. Infect Immun (2002) 1.88
Renal vasculitis in Japan and the UK--are there differences in epidemiology and clinical phenotype? Nephrol Dial Transplant (2008) 1.85
Synergistic activation of the Arabidopsis NADPH oxidase AtrbohD by Ca2+ and phosphorylation. J Biol Chem (2008) 1.80
Spread of a chromosomal cefixime-resistant penA gene among different Neisseria gonorrhoeae lineages. Antimicrob Agents Chemother (2009) 1.80
Highly frequent mutations in negative regulators of multiple virulence genes in group A streptococcal toxic shock syndrome isolates. PLoS Pathog (2010) 1.77
Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition. Mol Cell Biol (2002) 1.77
Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease. Nat Immunol (2011) 1.76
DNA sequence analysis of DNA gyrase and DNA topoisomerase IV quinolone resistance-determining regions of Salmonella enterica serovar Typhi and serovar Paratyphi A. Antimicrob Agents Chemother (2002) 1.72
Positive effects of multiple pch genes on expression of the locus of enterocyte effacement genes and adherence of enterohaemorrhagic Escherichia coli O157 : H7 to HEp-2 cells. Microbiology (2004) 1.70
Silkworm larvae as an animal model of bacterial infection pathogenic to humans. Microb Pathog (2002) 1.69
Ceftriaxone-resistant Neisseria gonorrhoeae, Japan. Emerg Infect Dis (2011) 1.69
Vitamin C is dispensable for oxygen sensing in vivo. Blood (2011) 1.68
Vulnerable atherosclerotic plaque morphology in apolipoprotein E-deficient mice unable to make ascorbic Acid. Circulation (2002) 1.66
CCR5 deficiency is not protective in the early stages of atherogenesis in apoE knockout mice. Atherosclerosis (2003) 1.63
Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice. J Immunol (2002) 1.60
Comparison of the epidemiology of anti-neutrophil cytoplasmic antibody-associated vasculitis between Japan and the U.K. Rheumatology (Oxford) (2011) 1.59
Leptospiral immunoglobulin-like proteins elicit protective immunity. Vaccine (2004) 1.58
Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region. J RNAi Gene Silencing (2005) 1.57
Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. J Immunol (2007) 1.56
Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles. J Immunol (2004) 1.55
Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. Hypertension (2008) 1.55
Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system. Blood (2002) 1.54
Genes contributing to prion pathogenesis. J Gen Virol (2008) 1.51
Endogenous production of lipoic acid is essential for mouse development. Mol Cell Biol (2005) 1.49
Effects of calcineurin inhibitors on pharmacokinetics of mycophenolic acid and its glucuronide metabolite during the maintenance period following renal transplantation. Biol Pharm Bull (2006) 1.48
Hypersensitivity of nonhomologous DNA end-joining mutants to VP-16 and ICRF-193: implications for the repair of topoisomerase II-mediated DNA damage. J Biol Chem (2003) 1.47
Cholera between 1991 and 1997 in Mexico was associated with infection by classical, El Tor, and El Tor variants of Vibrio cholerae. J Clin Microbiol (2010) 1.47
Tissue inhibitor of metalloproteinase-3 deficiency inhibits blood pressure elevation and myocardial microvascular remodeling induced by chronic administration of Nomega-nitro-L-arginine methyl ester in mice. Hypertens Res (2007) 1.47
Autophagy proteins control goblet cell function by potentiating reactive oxygen species production. EMBO J (2013) 1.47
Diagnostic limitations to accurate diagnosis of cholera. J Clin Microbiol (2010) 1.43
MPO-ANCA induces IL-17 production by activated neutrophils in vitro via classical complement pathway-dependent manner. J Autoimmun (2008) 1.42
The value of power Doppler imaging to predict the histologic components of benign prostatic hyperplasia. Prostate (2002) 1.42
Applications of T-lymphoma labeled with fluorescent quantum dots to cell tracing markers in mouse body. Biochem Biophys Res Commun (2004) 1.41
Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates. J Hepatol (2005) 1.40
Seroprevalence of leptospirosis and risk factor analysis in flood-prone rural areas in Lao PDR. Am J Trop Med Hyg (2008) 1.39
Rac2 concentrations in umbilical cord neutrophils. Biol Neonate (2006) 1.39
EULAR points to consider in the development of classification and diagnostic criteria in systemic vasculitis. Ann Rheum Dis (2010) 1.38
Surgical outcome of laparoscopic radical prostatectomy: summary of early multiinstitutional experience in Japan. Int J Clin Oncol (2003) 1.38
Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors. J Clin Invest (2006) 1.38
BK virus nephropathy: clinical experience in a university hospital in Japan. Int J Urol (2009) 1.38
Saprobic potential of Tricholoma matsutake: growth over pine bark treated with surfactants. Mycorrhiza (2002) 1.38
Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions. J Immunol (2002) 1.37
Extensive genomic diversity and selective conservation of virulence-determinants in enterohemorrhagic Escherichia coli strains of O157 and non-O157 serotypes. Genome Biol (2007) 1.37
Bronchial casts and pandemic (H1N1) 2009 virus infection. Emerg Infect Dis (2010) 1.37
Severe diarrhea caused by cholera toxin-producing vibrio cholerae serogroup O75 infections acquired in the southeastern United States. Clin Infect Dis (2008) 1.36
Simple one-week method to construct gene-targeting vectors: application to production of human knockout cell lines. Biotechniques (2006) 1.36
Mutational analysis reveals distinct features of the Nox4-p22 phox complex. J Biol Chem (2008) 1.34
ClpXP protease controls expression of the type III protein secretion system through regulation of RpoS and GrlR levels in enterohemorrhagic Escherichia coli. J Bacteriol (2005) 1.34
Gene therapy of chronic granulomatous disease: the engraftment dilemma. Mol Ther (2010) 1.34
Multiplex polymerase chain reaction assay for selective detection of Salmonella enterica serovar typhimurium. Jpn J Infect Dis (2003) 1.33
Diffusion-weighted imaging of the liver: optimizing b value for the detection and characterization of benign and malignant hepatic lesions. J Magn Reson Imaging (2008) 1.32
Life-threatening infantile diarrhea from fluoroquinolone-resistant Salmonella enterica typhimurium with mutations in both gyrA and parC. Emerg Infect Dis (2003) 1.32
Human apoE4-targeted replacement mice display synaptic deficits in the absence of neuropathology. Neurobiol Dis (2005) 1.32
Dissemination of the phage-associated novel superantigen gene speL in recent invasive and noninvasive Streptococcus pyogenes M3/T3 isolates in Japan. Infect Immun (2002) 1.32
Loss of nonhomologous end joining confers camptothecin resistance in DT40 cells. Implications for the repair of topoisomerase I-mediated DNA damage. J Biol Chem (2004) 1.31
Minireview: estrogen and mouse models of atherosclerosis. Endocrinology (2002) 1.31
Multilocus variable-number tandem-repeat analysis for molecular typing of Shigella sonnei. J Clin Microbiol (2007) 1.30
Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation. Circulation (2009) 1.30
Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase. Proc Natl Acad Sci U S A (2011) 1.30
Integrated HIV DNA accumulates prior to treatment while episomal HIV DNA records ongoing transmission afterwards. AIDS (2012) 1.29
Interferon-γ production by neutrophils during bacterial pneumonia in mice. Am J Respir Crit Care Med (2010) 1.29
A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. BMC Med (2004) 1.28
Molecular evolutionary analysis of the influenza A(H1N1)pdm, May-September, 2009: temporal and spatial spreading profile of the viruses in Japan. PLoS One (2010) 1.28
Genetic evidence that the non-homologous end-joining repair pathway is involved in LINE retrotransposition. PLoS Genet (2009) 1.28
Utility of multilocus variable-number tandem-repeat analysis as a molecular tool for phylogenetic analysis of Shigella sonnei. J Clin Microbiol (2009) 1.27
Contributions from self-renewal and trafficking to the uterine NK cell population of early pregnancy. J Immunol (2002) 1.26
Gut microbiota of healthy and malnourished children in bangladesh. Front Microbiol (2011) 1.26
Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond. J Lipid Res (2008) 1.26
Spontaneous rupture of the urinary bladder presenting as oliguric acute renal failure. Intern Med (2006) 1.26
Rac2 is critical for neutrophil primary granule exocytosis. Blood (2004) 1.26
Genetic interactions between BLM and DNA ligase IV in human cells. J Biol Chem (2004) 1.25
Genotypic analyses of Vibrio parahaemolyticus and development of a pandemic group-specific multiplex PCR assay. J Clin Microbiol (2003) 1.24