Published in Mol Cell on June 01, 2002
Nature, nurture, or chance: stochastic gene expression and its consequences. Cell (2008) 12.13
The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation. Genes Dev (2006) 3.91
Multistable and multistep dynamics in neutrophil differentiation. BMC Cell Biol (2006) 1.56
Imaging gene expression in single living cells. Nat Rev Mol Cell Biol (2004) 1.39
In vivo live imaging of RNA polymerase II transcription factories in primary cells. Genes Dev (2013) 1.12
Exploring cellular memory molecules marking competent and active transcriptions. BMC Mol Biol (2007) 0.96
Fetal globin expression is regulated by Friend of Prmt1. Blood (2010) 0.94
Regulation of Ncx1 expression. Identification of regulatory elements mediating cardiac-specific expression and up-regulation. J Biol Chem (2006) 0.90
The epigenetic stability of the locus control region-deficient IgH locus in mouse hybridoma cells is a clonally varying, heritable feature. Genetics (2004) 0.88
A spatial point pattern analysis in Drosophila blastoderm embryos evaluating the potential inheritance of transcriptional states. PLoS One (2013) 0.83
Noise in multiple sclerosis: unwanted and necessary. Ann Clin Transl Neurol (2014) 0.75
The evolution of heterogeneities altered by mutational robustness, gene expression noise and bottlenecks in gene regulatory networks. PLoS One (2014) 0.75
Looping and interaction between hypersensitive sites in the active beta-globin locus. Mol Cell (2002) 11.35
CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes Dev (2006) 6.32
Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress. Circulation (2006) 5.58
The beta-globin nuclear compartment in development and erythroid differentiation. Nat Genet (2003) 5.54
Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). J Neurosci (2003) 4.72
Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice. Proc Natl Acad Sci U S A (2003) 4.28
The active spatial organization of the beta-globin locus requires the transcription factor EKLF. Genes Dev (2004) 4.04
Gene expression-based classification of non-small cell lung carcinomas and survival prediction. PLoS One (2010) 3.96
Spatial organization of gene expression: the active chromatin hub. Chromosome Res (2003) 3.91
CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. J Cell Biol (2005) 3.54
BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol (2012) 3.24
CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta. Dev Cell (2006) 2.99
RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation. Cell (2009) 2.76
Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. Nat Cell Biol (2002) 2.75
Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor. Mol Cell Proteomics (2007) 2.63
3C technology: analyzing the spatial organization of genomic loci in vivo. Methods Enzymol (2004) 2.58
GATA-1 forms distinct activating and repressive complexes in erythroid cells. EMBO J (2005) 2.56
Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin. Nat Genet (2010) 2.50
The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation. Genes Dev (2010) 2.47
Rab6 regulates transport and targeting of exocytotic carriers. Dev Cell (2007) 2.32
EB1 and EB3 control CLIP dissociation from the ends of growing microtubules. Mol Biol Cell (2005) 2.19
Multiple interactions between regulatory regions are required to stabilize an active chromatin hub. Genes Dev (2004) 2.17
NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment. Cell Stem Cell (2012) 2.15
GATA-3 promotes maturation, IFN-gamma production, and liver-specific homing of NK cells. Immunity (2003) 2.15
Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization. J Cell Biol (2004) 2.12
The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability. Mol Cell Biol (2005) 2.11
The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development. Genes Dev (2003) 2.10
Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation. Dev Biol (2008) 2.06
X inactivation counting and choice is a stochastic process: evidence for involvement of an X-linked activator. Cell (2008) 1.98
MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metab (2013) 1.87
Role of CLASP2 in microtubule stabilization and the regulation of persistent motility. Curr Biol (2006) 1.81
Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice. Nat Genet (2002) 1.81
ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis. Mol Cell Biol (2005) 1.70
Dynamic behavior of GFP-CLIP-170 reveals fast protein turnover on microtubule plus ends. J Cell Biol (2008) 1.68
Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. EMBO J (2003) 1.65
ETO2 coordinates cellular proliferation and differentiation during erythropoiesis. EMBO J (2006) 1.63
Novel binding partners of Ldb1 are required for haematopoietic development. Development (2006) 1.63
Erythropoiesis: model systems, molecular regulators, and developmental programs. IUBMB Life (2009) 1.61
The DNA-binding protein CTCF limits proximal Vκ recombination and restricts κ enhancer interactions to the immunoglobulin κ light chain locus. Immunity (2011) 1.57
CTCF regulates cell cycle progression of alphabeta T cells in the thymus. EMBO J (2008) 1.55
FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. J Cell Biol (2004) 1.51
Tissue-specific splicing factor gene expression signatures. Nucleic Acids Res (2008) 1.49
Multiplexed chromosome conformation capture sequencing for rapid genome-scale high-resolution detection of long-range chromatin interactions. Nat Protoc (2013) 1.46
Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis. Mol Cell (2012) 1.46
High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology. Nat Methods (2009) 1.44
Hypoxia inducible factor 3α plays a critical role in alveolarization and distal epithelial cell differentiation during mouse lung development. PLoS One (2013) 1.42
Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells. Mol Cell Biol (2011) 1.42
Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development. EMBO J (2011) 1.41
Beta-globin active chromatin Hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice. J Biol Chem (2007) 1.34
The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis. Genes Dev (2005) 1.33
Beta-globin regulation and long-range interactions. Adv Genet (2008) 1.31
Three-dimensional organization of gene expression in erythroid cells. Curr Top Dev Biol (2008) 1.30
Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts. Blood (2011) 1.28
Distal angiogenesis: a new concept for lung vascular morphogenesis. Am J Physiol Lung Cell Mol Physiol (2004) 1.28
Differential regulation of Foxo3a target genes in erythropoiesis. Mol Cell Biol (2007) 1.26
A generic tool for biotinylation of tagged proteins in transgenic mice. Transgenic Res (2005) 1.26
Functional and comparative analysis of globin loci in pufferfish and humans. Blood (2002) 1.23
Transcriptional dominance of Pax7 in adult myogenesis is due to high-affinity recognition of homeodomain motifs. Dev Cell (2012) 1.23
Inter-chromosomal gene regulation in the mammalian cell nucleus. Curr Opin Genet Dev (2007) 1.22
Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumors. Cancer Res (2003) 1.21
A tissue-specific knockout reveals that Gata1 is not essential for Sertoli cell function in the mouse. Nucleic Acids Res (2003) 1.20
Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice. PLoS Genet (2006) 1.19
Xist RNA is confined to the nuclear territory of the silenced X chromosome throughout the cell cycle. Mol Cell Biol (2008) 1.18
Increased risk of atherosclerosis by elevated plasma levels of phospholipid transfer protein. J Biol Chem (2002) 1.16
HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers. J Clin Invest (2014) 1.14
Critical role for the transcription regulator CCCTC-binding factor in the control of Th2 cytokine expression. J Immunol (2009) 1.14
A cell type-specific allele of the POU gene Oct-6 reveals Schwann cell autonomous function in nerve development and regeneration. EMBO J (2002) 1.13
A systems approach to analyze transcription factors in mammalian cells. Methods (2010) 1.10
Characterization of megakaryocyte GATA1-interacting proteins: the corepressor ETO2 and GATA1 interact to regulate terminal megakaryocyte maturation. Blood (2008) 1.06
CTCF regulates the local epigenetic state of ribosomal DNA repeats. Epigenetics Chromatin (2010) 1.06
Dynamic regulation of Gata factor levels is more important than their identity. Blood (2007) 1.06
Molecular mechanisms of pathology and treatment in Diamond Blackfan Anaemia. Br J Haematol (2012) 1.05
Retinoids and myelomonocytic growth factors cooperatively activate RARA and induce human myeloid leukemia cell differentiation via MAP kinase pathways. Blood (2004) 1.05
Elevation of systemic PLTP, but not macrophage-PLTP, impairs macrophage reverse cholesterol transport in transgenic mice. Atherosclerosis (2008) 1.05
EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence. Epigenetics Chromatin (2009) 1.05
History-dependent catastrophes regulate axonal microtubule behavior. Curr Biol (2010) 1.05
Transposition of the Drosophila hydei Minos transposon in the mouse germ line. Genomics (2003) 1.03
Mammalian Navigators are microtubule plus-end tracking proteins that can reorganize the cytoskeleton to induce neurite-like extensions. Cell Motil Cytoskeleton (2009) 1.03
Optimal use of tandem biotin and V5 tags in ChIP assays. BMC Mol Biol (2009) 1.02
The probability to initiate X chromosome inactivation is determined by the X to autosomal ratio and X chromosome specific allelic properties. PLoS One (2009) 1.02
DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia. Blood (2007) 1.01
Isolation and characterization of hematopoietic transcription factor complexes by in vivo biotinylation tagging and mass spectrometry. Ann N Y Acad Sci (2005) 1.00
Cell-nonautonomous function of the retinoblastoma tumour suppressor protein: new interpretations of old phenotypes. EMBO Rep (2002) 1.00
Ubiquitous expression of the rtTA2S-M2 inducible system in transgenic mice driven by the human hnRNPA2B1/CBX3 CpG island. BMC Dev Biol (2007) 1.00
Reduction of blood pressure, plasma cholesterol, and atherosclerosis by elevated endothelial nitric oxide. J Biol Chem (2002) 0.99
Impaired hematopoiesis in mice lacking the transcription factor Sp3. Blood (2003) 0.99
HS5 of the human beta-globin locus control region: a developmental stage-specific border in erythroid cells. EMBO J (2003) 0.99
Functional dissection of the Oct6 Schwann cell enhancer reveals an essential role for dimeric Sox10 binding. J Neurosci (2011) 0.99