Published in Epigenetics Chromatin on December 02, 2009
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Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell (2009) 5.51
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Essential role of the glycosyltransferase sxc/Ogt in polycomb repression. Science (2009) 3.44
Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma. Cancer Cell (2007) 3.14
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence. Genes Dev (2009) 3.04
Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus. Genes Dev (2009) 3.02
The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood (2005) 2.99
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Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS. Genes Dev (2009) 2.98
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Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus. PLoS One (2009) 1.47
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GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7. Mol Cell (2005) 2.21
Differential targeting of two distinct SWI/SNF-related Drosophila chromatin-remodeling complexes. Mol Cell Biol (2004) 2.18
SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus. Mol Cell Biol (2008) 2.14
The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability. Mol Cell Biol (2005) 2.11
Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4. Genes Dev (2012) 2.04
The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter. J Biol Chem (2006) 1.77
Pleiohomeotic can link polycomb to DNA and mediate transcriptional repression. Mol Cell Biol (2002) 1.74
Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing. Mol Cell (2009) 1.70
P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells. J Biol Chem (2003) 1.67
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Cancer-associated mutations in chromatin remodeler hSNF5 promote chromosomal instability by compromising the mitotic checkpoint. Genes Dev (2005) 1.61
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Synergistic recognition of an epigenetic DNA element by Pleiohomeotic and a Polycomb core complex. Genes Dev (2005) 1.52
FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. J Cell Biol (2004) 1.51
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GAGA can mediate enhancer function in trans by linking two separate DNA molecules. EMBO J (2002) 1.40
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DNA looping induced by a transcriptional enhancer in vivo. Nucleic Acids Res (2005) 1.32
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The transcriptional coactivator SAYP is a trithorax group signature subunit of the PBAP chromatin remodeling complex. Mol Cell Biol (2008) 1.23
Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumors. Cancer Res (2003) 1.21
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The cypriot and Iranian National Mutation Frequency Databases. Hum Mutat (2006) 1.08
Dynamic regulation of Gata factor levels is more important than their identity. Blood (2007) 1.06
Molecular mechanisms of pathology and treatment in Diamond Blackfan Anaemia. Br J Haematol (2012) 1.05
Retinoids and myelomonocytic growth factors cooperatively activate RARA and induce human myeloid leukemia cell differentiation via MAP kinase pathways. Blood (2004) 1.05
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RTTN mutations link primary cilia function to organization of the human cerebral cortex. Am J Hum Genet (2012) 1.01
Metabolic enzyme IMPDH is also a transcription factor regulated by cellular state. Mol Cell (2012) 1.01
DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia. Blood (2007) 1.01
Isolation and characterization of hematopoietic transcription factor complexes by in vivo biotinylation tagging and mass spectrometry. Ann N Y Acad Sci (2005) 1.00
Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation. Mol Cell Proteomics (2012) 0.97
Drosophila transcription factor Tramtrack69 binds MEP1 to recruit the chromatin remodeler NuRD. Mol Cell Biol (2010) 0.97
Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors. Blood (2004) 0.96
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Fetal globin expression is regulated by Friend of Prmt1. Blood (2010) 0.94
Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice. Blood (2013) 0.94
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Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors. J Exp Med (2004) 0.93
Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype. Blood (2010) 0.92
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MLL-ENL cooperates with SCF to transform primary avian multipotent cells. EMBO J (2002) 0.91
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Immuno-depletion and purification strategies to study chromatin-remodeling factors in vitro. Methods Enzymol (2004) 0.91
Hydroxyurea responsiveness in β-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity. Haematologica (2012) 0.91
The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity. Biol Chem (2004) 0.90
Igbp1 is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation. Blood (2008) 0.90
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Gene expression control by protein deubiquitinases. Curr Opin Genet Dev (2011) 0.88
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Locus-specific proteomics by TChP: targeted chromatin purification. Cell Rep (2013) 0.87
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Histone chaperone NAP1 mediates sister chromatid resolution by counteracting protein phosphatase 2A. PLoS Genet (2013) 0.82
KLF10 gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients. Pharmacogenomics (2012) 0.81
Molecular biology. A higher order of silence. Science (2004) 0.80
The role of translation initiation regulation in haematopoiesis. Comp Funct Genomics (2012) 0.79
Abnormal properties of red blood cells suggest a role in the pathophysiology of Gaucher disease. Blood (2012) 0.79
The DNA binding factor Hmg20b is a repressor of erythroid differentiation. Haematologica (2011) 0.78
The Hellenic type of nondeletional hereditary persistence of fetal hemoglobin results from a novel mutation (g.-109G>T) in the HBG2 gene promoter. Ann Hematol (2008) 0.78
Loss of ercc1 results in a time- and dose-dependent reduction of proliferating early hematopoietic progenitors. Anemia (2012) 0.77
Screening of Iranian thalassemic families for the most common deletions of the beta-globin gene cluster. Hemoglobin (2007) 0.75