Published in Nat Rev Neurosci on July 01, 2002
Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells (2005) 3.38
Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using the bone morphogenic protein antagonist noggin. Stem Cells (2006) 2.37
Illumination controls differentiation of dopamine neurons regulating behaviour. Nature (2008) 2.06
The brainstem and serotonin in the sudden infant death syndrome. Annu Rev Pathol (2009) 2.03
Maternal serotonin is crucial for murine embryonic development. Proc Natl Acad Sci U S A (2006) 1.75
Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem. J Neurosci (2010) 1.57
Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation. Stem Cells (2005) 1.56
Genetic networks controlling the development of midbrain dopaminergic neurons. J Physiol (2006) 1.41
1-methyl-4-phenylpyridinium stereotactic infusion completely and specifically ablated the nigrostriatal dopaminergic pathway in rhesus macaque. PLoS One (2015) 1.38
Development of enteric neuron diversity. J Cell Mol Med (2009) 1.31
Cell replacement therapy in neurological disease. Philos Trans R Soc Lond B Biol Sci (2006) 1.29
p57(Kip2) cooperates with Nurr1 in developing dopamine cells. Proc Natl Acad Sci U S A (2003) 1.28
Serotonergic transcriptional networks and potential importance to mental health. Nat Neurosci (2012) 1.28
Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system. Dev Biol (2007) 1.26
Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system. Development (2010) 1.22
Stromal cell-derived inducing activity, Nurr1, and signaling molecules synergistically induce dopaminergic neurons from mouse embryonic stem cells. Stem Cells (2005) 1.22
Dicer is required for survival of differentiating neural crest cells. Dev Biol (2010) 1.19
Abnormal sympathetic nervous system development and physiological dysautonomia in Egr3-deficient mice. Development (2008) 1.19
Developmental origins of central norepinephrine neuron diversity. Nat Neurosci (2013) 1.19
Parkinson's disease-related protein, alpha-synuclein, in malignant melanoma. PLoS One (2010) 1.17
Transcriptional regulation of neuronal phenotype in mammals. J Physiol (2006) 1.12
Structure, expression, and biological function of INSM1 transcription factor in neuroendocrine differentiation. FASEB J (2009) 1.10
Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception. Genes Dev (2005) 1.10
A sympathetic neuron autonomous role for Egr3-mediated gene regulation in dendrite morphogenesis and target tissue innervation. J Neurosci (2013) 1.08
MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development. Am J Pathol (2009) 1.08
The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors. J Neurosci (2013) 1.05
Human embryonic stem cells for brain repair? Philos Trans R Soc Lond B Biol Sci (2008) 1.04
Neurogenin1 is a determinant of zebrafish basal forebrain dopaminergic neurons and is regulated by the conserved zinc finger protein Tof/Fezl. Proc Natl Acad Sci U S A (2006) 1.02
Differential regulation of the zebrafish orthopedia 1 gene during fate determination of diencephalic neurons. BMC Dev Biol (2006) 1.00
Hedgehog and Fgf signaling pathways regulate the development of tphR-expressing serotonergic raphe neurons in zebrafish embryos. J Neurobiol (2004) 1.00
The role of GDNF family ligand signalling in the differentiation of sympathetic and dorsal root ganglion neurons. Cell Tissue Res (2008) 0.99
Generation of diverse neuronal subtypes in cloned populations of stem-like cells. BMC Dev Biol (2008) 0.99
The bHLH transcription factor Hand2 is essential for the maintenance of noradrenergic properties in differentiated sympathetic neurons. Dev Biol (2009) 0.99
Bone morphogenetic protein 9 induces the transcriptome of basal forebrain cholinergic neurons. Proc Natl Acad Sci U S A (2005) 0.99
Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain. Development (2009) 0.98
Roles of db-cAMP, IBMX and RA in aspects of neural differentiation of cord blood derived mesenchymal-like stem cells. PLoS One (2010) 0.96
Generation of serotonin neurons from human pluripotent stem cells. Nat Biotechnol (2015) 0.95
Serotonergic neurons migrate radially through the neuroepithelium by dynamin-mediated somal translocation. J Neurosci (2010) 0.94
Homeodomain transcription factor Phox2a, via cyclic AMP-mediated activation, induces p27Kip1 transcription, coordinating neural progenitor cell cycle exit and differentiation. Mol Cell Biol (2006) 0.93
Gestational exposure to the organophosphate chlorpyrifos alters social-emotional behaviour and impairs responsiveness to the serotonin transporter inhibitor fluvoxamine in mice. Psychopharmacology (Berl) (2009) 0.92
Biology of Parkinson's disease: pathogenesis and pathophysiology of a multisystem neurodegenerative disorder. Dialogues Clin Neurosci (2004) 0.90
Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma. BMC Mol Biol (2009) 0.89
Distinct neuroblastoma-associated alterations of PHOX2B impair sympathetic neuronal differentiation in zebrafish models. PLoS Genet (2013) 0.88
Subset specification of central serotonergic neurons. Front Cell Neurosci (2013) 0.88
Molecular underpinnings of prefrontal cortex development in rodents provide insights into the etiology of neurodevelopmental disorders. Mol Psychiatry (2014) 0.87
atonal- and achaete-scute-related genes in the annelid Platynereis dumerilii: insights into the evolution of neural basic-Helix-Loop-Helix genes. BMC Evol Biol (2008) 0.87
Crucial role of zebrafish prox1 in hypothalamic catecholaminergic neurons development. BMC Dev Biol (2008) 0.87
Trim11 increases expression of dopamine beta-hydroxylase gene by interacting with Phox2b. Biochem Biophys Res Commun (2008) 0.87
Serotonergic 5-HT(2B) receptor controls tissue-nonspecific alkaline phosphatase activity in osteoblasts via eicosanoids and phosphatidylinositol-specific phospholipase C. J Biol Chem (2010) 0.86
Expression profile of differentiating serotonin neurons derived from rhesus embryonic stem cells and comparison to adult serotonin neurons. Gene Expr Patterns (2008) 0.86
Frizzled3 is required for neurogenesis and target innervation during sympathetic nervous system development. J Neurosci (2011) 0.86
The transcription factor Hmx1 and growth factor receptor activities control sympathetic neurons diversification. EMBO J (2013) 0.85
The basic helix-loop-helix factor Hand 2 regulates autonomic nervous system development. Dev Dyn (2005) 0.85
Cytokines inhibit norepinephrine transporter expression by decreasing Hand2. Mol Cell Neurosci (2011) 0.85
Regulation of the noradrenaline neurotransmitter phenotype by the transcription factor AP-2beta. J Biol Chem (2008) 0.85
SoxE proteins are differentially required in mouse adrenal gland development. Mol Biol Cell (2008) 0.85
Postnatal maintenance of the 5-Ht1a-Pet1 autoregulatory loop by serotonin in the raphe nuclei of the brainstem. Mol Brain (2014) 0.84
HOXC9 directly regulates distinct sets of genes to coordinate diverse cellular processes during neuronal differentiation. BMC Genomics (2013) 0.84
Transcriptional profiling of fetal hypothalamic TRH neurons. BMC Genomics (2011) 0.83
High-level activation of cyclic AMP signaling attenuates bone morphogenetic protein 2-induced sympathoadrenal lineage development and promotes melanogenesis in neural crest cultures. Mol Cell Biol (2005) 0.83
Genetic dissection of midbrain dopamine neuron development in vivo. Dev Biol (2012) 0.83
Transcription factor GATA-3 regulates the transcriptional activity of dopamine beta-hydroxylase by interacting with Sp1 and AP4. Neurochem Res (2008) 0.83
Non-traditional cytokines: How catecholamines and adipokines influence macrophages in immunity, metabolism and the central nervous system. Cytokine (2015) 0.82
A neurochemical map of the developing amphioxus nervous system. BMC Neurosci (2012) 0.81
In vivo calcium dynamics during neural crest cell migration and patterning using GCaMP3. Dev Biol (2011) 0.81
Prenatal Cocaine Disrupts Serotonin Signaling-Dependent Behaviors: Implications for Sex Differences, Early Stress and Prenatal SSRI Exposure. Curr Neuropharmacol (2011) 0.81
Asymmetric cell division and Notch signaling specify dopaminergic neurons in Drosophila. PLoS One (2011) 0.80
Age-associated changes in mRNA levels of Phox2, norepinephrine transporter and dopamine beta-hydroxylase in the locus coeruleus and adrenal glands of rats. J Neurochem (2005) 0.80
Engrailed-2 (En2) deletion produces multiple neurodevelopmental defects in monoamine systems, forebrain structures and neurogenesis and behavior. Hum Mol Genet (2015) 0.79
Reserve pool neuron transmitter respecification: Novel neuroplasticity. Dev Neurobiol (2012) 0.79
Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development. Neural Dev (2008) 0.79
Generation of murine sympathoadrenergic progenitor-like cells from embryonic stem cells and postnatal adrenal glands. PLoS One (2013) 0.79
Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes. Stem Cell Reports (2015) 0.79
The emerging role of GATA transcription factors in development and disease. Expert Rev Mol Med (2016) 0.79
Egr3 dependent sympathetic target tissue innervation in the absence of neuron death. PLoS One (2011) 0.78
Reconstruction of the gene regulatory network involved in the sonic hedgehog pathway with a potential role in early development of the mouse brain. PLoS Comput Biol (2014) 0.78
Transcription factor Phox2 upregulates expression of norepinephrine transporter and dopamine β-hydroxylase in adult rat brains. Neuroscience (2011) 0.78
Phospho-mTOR is not upregulated in metastatic SDHB paragangliomas. Eur J Clin Invest (2013) 0.78
Restriction of neural precursor ability to respond to Nurr1 by early regional specification. PLoS One (2012) 0.78
Sim1 is a novel regulator in the differentiation of mouse dorsal raphe serotonergic neurons. PLoS One (2011) 0.78
Developmental expression of tryptophan hydroxylase gene in Ciona intestinalis. Dev Genes Evol (2007) 0.77
Characterization of primary neurospheres generated from mouse ventral rostral hindbrain. Cell Tissue Res (2009) 0.77
Transcription factor AP-2β regulates the neurotransmitter phenotype and maturation of chromaffin cells. Mol Cell Neurosci (2010) 0.77
Ascl1 as a novel player in the Ptf1a transcriptional network for GABAergic cell specification in the retina. PLoS One (2014) 0.76
Nucleotide sequence conservation of novel and established cis-regulatory sites within the tyrosine hydroxylase gene promoter. Front Biol (Beijing) (2015) 0.76
Histamine impairs midbrain dopaminergic development in vivo by activating histamine type 1 receptors. Mol Brain (2014) 0.76
Proceedings of the fourth international conference on central hypoventilation. Orphanet J Rare Dis (2014) 0.75
The Role of Serotonin beyond the Central Nervous System during Embryogenesis. Front Cell Neurosci (2017) 0.75
Crosstalk among electrical activity, trophic factors and morphogenetic proteins in the regulation of neurotransmitter phenotype specification. J Chem Neuroanat (2015) 0.75
Timing the Phox-trot: duration of Phox2a-dependent transcription is controlled by an intramolecular dephosphorylation/phosphorylation clock. Mol Cell Biol (2009) 0.75
PHOX2A and PHOX2B are differentially regulated during retinoic acid-driven differentiation of SK-N-BE(2)C neuroblastoma cell line. Exp Cell Res (2016) 0.75
Cell-Autonomous Gβ Signaling Defines Neuron-Specific Steady State Serotonin Synthesis in Caenorhabditis elegans. PLoS Genet (2015) 0.75
Recovery of network-driven glutamatergic activity in rat hippocampal neurons during chronic glutamate receptor blockade. Brain Res (2008) 0.75
Transcriptional Profiling Reveals a Common Metabolic Program in High-Risk Human Neuroblastoma and Mouse Neuroblastoma Sphere-Forming Cells. Cell Rep (2016) 0.75
Effects of Simazine Exposure on Neuronal Development-Related Factors in MN9D Cells. Med Sci Monit (2016) 0.75
Characterization of Induced Pluripotent Stem Cell-derived Human Serotonergic Neurons. Front Cell Neurosci (2017) 0.75
Embryonic development of selectively vulnerable neurons in Parkinson's disease. NPJ Parkinsons Dis (2017) 0.75
Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration. PLoS One (2009) 1.71
Essential role of Gata transcription factors in sympathetic neuron development. Development (2004) 1.45
Target-dependent specification of the neurotransmitter phenotype: cholinergic differentiation of sympathetic neurons is mediated in vivo by gp 130 signaling. Development (2005) 1.44
Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo. Development (2007) 1.28
The bHLH transcription factor hand2 is essential for noradrenergic differentiation of sympathetic neurons. Development (2006) 1.25
Prox1 regulates the notch1-mediated inhibition of neurogenesis. PLoS Biol (2010) 1.23
Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system. Development (2010) 1.22
Immunolocalization of ciliary neurotrophic factor receptor alpha (CNTFRalpha) in mammalian photoreceptor cells. Mol Vis (2005) 1.14
The dependence on gp130 cytokines of axotomy induced neuropeptide expression in adult sympathetic neurons. Dev Neurobiol (2009) 1.05
Midkine and Alk signaling in sympathetic neuron proliferation and neuroblastoma predisposition. Development (2011) 1.05
Progenitor cell maintenance and neurogenesis in sympathetic ganglia involves Notch signaling. Mol Cell Neurosci (2007) 1.01
Neuroblastoma phox2b variants stimulate proliferation and dedifferentiation of immature sympathetic neurons. J Neurosci (2010) 1.00
Infarction-induced cytokines cause local depletion of tyrosine hydroxylase in cardiac sympathetic nerves. Exp Physiol (2009) 0.99
The bHLH transcription factor Hand2 is essential for the maintenance of noradrenergic properties in differentiated sympathetic neurons. Dev Biol (2009) 0.99
The Gata3 transcription factor is required for the survival of embryonic and adult sympathetic neurons. J Neurosci (2010) 0.95
Molecular control of ciliary neuron development: BMPs and downstream transcriptional control in the parasympathetic lineage. Development (2002) 0.93
Cloning, mapping, and retinal expression of the canine ciliary neurotrophic factor receptor alpha (CNTFRalpha). Invest Ophthalmol Vis Sci (2003) 0.93
Absence of gp130 in dopamine beta-hydroxylase-expressing neurons leads to autonomic imbalance and increased reperfusion arrhythmias. Am J Physiol Heart Circ Physiol (2009) 0.90
Impaired autonomic regulation of resistance arteries in mice with low vascular endothelial growth factor or upon vascular endothelial growth factor trap delivery. Circulation (2010) 0.90
Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma. Oncotarget (2014) 0.89
BM88/CEND1 coordinates cell cycle exit and differentiation of neuronal precursors. Proc Natl Acad Sci U S A (2007) 0.86
HAND transcription factors are required for neonatal sympathetic neuron survival. EMBO Rep (2008) 0.86
The transcription factors AP-2β and AP-2α are required for survival of sympathetic progenitors and differentiated sympathetic neurons. Dev Biol (2011) 0.84
The specification of noradrenergic locus coeruleus (LC) neurones depends on bone morphogenetic proteins (BMPs). Development (2002) 0.83
Interaction of Mash1 and Phox2b in sympathetic neuron development. Mol Cell Neurosci (2004) 0.81
Expression pattern of BM88 in the developing nervous system of the chick and mouse embryo. Gene Expr Patterns (2006) 0.80
Peripheral nervous system progenitors can be reprogrammed to produce myelinating oligodendrocytes and repair brain lesions. J Neurosci (2011) 0.80
Generation of the tamoxifen-inducible DBH-Cre transgenic mouse line DBH-CT. Genesis (2011) 0.80
A function for the calponin family member NP25 in neurite outgrowth. Dev Biol (2008) 0.80
Dendrite complexity of sympathetic neurons is controlled during postnatal development by BMP signaling. J Neurosci (2013) 0.79
HoxB8 in noradrenergic specification and differentiation of the autonomic nervous system. Dev Biol (2011) 0.79
Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development. Neural Dev (2008) 0.79
The developmental expression of vasoactive intestinal peptide (VIP) in cholinergic sympathetic neurons depends on cytokines signaling through LIFRbeta-containing receptors. Development (2002) 0.78
Development of the autonomic nervous system: New perspectives and open questions. Auton Neurosci (2009) 0.78
In vivo role for CREB signaling in the noradrenergic differentiation of sympathetic neurons. Mol Cell Neurosci (2009) 0.78
The cortistatin gene PSS2 rather than the somatostatin gene PSS1 is strongly expressed in developing avian autonomic neurons. J Comp Neurol (2010) 0.77
Alternative generation of CNS neural stem cells and PNS derivatives from neural crest-derived peripheral stem cells. Stem Cells (2015) 0.75
Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev (2013) 0.75