Published in J Eukaryot Microbiol on July 03, 2002
The state of the art of the zebrafish model for toxicology and toxicologic pathology research--advantages and current limitations. Toxicol Pathol (2003) 1.79
Recommendations for control of pathogens and infectious diseases in fish research facilities. Comp Biochem Physiol C Toxicol Pharmacol (2008) 1.66
Pseudoloma neurophilia infections in zebrafish Danio rerio: effects of stress on survival, growth, and reproduction. Dis Aquat Organ (2009) 1.61
Documented and potential research impacts of subclinical diseases in zebrafish. ILAR J (2012) 1.43
Polymerase chain reaction detection of Pseudoloma neurophilia, a common microsporidian of zebrafish (Danio rerio) reared in research laboratories. J Am Assoc Lab Anim Sci (2006) 1.31
Luna stain, an improved selective stain for detection of microsporidian spores in histologic sections. Dis Aquat Organ (2011) 1.30
Pleistophora hyphessobryconis (Microsporidia) infecting zebrafish Danio rerio in research facilities. Dis Aquat Organ (2010) 1.27
Transmission, diagnosis, and recommendations for control of Pseudoloma neurophilia infections in laboratory zebrafish (Danio rerio) facilities. Comp Med (2011) 1.23
Verification of intraovum transmission of a microsporidium of vertebrates: Pseudoloma neurophilia infecting the Zebrafish, Danio rerio. PLoS One (2013) 1.16
Microsporidiosis in zebrafish research facilities. ILAR J (2012) 1.11
Husbandry stress exacerbates mycobacterial infections in adult zebrafish, Danio rerio (Hamilton). J Fish Dis (2009) 1.08
Development of a sensitive assay for the detection of Pseudoloma neurophilia in laboratory populations of the zebrafish Danio rerio. Dis Aquat Organ (2011) 1.04
New models of microsporidiosis: infections in Zebrafish, C. elegans, and honey bee. PLoS Pathog (2011) 1.03
The challenges of implementing pathogen control strategies for fishes used in biomedical research. Comp Biochem Physiol C Toxicol Pharmacol (2011) 1.01
Morphological and molecular biological characterization of Pleistophora aegyptiaca sp. nov. infecting the Red Sea fish Saurida tumbil. Parasitol Res (2011) 0.99
Ultrastructure and molecular phylogenetics of a new isolate of Pleistophora pagri sp. nov. (Microsporidia, Pleistophoridae) from Pagrus pagrus in Egypt. Parasitol Res (2012) 0.93
Development, ultrastructural pathology, and taxonomic revision of the Microsporidial genus, Pseudoloma and its type species Pseudoloma neurophilia, in skeletal muscle and nervous tissue of experimentally infected zebrafish Danio rerio. J Eukaryot Microbiol (2011) 0.91
Morphological and genetical description of Loma psittaca sp. n. isolated from the Amazonian fish species Colomesus psittacus. Parasitol Res (2009) 0.90
Early development and tissue distribution of Pseudoloma neurophilia in the zebrafish, Danio rerio. J Eukaryot Microbiol (2014) 0.84
Pseudoloma neurophilia: a retrospective and descriptive study of nervous system and muscle infections, with new implications for pathogenesis and behavioral phenotypes. Zebrafish (2015) 0.84
Utilization of zebrafish for intravital study of eukaryotic pathogen-host interactions. Dev Comp Immunol (2014) 0.82
Pathology in practice. P tomentosa infection in zebrafish. J Am Vet Med Assoc (2015) 0.82
Controlling Endemic Pathogens-Challenges and Opportunities. Zebrafish (2016) 0.78
Expansion of the Known Host Range of the Microsporidium, Pseudoloma neurophilia. Zebrafish (2016) 0.77
Genome Analysis of Pseudoloma neurophilia: A Microsporidian Parasite of Zebrafish (Danio rerio). J Eukaryot Microbiol (2016) 0.75
Randomised controlled trial of nasal ventilation in acute ventilatory failure due to chronic obstructive airways disease. Lancet (1993) 5.43
The calcium current of Helix neuron. J Gen Physiol (1978) 5.18
Spermine and spermidine as gating molecules for inward rectifier K+ channels. Science (1994) 4.82
Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy. Circulation (1995) 4.48
Short-course empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit. A proposed solution for indiscriminate antibiotic prescription. Am J Respir Crit Care Med (2000) 4.21
A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning. Nature (1989) 3.99
In vivo growth characteristics of leucine and methionine auxotrophic mutants of Mycobacterium bovis BCG generated by transposon mutagenesis. Infect Immun (1995) 3.56
The future of general practice in Newcastle upon Tyne. Lancet (1986) 3.47
Properties of internally perfused, voltage-clamped, isolated nerve cell bodies. J Gen Physiol (1978) 3.44
Receptor-effector coupling by G proteins. Biochim Biophys Acta (1990) 3.31
Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7. Proc Natl Acad Sci U S A (1984) 3.25
Calcium current-dependent and voltage-dependent inactivation of calcium channels in Helix aspersa. J Physiol (1981) 3.23
Exchange of conduction pathways between two related K+ channels. Science (1991) 3.09
Validity of clinical examination and mammography as screening tests for breast cancer. Lancet (1975) 2.95
Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. J Cell Biol (1993) 2.95
Cardiac Na currents and the inactivating, reopening, and waiting properties of single cardiac Na channels. J Gen Physiol (1985) 2.93
Gating of inwardly rectifying K+ channels localized to a single negatively charged residue. Nature (1994) 2.91
A physical and genetic map of the IncN plasmid R46. Plasmid (1981) 2.86
Sodium current in single rat heart muscle cells. J Physiol (1981) 2.83
Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family. J Med Genet (2000) 2.82
A massive phytoplankton bloom induced by an ecosystem-scale iron fertilization experiment in the equatorial Pacific Ocean. Nature (1996) 2.75
Transformation by Wnt family proteins correlates with regulation of beta-catenin. Cell Growth Differ (1997) 2.74
Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis. J Exp Med (1997) 2.59
A G protein directly regulates mammalian cardiac calcium channels. Science (1987) 2.58
Interprofessional collaboration in primary health care. J R Coll Gen Pract (1987) 2.56
Evidence for high-energy extraterrestrial neutrinos at the IceCube detector. Science (2013) 2.56
Heterologous regulation of the cardiac Ca2+ channel alpha 1 subunit by skeletal muscle beta and gamma subunits. Implications for the structure of cardiac L-type Ca2+ channels. J Biol Chem (1991) 2.55
Note on the nitrogen content of certain proteins. Biochem J (1932) 2.54
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension. Am J Hum Genet (2000) 2.51
Direct activation of mammalian atrial muscarinic potassium channels by GTP regulatory protein Gk. Science (1987) 2.50
Interactions of the 5-hydroxytryptamine 3 antagonist class of antiemetic drugs with human cardiac ion channels. J Pharmacol Exp Ther (2000) 2.47
HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine. Circulation (1996) 2.46
Early outward current in rat single ventricular cells. Circ Res (1984) 2.41
Inactivation determined by a single site in K+ pores. Pflugers Arch (1993) 2.37
The relationship of HIV prevalence in pregnant women to that in women of reproductive age: a validated method for adjustment. AIDS (1998) 2.34
A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line. Cell (1986) 2.32
Multiple mechanisms of Na+ channel--linked long-QT syndrome. Circ Res (1996) 2.29
Alteration and restoration of K+ channel function by deletions at the N- and C-termini. Neuron (1990) 2.26
The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix. EMBO J (1990) 2.25
A multicentre randomized controlled trial of epidural corticosteroid injections for sciatica: the WEST study. Rheumatology (Oxford) (2005) 2.23
Sodium current in single heart muscle cells. Nature (1979) 2.19
Canavanine death in Escherichia coli. J Mol Biol (1965) 2.19
Patch and whole cell calcium currents recorded simultaneously in snail neurons. J Gen Physiol (1984) 2.17
Molecular determinants of dofetilide block of HERG K+ channels. Circ Res (1998) 2.13
Prognosis in the irritable bowel syndrome: a 5-year prospective study. Lancet (1987) 2.13
A comparison of calcium currents in rat and guinea pig single ventricular cells. Circ Res (1984) 2.12
Increased chloride conductance as the proximate cause of hydrogen ion concentration effects in Aplysia neurons. J Gen Physiol (1970) 2.09
Normalization of current kinetics by interaction between the alpha 1 and beta subunits of the skeletal muscle dihydropyridine-sensitive Ca2+ channel. Nature (1991) 2.09
GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents. Science (1992) 2.09
The agonist effect of dihydropyridines on Ca channels. Nature (1984) 2.07
Induction of calcium currents by the expression of the alpha 1-subunit of the dihydropyridine receptor from skeletal muscle. Nature (1989) 2.04
Variable participation of 5-HT1-like receptors and 5-HT2 receptors in serotonin-induced contraction of human isolated coronary arteries. 5-HT1-like receptors resemble cloned 5-HT1D beta receptors. Circulation (1994) 2.02
Identity of a novel delayed rectifier current from human heart with a cloned K+ channel current. Circ Res (1993) 2.02
Similarity of unitary Ca2+ currents in three different species. Nature (1982) 2.00
Scanning calorimetric study of the thermal unfolding of catabolite activator protein from Escherichia coli in the absence and presence of cyclic mononucleotides. Biochemistry (1988) 2.00
First observation of PeV-energy neutrinos with IceCube. Phys Rev Lett (2013) 2.00
Light response of a giant Aplysia neuron. J Gen Physiol (1973) 1.96
A description of activation and conduction in calcium channels based on tail and turn-on current measurements in the snail. J Physiol (1983) 1.93
A population-based study of prostate cancer chemotherapy. Clin Oncol (R Coll Radiol) (2011) 1.92
K+ pore structure revealed by reporter cysteines at inner and outer surfaces. Neuron (1995) 1.91
Leucine auxotrophy restricts growth of Mycobacterium bovis BCG in macrophages. Infect Immun (1996) 1.89
Wnt-1 regulation of connexin43 in cardiac myocytes. J Clin Invest (2000) 1.87
Specification of pore properties by the carboxyl terminus of inwardly rectifying K+ channels. Science (1994) 1.85
Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene. Mol Cell Biol (1985) 1.85
Relapsing experimental allergic encephalomyelitis in the SJL/J mouse. Lab Invest (1981) 1.84
Unified account of the variable effects of carbon dioxide on nerve cells. Science (1970) 1.84
C-terminus determinants for Mg2+ and polyamine block of the inward rectifier K+ channel IRK1. EMBO J (1995) 1.84
Discovery of very-high-energy gamma-rays from the Galactic Centre ridge. Nature (2006) 1.81
Evidence for a direct effect of alcohol consumption on blood pressure in normotensive men. A randomized controlled trial. Hypertension (1985) 1.81
The alpha subunit of the GTP binding protein Gk opens atrial potassium channels. Science (1987) 1.79
Coupling of ATP-sensitive K+ channels to A1 receptors by G proteins in rat ventricular myocytes. Am J Physiol (1990) 1.79
The units of calcium conduction in Helix neurones. Nature (1978) 1.78
Epidemiology of genital Chlamydia trachomatis in England and Wales. Genitourin Med (1997) 1.78
From naive to memory T cells. Immunol Rev (1996) 1.76
Interaction between calcium ions and surface charge as it relates to calcium currents. J Membr Biol (1983) 1.76
Nonmodal gating of cardiac calcium channels as revealed by dihydropyridines. J Gen Physiol (1989) 1.76
SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. Neuropharmacology (1997) 1.76
A 5-hydroxytryptamine receptor in human atrium. Br J Pharmacol (1990) 1.76
The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells. Mol Cell Biol (1992) 1.75
Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias. J Cardiovasc Electrophysiol (2000) 1.74
KChAP as a chaperone for specific K(+) channels. Am J Physiol Cell Physiol (2000) 1.73
Fast and slow gating of sodium channels encoded by a single mRNA. Neuron (1990) 1.71
Electrocardiographic prediction of abnormal genotype in congenital long QT syndrome: experience in 101 related family members. J Cardiovasc Electrophysiol (2001) 1.71
Patterns of internal and external tetraethylammonium block in four homologous K+ channels. Mol Pharmacol (1991) 1.71
Structure of the human oestrogen-responsive gene pS2. Nucleic Acids Res (1987) 1.70
Two nonredundant SecA homologues function in mycobacteria. J Bacteriol (2001) 1.69
Differences between the deep pores of K+ channels determined by an interacting pair of nonpolar amino acids. Neuron (1992) 1.69
ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels. Cell (1990) 1.67
Rapid beta-adrenergic modulation of cardiac calcium channel currents by a fast G protein pathway. Science (1989) 1.66
The suction pipette method for internal perfusion and voltage clamp of small excitable cells. J Neurosci Methods (1980) 1.64
Whole-cell and single-channel calcium currents of isolated smooth muscle cells from saphenous vein. Circ Res (1987) 1.63
Signal transduction of gamma/delta T cell antigen receptor with a novel mitogenic anti-delta antibody. J Immunol (1988) 1.62
Trypsin inhibits the action of tetrodotoxin on neurones. Nature (1977) 1.61
Complete surgical excision is effective treatment for children with immature teratomas with or without malignant elements: A Pediatric Oncology Group/Children's Cancer Group Intergroup Study. J Clin Oncol (1999) 1.61
Targeted deletion of the IgA constant region in mice leads to IgA deficiency with alterations in expression of other Ig isotypes. J Immunol (1999) 1.61
Cyclooxygenase-2: a target for the prevention and treatment of breast cancer. Endocr Relat Cancer (2001) 1.61
The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway. Mol Cell Biol (1987) 1.60