Published in Plasmid on March 01, 1981
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Rapid procedure for isolation of plasmid DNA and application to epidemiological analysis. J Clin Microbiol (1984) 5.09
Processing of plasmid DNA during bacterial conjugation. Microbiol Rev (1984) 4.83
Identification and classification of bacterial plasmids. Microbiol Rev (1988) 4.16
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Conjugal transfer system of the IncN plasmid pKM101. J Bacteriol (1985) 3.03
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Family of class 1 integrons related to In4 from Tn1696. Antimicrob Agents Chemother (2001) 2.41
Identification of pKM101-encoded loci specifying potentially lethal gene products. J Bacteriol (1985) 2.00
Expression of a Thiobacillus ferrooxidans origin of replication in Escherichia coli. J Bacteriol (1984) 1.88
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Entry exclusion determinant(s) of IncN plasmid pKM101. J Bacteriol (1985) 1.71
Genetic localization and characterization of a pKM101-coded endonuclease. J Bacteriol (1983) 1.70
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Development of natural and synthetic DNA probes for OXA-2 and TEM-1 beta-lactamases. Antimicrob Agents Chemother (1987) 1.32
A gene probe for TEM type beta-lactamases. Antimicrob Agents Chemother (1985) 1.32
Characterization of IS46, an insertion sequence found on two IncN plasmids. J Bacteriol (1984) 1.27
N conjugative transfer system of plasmid pCU1. J Bacteriol (1985) 1.22
Conjugation-independent, site-specific recombination at the oriT of the IncW plasmid R388 mediated by TrwC. J Bacteriol (1994) 1.18
Homology among arsenate resistance determinants of R factors in Escherichia coli. Antimicrob Agents Chemother (1984) 1.11
Plasmid pKM101 encodes two nonhomologous antirestriction proteins (ArdA and ArdB) whose expression is controlled by homologous regulatory sequences. J Bacteriol (1993) 1.10
Fitness of Escherichia coli strains carrying expressed and partially silent IncN and IncP1 plasmids. BMC Microbiol (2012) 1.07
Improved purification and characterization of the OXA-2 beta-lactamase. Biochem J (1984) 1.06
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Inverted repeats in the DNA of plasmid pCU1. J Bacteriol (1983) 0.96
IncN plasmid pKM101 and IncI1 plasmid ColIb-P9 encode homologous antirestriction proteins in their leading regions. J Bacteriol (1992) 0.96
Evidence of antibiotic resistance gene silencing in Escherichia coli. Antimicrob Agents Chemother (2006) 0.90
Complete sequence of an IncN plasmid, pIMP-HZ1, carrying blaIMP-4 in a Klebsiella pneumoniae strain associated with medical travel to China. Antimicrob Agents Chemother (2012) 0.86
Transfer of IncN plasmids to Pseudomonas aeruginosa. Antimicrob Agents Chemother (1982) 0.85
Isolation and characterization of kikA, a region on IncN group plasmids that determines killing of Klebsiella oxytoca. J Bacteriol (1992) 0.83
Recent independent emergence of multiple multidrug-resistant Serratia marcescens clones within the United Kingdom and Ireland. Genome Res (2016) 0.82
A plasmid carrying mucA and mucB genes from pKM101 in Haemophilus influenzae and Escherichia coli. J Bacteriol (1989) 0.78
Bacteriophage PSP3 and phi R73 activator proteins: analysis of promoter specificities. J Bacteriol (1996) 0.76
Genetic location of certain mutations conferring recombination deficiency in Escherichia coli. J Bacteriol (1969) 11.34
Genetic analysis of recombination-deficient mutants of Escherichia coli K-12 carrying rec mutations cotransducible with thyA. J Bacteriol (1969) 7.66
Characteristics of some multiply recombination-deficient strains of Escherichia coli. J Bacteriol (1969) 7.04
Randomised controlled trial of nasal ventilation in acute ventilatory failure due to chronic obstructive airways disease. Lancet (1993) 5.43
The calcium current of Helix neuron. J Gen Physiol (1978) 5.18
Spermine and spermidine as gating molecules for inward rectifier K+ channels. Science (1994) 4.82
Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy. Circulation (1995) 4.48
A novel potassium channel with delayed rectifier properties isolated from rat brain by expression cloning. Nature (1989) 3.99
In vivo growth characteristics of leucine and methionine auxotrophic mutants of Mycobacterium bovis BCG generated by transposon mutagenesis. Infect Immun (1995) 3.56
The future of general practice in Newcastle upon Tyne. Lancet (1986) 3.47
Properties of internally perfused, voltage-clamped, isolated nerve cell bodies. J Gen Physiol (1978) 3.44
Receptor-effector coupling by G proteins. Biochim Biophys Acta (1990) 3.31
Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7. Proc Natl Acad Sci U S A (1984) 3.25
Calcium current-dependent and voltage-dependent inactivation of calcium channels in Helix aspersa. J Physiol (1981) 3.23
Exchange of conduction pathways between two related K+ channels. Science (1991) 3.09
Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. J Cell Biol (1993) 2.95
Cardiac Na currents and the inactivating, reopening, and waiting properties of single cardiac Na channels. J Gen Physiol (1985) 2.93
Gating of inwardly rectifying K+ channels localized to a single negatively charged residue. Nature (1994) 2.91
Sodium current in single rat heart muscle cells. J Physiol (1981) 2.83
Transformation by Wnt family proteins correlates with regulation of beta-catenin. Cell Growth Differ (1997) 2.74
The elimination by acridine orange of F30 from recombination-deficient strains of Escherichia coli K12. Genetics (1968) 2.72
A G protein directly regulates mammalian cardiac calcium channels. Science (1987) 2.58
Interprofessional collaboration in primary health care. J R Coll Gen Pract (1987) 2.56
Evidence for high-energy extraterrestrial neutrinos at the IceCube detector. Science (2013) 2.56
Heterologous regulation of the cardiac Ca2+ channel alpha 1 subunit by skeletal muscle beta and gamma subunits. Implications for the structure of cardiac L-type Ca2+ channels. J Biol Chem (1991) 2.55
Note on the nitrogen content of certain proteins. Biochem J (1932) 2.54
Direct activation of mammalian atrial muscarinic potassium channels by GTP regulatory protein Gk. Science (1987) 2.50
Interactions of the 5-hydroxytryptamine 3 antagonist class of antiemetic drugs with human cardiac ion channels. J Pharmacol Exp Ther (2000) 2.47
HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine. Circulation (1996) 2.46
Early outward current in rat single ventricular cells. Circ Res (1984) 2.41
Inactivation determined by a single site in K+ pores. Pflugers Arch (1993) 2.37
A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line. Cell (1986) 2.32
Multiple mechanisms of Na+ channel--linked long-QT syndrome. Circ Res (1996) 2.29
Two classes of Flac mutants insensitive to transfer inhibition by an F-like R factor. Mol Gen Genet (1971) 2.27
Alteration and restoration of K+ channel function by deletions at the N- and C-termini. Neuron (1990) 2.26
The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix. EMBO J (1990) 2.25
The elimination of Flac+ from Escherichia coli by mutagenic agents. Biochem Biophys Res Commun (1967) 2.25
Sodium current in single heart muscle cells. Nature (1979) 2.19
Patch and whole cell calcium currents recorded simultaneously in snail neurons. J Gen Physiol (1984) 2.17
Molecular determinants of dofetilide block of HERG K+ channels. Circ Res (1998) 2.13
Prognosis in the irritable bowel syndrome: a 5-year prospective study. Lancet (1987) 2.13
A comparison of calcium currents in rat and guinea pig single ventricular cells. Circ Res (1984) 2.12
Increased chloride conductance as the proximate cause of hydrogen ion concentration effects in Aplysia neurons. J Gen Physiol (1970) 2.09
GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents. Science (1992) 2.09
Normalization of current kinetics by interaction between the alpha 1 and beta subunits of the skeletal muscle dihydropyridine-sensitive Ca2+ channel. Nature (1991) 2.09
The agonist effect of dihydropyridines on Ca channels. Nature (1984) 2.07
Induction of calcium currents by the expression of the alpha 1-subunit of the dihydropyridine receptor from skeletal muscle. Nature (1989) 2.04
Intracellular protein breakdown in non-growing cells of Escherichia coli. Biochem J (1967) 2.03
Variable participation of 5-HT1-like receptors and 5-HT2 receptors in serotonin-induced contraction of human isolated coronary arteries. 5-HT1-like receptors resemble cloned 5-HT1D beta receptors. Circulation (1994) 2.02
Identity of a novel delayed rectifier current from human heart with a cloned K+ channel current. Circ Res (1993) 2.02
Similarity of unitary Ca2+ currents in three different species. Nature (1982) 2.00
Scanning calorimetric study of the thermal unfolding of catabolite activator protein from Escherichia coli in the absence and presence of cyclic mononucleotides. Biochemistry (1988) 2.00
First observation of PeV-energy neutrinos with IceCube. Phys Rev Lett (2013) 2.00
Location of the origin of transfer of the sex factor F. J Bacteriol (1972) 1.98
Light response of a giant Aplysia neuron. J Gen Physiol (1973) 1.96
Genetic structure, function and regulation of the transposable element IS21. Mol Gen Genet (1989) 1.93
A description of activation and conduction in calcium channels based on tail and turn-on current measurements in the snail. J Physiol (1983) 1.93
K+ pore structure revealed by reporter cysteines at inner and outer surfaces. Neuron (1995) 1.91
Leucine auxotrophy restricts growth of Mycobacterium bovis BCG in macrophages. Infect Immun (1996) 1.89
Wnt-1 regulation of connexin43 in cardiac myocytes. J Clin Invest (2000) 1.87
Specification of pore properties by the carboxyl terminus of inwardly rectifying K+ channels. Science (1994) 1.85
Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene. Mol Cell Biol (1985) 1.85
Relapsing experimental allergic encephalomyelitis in the SJL/J mouse. Lab Invest (1981) 1.84
Unified account of the variable effects of carbon dioxide on nerve cells. Science (1970) 1.84
C-terminus determinants for Mg2+ and polyamine block of the inward rectifier K+ channel IRK1. EMBO J (1995) 1.84
Discovery of very-high-energy gamma-rays from the Galactic Centre ridge. Nature (2006) 1.81
The alpha subunit of the GTP binding protein Gk opens atrial potassium channels. Science (1987) 1.79
Coupling of ATP-sensitive K+ channels to A1 receptors by G proteins in rat ventricular myocytes. Am J Physiol (1990) 1.79
The units of calcium conduction in Helix neurones. Nature (1978) 1.78
DNA sequence of the F traALE region that includes the gene for F pilin. J Bacteriol (1984) 1.78
Interaction between calcium ions and surface charge as it relates to calcium currents. J Membr Biol (1983) 1.76
Nonmodal gating of cardiac calcium channels as revealed by dihydropyridines. J Gen Physiol (1989) 1.76
A 5-hydroxytryptamine receptor in human atrium. Br J Pharmacol (1990) 1.76
SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. Neuropharmacology (1997) 1.76
The insertion sequence IS21 of R68.45 and the molecular basis for mobilization of the bacterial chromosome. Plasmid (1981) 1.75
The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells. Mol Cell Biol (1992) 1.75
Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias. J Cardiovasc Electrophysiol (2000) 1.74
KChAP as a chaperone for specific K(+) channels. Am J Physiol Cell Physiol (2000) 1.73
Fast and slow gating of sodium channels encoded by a single mRNA. Neuron (1990) 1.71
Electrocardiographic prediction of abnormal genotype in congenital long QT syndrome: experience in 101 related family members. J Cardiovasc Electrophysiol (2001) 1.71
Patterns of internal and external tetraethylammonium block in four homologous K+ channels. Mol Pharmacol (1991) 1.71
Pseudoloma neurophilia n. g., n. sp., a new microsporidium from the central nervous system of the zebrafish (Danio rerio). J Eukaryot Microbiol (2002) 1.70
Structure of the human oestrogen-responsive gene pS2. Nucleic Acids Res (1987) 1.70
Two nonredundant SecA homologues function in mycobacteria. J Bacteriol (2001) 1.69
Differences between the deep pores of K+ channels determined by an interacting pair of nonpolar amino acids. Neuron (1992) 1.69
Plasmid specificity of two proteins required for conjugation in E. coli K12. Nat New Biol (1971) 1.68
Characteristics of E. coli K12 strains carrying both an F prime and an R factor. Genet Res (1970) 1.67
ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels. Cell (1990) 1.67
Rapid beta-adrenergic modulation of cardiac calcium channel currents by a fast G protein pathway. Science (1989) 1.66
The suction pipette method for internal perfusion and voltage clamp of small excitable cells. J Neurosci Methods (1980) 1.64
Whole-cell and single-channel calcium currents of isolated smooth muscle cells from saphenous vein. Circ Res (1987) 1.63
Trypsin inhibits the action of tetrodotoxin on neurones. Nature (1977) 1.61
Plasmid co-integrates of prophage lambda and R factor R100. J Bacteriol (1976) 1.61
Cyclooxygenase-2: a target for the prevention and treatment of breast cancer. Endocr Relat Cancer (2001) 1.61
The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway. Mol Cell Biol (1987) 1.60
Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide. Circulation (1996) 1.60
Astrocytic glycogen influences axon function and survival during glucose deprivation in central white matter. J Neurosci (2000) 1.59