Published in Mol Cell Proteomics on April 01, 2002
Comparing protein abundance and mRNA expression levels on a genomic scale. Genome Biol (2003) 6.98
Global signatures of protein and mRNA expression levels. Mol Biosyst (2009) 4.43
Defining the transcriptome and proteome in three functionally different human cell lines. Mol Syst Biol (2010) 3.00
Abandon the mouse research ship? Not just yet! Shock (2014) 2.60
DNA-encoded antibody libraries: a unified platform for multiplexed cell sorting and detection of genes and proteins. J Am Chem Soc (2007) 2.42
Randomized phase III trial of gemcitabine-based chemotherapy with in situ RRM1 and ERCC1 protein levels for response prediction in non-small-cell lung cancer. J Clin Oncol (2009) 2.13
Protein analysis by shotgun/bottom-up proteomics. Chem Rev (2013) 2.13
Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate. BMC Genomics (2008) 1.95
Protein profiles associated with survival in lung adenocarcinoma. Proc Natl Acad Sci U S A (2003) 1.86
Comparing the use of Affymetrix to spotted oligonucleotide microarrays using two retinal pigment epithelium cell lines. Mol Vis (2003) 1.77
Polyamine pathway contributes to the pathogenesis of Parkinson disease. Proc Natl Acad Sci U S A (2010) 1.73
Integrated molecular signature of disease: analysis of influenza virus-infected macaques through functional genomics and proteomics. J Virol (2006) 1.63
Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum. BMC Genomics (2011) 1.60
Hepatitis C virus receptors claudin-1 and occludin after liver transplantation and influence on early viral kinetics. Hepatology (2011) 1.54
Investigating the correspondence between transcriptomic and proteomic expression profiles using coupled cluster models. Bioinformatics (2008) 1.51
Kinomic profiling of electromagnetic navigational bronchoscopy specimens: a new approach for personalized medicine. PLoS One (2014) 1.48
Phosphorylated FADD induces NF-kappaB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas. Proc Natl Acad Sci U S A (2005) 1.44
The role of Dickkopf-3 overexpression in esophageal adenocarcinoma. J Thorac Cardiovasc Surg (2015) 1.43
Expression of platelet-derived growth factor BB, erythropoietin and erythropoietin receptor in canine and feline osteosarcoma. Vet J (2015) 1.39
Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks. BMC Syst Biol (2012) 1.36
The protein expression landscape of the Arabidopsis root. Proc Natl Acad Sci U S A (2012) 1.36
Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes. PLoS Comput Biol (2012) 1.32
Complementary proteome and transcriptome profiling in phosphate-deficient Arabidopsis roots reveals multiple levels of gene regulation. Mol Cell Proteomics (2012) 1.29
From bytes to bedside: data integration and computational biology for translational cancer research. PLoS Comput Biol (2007) 1.27
The identification of potential factors associated with the development of type 2 diabetes: a quantitative proteomics approach. Mol Cell Proteomics (2008) 1.27
Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells. Proteomics (2006) 1.24
Proteomic analysis of mantle-cell lymphoma by protein microarray. Blood (2005) 1.23
Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer. BMC Cancer (2012) 1.17
Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis. Br J Cancer (2008) 1.16
Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers. PLoS One (2009) 1.16
Thymidylate synthase in situ protein expression and survival in stage I nonsmall-cell lung cancer. Cancer (2008) 1.15
Regulation of mRNA translation in renal physiology and disease. Am J Physiol Renal Physiol (2009) 1.13
Integrating proteomic and transcriptomic high-throughput surveys for search of new biomarkers of colon tumors. Funct Integr Genomics (2010) 1.12
Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced interleukin-6 secretion. Genes Immun (2010) 1.11
Integrated analysis of transcriptomic and proteomic data. Curr Genomics (2013) 1.09
The evolving role of mass spectrometry in cancer biomarker discovery. Cancer Biol Ther (2009) 1.09
Protein profiling of plasma membranes defines aberrant signaling pathways in mantle cell lymphoma. Mol Cell Proteomics (2009) 1.07
Systems analysis of seed filling in Arabidopsis: using general linear modeling to assess concordance of transcript and protein expression. Plant Physiol (2010) 1.07
Comparison of mRNA and protein measures of cytokines following vaccination with human papillomavirus-16 L1 virus-like particles. Cancer Epidemiol Biomarkers Prev (2010) 1.06
Bone morphogenetic protein 7 is expressed in prostate cancer metastases and its effects on prostate tumor cells depend on cell phenotype and the tumor microenvironment. Neoplasia (2010) 1.06
Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma. PLoS One (2012) 1.05
Nasal embryonic LHRH factor (NELF) mutations in patients with normosmic hypogonadotropic hypogonadism and Kallmann syndrome. Fertil Steril (2011) 1.05
From big data analysis to personalized medicine for all: challenges and opportunities. BMC Med Genomics (2015) 1.04
Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis. Am J Pathol (2004) 1.04
Functional VEGF and VEGF receptors are expressed in human medulloblastomas. Neuro Oncol (2007) 1.04
Exon level integration of proteomics and microarray data. BMC Bioinformatics (2008) 1.03
Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system. Sci Rep (2015) 1.02
Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice. Toxicol Appl Pharmacol (2006) 1.00
Bioinformatic identification of proteins with tissue-specific expression for biomarker discovery. BMC Med (2012) 1.00
Determination of strongly overlapping signaling activity from microarray data. BMC Bioinformatics (2006) 0.99
A systems biology approach reveals common metastatic pathways in osteosarcoma. BMC Syst Biol (2012) 0.99
Voltage-gated K+ channels in adipogenic differentiation of bone marrow-derived human mesenchymal stem cells. Acta Pharmacol Sin (2012) 0.98
Combined analysis of transcriptome and proteome data as a tool for the identification of candidate biomarkers in renal cell carcinoma. Proteomics (2009) 0.98
Translating mRNAs strongly correlate to proteins in a multivariate manner and their translation ratios are phenotype specific. Nucleic Acids Res (2013) 0.97
Genome-wide transcriptome and proteome analysis on different developmental stages of Cordyceps militaris. PLoS One (2012) 0.97
L-type amino acid transporter-1 overexpression and melphalan sensitivity in Barrett's adenocarcinoma. Neoplasia (2004) 0.97
Data-independent proteomic screen identifies novel tamoxifen agonist that mediates drug resistance. J Proteome Res (2011) 0.97
Transcriptional and translational regulatory responses to iron limitation in the globally distributed marine bacterium Candidatus pelagibacter ubique. PLoS One (2010) 0.96
Reconstructing regulatory network transitions. Trends Cell Biol (2011) 0.96
Blunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV-exposed, seronegative female sex workers in Kenya. PLoS One (2012) 0.96
Label-free quantitative LC-MS proteomics of Alzheimer's disease and normally aged human brains. J Proteome Res (2012) 0.96
Identification of ENO1 as a potential sputum biomarker for early-stage lung cancer by shotgun proteomics. Clin Lung Cancer (2014) 0.95
Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration. Hum Mol Genet (2015) 0.95
Testicular postgenomics: targeting the regulation of spermatogenesis. Philos Trans R Soc Lond B Biol Sci (2010) 0.94
An integrative genomic and proteomic approach to chemosensitivity prediction. Int J Oncol (2009) 0.94
The +4G site in Kozak consensus is not related to the efficiency of translation initiation. PLoS One (2007) 0.93
Protein expression in a Drosophila model of Parkinson's disease. J Proteome Res (2007) 0.93
Toward a genome-wide landscape of translational control. Cold Spring Harb Perspect Biol (2013) 0.92
The predictive power of brain mRNA mappings for in vivo protein density: a positron emission tomography correlation study. J Cereb Blood Flow Metab (2014) 0.92
A comprehensive in silico expression analysis of RNA binding proteins in normal and tumor tissue: Identification of potential players in tumor formation. RNA Biol (2009) 0.91
Proteomic assessment of the acute phase of dystrophin deficiency in mdx mice. Eur J Appl Physiol (2011) 0.91
Surviving hypoxia by modulation of mRNA translation rate. J Cell Mol Med (2009) 0.91
Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. Psychopharmacology (Berl) (2011) 0.90
PARE: a tool for comparing protein abundance and mRNA expression data. BMC Bioinformatics (2007) 0.90
Largazole, a class I histone deacetylase inhibitor, enhances TNF-α-induced ICAM-1 and VCAM-1 expression in rheumatoid arthritis synovial fibroblasts. Toxicol Appl Pharmacol (2013) 0.90
Identifier mapping performance for integrating transcriptomics and proteomics experimental results. BMC Bioinformatics (2011) 0.90
HAGE, a cancer/testis antigen expressed at the protein level in a variety of cancers. Cancer Immun (2010) 0.90
Genomics and proteomics in liver fibrosis and cirrhosis. Fibrogenesis Tissue Repair (2012) 0.90
Prenatal ethanol exposure alters adult hippocampal VGLUT2 expression with concomitant changes in promoter DNA methylation, H3K4 trimethylation and miR-467b-5p levels. Epigenetics Chromatin (2015) 0.89
Semi-quantitative analysis of changes in the plasma peptidome of Manduca sexta larvae and their correlation with the transcriptome variations upon immune challenge. Insect Biochem Mol Biol (2014) 0.89
An Akt-dependent increase in canonical Wnt signaling and a decrease in sclerostin protein levels are involved in strontium ranelate-induced osteogenic effects in human osteoblasts. J Biol Chem (2011) 0.89
Differential effect of postnatal lead exposure on gene expression in the hippocampus and frontal cortex. J Mol Neurosci (2011) 0.88
Expression of the stress response oncoprotein LEDGF/p75 in human cancer: a study of 21 tumor types. PLoS One (2012) 0.88
Hypoxic transcription gene profiles under the modulation of nitric oxide in nuclear run on-microarray and proteomics. BMC Genomics (2009) 0.88
KIAA0101 (OEACT-1), an expressionally down-regulated and growth-inhibitory gene in human hepatocellular carcinoma. BMC Cancer (2006) 0.88
Expression of annexin-A1 and galectin-1 anti-inflammatory proteins and mRNA in chronic gastritis and gastric cancer. Mediators Inflamm (2013) 0.88
Resveratrol metabolites modify adipokine expression and secretion in 3T3-L1 pre-adipocytes and mature adipocytes. PLoS One (2013) 0.87
Impact of butyrate on PKM2 and HSP90β expression in human colon tissues of different transformation stages: a comparison of gene and protein data. Genes Nutr (2011) 0.87
ADAM metallopeptidase domain 17 (ADAM17) is naturally processed through major histocompatibility complex (MHC) class I molecules and is a potential immunotherapeutic target in breast, ovarian and prostate cancers. Clin Exp Immunol (2010) 0.87
Developmental timing of the effects of maternal care on gene expression and epigenetic regulation of hormone receptor levels in female rats. Endocrinology (2013) 0.87
A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability. J Transl Med (2014) 0.87
Network analysis of epidermal growth factor signaling using integrated genomic, proteomic and phosphorylation data. PLoS One (2012) 0.87
Global protein-expression analysis of bone and soft tissue sarcomas. Clin Orthop Relat Res (2008) 0.86
Signal stability of Cy3 and Cy5 on antibody microarrays. Proteome Sci (2006) 0.86
Prediction of individual response to anticancer therapy: historical and future perspectives. Cell Mol Life Sci (2014) 0.86
Mass spectrometry based method to increase throughput for kinome analyses using ATP probes. Anal Chem (2013) 0.86
Responses of the Emiliania huxleyi proteome to ocean acidification. PLoS One (2013) 0.85
Systematic investigation of global coordination among mRNA and protein in cellular society. BMC Genomics (2010) 0.85
Cancer testis antigen OY-TES-1 expression and serum immunogenicity in colorectal cancer: its relationship to clinicopathological parameters. Int J Clin Exp Pathol (2013) 0.85
Cytological and comparative proteomic analyses on male sterility in Brassica napus L. induced by the chemical hybridization agent monosulphuron ester sodium. PLoS One (2013) 0.85
The landscape of somatic copy-number alteration across human cancers. Nature (2010) 31.88
Somatic mutations affect key pathways in lung adenocarcinoma. Nature (2008) 30.02
International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol (2011) 21.49
Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med (2002) 21.28
Characterizing the cancer genome in lung adenocarcinoma. Nature (2007) 16.48
Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med (2008) 10.12
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis. BMC Bioinformatics (2010) 7.78
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet (2009) 7.48
p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol (2007) 6.87
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure. N Engl J Med (2002) 5.50
EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer. J Clin Oncol (2008) 5.46
EML4-ALK fusion lung cancer: a rare acquired event. Neoplasia (2008) 5.22
Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma. Nat Med (2010) 4.81
Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. Cancer Discov (2011) 4.80
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet (2004) 4.51
Evaluation of patients with pulmonary nodules: when is it lung cancer?: ACCP evidence-based clinical practice guidelines (2nd edition). Chest (2007) 4.49
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity. Nat Genet (2013) 4.48
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. Cancer Res (2003) 4.30
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
Gene expression signatures for predicting prognosis of squamous cell and adenocarcinomas of the lung. Cancer Res (2006) 4.11
A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure. Nat Med (2008) 3.98
Lung cancer signatures in plasma based on proteome profiling of mouse tumor models. Cancer Cell (2011) 3.88
A biomarker panel for acute graft-versus-host disease. Blood (2008) 3.83
Interlaboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays. Clin Cancer Res (2005) 3.79
Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas. Cancer Res (2002) 3.62
Chemoselection as a strategy for organ preservation in advanced oropharynx cancer: response and survival positively associated with HPV16 copy number. J Clin Oncol (2008) 3.55
Exploring the public understanding of basic genetic concepts. J Genet Couns (2004) 3.53
Meta-analysis for surrogacy: accelerated failure time models and semicompeting risks modeling. Biometrics (2011) 3.38
Subgroup identification from randomized clinical trial data. Stat Med (2011) 3.22
Criteria for the use of omics-based predictors in clinical trials. Nature (2013) 3.15
MicroRNA classifiers for predicting prognosis of squamous cell lung cancer. Cancer Res (2009) 3.05
Gastric cancer, version 2.2013: featured updates to the NCCN Guidelines. J Natl Compr Canc Netw (2013) 3.03
Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways. Cancer Cell (2007) 3.02
Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function. J Biol Chem (2002) 3.02
A compendium of potential biomarkers of pancreatic cancer. PLoS Med (2009) 3.00
Interleukin-6 predicts recurrence and survival among head and neck cancer patients. Cancer (2008) 2.98
The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. Genet Med (2009) 2.91
Verification and unmasking of widely used human esophageal adenocarcinoma cell lines. J Natl Cancer Inst (2010) 2.79
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer. Nat Med (2011) 2.77
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study. Nat Biotechnol (2006) 2.66
Podocyte hypertrophy, "adaptation," and "decompensation" associated with glomerular enlargement and glomerulosclerosis in the aging rat: prevention by calorie restriction. J Am Soc Nephrol (2005) 2.49
Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling. Cancer Cell (2005) 2.47
Amplification of chromosomal segment 4q12 in non-small cell lung cancer. Cancer Biol Ther (2009) 2.47
Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism. Mol Cell Biol (2002) 2.44
Mitotic rate and younger age are predictors of sentinel lymph node positivity: lessons learned from the generation of a probabilistic model. Ann Surg Oncol (2004) 2.42
Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction. Am J Pathol (2003) 2.38
Development and validation of a dynamic prognostic tool for prostate cancer recurrence using repeated measures of posttreatment PSA: a joint modeling approach. Biostatistics (2009) 2.38
Multiple genes for essential-hypertension susceptibility on chromosome 1q. Am J Hum Genet (2006) 2.34
Genetic variation in 8q24 associated with risk of colorectal cancer. Cancer Biol Ther (2007) 2.32
A mouse to human search for plasma proteome changes associated with pancreatic tumor development. PLoS Med (2008) 2.31
Targeted imaging of esophageal neoplasia with a fluorescently labeled peptide: first-in-human results. Sci Transl Med (2013) 2.30
Sugar-sweetened beverage, sugar intake of individuals, and their blood pressure: international study of macro/micronutrients and blood pressure. Hypertension (2011) 2.29
Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res (2012) 2.26
Malignant pheochromocytoma: current status and initiatives for future progress. Endocr Relat Cancer (2004) 2.20
A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions. RNA (2008) 2.16
Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas. Am J Surg Pathol (2006) 2.15
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
The solitary pulmonary nodule. Chest (2003) 2.09
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Diabetes (2011) 2.09
SNP set association analysis for familial data. Genet Epidemiol (2012) 2.08
Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk. Oncogene (2005) 2.07
Semiparametric modeling of longitudinal measurements and time-to-event data--a two-stage regression calibration approach. Biometrics (2008) 2.05
Genes, environment, and cardiovascular disease. Arterioscler Thromb Vasc Biol (2003) 2.04
Esophageal and esophagogastric junction cancers. J Natl Compr Canc Netw (2011) 2.03
Prognostic immune markers in non-small cell lung cancer. Clin Cancer Res (2011) 2.03
B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression. Proc Natl Acad Sci U S A (2010) 2.03
KRAS-G12C mutation is associated with poor outcome in surgically resected lung adenocarcinoma. J Thorac Oncol (2014) 1.99
Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis. Oncogene (2005) 1.99