PubRank

Ian Sabroe

Author PubWeight™ 55.02‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation. J Leukoc Biol 2011 1.98
2 Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease. J Endotoxin Res 2006 1.86
3 Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish. Blood 2013 1.48
4 Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice. J Clin Invest 2011 1.44
5 The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy. Am J Respir Med 2002 1.38
6 Eotaxin (CCL11) and eotaxin-2 (CCL24) induce recruitment of eosinophils, basophils, neutrophils, and macrophages as well as features of early- and late-phase allergic reactions following cutaneous injection in human atopic and nonatopic volunteers. J Immunol 2002 1.35
7 Cooperative molecular and cellular networks regulate Toll-like receptor-dependent inflammatory responses. FASEB J 2006 1.30
8 The expression and roles of Toll-like receptors in the biology of the human neutrophil. J Leukoc Biol 2005 1.26
9 Agonists of toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor. Thromb Haemost 2005 1.23
10 Pulmonary hypertension in COPD: results from the ASPIRE registry. Eur Respir J 2012 1.16
11 Agonists of toll-like receptors 2 and 4 activate airway smooth muscle via mononuclear leukocytes. Am J Respir Crit Care Med 2005 1.16
12 The role of TLRs in neutrophil activation. Curr Opin Pharmacol 2011 1.15
13 Toll-like receptor (TLR)2 and TLR4 agonists regulate CCR expression in human monocytic cells. J Immunol 2004 1.12
14 Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor. J Immunol 2007 1.12
15 Interleukin-1β regulates CXCL8 release and influences disease outcome in response to Streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages. Infect Immun 2011 1.11
16 Effective caspase inhibition blocks neutrophil apoptosis and reveals Mcl-1 as both a regulator and a target of neutrophil caspase activation. PLoS One 2011 1.08
17 "Dirty little secrets"--endotoxin contamination of recombinant proteins. Immunol Lett 2006 1.06
18 Temporal interleukin-1beta secretion from primary human peripheral blood monocytes by P2X7-independent and P2X7-dependent mechanisms. J Biol Chem 2010 1.05
19 Contrary prostaglandins: the opposing roles of PGD2 and its metabolites in leukocyte function. J Leukoc Biol 2006 1.04
20 Granulocyte apoptosis in the pathogenesis and resolution of lung disease. Clin Sci (Lond) 2006 1.03
21 Impairment of apoptotic cell engulfment by pyocyanin, a toxic metabolite of Pseudomonas aeruginosa. Am J Respir Crit Care Med 2007 1.03
22 Subversion of a lysosomal pathway regulating neutrophil apoptosis by a major bacterial toxin, pyocyanin. J Immunol 2008 1.01
23 A Bayesian approach to copy-number-polymorphism analysis in nuclear pedigrees. Am J Hum Genet 2007 1.01
24 Delta 12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis. J Immunol 2003 1.01
25 The role of interleukin-1beta in direct and toll-like receptor 4-mediated neutrophil activation and survival. Am J Pathol 2004 0.99
26 CCR4 in human allergen-induced late responses in the skin and lung. Eur J Immunol 2002 0.99
27 CCR4 blockade does not inhibit allergic airways inflammation. J Leukoc Biol 2003 0.97
28 Role of interleukin-1 and MyD88-dependent signaling in rhinovirus infection. J Virol 2011 0.97
29 Management dilemmas in acute pulmonary embolism. Thorax 2013 0.93
30 Pulmonary hypertension: diagnosis and management. BMJ 2013 0.93
31 Toll-like receptors and chronic lung disease. Clin Sci (Lond) 2005 0.93
32 Endotoxin tolerance induces selective alterations in neutrophil function. J Leukoc Biol 2005 0.92
33 Roles of neutrophils in the regulation of the extent of human inflammation through delivery of IL-1 and clearance of chemokines. J Leukoc Biol 2012 0.91
34 Variations in eosinophil chemokine responses: an investigation of CCR1 and CCR3 function, expression in atopy, and identification of a functional CCR1 promoter. J Immunol 2003 0.90
35 Staphylococcus aureus induces eosinophil cell death mediated by α-hemolysin. PLoS One 2012 0.90
36 A central role for monocytes in Toll-like receptor-mediated activation of the vasculature. Immunology 2009 0.89
37 A phosphatidylserine species inhibits a range of TLR- but not IL-1beta-induced inflammatory responses by disruption of membrane microdomains. J Immunol 2008 0.88
38 Reducing the toll of inflammatory lung disease. Chest 2007 0.88
39 The generation of highly purified primary human neutrophils and assessment of apoptosis in response to Toll-like receptor ligands. Methods Mol Biol 2009 0.88
40 Indomethacin causes prostaglandin D(2)-like and eotaxin-like selective responses in eosinophils and basophils. J Biol Chem 2002 0.88
41 Pellino-1 selectively regulates epithelial cell responses to rhinovirus. J Virol 2012 0.87
42 Basic science of the innate immune system and the lung. Paediatr Respir Rev 2008 0.85
43 Incapacitating the immune system in cystic fibrosis. Nat Med 2007 0.85
44 Differential and cell-type specific regulation of responses to Toll-like receptor agonists by ISO-1. Immunology 2008 0.83
45 CXCR1+CD4+ T cells in human allergic disease. J Immunol 2004 0.83
46 The role of interleukin-1 and interleukin-18 in pro-inflammatory and anti-viral responses to rhinovirus in primary bronchial epithelial cells. PLoS One 2013 0.83
47 9alpha,11beta-PGF2 and its stereoisomer PGF2alpha are novel agonists of the chemoattractant receptor, CRTH2. FEBS Lett 2005 0.83
48 Ex vivo-expanded bone marrow CD34+ derived neutrophils have limited bactericidal ability. Stem Cells 2008 0.82
49 The identification, characterization, and distribution of guinea pig CCR4 and epitope mapping of a blocking antibody. J Biol Chem 2001 0.82
50 Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists. Am J Respir Crit Care Med 2002 0.80
51 Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis. Thorax 2012 0.80
52 Pathways regulating lipopolysaccharide-induced neutrophil survival revealed by lentiviral transduction of primary human neutrophils. Immunology 2008 0.79
53 Potentiation of TLR4 signalling by plasmin activity. Biochem Biophys Res Commun 2006 0.79
54 Diesel exhaust particle exposure in vitro alters monocyte differentiation and function. PLoS One 2012 0.78
55 Characterisation of the biological activity of recombinant equine eotaxin in vitro. Cytokine 2002 0.75
56 Practical phenotyping of difficult asthma. Thorax 2013 0.75