Published in Exp Cell Res on August 01, 2002
Organizing the cell cortex: the role of ERM proteins. Nat Rev Mol Cell Biol (2010) 5.05
Synaptotagmin-mediated vesicle fusion regulates cell migration. Nat Immunol (2010) 2.09
Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes. Immunology (2004) 1.82
Bringing up the rear: defining the roles of the uropod. Nat Rev Mol Cell Biol (2009) 1.74
Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway. J Cell Biol (2008) 1.35
Type Igamma PIP kinase is a novel uropod component that regulates rear retraction during neutrophil chemotaxis. Mol Biol Cell (2007) 1.27
Rho GEF Lsc is required for normal polarization, migration, and adhesion of formyl-peptide-stimulated neutrophils. Blood (2005) 1.16
Flotillins interact with PSGL-1 in neutrophils and, upon stimulation, rapidly organize into membrane domains subsequently accumulating in the uropod. PLoS One (2009) 1.13
Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement. J Cell Biol (2007) 1.12
Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motility. Proc Natl Acad Sci U S A (2010) 1.05
Hax1 regulates neutrophil adhesion and motility through RhoA. J Cell Biol (2011) 1.02
Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice. Blood (2011) 1.00
Regulation of focal adhesion kinase activation, breast cancer cell motility, and amoeboid invasion by the RhoA guanine nucleotide exchange factor Net1. Mol Cell Biol (2013) 0.97
Conformational switching in ezrin regulates morphological and cytoskeletal changes required for B cell chemotaxis. J Immunol (2011) 0.92
Characterization of the Ca2+ -regulated ezrin-S100P interaction and its role in tumor cell migration. J Biol Chem (2008) 0.92
Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes. BMC Cell Biol (2011) 0.91
Polarization and migration of hematopoietic stem and progenitor cells rely on the RhoA/ROCK I pathway and an active reorganization of the microtubule network. J Biol Chem (2010) 0.90
Comparative study of ezrin phosphorylation among different tissues: more is good; too much is bad. Am J Physiol Cell Physiol (2008) 0.87
Lsc activity is controlled by oligomerization and regulates integrin adhesion. Mol Immunol (2007) 0.84
A role for Rab27 in neutrophil chemotaxis and lung recruitment. BMC Cell Biol (2014) 0.79
Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient. J Exp Med (2015) 0.78
The ezrin-radixin-moesin family of proteins in the regulation of B-cell immune response. Crit Rev Immunol (2015) 0.76
Leading from the Back: The Role of the Uropod in Neutrophil Polarization and Migration. Dev Cell (2016) 0.75
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet (2008) 8.63
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nat Genet (2003) 7.04
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet (2005) 5.35
A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. Nat Genet (2009) 5.29
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nat Genet (2003) 4.61
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells. Int Immunol (2004) 4.59
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population. Diabetes (2007) 3.24
Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma. Nat Genet (2011) 3.19
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet (2005) 3.15
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies. Am J Hum Genet (2008) 3.12
Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. Gastroenterology (2009) 3.04
Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis. Int Immunol (2006) 2.93
Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. Nat Genet (2010) 2.92
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. Nat Genet (2010) 2.81
alpha-Klotho as a regulator of calcium homeostasis. Science (2007) 2.71
The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity. J Biol Chem (2003) 2.59
Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction. J Hum Genet (2006) 2.41
A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. Nat Genet (2010) 2.34
Thermally activated delayed fluorescence from Sn(4+)-porphyrin complexes and their application to organic light emitting diodes--a novel mechanism for electroluminescence. Adv Mater (2009) 2.32
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. Nat Genet (2012) 2.31
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. Nat Genet (2011) 2.27
A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Nat Genet (2009) 2.26
Ubiquitination of APOBEC3G by an HIV-1 Vif-Cullin5-Elongin B-Elongin C complex is essential for Vif function. J Biol Chem (2005) 2.21
PD-1-PD-1 ligand interaction contributes to immunosuppressive microenvironment of Hodgkin lymphoma. Blood (2008) 2.15
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. Nat Genet (2011) 2.10
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet (2012) 2.05
Autophagy protects the proximal tubule from degeneration and acute ischemic injury. J Am Soc Nephrol (2011) 2.04
Prognosis of Japanese metastatic renal cell carcinoma patients in the cytokine era: a cooperative group report of 1463 patients. Eur Urol (2009) 2.03
Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation. J Biol Chem (2004) 2.01
Late-phase thromboembolism after catheter ablation for paroxysmal atrial fibrillation. Circ J (2014) 1.98
Impact of statin use before the onset of acute myocardial infarction on coronary plaque morphology of the culprit lesion. Angiology (2012) 1.97
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. Hum Mol Genet (2011) 1.96
A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility. Hum Mol Genet (2008) 1.91
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations. Nat Genet (2012) 1.90
Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations. Nat Genet (2010) 1.90
Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis. Nat Genet (2013) 1.90
Ethyl pyruvate ameliorates distant organ injury in a murine model of acute necrotizing pancreatitis. Crit Care Med (2004) 1.88
Clinical implications of reconnection between the left atrium and isolated pulmonary veins provoked by adenosine triphosphate after extensive encircling pulmonary vein isolation. J Cardiovasc Electrophysiol (2007) 1.88
Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial. Cancer Prev Res (Phila) (2010) 1.86
A genome-wide association study identifies common variants near LBX1 associated with adolescent idiopathic scoliosis. Nat Genet (2011) 1.86
Chloroquine in cancer therapy: a double-edged sword of autophagy. Cancer Res (2013) 1.86
p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma. J Allergy Clin Immunol (2002) 1.84
Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population. Hum Mol Genet (2010) 1.83
HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease. Gastroenterology (2011) 1.83
APOBEC3G targets specific virus species. J Virol (2004) 1.78
A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E. Hum Genet (2010) 1.75
Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). PLoS Genet (2011) 1.75
A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population. Nat Genet (2006) 1.73
Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population. Nat Genet (2008) 1.73
Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock. Am J Physiol Gastrointest Liver Physiol (2002) 1.70
IL-6 is essential for development of gut barrier dysfunction after hemorrhagic shock and resuscitation in mice. Am J Physiol Gastrointest Liver Physiol (2003) 1.70
Impact of adenosine-provoked acute dormant pulmonary vein conduction on recurrence of atrial fibrillation. J Cardiovasc Electrophysiol (2011) 1.70
Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase. Mol Carcinog (2010) 1.69
Multiple loci are associated with white blood cell phenotypes. PLoS Genet (2011) 1.65
Natural alpha interferon-producing cells respond to human immunodeficiency virus type 1 with alpha interferon production and maturation into dendritic cells. J Virol (2003) 1.64
Safe and effective ablation of atrial fibrillation: importance of esophageal temperature monitoring to avoid periesophageal nerve injury as a complication of pulmonary vein isolation. J Cardiovasc Electrophysiol (2008) 1.64
Qualitative and quantitative ultrashort echo time (UTE) imaging of cortical bone. J Magn Reson (2010) 1.64
Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese. Nat Genet (2012) 1.59
A genome-wide association study identifies three new risk loci for Kawasaki disease. Nat Genet (2012) 1.58
Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. Nat Genet (2012) 1.58
A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese. Nat Genet (2010) 1.57
Reentrant tachycardia in pulmonary veins of patients with paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol (2003) 1.57
Long-term clinical outcome of extensive pulmonary vein isolation-based catheter ablation therapy in patients with paroxysmal and persistent atrial fibrillation. Heart (2010) 1.55
Bundle branch reentrant ventricular tachycardia with wide and narrow QRS morphology. Circ Arrhythm Electrophysiol (2013) 1.54
Incremental value of combining 64-slice computed tomography angiography with stress nuclear myocardial perfusion imaging to improve noninvasive detection of coronary artery disease. J Nucl Cardiol (2009) 1.54
High-level expression of BCL3 differentiates t(2;5)(p23;q35)-positive anaplastic large cell lymphoma from Hodgkin disease. Blood (2002) 1.54
Murine retrovirus escapes from murine APOBEC3 via two distinct novel mechanisms. Curr Biol (2006) 1.53
Renal function after catheter ablation of atrial fibrillation. Circulation (2011) 1.53
A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population. Nat Genet (2012) 1.51
APOBEC3G targets human T-cell leukemia virus type 1. Retrovirology (2005) 1.51
Profound cardiac sympathetic denervation occurs in Parkinson disease. Brain Pathol (2005) 1.51
Clinical characteristics and management of periesophageal vagal nerve injury complicating left atrial ablation of atrial fibrillation: lessons from eleven cases. J Cardiovasc Electrophysiol (2013) 1.50
Genome-wide association study of pancreatic cancer in Japanese population. PLoS One (2010) 1.50
Prevention of periprocedural ischemic stroke and management of hemorrhagic complications in atrial fibrillation ablation under continuous warfarin administration. J Cardiovasc Electrophysiol (2013) 1.50
A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci. Hum Mol Genet (2010) 1.49
Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes. Am J Hum Genet (2004) 1.49
Incidence of late thromboembolic events after catheter ablation of atrial fibrillation. Circ J (2011) 1.48
Impact of ABO mismatching on the outcomes of allogeneic related and unrelated blood and marrow stem cell transplantations for hematologic malignancies: IPD-based meta-analysis of cohort studies. Transfusion (2009) 1.47
Carbon monoxide inhalation protects rat intestinal grafts from ischemia/reperfusion injury. Am J Pathol (2003) 1.47
Identification of nine novel loci associated with white blood cell subtypes in a Japanese population. PLoS Genet (2011) 1.45
Degeneration of cardiac sympathetic nerve begins in the early disease process of Parkinson's disease. Brain Pathol (2007) 1.44
A case-control study of diet and prostate cancer in Japan: possible protective effect of traditional Japanese diet. Cancer Sci (2004) 1.44
Ultrashort echo time spectroscopic imaging (UTESI) of cortical bone. Magn Reson Med (2007) 1.43
Focal adhesion kinase is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA. Mol Cell Biol (2006) 1.43
Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population. Nat Genet (2011) 1.43
Clinical characteristics of massive air embolism complicating left atrial ablation of atrial fibrillation: lessons from five cases. Europace (2011) 1.43
Catheter ablation of atrial fibrillation in patients with valvular heart disease: long-term follow-up results. J Cardiovasc Electrophysiol (2010) 1.42
Impact of atrial fibrillation termination site and termination mode in catheter ablation on arrhythmia recurrence. Circ J (2013) 1.42
Transplantation of allogeneic hematopoietic stem cells for adult T-cell leukemia: a nationwide retrospective study. Blood (2010) 1.42
A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population. Nat Genet (2010) 1.42
Utility of distinctive local electrogram pattern and aortographic anatomical position in catheter manipulation at coronary cusps. J Cardiovasc Electrophysiol (2010) 1.41
Electrocardiographic characteristics of the variants of idiopathic left ventricular outflow tract ventricular tachyarrhythmias. J Cardiovasc Electrophysiol (2008) 1.41
Retrospective nationwide survey of Japanese patients with transfusion-dependent MDS and aplastic anemia highlights the negative impact of iron overload on morbidity/mortality. Eur J Haematol (2007) 1.41
Clinical utility of adenosine-infusion test at a repeat atrial fibrillation ablation procedure. Heart Rhythm (2012) 1.40
Exaggerated compensatory response to acute respiratory alkalosis in panic disorder is induced by increased lactic acid production. Nephrol Dial Transplant (2008) 1.40