Published in Int J Biochem Cell Biol on October 01, 2002
Hyaluronan as an immune regulator in human diseases. Physiol Rev (2011) 2.74
Role of hyaluronan and hyaluronan-binding proteins in human asthma. J Allergy Clin Immunol (2011) 1.19
Airway remodelling in asthma: from benchside to clinical practice. Can Respir J (2010) 1.11
Regional fibroblast heterogeneity in the lung: implications for remodeling. Am J Respir Crit Care Med (2006) 1.10
Deficiency of endothelial heparan sulfates attenuates allergic airway inflammation. J Immunol (2009) 1.00
Epithelial expression and release of FGF-2 from heparan sulphate binding sites in bronchial tissue in asthma. Thorax (2004) 0.98
Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. Respir Res (2011) 0.89
Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling. Respir Res (2005) 0.87
Fibulin-1 is increased in asthma--a novel mediator of airway remodeling? PLoS One (2010) 0.87
Versican in inflammation and tissue remodeling: the impact on lung disorders. Glycobiology (2014) 0.85
Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology. Biochim Biophys Acta (2014) 0.84
Hyaluronan and Its Heavy Chain Modification in Asthma Severity and Experimental Asthma Exacerbation. J Biol Chem (2015) 0.84
Subepithelial Accumulation of Versican in a Cockroach Antigen-Induced Murine Model of Allergic Asthma. J Histochem Cytochem (2016) 0.78
Differences in MAP kinase phosphorylation in response to mechanical strain in asthmatic fibroblasts. Respir Res (2006) 0.76
Endothelial and leukocyte heparan sulfates regulate the development of allergen-induced airway remodeling in a mouse model. Glycobiology (2014) 0.76
Reconstruction is not renovation - the role of remodeling in asthma. J Asthma Allergy (2009) 0.75
Versican deficiency significantly reduces lung inflammatory response induced by polyinosine-polycytidylic acid stimulation. J Biol Chem (2016) 0.75
Versican accumulates in vascular lesions in pulmonary arterial hypertension. Pulm Circ (2016) 0.75
Interplay of extracellular matrix and leukocytes in lung inflammation. Cell Immunol (2016) 0.75
Hydroxyproline levels in nasal polyps. Eur Arch Otorhinolaryngol (2011) 0.75
Cell Penetrating Peptide Derived from Human Eosinophil Cationic Protein Decreases Airway Allergic Inflammation. Sci Rep (2017) 0.75
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med (2009) 9.38
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J (2013) 8.39
Adult Asthma Consensus Guidelines update 2003. Can Respir J (2004) 3.61
Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest (2006) 3.59
Overdiagnosis of asthma in obese and nonobese adults. CMAJ (2008) 3.23
Global asthma prevalence in adults: findings from the cross-sectional world health survey. BMC Public Health (2012) 3.01
Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression. J Allergy Clin Immunol (2003) 2.98
Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. Am J Respir Crit Care Med (2011) 2.80
Effects of an anti-TSLP antibody on allergen-induced asthmatic responses. N Engl J Med (2014) 2.53
Canadian Thoracic Society Asthma Management Continuum--2010 Consensus Summary for children six years of age and over, and adults. Can Respir J (2010) 2.42
Effects of interleukin-13 blockade on allergen-induced airway responses in mild atopic asthma. Am J Respir Crit Care Med (2010) 2.31
Should combination therapy with inhaled corticosteroids and long-acting beta2-agonists be prescribed as initial maintenance treatment for asthma? CMAJ (2002) 2.30
The effect of obesity on chronic respiratory diseases: pathophysiology and therapeutic strategies. CMAJ (2006) 2.20
Increased IL-33 expression by epithelial cells in bronchial asthma. J Allergy Clin Immunol (2010) 2.17
Summary of recommendations from the Canadian Asthma Consensus guidelines, 2003. CMAJ (2005) 2.12
Canadian Thoracic Society 2012 guideline update: diagnosis and management of asthma in preschoolers, children and adults. Can Respir J (2012) 1.96
Severe asthma in adults: what are the important questions? J Allergy Clin Immunol (2007) 1.85
Diisocyanate antigen-stimulated monocyte chemoattractant protein-1 synthesis has greater test efficiency than specific antibodies for identification of diisocyanate asthma. Am J Respir Crit Care Med (2002) 1.73
Safety and effectiveness of long-acting inhaled beta-agonist bronchodilators when taken with inhaled corticosteroids. Ann Intern Med (2006) 1.71
Proteins with whey-acidic-protein motifs and cancer. Lancet Oncol (2006) 1.67
Obesity and asthma: a specific phenotype? Chest (2008) 1.47
Asthma in pregnancy. BMJ (2007) 1.47
Innate immune responses of airway epithelium to house dust mite are mediated through beta-glucan-dependent pathways. J Allergy Clin Immunol (2009) 1.44
Increased expression of ADAM33 and ADAM8 with disease progression in asthma. J Allergy Clin Immunol (2007) 1.40
Allergen-derived T cell peptides and late asthmatic responses. Am J Respir Crit Care Med (2004) 1.40
Structural changes in airway diseases: characteristics, mechanisms, consequences, and pharmacologic modulation. Chest (2006) 1.38
Budesonide/formoterol for maintenance and relief in uncontrolled asthma vs. high-dose salmeterol/fluticasone. Respir Med (2007) 1.35
Asthma control in Canada: no improvement since we last looked in 1999. Can Fam Physician (2007) 1.24
Prolonged bronchoprotection against inhaled methacholine by inhaled BI 1744, a long-acting beta(2)-agonist, in patients with mild asthma. J Allergy Clin Immunol (2009) 1.23
Factors associated with the appropriate use of asthma drugs. Can Respir J (2011) 1.18
Oral corticosteroids decrease eosinophil and CC chemokine expression but increase neutrophil, IL-8, and IFN-gamma-inducible protein 10 expression in asthmatic airway mucosa. J Allergy Clin Immunol (2005) 1.16
Evaluation of a program aimed at increasing referrals for asthma education of patients consulting at the emergency department for acute asthma. Chest (2004) 1.16
The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airway responses and airway inflammation in subjects with atopic asthma. J Allergy Clin Immunol (2003) 1.13
Thymic stromal lymphopoietin-induced human asthmatic airway epithelial cell proliferation through an IL-13-dependent pathway. J Allergy Clin Immunol (2010) 1.13
Impact of the loss of Hoxa5 function on lung alveogenesis. Am J Pathol (2006) 1.12
Influence of cigarette smoke on the arginine pathway in asthmatic airways: increased expression of arginase I. J Allergy Clin Immunol (2007) 1.10
Asthma and the elite athlete: summary of the International Olympic Committee's consensus conference, Lausanne, Switzerland, January 22-24, 2008. J Allergy Clin Immunol (2008) 1.08
CCR3 expression and function in asthmatic airway smooth muscle cells. J Immunol (2005) 1.08
Tools for assessing outcomes in studies of chronic cough: CHEST guideline and expert panel report. Chest (2015) 1.07
Diisocyanate asthma and gene-environment interactions with IL4RA, CD-14, and IL-13 genes. Ann Allergy Asthma Immunol (2006) 1.06
Pleural effusions following cardiac surgery: prevalence, risk factors, and clinical features. Chest (2009) 1.02
Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: role of MAPKs (ERK1/2, p38, and JNK) and STAT3 pathways. J Immunol (2010) 1.02
Immunostimulatory sequences regulate interferon-inducible genes but not allergic airway responses. Am J Respir Crit Care Med (2006) 1.02
Asthma and sleep apnea in patients with morbid obesity: outcome after bariatric surgery. Obes Surg (2004) 1.00
Canadian Thoracic Society: Presenting a new process for clinical practice guideline production. Can Respir J (2009) 1.00
Interleukin-18 and gamma interferon production by oral epithelial cells in response to exposure to Candida albicans or lipopolysaccharide stimulation. Infect Immun (2002) 0.97
The determinants of prevalence of health complaints among young competitive swimmers. Int Arch Occup Environ Health (2006) 0.96
Canadian Thoracic Society Asthma Committee commentary on long-acting beta-2 agonist use for asthma in Canada. Can Respir J (2010) 0.96
Increased p53 level, Bax/Bcl-x(L) ratio, and TRAIL receptor expression in human emphysema. Am J Respir Crit Care Med (2008) 0.96
Anti-inflammatory effect of pre-elafin in lipopolysaccharide-induced acute lung inflammation. Biol Chem (2002) 0.96
Adjustable maintenance dosing with budesonide/formoterol reduces asthma exacerbations compared with traditional fixed dosing: a five-month multicentre Canadian study. Can Respir J (2003) 0.95
Body mass index and response to asthma therapy: fluticasone propionate/salmeterol versus montelukast. J Asthma (2010) 0.95
Tumor necrosis factor-alpha expression in uvular tissues differs between snorers and apneic patients. Chest (2008) 0.93
CTNNA3 (α-catenin) gene variants are associated with diisocyanate asthma: a replication study in a Caucasian worker population. Toxicol Sci (2012) 0.93
Understanding allergic asthma from allergen inhalation tests. Can Respir J (2007) 0.93
IL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells. Respir Res (2013) 0.92
Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production. PLoS One (2012) 0.91
Inhaled allergen bronchoprovocation tests. J Allergy Clin Immunol (2013) 0.91
IL-16 activates plasminogen-plasmin system and promotes human eosinophil migration into extracellular matrix via CCR3-chemokine-mediated signaling and by modulating CD4 eosinophil expression. J Immunol (2004) 0.90
A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma. J Allergy Clin Immunol (2010) 0.90
Coumarinic derivatives show anti-inflammatory effects on alveolar macrophages, but their anti-elastase activity is essential to reduce lung inflammation in vivo. Int Immunopharmacol (2008) 0.90
Respiratory health of elite athletes - preventing airway injury: a critical review. Br J Sports Med (2012) 0.90
Influence of weight and sleep apnea status on immunologic and structural features of the uvula. Am J Respir Crit Care Med (2004) 0.89
Alveolar macrophage subpopulations in bronchoalveolar lavage and induced sputum of asthmatic and control subjects. J Asthma (2009) 0.89
Canadian Thoracic Society 2012 guideline update: Diagnosis and management of asthma in preschoolers, children and adults: executive summary. Can Respir J (2012) 0.89
Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. Respir Res (2011) 0.89
Montelukast regulates eosinophil protease activity through a leukotriene-independent mechanism. J Allergy Clin Immunol (2006) 0.89
Mast cells regulate procollagen I (alpha 1) production by bronchial fibroblasts derived from subjects with asthma through IL-4/IL-4 delta 2 ratio. J Allergy Clin Immunol (2006) 0.89
Symposium on obesity and asthma - November 2, 2006. Can Respir J (2007) 0.89
Polymorphisms in the interleukin-22 receptor alpha-1 gene are associated with severe chronic rhinosinusitis. Otolaryngol Head Neck Surg (2009) 0.89
Obesity, allergy and immunology. J Allergy Clin Immunol (2005) 0.88
Pan-Canadian REspiratory STandards INitiative for Electronic Health Records (PRESTINE): 2011 national forum proceedings. Can Respir J (2012) 0.88
Fibroblast growth factor-2 is a sputum remodeling biomarker of severe asthma. J Asthma (2013) 0.88
Are questionnaires on respiratory symptoms reliable predictors of airway hyperresponsiveness in athletes and sedentary subjects? J Asthma (2003) 0.88
Asthma and exercise-induced bronchoconstriction in athletes. N Engl J Med (2015) 0.88
Decreased miR-192 expression in peripheral blood of asthmatic individuals undergoing an allergen inhalation challenge. BMC Genomics (2012) 0.87
TGF-beta suppresses EGF-induced MAPK signaling and proliferation in asthmatic epithelial cells. Am J Respir Cell Mol Biol (2007) 0.87
Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects. Respir Res (2011) 0.87
Comparison of two in vitro models of cigarette smoke exposure. Inhal Toxicol (2009) 0.87
Genetic variations in taste receptors are associated with chronic rhinosinusitis: a replication study. Int Forum Allergy Rhinol (2014) 0.87
Obesity and asthma control in an urban population. J Allergy Clin Immunol (2010) 0.86
Efficacy and safety of mometasone furoate administered once-daily in the evening in patients with persistent asthma dependent on inhaled corticosteroids. Curr Med Res Opin (2005) 0.86
Cartography of emergency department visits for asthma - targeting high-morbidity populations. Can Respir J (2004) 0.86
Effects of whole cigarette smoke on human gingival fibroblast adhesion, growth, and migration. J Toxicol Environ Health A (2011) 0.86
Active smoking status in chronic rhinosinusitis is associated with higher serum markers of inflammation and lower serum eosinophilia. Int Forum Allergy Rhinol (2014) 0.85
Montelukast treatment attenuates the increase in myofibroblasts following low-dose allergen challenge. Chest (2006) 0.85
The relationships between atopy, rhinitis and asthma: pathophysiological considerations. Curr Opin Allergy Clin Immunol (2003) 0.85
Characterization of human pre-elafin mutants: full antipeptidase activity is essential to preserve lung tissue integrity in experimental emphysema. Biochem J (2007) 0.85
The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways. Biol Open (2012) 0.84
Investigation of occupational asthma: Do clinicians fail to identify relevant occupational exposures? Can Respir J (2015) 0.84
Leptin and adiponectin in obese and non-obese subjects with asthma. Biomarkers (2011) 0.84
Respiratory guidelines implementation in Canada. Can Respir J (2007) 0.83
Characteristics and medical resource use of asthmatic subjects with and without work-related asthma. J Allergy Clin Immunol (2007) 0.83
Airway remodeling and inflammation in competitive swimmers training in indoor chlorinated swimming pools. J Allergy Clin Immunol (2011) 0.83
Increased local levels of granulocyte colony-stimulating factor are associated with the beneficial effect of pre-elafin (SKALP/trappin-2/WAP3) in experimental emphysema. Biol Chem (2006) 0.83