Published in J Neuropathol Exp Neurol on August 01, 2002
The significance of neuroinflammation in understanding Alzheimer's disease. J Neural Transm (Vienna) (2006) 1.55
A reevaluation of tetraploidy in the Alzheimer's disease brain. Neurodegener Dis (2009) 1.47
The interaction of the atm genotype with inflammation and oxidative stress. PLoS One (2014) 1.45
Cell division in the CNS: protective response or lethal event in post-mitotic neurons? Biochim Biophys Acta (2006) 1.41
Cell cycle molecules define a pathway required for neuron death in development and disease. Biochim Biophys Acta (2006) 1.35
AAV-tau mediates pyramidal neurodegeneration by cell-cycle re-entry without neurofibrillary tangle formation in wild-type mice. PLoS One (2009) 1.23
Levels of CSF prostaglandin E2, cognitive decline, and survival in Alzheimer's disease. J Neurol Neurosurg Psychiatry (2005) 1.15
Cell-context specific role of the E2F/Rb pathway in development and disease. Glia (2010) 1.04
Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease. Aging (Albany NY) (2009) 1.01
PPARgamma pathway activation results in apoptosis and COX-2 inhibition in HepG2 cells. World J Gastroenterol (2003) 0.96
Neuronal cell cycle: the neuron itself and its circumstances. Cell Cycle (2015) 0.90
Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease. J Neuroinflammation (2005) 0.89
Ubiquitin C-terminal hydrolase L1 (UCH-L1) acts as a novel potentiator of cyclin-dependent kinases to enhance cell proliferation independently of its hydrolase activity. J Biol Chem (2013) 0.87
Cell-cycle markers in a transgenic mouse model of human tauopathy: increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1. Am J Pathol (2006) 0.84
Mitosis-specific phosphorylation of amyloid precursor protein at threonine 668 leads to its altered processing and association with centrosomes. Mol Neurodegener (2011) 0.83
Physiological and pathophysiological functions of cell cycle proteins in post-mitotic neurons: implications for Alzheimer's disease. Acta Neuropathol (2015) 0.79
The expression of apoptosis inducing factor (AIF) is associated with aging-related cell death in the cortex but not in the hippocampus in the TgCRND8 mouse model of Alzheimer's disease. BMC Neurosci (2014) 0.78
Targeting gonadotropins: an alternative option for Alzheimer disease treatment. J Biomed Biotechnol (2006) 0.78
Cell cycle related signaling in Neuro2a cells proceeds via the receptor for advanced glycation end products. J Neural Transm (Vienna) (2007) 0.77
Overexpression of Cell Cycle Proteins of Peripheral Lymphocytes in Patients with Alzheimer's Disease. Psychiatry Investig (2015) 0.76
ATM and the epigenetics of the neuronal genome. Mech Ageing Dev (2013) 0.75
Wnt5a Promotes Cortical Neuron Survival by Inhibiting Cell-Cycle Activation. Front Cell Neurosci (2017) 0.75
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathol (2009) 4.73
Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathol (2008) 4.73
Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis. JAMA (2010) 4.57
Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study. J Am Geriatr Soc (2005) 4.01
Regional patterns of gene expression in human and chimpanzee brains. Genome Res (2004) 3.84
A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell (2009) 3.63
Routine use of the confusion assessment method for the intensive care unit: a multicenter study. Am J Respir Crit Care Med (2011) 2.97
Systemic infection and delirium: when cytokines and acetylcholine collide. Lancet (2010) 2.36
The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions. Brain (2012) 2.33
The cholinergic system in aging and neuronal degeneration. Behav Brain Res (2010) 2.23
Tissue transglutaminase is not a biochemical marker for Alzheimer's disease. Neurobiol Aging (2013) 2.00
The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus. Am J Pathol (2009) 1.92
The effect of amyloid associated proteins on the expression of genes involved in amyloid-β clearance by adult human astrocytes. Exp Neurol (2011) 1.85
Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease? Free Radic Biol Med (2008) 1.83
Inflammatory markers in AD and MCI patients with different biomarker profiles. Neurobiol Aging (2008) 1.82
The pathology of multiple sclerosis is location-dependent: no significant complement activation is detected in purely cortical lesions. J Neuropathol Exp Neurol (2005) 1.76
The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies. J Pathol (2012) 1.76
Serum lipids and hippocampal volume: the link to Alzheimer's disease? Ann Neurol (2004) 1.72
Neuroinflammation - an early event in both the history and pathogenesis of Alzheimer's disease. Neurodegener Dis (2010) 1.66
Aneuploidy and DNA replication in the normal human brain and Alzheimer's disease. J Neurosci (2007) 1.52
How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes. Aging Cell (2004) 1.51
Impact of cellular senescence signature on ageing research. Ageing Res Rev (2010) 1.47
Phenotypic characterization of hypomyelination and congenital cataract. Ann Neurol (2007) 1.46
Prion protein amyloidosis with divergent phenotype associated with two novel nonsense mutations in PRNP. Acta Neuropathol (2009) 1.39
Re-expression of cell cycle proteins induces neuronal cell death during Alzheimer's disease. J Alzheimers Dis (2002) 1.34
Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy. Antioxid Redox Signal (2011) 1.29
Lipoprotein receptor-related protein-1 mediates amyloid-beta-mediated cell death of cerebrovascular cells. Am J Pathol (2007) 1.28
Vascular factors and markers of inflammation in offspring with a parental history of late-onset Alzheimer disease. Arch Gen Psychiatry (2009) 1.27
Risk factors and prediction of postoperative delirium in elderly hip-surgery patients: implementation and validation of a medical risk factor model. J Am Geriatr Soc (2006) 1.25
Frequency of ubiquitin and FUS-positive, TDP-43-negative frontotemporal lobar degeneration. J Neurol (2009) 1.22
Long-term cognitive outcome of delirium in elderly hip surgery patients. A prospective matched controlled study over two and a half years. Dement Geriatr Cogn Disord (2008) 1.18
Selective cell death of hyperploid neurons in Alzheimer's disease. Am J Pathol (2010) 1.15
Age- and stage-dependent accumulation of advanced glycation end products in intracellular deposits in normal and Alzheimer's disease brains. Cereb Cortex (2004) 1.14
Microglia activation in sepsis: a case-control study. J Neuroinflammation (2007) 1.13
Pre-operative inflammatory markers and the risk of postoperative delirium in elderly patients. Int J Geriatr Psychiatry (2008) 1.12
Neuroinflammation in delirium: a postmortem case-control study. Rejuvenation Res (2011) 1.11
Astrocytic A beta 1-42 uptake is determined by A beta-aggregation state and the presence of amyloid-associated proteins. Glia (2010) 1.10
Structural correlates of mild cognitive impairment. Neurobiol Aging (2004) 1.09
Aberrant expression of NOS isoforms in Alzheimer's disease is structurally related to nitrotyrosine formation. Brain Res (2002) 1.08
Different dendrite and dendritic spine alterations in basal and apical arbors in mutant human amyloid precursor protein transgenic mice. Brain Res (2006) 1.08
Binding and uptake of A beta1-42 by primary human astrocytes in vitro. Glia (2009) 1.06
Tau gene (MAPT) sequence variation among primates. Gene (2004) 1.06
Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brains. Neurobiol Aging (2006) 1.05
AbetaPP induces cdk5-dependent tau hyperphosphorylation in transgenic mice Tg2576. J Alzheimers Dis (2002) 1.05
Enhanced capillary amyloid angiopathy-associated pathology in Tg-SwDI mice with deleted nitric oxide synthase 2. Stroke (2010) 1.05
Perineuronal nets potentially protect against oxidative stress. Exp Neurol (2004) 1.03
Sodium valproate in the treatment of aggressive behavior in patients with dementia--a randomized placebo controlled clinical trial. Int J Geriatr Psychiatry (2002) 1.03
C1-inhibitor protects against brain ischemia-reperfusion injury via inhibition of cell recruitment and inflammation. Neurobiol Dis (2005) 1.03
Tau oligomers impair artificial membrane integrity and cellular viability. J Biol Chem (2012) 1.03
Early symptoms in the prodromal phase of delirium: a prospective cohort study in elderly patients undergoing hip surgery. Am J Geriatr Psychiatry (2007) 1.02
Hibernation model of tau phosphorylation in hamsters: selective vulnerability of cholinergic basal forebrain neurons - implications for Alzheimer's disease. Eur J Neurosci (2007) 1.02
Activation of the unfolded protein response is an early event in Alzheimer's and Parkinson's disease. Neurodegener Dis (2012) 1.01
Neuroprotection against iron-induced cell death by perineuronal nets - an in vivo analysis of oxidative stress. Am J Neurodegener Dis (2012) 1.01
Amyloid beta plaque-associated proteins C1q and SAP enhance the Abeta1-42 peptide-induced cytokine secretion by adult human microglia in vitro. Acta Neuropathol (2002) 1.01
DNA polymerase-beta is expressed early in neurons of Alzheimer's disease brain and is loaded into DNA replication forks in neurons challenged with beta-amyloid. J Neurosci (2006) 0.99
MRI and cerebrospinal fluid biomarkers for predicting progression to Alzheimer's disease in patients with mild cognitive impairment: a diagnostic accuracy study. BMJ Open (2013) 0.99
Involvement of perineuronal and perisynaptic extracellular matrix in Alzheimer's disease neuropathology. Brain Pathol (2012) 0.99
The neuroinflammatory response in plaques and amyloid angiopathy in Alzheimer's disease: therapeutic implications. Curr Drug Targets CNS Neurol Disord (2005) 0.99
Neuronal activation of Ras regulates synaptic connectivity. Eur J Neurosci (2004) 0.99
The pre-eclampsia gene STOX1 controls a conserved pathway in placenta and brain upregulated in late-onset Alzheimer's disease. J Alzheimers Dis (2010) 0.99
Serial CSF sampling in Alzheimer's disease: specific versus non-specific markers. Neurobiol Aging (2011) 0.98
Systematic analysis of gene expression in human brains before and after death. Genome Biol (2005) 0.98
Non-steroidal anti-inflammatory drugs and cyclooxygenase in Alzheimer's disease. Curr Drug Targets (2003) 0.98
Human prion diseases in the Netherlands (1998-2009): clinical, genetic and molecular aspects. PLoS One (2012) 0.98
C4b-binding protein in Alzheimer's disease: binding to Abeta1-42 and to dead cells. Mol Immunol (2008) 0.97
Mortality associated with delirium after hip-surgery: a 2-year follow-up study. Age Ageing (2011) 0.97
Neuronal COX-2 expression and phosphorylation of pRb precede p38 MAPK activation and neurofibrillary changes in AD temporal cortex. Neurobiol Dis (2004) 0.96
Transglutaminases and transglutaminase-catalyzed cross-links colocalize with the pathological lesions in Alzheimer's disease brain. Brain Pathol (2008) 0.96
Microbleeds relate to altered amyloid-β metabolism in Alzheimer's disease. Neurobiol Aging (2011) 0.96
The role of cyclo-oxygenase 1 and 2 activity in prostaglandin E(2) secretion by cultured human adult microglia: implications for Alzheimer's disease. Brain Res (2002) 0.96
BACE1 activity in cerebrospinal fluid and its relation to markers of AD pathology. J Alzheimers Dis (2010) 0.95
Preoperative cerebrospinal fluid cytokine levels and the risk of postoperative delirium in elderly hip fracture patients. J Neuroinflammation (2013) 0.95
Inducible neuronal expression of transgenic TGF-beta1 in vivo: dissection of short-term and long-term effects. Eur J Neurosci (2005) 0.94
Expression of embryonic tau protein isoforms persist during adult neurogenesis in the hippocampus. Hippocampus (2007) 0.94
Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer's disease: a long-term follow up study. J Neural Transm (Vienna) (2011) 0.94
Microglia kill amyloid-beta1-42 damaged neurons by a CD14-dependent process. Neuroreport (2004) 0.93
Steroid responsive encephalopathy in cerebral amyloid angiopathy: a case report and review of evidence for immunosuppressive treatment. J Neuroinflammation (2010) 0.92
Inhibitory effect of minocycline on amyloid beta fibril formation and human microglial activation. Glia (2006) 0.92
Effect of pseudophosphorylation and cross-linking by lipid peroxidation and advanced glycation end product precursors on tau aggregation and filament formation. J Biol Chem (2006) 0.92
Association of vascular factors with apathy in community-dwelling elderly individuals. Arch Gen Psychiatry (2012) 0.91
Value of diagnostic tests to predict conversion to Alzheimer's disease in young and old patients with amnestic mild cognitive impairment. J Alzheimers Dis (2012) 0.91
Linking cell-cycle dysfunction in Alzheimer's disease to a failure of synaptic plasticity. Biochim Biophys Acta (2006) 0.91