Published in J Biochem on August 01, 2002
Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness. Mol Biol Cell (2005) 1.69
Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis. Mol Biol Cell (2011) 1.54
Serotonin-, protein kinase C-, and Hic-5-associated redistribution of the platelet serotonin transporter. J Biol Chem (2006) 1.23
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin. Cell Signal (2007) 1.23
Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA. PLoS One (2012) 1.00
Diverse roles for the paxillin family of proteins in cancer. Genes Cancer (2012) 0.98
HIC-5: A Mobile Molecular Scaffold Regulating the Anchorage Dependence of Cell Growth. Int J Cell Biol (2011) 0.81
Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulation. J Cell Sci (2016) 0.79
Cyclic Nucleotide-dependent Protein Kinases Target ARHGAP17 and ARHGEF6 Complexes in Platelets. J Biol Chem (2015) 0.77
The role of Nox-mediated oxidation in the regulation of cytoskeletal dynamics. Curr Pharm Des (2015) 0.77
Hic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase. J Cell Sci (2016) 0.77
20-HETE Signals Through G Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension. Circ Res (2017) 0.76
Neuronal correlates of goal-based motor selection in the prefrontal cortex. Science (2003) 3.53
Invasive potential induced under long-term oxidative stress in mammary epithelial cells. Cancer Res (2004) 1.66
The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells. Immunity (2006) 1.53
A dietary restriction influences the progression but not the initiation of MSG-Induced nonalcoholic steatohepatitis. J Med Food (2014) 1.41
Structural characterization of TSC-36/Flik: analysis of two charge isoforms. J Biol Chem (2003) 1.33
Circulating progenitor cells contribute to neointimal formation in nonirradiated chimeric mice. FASEB J (2007) 1.22
Uni-axial stretching regulates intracellular localization of Hic-5 expressed in smooth-muscle cells in vivo. J Cell Sci (2005) 1.20
Hic-5 communicates between focal adhesions and the nucleus through oxidant-sensitive nuclear export signal. Mol Biol Cell (2003) 1.19
Monosodium glutamate (MSG): a villain and promoter of liver inflammation and dysplasia. J Autoimmun (2008) 1.08
Impact of salusin-alpha and -beta on human macrophage foam cell formation and coronary atherosclerosis. Circulation (2008) 1.04
A LIM protein, Hic-5, functions as a potential coactivator for Sp1. J Cell Biochem (2004) 1.02
Type 2 diabetes mellitus in obese mouse model induced by monosodium glutamate. Exp Anim (2006) 1.02
IL-4-induced GATA-3 expression is a time-restricted instruction switch for Th2 cell differentiation. J Immunol (2004) 0.99
The IL-4 production capability of different strains of naive CD4(+) T cells controls the direction of the T(h) cell response. Int Immunol (2002) 0.96
Hic-5 deficiency enhances mechanosensitive apoptosis and modulates vascular remodeling. J Mol Cell Cardiol (2010) 0.96
Gene expression profiling identifies a role for CHOP during inhibition of the mitochondrial respiratory chain. J Biochem (2009) 0.95
Effects of bezafibrate in nonalcoholic steatohepatitis model mice with monosodium glutamate-induced metabolic syndrome. Eur J Pharmacol (2011) 0.92
Insulin resistance and low sympathetic nerve activity in the Tsumura Suzuki obese diabetic mouse: a new model of spontaneous type 2 diabetes mellitus and obesity. Metabolism (2006) 0.91
Inhibition of excitatory neuronal cell death by cell-permeable calcineurin autoinhibitory peptide. J Neurochem (2003) 0.90
Diabetic complications in a new animal model (TSOD mouse) of spontaneous NIDDM with obesity. Exp Anim (2005) 0.90
Origins of retinal intrinsic signals: a series of experiments on retinas of macaque monkeys. Jpn J Ophthalmol (2009) 0.89
Importance of mitochondrial dysfunction in oxidative stress response: A comparative study of gene expression profiles. Free Radic Res (2011) 0.89
Spontaneous onset of nonalcoholic steatohepatitis and hepatocellular carcinoma in a mouse model of metabolic syndrome. Lab Invest (2012) 0.88
Anthracyclines, small-molecule inhibitors of hypoxia-inducible factor-1 alpha activation. Biol Pharm Bull (2006) 0.87
Involvement of FAK and PTP-PEST in the regulation of redox-sensitive nuclear-cytoplasmic shuttling of a LIM protein, Hic-5. Antioxid Redox Signal (2005) 0.87
Oligomerizing potential of a focal adhesion LIM protein Hic-5 organizing a nuclear-cytoplasmic shuttling complex. J Biol Chem (2006) 0.86
Transcriptional activation of the c-fos gene by a LIM protein, Hic-5. Biochem Biophys Res Commun (2002) 0.86
Downregulation of hepatocyte nuclear factor-4alpha and its role in regulation of gene expression by TGF-beta in mammary epithelial cells. Exp Cell Res (2008) 0.85
BMP2 differentially regulates the expression of Gremlin1 and Gremlin2, the negative regulators of BMP function, during osteoblast differentiation. Calcif Tissue Int (2012) 0.84
An empirical analysis of a telehealth system in terms of cost-sharing. J Telemed Telecare (2003) 0.84
Dose dependent development of diabetes mellitus and non-alcoholic steatohepatitis in monosodium glutamate-induced obese mice. Life Sci (2009) 0.84
Specific inhibition of hypoxia-inducible factor (HIF)-1 alpha activation and of vascular endothelial growth factor (VEGF) production by flavonoids. Biol Pharm Bull (2003) 0.83
Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage dependence of cell growth and survival. Mol Biol Cell (2008) 0.83
Induction of p16/INK4a gene expression and cellular senescence by toyocamycin. Biol Pharm Bull (2002) 0.83
Inhibition of angiogenesis and HIF-1alpha activity by antimycin A1. Biol Pharm Bull (2006) 0.82
Hic-5, an adaptor protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo. Biochem Biophys Res Commun (2008) 0.82
Detection of allelic imbalance in the gene expression of hMSH2 or RB1 in lymphocytes from pedigrees of hereditary, nonpolyposis, colorectal cancer and retinoblastoma by an RNA difference plot. J Hum Genet (2004) 0.82
Induction of matrix metalloproteinase gene expression in an endothelial cell line by direct interaction with malignant cells. Cancer Sci (2007) 0.82
HIC-5: A Mobile Molecular Scaffold Regulating the Anchorage Dependence of Cell Growth. Int J Cell Biol (2011) 0.81
HIF-1-dependent VEGF reporter gene assay by a stable transformant of CHO cells. Biol Pharm Bull (2003) 0.80
Possible involvement of hic-5, a focal adhesion protein, in the differentiation of C2C12 myoblasts. Cell Struct Funct (2002) 0.80
Bioluminescent enzyme immunoassay for the detection of norovirus capsid antigen. Clin Vaccine Immunol (2012) 0.79
Functional topography of rod and cone photoreceptors in macaque retina determined by retinal densitometry. Invest Ophthalmol Vis Sci (2012) 0.78
Novel snapshot imaging of photoreceptor bleaching in macaque and human retinas. Jpn J Ophthalmol (2010) 0.77
Induction of p16INK4a transcription and of cellular senescence by aclacinomycin-derivatives and cardiac glycosides. Biol Pharm Bull (2002) 0.77
Critical roles of the cAMP-responsive element-binding protein-mediated pathway in disorganized epithelial phenotypes caused by mitochondrial dysfunction. Cancer Sci (2012) 0.76
BMP-2 Induced Expression of Alx3 That Is a Positive Regulator of Osteoblast Differentiation. PLoS One (2013) 0.76
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug Metab Dispos (2011) 0.76
A HIC-5- and KLF4-dependent mechanism transactivates p21(Cip1) in response to anchorage loss. J Biol Chem (2012) 0.76
Advantages and disadvantages of hyperbaric oxygen treatment in mice with obesity hyperlipidemia and steatohepatitis. ScientificWorldJournal (2011) 0.75
Redox control of protein trafficking. Antioxid Redox Signal (2005) 0.75
[Roles of BPH impact index in the evaluation of impaired urination in patients with BPH]. Nihon Hinyokika Gakkai Zasshi (2005) 0.75
In vitro evaluation of the potential for drug-induced toxicity based on (35)S-labeled glutathione adduct formation and daily dose. Bioanalysis (2012) 0.75
[Efficacy of preventive treatment for delayed emesis induced by FOLFOX4 chemotherapy]. Yakugaku Zasshi (2009) 0.75
Electrochemical sensor with flavin-containing monooxygenase for triethylamine solution. Anal Bioanal Chem (2007) 0.75
[A review of the position adopted by patients when acquiring images of the base of the hamate hook]. Nihon Hoshasen Gijutsu Gakkai Zasshi (2014) 0.75
[Regulation of cellular phenotypes by Hic-5 that localizes both in the focal adhesion and in the nucleus]. Seikagaku (2002) 0.75
A study of cardiovascular function in Tsumura Suzuki obese diabetes, a new model mouse of type 2 diabetes. Biol Pharm Bull (2010) 0.75
Neural correlates of second-language communication and the effect of language anxiety. Neuropsychologia (2016) 0.75
Hexameric subphthalocyanine rosette. Dalton Trans (2011) 0.75
[Home-medical-care and IT--for the further diffusion of the tele-health system]. Gan To Kagaku Ryoho (2002) 0.75
[Evaluation of Norovirus Detection Method Based on a Newly Developed Bioluminescent Enzyme Immunoassay (BLEIA) System]. Kansenshogaku Zasshi (2015) 0.75
Hygrolidin induces p21 expression and abrogates cell cycle progression at G1 and S phases. Biochem Biophys Res Commun (2002) 0.75
Functional map of orientation tuning width and specificity. Neuroreport (2007) 0.75