Published in Science on August 02, 2002
Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol (2014) 10.04
Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease. J Clin Invest (2009) 6.70
Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev (2008) 4.38
Relations and interactions between cranial mesoderm and neural crest populations. J Anat (2005) 2.26
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proc Natl Acad Sci U S A (2003) 2.14
Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells. Proc Natl Acad Sci U S A (2003) 1.93
Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest. Cell Stem Cell (2012) 1.80
Assembling neural crest regulatory circuits into a gene regulatory network. Annu Rev Cell Dev Biol (2010) 1.72
Mesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation. J Cell Biol (2004) 1.56
Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest cells. Proc Natl Acad Sci U S A (2011) 1.56
Cranial neural crest cells on the move: their roles in craniofacial development. Am J Med Genet A (2010) 1.55
Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling. J Cell Biol (2005) 1.44
Induction of neural crest in Xenopus by transcription factor AP2alpha. Proc Natl Acad Sci U S A (2003) 1.43
Craniofacial birth defects: The role of neural crest cells in the etiology and pathogenesis of Treacher Collins syndrome and the potential for prevention. Am J Med Genet A (2010) 1.38
Modeling neural crest induction, melanocyte specification, and disease-related pigmentation defects in hESCs and patient-specific iPSCs. Cell Rep (2013) 1.36
The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction. Development (2009) 1.31
Current perspectives of the signaling pathways directing neural crest induction. Cell Mol Life Sci (2012) 1.30
Distinct Wnt members regulate the hierarchical morphogenesis of skin regions (spinal tract) and individual feathers. Mech Dev (2004) 1.26
Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways. Development (2008) 1.26
Establishing neural crest identity: a gene regulatory recipe. Development (2015) 1.22
Zebrafish narrowminded disrupts the transcription factor prdm1 and is required for neural crest and sensory neuron specification. Dev Biol (2005) 1.16
Differential requirements of BMP and Wnt signalling during gastrulation and neurulation define two steps in neural crest induction. Development (2009) 1.14
Induction of the neural crest state: control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions. Dev Biol (2012) 1.11
A negative modulatory role for rho and rho-associated kinase signaling in delamination of neural crest cells. Neural Dev (2008) 1.10
Ectodermal Wnt/β-catenin signaling shapes the mouse face. Dev Biol (2010) 1.10
Fgf8a induces neural crest indirectly through the activation of Wnt8 in the paraxial mesoderm. Development (2008) 1.08
Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain. Development (2007) 1.07
Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos. Development (2010) 1.07
Early acquisition of neural crest competence during hESCs neuralization. PLoS One (2010) 1.05
What is bad in cancer is good in the embryo: importance of EMT in neural crest development. Semin Cell Dev Biol (2012) 1.05
Directed differentiation of human pluripotent cells to neural crest stem cells. Nat Protoc (2013) 1.04
Fate map and morphogenesis of presumptive neural crest and dorsal neural tube. Dev Biol (2009) 1.04
Dynamic alterations in gene expression after Wnt-mediated induction of avian neural crest. Mol Biol Cell (2005) 1.03
Setting appropriate boundaries: fate, patterning and competence at the neural plate border. Dev Biol (2013) 1.02
Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population. Dev Biol (2011) 1.01
A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron (2012) 0.96
FGF/MAPK signaling is required in the gastrula epiblast for avian neural crest induction. Development (2011) 0.95
Early development of the central and peripheral nervous systems is coordinated by Wnt and BMP signals. PLoS One (2008) 0.95
Palate morphogenesis: current understanding and future directions. Birth Defects Res C Embryo Today (2010) 0.94
Neural crest and placode interaction during the development of the cranial sensory system. Dev Biol (2014) 0.93
Wnt agonist attenuates liver injury and improves survival after hepatic ischemia/reperfusion. Shock (2013) 0.92
Extracellular matrix protein anosmin promotes neural crest formation and regulates FGF, BMP, and WNT activities. Dev Cell (2012) 0.92
Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev (2009) 0.92
Diversification of the expression patterns and developmental functions of the dishevelled gene family during chordate evolution. Dev Dyn (2009) 0.92
Mechanisms driving neural crest induction and migration in the zebrafish and Xenopus laevis. Cell Adh Migr (2011) 0.91
BMP, Wnt and FGF signals are integrated through evolutionarily conserved enhancers to achieve robust expression of Pax3 and Zic genes at the zebrafish neural plate border. Development (2012) 0.91
Pax3 and Zic1 drive induction and differentiation of multipotent, migratory, and functional neural crest in Xenopus embryos. Proc Natl Acad Sci U S A (2013) 0.90
Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells. Mol Cancer (2011) 0.90
Kctd15 inhibits neural crest formation by attenuating Wnt/beta-catenin signaling output. Development (2010) 0.90
Specification of neural crest into sensory neuron and melanocyte lineages. Dev Biol (2012) 0.88
Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning. Dev Biol (2012) 0.88
FGF and retinoic acid activity gradients control the timing of neural crest cell emigration in the trunk. J Cell Biol (2011) 0.87
Trigenic neural crest-restricted Smad7 over-expression results in congenital craniofacial and cardiovascular defects. Dev Biol (2010) 0.87
Rbms3 functions in craniofacial development by posttranscriptionally modulating TGF-β signaling. J Cell Biol (2012) 0.86
Rohon-Beard sensory neurons are induced by BMP4 expressing non-neural ectoderm in Xenopus laevis. Dev Biol (2007) 0.86
Development. Riding the crest of the Wnt signaling wave. Science (2002) 0.86
FGF signaling transforms non-neural ectoderm into neural crest. Dev Biol (2012) 0.86
Rabconnectin-3a regulates vesicle endocytosis and canonical Wnt signaling in zebrafish neural crest migration. PLoS Biol (2014) 0.85
Activated β-catenin forces N2A cell-derived neurons back to tumor-like neuroblasts and positively correlates with a risk for human neuroblastoma. Int J Biol Sci (2012) 0.85
The heart-placenta axis in the first month of pregnancy: induction and prevention of cardiovascular birth defects. J Pregnancy (2013) 0.84
Folate rescues lithium-, homocysteine- and Wnt3A-induced vertebrate cardiac anomalies. Dis Model Mech (2009) 0.84
Asymmetric requirement of surface epithelial β-catenin during the upper and lower jaw development. Dev Dyn (2012) 0.83
Recycling signals in the neural crest. J Biol (2005) 0.83
Wnt signaling interacts with bmp and edn1 to regulate dorsal-ventral patterning and growth of the craniofacial skeleton. PLoS Genet (2014) 0.83
Osteoblasts Have a Neural Origin in Heterotopic Ossification. Clin Orthop Relat Res (2015) 0.83
Early vertebrate evolution of the TATA-binding protein, TBP. Mol Biol Evol (2003) 0.83
Late-emigrating neural crest cells in the roof plate are restricted to a sensory fate by GDF7. Proc Natl Acad Sci U S A (2005) 0.83
Differentiation and regenerative capacities of human odontoma-derived mesenchymal cells. Differentiation (2008) 0.83
Early neural crest induction requires an initial inhibition of Wnt signals. Dev Biol (2012) 0.83
Sox2 acts as a rheostat of epithelial to mesenchymal transition during neural crest development. Front Physiol (2014) 0.82
A systematic survey of expression and function of zebrafish frizzled genes. PLoS One (2013) 0.82
The adenomatous polyposis coli tumor suppressor and Wnt signaling in the regulation of apoptosis. Adv Exp Med Biol (2009) 0.82
The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus. PLoS Genet (2015) 0.82
Yap and Taz play a crucial role in neural crest-derived craniofacial development. Development (2015) 0.81
Fate mapping of neural crest cells during eye development using a protein 0 promoter-driven transgenic technique. Graefes Arch Clin Exp Ophthalmol (2008) 0.81
Neural crest specification by noncanonical Wnt signaling and PAR-1. Development (2011) 0.81
WNT/β-catenin signaling mediates human neural crest induction via a pre-neural border intermediate. Development (2016) 0.80
Multifaceted signaling regulators of chondrogenesis: Implications in cartilage regeneration and tissue engineering. Genes Dis (2015) 0.80
Anterior Hox genes interact with components of the neural crest specification network to induce neural crest fates. Stem Cells (2011) 0.80
Axud1 Integrates Wnt Signaling and Transcriptional Inputs to Drive Neural Crest Formation. Dev Cell (2015) 0.79
An intermediate level of BMP signaling directly specifies cranial neural crest progenitor cells in zebrafish. PLoS One (2011) 0.79
An essential role for heat shock transcription factor binding protein 1 (HSBP1) during early embryonic development. Dev Biol (2013) 0.79
Suppression of histone deacetylation promotes the differentiation of human pluripotent stem cells towards neural progenitor cells. BMC Biol (2014) 0.79
The molecular basis of craniofacial placode development. Wiley Interdiscip Rev Dev Biol (2016) 0.78
GSK3 and Polo-like kinase regulate ADAM13 function during cranial neural crest cell migration. Mol Biol Cell (2014) 0.78
Evolutionarily conserved role for SoxC genes in neural crest specification and neuronal differentiation. Dev Biol (2014) 0.77
The effect on cell growth by Wnt1 RNAi in human neuroblastoma SH-SY5Y cell line. Pediatr Surg Int (2009) 0.77
Delamination of neural crest cells requires transient and reversible Wnt inhibition mediated by Dact1/2. Development (2016) 0.76
Zebrafish Zic2a and Zic2b regulate neural crest and craniofacial development. Dev Biol (2013) 0.76
A novel spalt gene expressed in branchial arches affects the ability of cranial neural crest cells to populate sensory ganglia. Neuron Glia Biol (2004) 0.76
Roles of Wnt pathway genes wls, wnt9a, wnt5b, frzb and gpc4 in regulating convergent-extension during zebrafish palate morphogenesis. Development (2016) 0.76
Exploring the developmental mechanisms underlying Wolf-Hirschhorn Syndrome: Evidence for defects in neural crest cell migration. Dev Biol (2016) 0.75
Gene regulatory networks in embryonic stem cells and brain development. Birth Defects Res C Embryo Today (2009) 0.75
Regulatory Logic Underlying Diversification of the Neural Crest. Trends Genet (2017) 0.75
A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. Elife (2017) 0.75
Reprogramming Postnatal Human Epidermal Keratinocytes Toward Functional Neural Crest Fates. Stem Cells (2017) 0.75
Should I stay or should I go? Cadherin function and regulation in the neural crest. Genesis (2017) 0.75
Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci U S A (2003) 10.56
The amphioxus genome and the evolution of the chordate karyotype. Nature (2008) 8.03
Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease. J Clin Invest (2009) 6.70
A gene regulatory network orchestrates neural crest formation. Nat Rev Mol Cell Biol (2008) 4.00
A common somitic origin for embryonic muscle progenitors and satellite cells. Nature (2005) 3.40
The amphioxus genome illuminates vertebrate origins and cephalochordate biology. Genome Res (2008) 3.04
Specification of the neural crest occurs during gastrulation and requires Pax7. Nature (2006) 2.38
Gene-regulatory interactions in neural crest evolution and development. Dev Cell (2004) 2.34
Induction of the neural crest: a multigene process. Nat Rev Genet (2002) 2.26
Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling. Development (2005) 1.81
Assembling neural crest regulatory circuits into a gene regulatory network. Annu Rev Cell Dev Biol (2010) 1.72
Ancient evolutionary origin of the neural crest gene regulatory network. Dev Cell (2007) 1.71
Importance of SoxE in neural crest development and the evolution of the pharynx. Nature (2006) 1.69
Snail2 directly represses cadherin6B during epithelial-to-mesenchymal transitions of the neural crest. Development (2007) 1.58
Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells. Stem Cells Dev (2009) 1.56
Neural crest regulates myogenesis through the transient activation of NOTCH. Nature (2011) 1.55
WNT11 acts as a directional cue to organize the elongation of early muscle fibres. Nature (2008) 1.53
Neural crest specification: migrating into genomics. Nat Rev Neurosci (2003) 1.53
Myostatin promotes the terminal differentiation of embryonic muscle progenitors. Genes Dev (2008) 1.52
Axial patterning in cephalochordates and the evolution of the organizer. Nature (2007) 1.52
A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Genes Dev (2011) 1.48
Genomic code for Sox10 activation reveals a key regulatory enhancer for cranial neural crest. Proc Natl Acad Sci U S A (2010) 1.47
Wnt regulation of chondrocyte differentiation. J Cell Sci (2002) 1.44
Neuropilin 2/semaphorin 3F signaling is essential for cranial neural crest migration and trigeminal ganglion condensation. Dev Neurobiol (2007) 1.43
Lens specification is the ground state of all sensory placodes, from which FGF promotes olfactory identity. Dev Cell (2006) 1.39
The odontode explosion: the origin of tooth-like structures in vertebrates. Bioessays (2010) 1.38
Sonic hedgehog rescues cranial neural crest from cell death induced by ethanol exposure. Proc Natl Acad Sci U S A (2002) 1.37
Dissecting early regulatory relationships in the lamprey neural crest gene network. Proc Natl Acad Sci U S A (2008) 1.36
A two-step mechanism for myotome formation in chick. Dev Cell (2004) 1.34
Sox10 overexpression induces neural crest-like cells from all dorsoventral levels of the neural tube but inhibits differentiation. Dev Dyn (2005) 1.30
Amphioxus and lamprey AP-2 genes: implications for neural crest evolution and migration patterns. Development (2002) 1.27
Development and evolution of the migratory neural crest: a gene regulatory perspective. Curr Opin Genet Dev (2006) 1.27
Genomic analysis of neural crest induction. Development (2002) 1.26
Insights from the amphioxus genome on the origin of vertebrate neural crest. Genome Res (2008) 1.24
Segregation of lens and olfactory precursors from a common territory: cell sorting and reciprocity of Dlx5 and Pax6 expression. Dev Biol (2004) 1.24
Role of the hindbrain in dorsoventral but not anteroposterior axial specification of the inner ear. Development (2005) 1.24
Dual function of Slit2 in repulsion and enhanced migration of trunk, but not vagal, neural crest cells. J Cell Biol (2003) 1.24
Robo2-Slit1 dependent cell-cell interactions mediate assembly of the trigeminal ganglion. Nat Neurosci (2008) 1.23
FGFR4 signaling is a necessary step in limb muscle differentiation. Development (2002) 1.23
How to link ontologies and protein-protein interactions to literature: text-mining approaches and the BioCreative experience. Database (Oxford) (2012) 1.23
Early steps in neural crest specification. Semin Cell Dev Biol (2005) 1.21
Histone demethylase JmjD2A regulates neural crest specification. Dev Cell (2010) 1.20
A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration. Development (2004) 1.20
Neural crest contributions to the lamprey head. Development (2003) 1.17
In ovo electroporation of avian somites. Dev Dyn (2004) 1.17
Insights from amphioxus into the evolution of vertebrate cartilage. PLoS One (2007) 1.16
Human ESC-derived neural crest model reveals a key role for SOX2 in sensory neurogenesis. Cell Stem Cell (2011) 1.16
Evolution of the neural crest viewed from a gene regulatory perspective. Genesis (2008) 1.16
MyMiner: a web application for computer-assisted biocuration and text annotation. Bioinformatics (2012) 1.16
Lens-derived Semaphorin3A regulates sensory innervation of the cornea. Dev Biol (2007) 1.15
N-cadherin acts in concert with Slit1-Robo2 signaling in regulating aggregation of placode-derived cranial sensory neurons. Development (2009) 1.14
Muscle stem cells. Curr Opin Cell Biol (2009) 1.14
Noelins modulate the timing of neuronal differentiation during development. Dev Biol (2005) 1.11
Excess FoxG1 causes overgrowth of the neural tube. J Neurobiol (2003) 1.10
Evidence for the prepattern/cooption model of vertebrate jaw evolution. Proc Natl Acad Sci U S A (2010) 1.07
Neural crest inducing signals. Adv Exp Med Biol (2006) 1.07
beta-Catenin-dependent Wnt signalling controls the epithelial organisation of somites through the activation of paraxis. Development (2005) 1.07
Intrinsic signals regulate the initial steps of myogenesis in vertebrates. Development (2003) 1.05
Early acquisition of neural crest competence during hESCs neuralization. PLoS One (2010) 1.05
What is bad in cancer is good in the embryo: importance of EMT in neural crest development. Semin Cell Dev Biol (2012) 1.05
Comprehensive spatiotemporal analysis of early chick neural crest network genes. Dev Dyn (2009) 1.04
Fate map and morphogenesis of presumptive neural crest and dorsal neural tube. Dev Biol (2009) 1.04
Corneal keratocytes retain neural crest progenitor cell properties. Dev Biol (2005) 1.04
Dynamic alterations in gene expression after Wnt-mediated induction of avian neural crest. Mol Biol Cell (2005) 1.03
Review: the role of neural crest cells in the endocrine system. Endocr Pathol (2009) 1.01
Essential role for PDGF signaling in ophthalmic trigeminal placode induction. Development (2008) 1.00
Discovery of transcription factors and other candidate regulators of neural crest development. Dev Dyn (2008) 1.00
Molecular and tissue interactions governing induction of cranial ectodermal placodes. Dev Biol (2009) 1.00
To proliferate or to die: role of Id3 in cell cycle progression and survival of neural crest progenitors. Genes Dev (2005) 0.99
Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice. Dev Biol (2002) 0.98
Central role of gene cooption in neural crest evolution. J Exp Zool B Mol Dev Evol (2005) 0.98
Insights from a sea lamprey into the evolution of neural crest gene regulatory network. Biol Bull (2008) 0.98
Developmental origins and evolution of jaws: new interpretation of "maxillary" and "mandibular". Dev Biol (2004) 0.97
Abnormalities in neural crest cell migration in laminin alpha5 mutant mice. Dev Biol (2005) 0.97
Semaphorin3A/neuropilin-1 signaling acts as a molecular switch regulating neural crest migration during cornea development. Dev Biol (2009) 0.96
The sea lamprey Petromyzon marinus: a model for evolutionary and developmental biology. Cold Spring Harb Protoc (2009) 0.95
The amphioxus SoxB family: implications for the evolution of vertebrate placodes. Int J Biol Sci (2007) 0.95
Myosin-X is critical for migratory ability of Xenopus cranial neural crest cells. Dev Biol (2009) 0.94
Conservation of Pax gene expression in ectodermal placodes of the lamprey. Gene (2002) 0.94
Id expression in amphioxus and lamprey highlights the role of gene cooption during neural crest evolution. Dev Biol (2003) 0.93
Competence, specification and commitment to an olfactory placode fate. Development (2008) 0.92
The timing of emergence of muscle progenitors is controlled by an FGF/ERK/SNAIL1 pathway. Dev Biol (2009) 0.92
Neural expression of mouse Noelin-1/2 and comparison with other vertebrates. Mech Dev (2002) 0.91
Expression of sympathetic nervous system genes in Lamprey suggests their recruitment for specification of a new vertebrate feature. PLoS One (2011) 0.90
Precocious terminal differentiation of premigratory limb muscle precursor cells requires positive signalling. Dev Dyn (2004) 0.90
Molecular mechanisms of neural crest induction. Birth Defects Res C Embryo Today (2004) 0.90
Graded potential of neural crest to form cornea, sensory neurons and cartilage along the rostrocaudal axis. Development (2004) 0.89
Hierarchy of regulatory events in sensory placode development. Curr Opin Genet Dev (2004) 0.89
Muscle stem cells and model systems for their investigation. Dev Dyn (2007) 0.89
Birth of ophthalmic trigeminal neurons initiates early in the placodal ectoderm. J Comp Neurol (2009) 0.88
EWS-FLI1 causes neuroepithelial defects and abrogates emigration of neural crest stem cells. Stem Cells (2008) 0.87
Pax3-expressing trigeminal placode cells can localize to trunk neural crest sites but are committed to a cutaneous sensory neuron fate. Dev Biol (2002) 0.87
Differential mesodermal expression of two amphioxus MyoD family members (AmphiMRF1 and AmphiMRF2). Gene Expr Patterns (2003) 0.87
Culturing lamprey embryos. Cold Spring Harb Protoc (2009) 0.86
Conservation and divergence of BMP2/4 genes in the lamprey: expression and phylogenetic analysis suggest a single ancestral vertebrate gene. Evol Dev (2004) 0.86
Evolutionary conservation of cell migration genes: from nematode neurons to vertebrate neural crest. Genes Dev (2007) 0.86
COMPARE, a multi-organism system for cross-species data comparison and transfer of information. Bioinformatics (2007) 0.85
Combined intrinsic and extrinsic influences pattern cranial neural crest migration and pharyngeal arch morphogenesis in axolotl. Dev Biol (2004) 0.84
Both neural crest and placode contribute to the ciliary ganglion and oculomotor nerve. Dev Biol (2003) 0.84