Published in Mol Cell Biochem on August 06, 2002
Pulmonary oxidative stress, inflammation and cancer: respirable particulate matter, fibrous dusts and ozone as major causes of lung carcinogenesis through reactive oxygen species mechanisms. Int J Environ Res Public Health (2013) 1.26
Antioxidant responses and cellular adjustments to oxidative stress. Redox Biol (2015) 1.15
SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB. J Cell Biol (2007) 1.11
Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell cycle checkpoint pathway. Chem Res Toxicol (2010) 1.02
PDCD4 gene silencing in gliomas is associated with 5'CpG island methylation and unfavourable prognosis. J Cell Mol Med (2009) 1.01
Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells. Toxicol Appl Pharmacol (2011) 1.01
Antioxidants tiron and N-acetyl-L-cysteine differentially mediate apoptosis in melanoma cells via a reactive oxygen species-independent NF-kappaB pathway. Free Radic Biol Med (2007) 0.97
ΔNp63 targets cytoglobin to inhibit oxidative stress-induced apoptosis in keratinocytes and lung cancer. Oncogene (2015) 0.95
Human papillomavirus type 16 E6* induces oxidative stress and DNA damage. J Virol (2014) 0.93
Cutaneous responses to environmental stressors. Ann N Y Acad Sci (2012) 0.91
Butein, a tetrahydroxychalcone, suppresses pro-inflammatory responses in HaCaT keratinocytes. BMB Rep (2015) 0.86
Caffeine Intake, Coffee Consumption, and Risk of Cutaneous Malignant Melanoma. Epidemiology (2015) 0.85
Different signaling mechanisms regulating IL-6 expression by LPS between gingival fibroblasts and mononuclear cells: seeking the common target. Clin Immunol (2012) 0.81
EGF activates PI3K-Akt and NF-kappaB via distinct pathways in salivary epithelial cells in Sjögren's syndrome. Rheumatol Int (2007) 0.81
Modulation of keratinocyte expression of antioxidants by 4-hydroxynonenal, a lipid peroxidation end product. Toxicol Appl Pharmacol (2014) 0.79
Reserpine Inhibit the JB6 P+ Cell Transformation Through Epigenetic Reactivation of Nrf2-Mediated Anti-oxidative Stress Pathway. AAPS J (2016) 0.78
Prevention of skin carcinogenesis by the β-blocker carvedilol. Cancer Prev Res (Phila) (2014) 0.77
Sesquiterpene lactones isolated from indigenous Middle Eastern plants inhibit tumor promoter-induced transformation of JB6 cells. BMC Complement Altern Med (2012) 0.76
Common and distinct mechanisms of different redox-active carcinogens involved in the transformation of mouse JB6P+ cells. Mol Carcinog (2008) 0.76
Electrolyzed Reduced Water Supplemented with Platinum Nanoparticles Suppresses Promotion of Two-stage Cell Transformation. Cytotechnology (2005) 0.76
Phenolic fraction of tobacco smoke condensate potentiates benzo[a]pyerene diol epoxide-induced cell transformation: role of protein kinase C. Mutat Res (2009) 0.76
Transcriptional regulation of heterogeneous nuclear ribonucleoprotein K gene expression. Biochimie (2014) 0.75
Overproduction of reactive oxygen species - obligatory or not for induction of apoptosis by anticancer drugs. Chin J Cancer Res (2016) 0.75
Inhibition of Neoplastic Transformation and Chemically-Induced Skin Hyperplasia in Mice by Traditional Chinese Medicinal Formula Si-Wu-Tang. Nutrients (2017) 0.75
Epigenetic modifications of triterpenoid ursolic acid in activating Nrf2 and blocking cellular transformation of mouse epidermal cells. J Nutr Biochem (2015) 0.75
Taxifolin Activates the Nrf2 Anti-Oxidative Stress Pathway in Mouse Skin Epidermal JB6 P+ Cells through Epigenetic Modifications. Int J Mol Sci (2017) 0.75
Mechanism of N-acetyl-cysteine inhibition on the cytotoxicity induced by titanium dioxide nanoparticles in JB6 cells transfected with activator protein-1. Exp Ther Med (2017) 0.75
S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science (2006) 5.94
The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. Mol Cell Biol (2003) 3.90
A novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A. Mol Cell Biol (2004) 2.38
Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis. Cancer Res (2005) 2.30
Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion. Mol Cell Biol (2006) 2.02
p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase. Cancer Res (2005) 1.88
Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation. Oncogene (2003) 1.87
Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion. Cancer Res (2008) 1.78
Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity. Mol Cancer Ther (2004) 1.60
Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse model. Mol Cancer Res (2003) 1.51
Structural basis for inhibition of translation by the tumor suppressor Pdcd4. Mol Cell Biol (2006) 1.49
Insufficient p65 phosphorylation at S536 specifically contributes to the lack of NF-kappaB activation and transformation in resistant JB6 cells. Carcinogenesis (2004) 1.46
Mutational analysis of the DEAD-box RNA helicase eIF4AII characterizes its interaction with transformation suppressor Pdcd4 and eIF4GI. RNA (2005) 1.40
Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo. Neuro Oncol (2011) 1.38
Fra-1 a target for cancer prevention or intervention. Gene (2006) 1.35
Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently. Mol Cell Biol (2002) 1.26
Promising molecular targets for cancer prevention: AP-1, NF-kappa B and Pdcd4. Trends Mol Med (2003) 1.21
AP-1 a target for cancer prevention. Curr Cancer Drug Targets (2007) 1.21
Consumption of a legume-enriched, low-glycemic index diet is associated with biomarkers of insulin resistance and inflammation among men at risk for colorectal cancer. J Nutr (2009) 1.19
Elevated inorganic phosphate stimulates Akt-ERK1/2-Mnk1 signaling in human lung cells. Am J Respir Cell Mol Biol (2006) 1.14
Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress. Biochem Biophys Res Commun (2005) 1.13
Histone deacetylase inhibition down-regulates cyclin D1 transcription by inhibiting nuclear factor-kappaB/p65 DNA binding. Mol Cancer Res (2005) 1.13
Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation. Oncogene (2004) 1.11
Sulfiredoxin-Peroxiredoxin IV axis promotes human lung cancer progression through modulation of specific phosphokinase signaling. Proc Natl Acad Sci U S A (2011) 1.11
Monitoring of tumor promotion and progression in a mouse model of inflammation-induced colon cancer with magnetic resonance colonography. Neoplasia (2009) 1.11
Aerosol delivery of urocanic acid-modified chitosan/programmed cell death 4 complex regulated apoptosis, cell cycle, and angiogenesis in lungs of K-ras null mice. Mol Cancer Ther (2006) 1.09
Sulfiredoxin is an AP-1 target gene that is required for transformation and shows elevated expression in human skin malignancies. Proc Natl Acad Sci U S A (2008) 1.08
A high legume low glycemic index diet improves serum lipid profiles in men. Lipids (2010) 1.08
Fluorescence endoscopic detection of murine colitis-associated colon cancer by topically applied enzymatically rapid-activatable probe. Gut (2012) 1.07
Elevated phosphate activates N-ras and promotes cell transformation and skin tumorigenesis. Cancer Prev Res (Phila) (2010) 1.07
AP-1, NF-kappa-B, and ERK activation thresholds for promotion of neoplastic transformation in the mouse epidermal JB6 model. Environ Health Perspect (2002) 1.07
Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities. J Med Chem (2008) 1.04
STAT3 activation is required for interleukin-6 induced transformation in tumor-promotion sensitive mouse skin epithelial cells. Oncogene (2002) 1.03
A high-throughput cell-based assay to identify specific inhibitors of transcription factor AP-1. J Biomol Screen (2006) 1.02
Inflammation-induced loss of Pdcd4 is mediated by phosphorylation-dependent degradation. Carcinogenesis (2011) 1.01
Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600. J Nat Prod (2011) 1.00
A selective small-molecule nuclear factor-kappaB inhibitor from a high-throughput cell-based assay for "activator protein-1 hits". Mol Cancer Ther (2009) 1.00
The AP-1 transcription factor regulates postnatal mammary gland development. Dev Biol (2006) 0.99
Programmed cell death 4 inhibits breast cancer cell invasion by increasing tissue inhibitor of metalloproteinases-2 expression. Breast Cancer Res Treat (2008) 0.99
JNK/AP-1 pathway is involved in tumor necrosis factor-alpha induced expression of vascular endothelial growth factor in MCF7 cells. Biomed Pharmacother (2009) 0.98
An integrated understanding of the physiological response to elevated extracellular phosphate. J Cell Physiol (2013) 0.98
Development of a high-throughput cell-based reporter assay to identify stabilizers of tumor suppressor Pdcd4. J Biomol Screen (2009) 0.98
Noninvasive detection of candidate molecular biomarkers in subjects with a history of insulin resistance and colorectal adenomas. Cancer Prev Res (Phila) (2009) 0.96
Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis. Cancer Res (2007) 0.96
Bioactive food components, inflammatory targets, and cancer prevention. Cancer Prev Res (Phila) (2009) 0.96
Targeting the activator protein 1 transcription factor for the prevention of estrogen receptor-negative mammary tumors. Cancer Prev Res (Phila) (2008) 0.96
Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-catenin. Cancer Res (2013) 0.95
Erioflorin stabilizes the tumor suppressor Pdcd4 by inhibiting its interaction with the E3-ligase β-TrCP1. PLoS One (2012) 0.95
The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation. Toxicol Appl Pharmacol (2008) 0.95
Aerosol delivery of glucosylated polyethylenimine/phosphatase and tensin homologue deleted on chromosome 10 complex suppresses Akt downstream pathways in the lung of K-ras null mice. Cancer Res (2004) 0.95
Suppression of p65 phosphorylation coincides with inhibition of IkappaBalpha polyubiquitination and degradation. Mol Carcinog (2005) 0.95
Cryptocaryols A-H, α-pyrone-containing 1,3-polyols from Cryptocarya sp. implicated in stabilizing the tumor suppressor Pdcd4. J Nat Prod (2011) 0.94
Downregulation of programmed cell death 4 by inflammatory conditions contributes to the generation of the tumor promoting microenvironment. Mol Carcinog (2010) 0.94
Interleukin-6 as a potential indicator for prevention of high-risk adenoma recurrence by dietary flavonols in the polyp prevention trial. Cancer Prev Res (Phila) (2010) 0.93
Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in ob/ob mice. Cancer Prev Res (Phila) (2009) 0.93
Have tumor suppressor PDCD4 and its counteragent oncogenic miR-21 gone rogue? Mol Interv (2010) 0.93
STAT2 contributes to promotion of colorectal and skin carcinogenesis. Cancer Prev Res (Phila) (2010) 0.92
The untapped potential of genetically engineered mouse models in chemoprevention research: opportunities and challenges. Cancer Prev Res (Phila) (2008) 0.92
Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob mice. Nutr Cancer (2008) 0.91
Protection against human papillomavirus type 16-E7 oncogene-induced tumorigenesis by in vivo expression of dominant-negative c-jun. Mol Carcinog (2002) 0.91
Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition. J Nat Prod (2009) 0.90
Role of 3'UTRs in the translation of mRNAs regulated by oncogenic eIF4E--a computational inference. PLoS One (2009) 0.88
Cancer stem cells: potential target for bioactive food components. J Nutr Biochem (2012) 0.86
Nitric oxide does not mediate but inhibits transformation and tumor phenotype. Mol Cancer Ther (2003) 0.86
Microwave-based reaction screening: tandem retro-Diels-Alder/Diels-Alder cycloadditions of o-quinol dimers. J Org Chem (2011) 0.84
AP-1 transrepressing retinoic acid does not deplete coactivators or AP-1 monomers but may target specific Jun or Fos containing dimers. Oncogene (2002) 0.83
Linoleic acid metabolite suppresses skin inflammation and tumor promotion in mice: possible roles of programmed cell death 4 induction. Carcinogenesis (2009) 0.83
Programmed cell death 4 (PDCD4): a novel player in ethanol-mediated suppression of protein translation in primary cortical neurons and developing cerebral cortex. Alcohol Clin Exp Res (2012) 0.82
A dominant-negative c-jun mutant inhibits lung carcinogenesis in mice. Cancer Prev Res (Phila) (2010) 0.82
Targeting of Noncanonical Wnt5a Signaling by AP-1 Blocker Dominant-Negative Jun When It Inhibits Skin Carcinogenesis. Genes Cancer (2012) 0.82
Plasma cytokines as potential response indicators to dietary freeze-dried black raspberries in colorectal cancer patients. Nutr Cancer (2012) 0.80
A paracrine signal mediates the cell transformation response to low dose gamma radiation in JB6 cells. Mol Carcinog (2005) 0.80
Identification and monitoring of metabolite markers of dry bean consumption in parallel human and mouse studies. Mol Nutr Food Res (2015) 0.78
Inhibitors of the oncogenic transcription factor AP-1 from Podocarpus latifolius. J Nat Prod (2011) 0.78
Loss of sulfiredoxin renders mice resistant to azoxymethane/dextran sulfate sodium-induced colon carcinogenesis. Carcinogenesis (2013) 0.78
Tumor promoter-induced sulfiredoxin is required for mouse skin tumorigenesis. Carcinogenesis (2014) 0.78
Cryptotanshinone, a Stat3 inhibitor, suppresses colorectal cancer proliferation and growth in vitro. Mol Cell Biochem (2015) 0.77
Grassypeptolides F and G, cyanobacterial peptides from Lyngbya majuscula. J Nat Prod (2011) 0.77
Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii. Bioorg Med Chem Lett (2011) 0.75
Do interleukin polymorphisms play a role in the prevention of colorectal adenoma recurrence by dietary flavonols? Eur J Cancer Prev (2011) 0.75
Activation of NF-kappaB is required for PDGF-B chain to transform NIH3T3 cells. Exp Cell Res (2002) 0.75
Molecular targets for cancer prevention: a meeting review of the third American Cancer Society-Schilling Research Conference. Cancer Epidemiol Biomarkers Prev (2002) 0.75