Published in Am J Physiol Endocrinol Metab on September 01, 2002
Thyroid hormone mimetics: potential applications in atherosclerosis, obesity and type 2 diabetes. Nat Rev Drug Discov (2009) 1.92
The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis. Mol Endocrinol (2011) 1.10
Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life. Proc Natl Acad Sci U S A (2004) 1.10
Secondary coronary artery vasospasm promotes cardiomyopathy progression. Am J Pathol (2004) 0.91
Resistance to diet-induced obesity in mice globally overexpressing OGH/GPB5. Proc Natl Acad Sci U S A (2005) 0.85
New avenues for regulation of lipid metabolism by thyroid hormones and analogs. Front Physiol (2014) 0.80
The thyroid receptor modulator KB3495 reduces atherosclerosis independently of total cholesterol in the circulation in ApoE deficient mice. PLoS One (2013) 0.77
3D echocardiography: a review of the current status and future directions. J Am Soc Echocardiogr (2007) 2.12
Case records of the Massachusetts General Hospital. Case 26-2011. A 7-year-old boy with a complex cyst in the kidney. N Engl J Med (2011) 2.06
Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice. J Clin Invest (2002) 1.76
Thyroid hormone receptors: lessons from knockout and knock-in mutant mice. Trends Endocrinol Metab (2003) 1.69
Role of miR-34c microRNA in the late steps of spermatogenesis. RNA (2010) 1.60
The Oct4 homologue PouV and Nanog regulate pluripotency in chicken embryonic stem cells. Development (2007) 1.42
Chondrocytes play a major role in the stimulation of bone growth by thyroid hormone. Endocrinology (2014) 1.41
Which method should be the reference method to evaluate the severity of rheumatic mitral stenosis? Gorlin's method versus 3D-echo. Eur J Echocardiogr (2006) 1.41
Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene. Mol Endocrinol (2002) 1.36
Thyroid hormone excess rather than thyrotropin deficiency induces osteoporosis in hyperthyroidism. Mol Endocrinol (2007) 1.33
25-Hydroxyvitamin D and parathyroid hormone are not associated with carotid intima-media thickness or plaque in the multi-ethnic study of atherosclerosis. Arterioscler Thromb Vasc Biol (2013) 1.33
A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism. Mol Endocrinol (2007) 1.27
Targeting BRAFV600E with PLX4720 displays potent antimigratory and anti-invasive activity in preclinical models of human thyroid cancer. Oncologist (2011) 1.27
A mechanism regulating the onset of Sox2 expression in the embryonic neural plate. PLoS Biol (2008) 1.23
The overexpression of the putative gut stem cell marker Musashi-1 induces tumorigenesis through Wnt and Notch activation. J Cell Sci (2010) 1.21
Poly(ADP-ribose) polymerase-1-deficient mice are protected from angiotensin II-induced cardiac hypertrophy. Am J Physiol Heart Circ Physiol (2006) 1.20
Molecular analysis of the protease-resistant prion protein in scrapie and bovine spongiform encephalopathy transmitted to ovine transgenic and wild-type mice. J Virol (2004) 1.20
SCF(β-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2. J Exp Med (2012) 1.18
Thyroid hormone receptor alpha1 directly controls transcription of the beta-catenin gene in intestinal epithelial cells. Mol Cell Biol (2006) 1.14
p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer. Proc Natl Acad Sci U S A (2014) 1.14
International Union of Pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: thyroid hormone receptors. Pharmacol Rev (2006) 1.14
Two uniquely arranged thyroid hormone response elements in the far upstream 5' flanking region confer direct thyroid hormone regulation to the murine cholesterol 7alpha hydroxylase gene. Nucleic Acids Res (2006) 1.13
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Res (2010) 1.13
Late intervention with anti-BRAF(V600E) therapy induces tumor regression in an orthotopic mouse model of human anaplastic thyroid cancer. Endocrinology (2011) 1.13
Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice. EMBO Rep (2003) 1.12
Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life. Proc Natl Acad Sci U S A (2004) 1.10
Klebsiella pneumoniae necrotizing fasciitis and septic arthritis: an appearance in the Western hemisphere. Surg Infect (Larchmt) (2007) 1.10
Drilled hole defects in mouse femur as models of intramembranous cortical and cancellous bone regeneration. Calcif Tissue Int (2009) 1.10
The frizzled-related sFRP2 gene is a target of thyroid hormone receptor alpha1 and activates beta-catenin signaling in mouse intestine. J Biol Chem (2008) 1.09
Thyroid hormones and the control of cell proliferation or cell differentiation: paradox or duality? Mol Cell Endocrinol (2009) 1.09
Mice lacking the thyroid hormone receptor-alpha gene spend more energy in thermogenesis, burn more fat, and are less sensitive to high-fat diet-induced obesity. Endocrinology (2008) 1.08
Angiogenin-stimulated rRNA transcription is essential for initiation and survival of AKT-induced prostate intraepithelial neoplasia. Mol Cancer Res (2009) 1.08
Renal cell carcinoma in tuberous sclerosis complex. Am J Surg Pathol (2014) 1.08
Detection of novel actionable genetic changes in salivary duct carcinoma helps direct patient treatment. Clin Cancer Res (2012) 1.06
Thyroid hormones signaling is getting more complex: STORMs are coming. Mol Endocrinol (2006) 1.02
VIP and PACAP induce selective neuronal differentiation of mouse embryonic stem cells. Eur J Neurosci (2004) 0.99
BRAF V600E status adds incremental value to current risk classification systems in predicting papillary thyroid carcinoma recurrence. Surgery (2012) 0.99
Temperature homeostasis in transgenic mice lacking thyroid hormone receptor-alpha gene products. Endocrinology (2005) 0.99
Thyroid hormone activates fibroblast growth factor receptor-1 in bone. Mol Endocrinol (2003) 0.97
Early variations of host thyroxine and interleukin-7 favor Schistosoma mansoni development. J Parasitol (2002) 0.97
Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. J Clin Endocrinol Metab (2014) 0.97
Thyroid hormones regulate fibroblast growth factor receptor signaling during chondrogenesis. Endocrinology (2005) 0.96
Specificity of thyroid hormone receptor subtype and steroid receptor coactivator-1 on thyroid hormone action. Am J Physiol Endocrinol Metab (2002) 0.96
Neamine inhibits prostate cancer growth by suppressing angiogenin-mediated rRNA transcription. Clin Cancer Res (2009) 0.96
TM4SF1, a novel primary androgen receptor target gene over-expressed in human prostate cancer and involved in cell migration. Prostate (2011) 0.95
Molecular mechanisms of thyroid hormone effects on bone growth and function. Mol Genet Metab (2002) 0.95
Ectopic expression of Cvh (Chicken Vasa homologue) mediates the reprogramming of chicken embryonic stem cells to a germ cell fate. Dev Biol (2009) 0.95
Poorly differentiated thyroid carcinoma: a cytologic-histologic review. Adv Anat Pathol (2009) 0.94
Lateral dermoid cyst of the floor of mouth: unusual radiologic and pathologic findings. Auris Nasus Larynx (2011) 0.94
Bone sialoprotein, but not osteopontin, deficiency impairs the mineralization of regenerating bone during cortical defect healing. Bone (2009) 0.93
Epithelioid angiomyolipoma of the kidney: pathological features and clinical outcome in a series of consecutively resected tumors. Mod Pathol (2013) 0.93
A point mutation in the activation function 2 domain of thyroid hormone receptor alpha1 expressed after CRE-mediated recombination partially recapitulates hypothyroidism. Mol Endocrinol (2007) 0.93
Diagnostic characteristics of sinonasal organizing hematomas: avoiding misdiagnosis. Int Forum Allergy Rhinol (2013) 0.93
Thyroid hormone receptor beta (TRbeta) and liver X receptor (LXR) regulate carbohydrate-response element-binding protein (ChREBP) expression in a tissue-selective manner. J Biol Chem (2010) 0.93
Regulation of expression of thyroid hormone receptor isoforms and coactivators in liver and heart by thyroid hormone. Mol Cell Endocrinol (2003) 0.92
Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors. Proc Natl Acad Sci U S A (2002) 0.92
Hobnail variant of papillary thyroid carcinoma: an institutional case series and molecular profile. Thyroid (2014) 0.91
Evaluation of cardiovascular flow characteristics in the 129Sv mouse fetus using color-Doppler-guided spectral Doppler ultrasound. Vet Radiol Ultrasound (2004) 0.91
A patient with ectopic cortisol production derived from malignant testicular masses. Nat Clin Pract Endocrinol Metab (2008) 0.90
Peripheral circulation of the prion infectious agent in transgenic mice expressing the ovine prion protein gene in neurons only. J Infect Dis (2007) 0.89
Distinct modulatory roles for thyroid hormone receptors TRalpha and TRbeta in SREBP1-activated ABCD2 expression. Eur J Cell Biol (2008) 0.89
The role of imaging in chronic degenerative mitral regurgitation. JACC Cardiovasc Imaging (2008) 0.89
The effects of ramipril in individuals at risk for Alzheimer's disease: results of a pilot clinical trial. J Alzheimers Dis (2012) 0.89
Interinstitutional whole slide imaging teleconsultation service development: assessment using internal training and clinical consultation cases. Arch Pathol Lab Med (2014) 0.88
Behavioral inhibition and impaired spatial learning and memory in hypothyroid mice lacking thyroid hormone receptor alpha. Behav Brain Res (2006) 0.88
TRbeta is the critical thyroid hormone receptor isoform in T3-induced proliferation of hepatocytes and pancreatic acinar cells. J Hepatol (2010) 0.88
Identification of oncogenic mutations and gene fusions in the follicular variant of papillary thyroid carcinoma. J Clin Endocrinol Metab (2014) 0.88
Both thyroid hormone receptor (TR)beta 1 and TR beta 2 isoforms contribute to the regulation of hypothalamic thyrotropin-releasing hormone. Endocrinology (2004) 0.88
Deafness in TRbeta mutants is caused by malformation of the tectorial membrane. J Neurosci (2009) 0.88
Thyroid hormone receptor β mediates thyroid hormone effects on bone remodeling and bone mass. J Bone Miner Res (2011) 0.87
The lipoprotein lipase inhibitor ANGPTL3 is negatively regulated by thyroid hormone. J Biol Chem (2006) 0.87
Cooperation between the thyroid hormone receptor TRalpha1 and the WNT pathway in the induction of intestinal tumorigenesis. Gastroenterology (2010) 0.87
FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma. Endocr Relat Cancer (2012) 0.87
Intraoperative diagnosis of a functional paraganglioma presenting as a gastrointestinal stromal cell tumor (GIST). J Clin Anesth (2009) 0.87
Absence of ERRalpha in female mice confers resistance to bone loss induced by age or estrogen-deficiency. PLoS One (2009) 0.87
Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum. Dev Biol (2003) 0.86
Thyroid hormone receptor {alpha} modulates lipopolysaccharide-induced changes in peripheral thyroid hormone metabolism. Endocrinology (2010) 0.86
Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency. Endocrinology (2002) 0.86
Treatment outcomes and prognostic factors, including human papillomavirus, for sinonasal undifferentiated carcinoma: a retrospective review. Head Neck (2014) 0.86
Tissue responses to thyroid hormone in a kindred with resistance to thyroid hormone harboring a commonly occurring mutation in the thyroid hormone receptor beta gene (P453T). J Lab Clin Med (2005) 0.86
Role of the epigenetic regulator HP1γ in the control of embryonic stem cell properties. PLoS One (2010) 0.85
Direct cooperation between androgen receptor and E2F1 reveals a common regulation mechanism for androgen-responsive genes in prostate cells. Mol Endocrinol (2012) 0.85
Thyroid hormone T3 acting through the thyroid hormone alpha receptor is necessary for implementation of erythropoiesis in the neonatal spleen environment in the mouse. Development (2005) 0.84
The endogenous retrovirus ENS-1 provides active binding sites for transcription factors in embryonic stem cells that specify extra embryonic tissue. Retrovirology (2012) 0.84
Thyroid hormone receptor-specific interactions with steroid receptor coactivator-1 in the pituitary. Mol Endocrinol (2003) 0.84
The targeted inactivation of TRβ gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production. Endocrinology (2013) 0.84
Layer-by-layer tissue microfabrication supports cell proliferation in vitro and in vivo. Tissue Eng Part C Methods (2011) 0.83
Myopericytoma tumor of the glans penis. Can J Urol (2015) 0.82
Thyroid hormone regulates hepatic triglyceride mobilization and apolipoprotein B messenger ribonucleic Acid editing in a murine model of congenital hypothyroidism. Endocrinology (2003) 0.82