Published in Cancer Biol Ther on August 12, 2002
A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein. Genes Dev (2003) 2.09
Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a. Mol Cell Biol (2003) 1.38
Functional genomics in radiation biology: a gateway to cellular systems-level studies. Radiat Environ Biophys (2007) 1.18
Transcriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptation. Nucleic Acids Res (2013) 1.03
DNA repair and cell cycle biomarkers of radiation exposure and inflammation stress in human blood. PLoS One (2012) 0.97
The role of XPC: implications in cancer and oxidative DNA damage. Mutat Res (2011) 0.94
Functional regulation of the DNA damage-recognition factor DDB2 by ubiquitination and interaction with xeroderma pigmentosum group C protein. Nucleic Acids Res (2015) 0.87
Posttranscriptional regulation of gene expression-adding another layer of complexity to the DNA damage response. Front Genet (2012) 0.87
Construction and purification of site-specifically modified DNA templates for transcription assays. Nucleic Acids Res (2003) 0.85
DNA repair genes: alternative transcription and gene expression at the exon level in response to the DNA damaging agent, ionizing radiation. PLoS One (2012) 0.82
Involvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ). Subcell Biochem (2014) 0.80
p53 haploinsufficiency profoundly accelerates the onset of tongue tumors in mice lacking the xeroderma pigmentosum group A gene. Am J Pathol (2003) 0.80
Identification of a Functional In Vivo p53 Response Element in the Coding Sequence of the Xeroderma Pigmentosum Group C Gene. Genes Cancer (2012) 0.79
The relevance of the vitamin D endocrine system (VDES) for tumorigenesis, prevention, and treatment of non-melanoma skin cancer (NMSC): Present concepts and future perspectives. Dermatoendocrinol (2013) 0.78
Xeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulation. Cell Mol Life Sci (2015) 0.77
Global genomic repair and p53 in a dance after DNA damage. Cancer Biol Ther (2002) 0.77
Signal oscillation is another reason for variability in microarray-based gene expression quantification. PLoS One (2013) 0.76
Pathways to chromothripsis. Cell Cycle (2015) 0.75
Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis. Carcinogenesis (2016) 0.75
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell (1992) 19.87
An information-intensive approach to the molecular pharmacology of cancer. Science (1997) 11.43
p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes. Mol Cell Biol (2000) 6.23
Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. Science (1994) 6.11
Repair of gamma-ray-induced DNA base damage in xeroderma pigmentosum cells. Radiat Res (1986) 5.08
Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res (1997) 4.34
The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth. Mol Cell Biol (1994) 4.15
Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO J (1999) 3.46
Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status. Mol Cell Biol (1994) 3.30
Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase. Nature (2001) 3.25
Genomic instability in Gadd45a-deficient mice. Nat Genet (1999) 3.01
GADD45 induction of a G2/M cell cycle checkpoint. Proc Natl Acad Sci U S A (1999) 2.80
Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol Cell Biol (1993) 2.77
An informatics approach identifying markers of chemosensitivity in human cancer cell lines. Cancer Res (2000) 2.47
The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia. Cancer Res (1994) 2.41
Induction of B2 RNA polymerase III transcription by heat shock: enrichment for heat shock induced sequences in rodent cells by hybridization subtraction. Nucleic Acids Res (1986) 2.31
Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses. Oncogene (1999) 2.29
Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45. Oncogene (1999) 2.12
Identification of potential mRNA biomarkers in peripheral blood lymphocytes for human exposure to ionizing radiation. Radiat Res (2000) 2.11
The management of ocular herpes. Trans Ophthalmol Soc U K (1967) 2.08
Propofol 2% in critically ill patients: effect on lipids. Crit Care Med (1997) 2.07
p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha. Cancer Res (1998) 2.02
Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Res (1995) 2.00
Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage. Oncogene (1995) 2.00
Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin. Mol Cell Biol (1999) 1.97
Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix. Clin Cancer Res (2001) 1.95
p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents. Cancer Res (1994) 1.94
Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis. Oncogene (1994) 1.88
Myc represses the growth arrest gene gadd45. Oncogene (1997) 1.86
Mammalian GADD34, an apoptosis- and DNA damage-inducible gene. J Biol Chem (1997) 1.85
T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells. Proc Natl Acad Sci U S A (1984) 1.77
Response to adversity: molecular control of gene activation following genotoxic stress. New Biol (1991) 1.72
Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress. Oncogene (1998) 1.71
Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C. Mol Cell Biol (1991) 1.69
Induction of gene expression as a monitor of exposure to ionizing radiation. Radiat Res (2001) 1.69
Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins. Mol Cell Biol (1999) 1.62
The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression. J Biol Chem (2000) 1.62
Death and dying: attitudes in a teaching hospital. Urology (1974) 1.59
Analysis of the mammalian gadd45 gene and its response to DNA damage. J Biol Chem (1993) 1.58
Isolation, characterization and chromosomal localization of the human GADD153 gene. Gene (1992) 1.55
Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway. Proc Natl Acad Sci U S A (1994) 1.53
Regulation of translation initiation following stress. Oncogene (1999) 1.51
The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21WAF1/CIP1. Oncogene (1996) 1.51
Decreased expression of heat shock protein 70 mRNA and protein after heat treatment in cells of aged rats. Proc Natl Acad Sci U S A (1990) 1.51
Evolution and organization of the fibrinogen locus on chromosome 4: gene duplication accompanied by transposition and inversion. Proc Natl Acad Sci U S A (1985) 1.49
Evolution and structure of the fibrinogen genes. Random insertion of introns or selective loss? J Mol Biol (1985) 1.47
DNA single-strand breaks during repair of UV damage in human fibroblasts and abnormalities of repair in xeroderma pigmentosum. Proc Natl Acad Sci U S A (1976) 1.42
Induction of fos RNA by DNA-damaging agents. Cancer Res (1989) 1.41
Induction of stress genes by low doses of gamma rays. Radiat Res (1999) 1.41
The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis. Oncogene (2006) 1.40
Effect of centralized intake on outcomes of substance abuse treatment. Psychiatr Serv (1996) 1.39
A phase II trial of the cyclin-dependent kinase inhibitor flavopiridol in patients with previously untreated stage IV non-small cell lung cancer. Clin Cancer Res (2001) 1.37
Death and decoy receptors and p53-mediated apoptosis. Leukemia (2000) 1.36
Aggressive angiomyxoma of pelvic parts exhibits oestrogen and progesterone receptor positivity. J Clin Pathol (2000) 1.36
Metallothionein gene expression and resistance to cisplatin in human ovarian cancer. Int J Cancer (1990) 1.35
Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding. Mol Cell Biol (1998) 1.35
Biological indicators for the identification of ionizing radiation exposure in humans. Expert Rev Mol Diagn (2001) 1.34
Recombination of parent and daughter strand DNA after UV-irradiation in mammalian cells. Nature (1983) 1.33
Role of p53 family members in apoptosis. J Cell Physiol (2000) 1.31
Low-ratio hybridization subtraction. Anal Biochem (1990) 1.31
Structure of the human gamma-fibrinogen gene. Alternate mRNA splicing near the 3' end of the gene produces gamma A and gamma B forms of gamma-fibrinogen. J Biol Chem (1984) 1.30
Cytoplasmic dynein contains a family of differentially expressed light chains. Biochemistry (1998) 1.29
Altered cell cycle control at the G(2)/M phases in aryl hydrocarbon receptor-null embryo fibroblast. Mol Pharmacol (2000) 1.28
Analyzing refractive changes after anterior segment surgery. J Cataract Refract Surg (2001) 1.28
Management of women with a cervical smear showing a mild degree of dyskaryosis: a review of policy. Cytopathology (1992) 1.27
Evidence for herpes simplex viral latency in the human cornea. Br J Ophthalmol (1991) 1.27
Genotoxic stress confers preferential and coordinate messenger RNA stability on the five gadd genes. Cancer Res (1994) 1.26
Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein. J Biol Chem (1997) 1.26
The p53-dependent gamma-ray response of GADD45. Cancer Res (1994) 1.25
p53-mediated protective responses to UV irradiation. Proc Natl Acad Sci U S A (1997) 1.24
Single-strand scission and repair of DNA in mammalian cells by bleomycin. Cancer Res (1976) 1.23
Antisense GADD45 expression results in decreased DNA repair and sensitizes cells to u.v.-irradiation or cisplatin. Oncogene (1996) 1.23
Isolation and characterization of the hamster gadd153 gene. Activation of promoter activity by agents that damage DNA. J Biol Chem (1990) 1.22
Pathology of posterior polymorphous degeneration of the cornea. Br J Ophthalmol (1967) 1.20
Activation of Gadd34 by diverse apoptotic signals and suppression of its growth inhibitory effects by apoptotic inhibitors. Int J Cancer (2001) 1.19
Genomic instability and the role of p53 mutations in cancer cells. Curr Opin Oncol (1995) 1.18
Oligomerization of human Gadd45a protein. J Biol Chem (2001) 1.18
Abrogation of p53 function affects gadd gene responses to DNA base-damaging agents and starvation. DNA Cell Biol (1996) 1.18
The involvement of aryl hydrocarbon receptor in the activation of transforming growth factor-beta and apoptosis. Mol Pharmacol (1998) 1.17
Topical Lomefloxacin versus Topical Chloramphenicol in the Treatment of Acute Bacterial Conjunctivitis. Clin Drug Investig (1998) 1.15
Estimation of relative mRNA content by filter hybridization to a polythymidylate probe. Biotechniques (1990) 1.14
Characterization of p21Cip1/Waf1 peptide domains required for cyclin E/Cdk2 and PCNA interaction. Oncogene (1996) 1.14
Pharmacokinetics of oral acyclovir (Zovirax) in the eye. Br J Ophthalmol (1984) 1.12
Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard. Oncogene (1997) 1.12
Formaldehyde damage to DNA and inhibition of DNA repair in human bronchial cells. Science (1983) 1.10
Dimethylbenzanthracene carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair and increased mutation frequency. Cancer Res (2001) 1.08
DNA crosslinking induced by x-rays and chemical agents. Biochim Biophys Acta (1977) 1.08
A randomised double-blind clinical trial of acyclovir (Zovirax) and adenine arabinoside in herpes simplex corneal ulceration. Br J Ophthalmol (1982) 1.07
Regulation of insulin-like growth factor II P3 promotor by p53: a potential mechanism for tumorigenesis. Cancer Res (1996) 1.07
p21(Waf1) is required for cellular senescence but not for cell cycle arrest induced by the HDAC inhibitor sodium butyrate. Cell Cycle (2010) 1.07
Transcriptome of channel catfish (Ictalurus punctatus): initial analysis of genes and expression profiles of the head kidney. Anim Genet (2001) 1.06
Symposium on certain forms of infective kerato-uveitis or uveitis. I. An approach to the problem, and the technique of anterior chamber tap. Trans Ophthalmol Soc U K (1969) 1.05
Direct interaction of Gadd45 with PCNA and evidence for competitive interaction of Gadd45 and p21Waf1/Cip1 with PCNA. Oncogene (1995) 1.04
Myc suppresses induction of the growth arrest genes gadd34, gadd45, and gadd153 by DNA-damaging agents. Oncogene (1998) 1.04
Enhancement of X ray induced DNA damage by pre-treatment with halogenated pyrimidine analogs. Int J Radiat Oncol Biol Phys (1987) 1.04
BRCA1 activation of the GADD45 promoter. Oncogene (2000) 1.03
Role of p21Waf1/Cip1/Sdi1 in cell death and DNA repair as studied using a tetracycline-inducible system in p53-deficient cells. Oncogene (1997) 1.03
Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1. Oncogene (1998) 1.03