Published in Circulation on August 20, 2002
Valve-Related Hemodynamics Mediate Human Bicuspid Aortopathy: Insights From Wall Shear Stress Mapping. J Am Coll Cardiol (2015) 3.51
Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy. Circulation (2013) 3.23
Aortopathy is prevalent in relatives of bicuspid aortic valve patients. J Am Coll Cardiol (2009) 2.00
Differential tensile strength and collagen composition in ascending aortic aneurysms by aortic valve phenotype. Ann Thorac Surg (2013) 1.71
Basal and oxidative stress-induced expression of metallothionein is decreased in ascending aortic aneurysms of bicuspid aortic valve patients. Circulation (2009) 1.67
Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves. J Clin Invest (2010) 1.51
Canadian Cardiovascular Society 2009 Consensus Conference on the management of adults with congenital heart disease: outflow tract obstruction, coarctation of the aorta, tetralogy of Fallot, Ebstein anomaly and Marfan's syndrome. Can J Cardiol (2010) 1.40
Quantification of hemodynamic wall shear stress in patients with bicuspid aortic valve using phase-contrast MRI. Ann Biomed Eng (2009) 1.37
Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation. Circ Res (2011) 1.28
Impact of bicuspid aortic valve on complications and death in infective endocarditis of native aortic valves. Tex Heart Inst J (2009) 1.20
Endocarditis with ruptured cerebral aneurysm caused by Cardiobacterium valvarum sp. nov. J Clin Microbiol (2004) 1.19
Influence of beta-blocker therapy on aortic blood flow in patients with bicuspid aortic valve. Int J Cardiovasc Imaging (2016) 1.08
Bicuspid aortic valve: identifying knowledge gaps and rising to the challenge from the International Bicuspid Aortic Valve Consortium (BAVCon). Circulation (2014) 1.06
Post-stenotic aortic dilatation. J Cardiothorac Surg (2006) 1.01
Bicuspid aortic valve disease: a comprehensive review. Cardiol Res Pract (2012) 1.01
Bicuspid aortic valve and coarctation: two villains part of a diffuse problem. Heart (2003) 0.99
Dilatation of the ascending aorta in bicuspid aortic valve disease: a magnetic resonance imaging study. Clin Res Cardiol (2008) 0.99
Coronary artery anomalies. Part I: Recent insights from molecular embryology. Z Kardiol (2004) 0.97
Histological and genetic studies in patients with bicuspid aortic valve and ascending aorta complications. Interact Cardiovasc Thorac Surg (2011) 0.96
Application of gene network analysis techniques identifies AXIN1/PDIA2 and endoglin haplotypes associated with bicuspid aortic valve. PLoS One (2010) 0.96
A roadmap to investigate the genetic basis of bicuspid aortic valve and its complications: insights from the International BAVCon (Bicuspid Aortic Valve Consortium). J Am Coll Cardiol (2014) 0.96
The long non-coding HOTAIR is modulated by cyclic stretch and WNT/β-CATENIN in human aortic valve cells and is a novel repressor of calcification genes. PLoS One (2014) 0.92
Proteomic alterations in heat shock protein 27 and identification of phosphoproteins in ascending aortic aneurysm associated with bicuspid and tricuspid aortic valve. J Mol Cell Cardiol (2007) 0.90
Biomechanical characterization of ascending aortic aneurysm with concomitant bicuspid aortic valve and bovine aortic arch. Acta Biomater (2013) 0.89
Characteristics of aortic valve dysfunction and ascending aorta dimensions according to bicuspid aortic valve morphology. Eur Radiol (2015) 0.89
Effect of Geometry on the Leaflet Stresses in Simulated Models of Congenital Bicuspid Aortic Valves. Cardiovasc Eng Technol (2011) 0.88
Antithrombotic medication for cardioembolic stroke prevention. Stroke Res Treat (2011) 0.87
Architectural trends in the human normal and bicuspid aortic valve leaflet and its relevance to valve disease. Ann Biomed Eng (2014) 0.87
Etiology of bicuspid aortic valve disease: Focus on hemodynamics. World J Cardiol (2014) 0.84
Genotype-phenotype correlation in patients with bicuspid aortic valve and aneurysm. J Thorac Cardiovasc Surg (2012) 0.84
Long-term results after treatment of the ascending aorta for bicuspid aortic valve patients. Surg Today (2015) 0.84
Predictive biomechanical analysis of ascending aortic aneurysm rupture potential. Acta Biomater (2013) 0.83
Role of Computational Simulations in Heart Valve Dynamics and Design of Valvular Prostheses. Cardiovasc Eng Technol (2010) 0.83
Aorta Measurements are Heritable and Influenced by Bicuspid Aortic Valve. Front Genet (2011) 0.83
Aortic valve sclerosis in mice deficient in endothelial nitric oxide synthase. Am J Physiol Heart Circ Physiol (2014) 0.83
Genetically alike Syrian hamsters display both bifoliate and trifoliate aortic valves. J Anat (2011) 0.83
Right subclavian artery aneurysm in an adolescent with a bicuspid aortic valve. Pediatr Cardiol (2012) 0.83
Dilatation of the ascending aorta in patients with congenitally bicuspid aortic valves. HSR Proc Intensive Care Cardiovasc Anesth (2012) 0.83
Selection of reference genes for quantitative real time PCR (qPCR) assays in tissue from human ascending aorta. PLoS One (2014) 0.82
Bicuspid aortic valve hemodynamics does not promote remodeling in porcine aortic wall concavity. World J Cardiol (2016) 0.81
Bicuspid aortic valve aortopathy: genetics, pathophysiology and medical therapy. Interact Cardiovasc Thorac Surg (2013) 0.81
Augmentation index and aortic stiffness in bicuspid aortic valve patients with non-dilated proximal aortas. BMC Cardiovasc Disord (2013) 0.81
Histopathology of aortic complications in bicuspid aortic valve versus Marfan syndrome: relevance for therapy? Heart Vessels (2015) 0.81
Bicuspid aortic valve and coronary anomalies. Circulation (2003) 0.81
From unicuspid to quadricuspid: influence of aortic valve morphology on aortic three-dimensional hemodynamics. J Magn Reson Imaging (2013) 0.80
Current topics on bicuspid aortic valve: clinical aspects and surgical management. Ann Thorac Cardiovasc Surg (2015) 0.80
Bicuspid aortic valve disease and ascending aortic aneurysms: gaps in knowledge. Cardiol Res Pract (2012) 0.79
Patient-specific bicuspid valve dynamics: overview of methods and challenges. J Biomech (2012) 0.79
Influence of higher valve gradient on long-term outcome after aortic valve repair. Ann Cardiothorac Surg (2013) 0.79
Isolated spontaneous dissection of the celiac trunk in a patient with bicuspid aortic valve. Vasc Health Risk Manag (2010) 0.78
Patient-specific finite element analysis of ascending aorta aneurysms. Am J Physiol Heart Circ Physiol (2015) 0.78
Bicuspid aortic valve and thoracic aortic aneurysm: three patient populations, two disease phenotypes, and one shared genotype. Cardiol Res Pract (2012) 0.78
The stretch responsive microRNA miR-148a-3p is a novel repressor of IKBKB, NF-κB signaling, and inflammatory gene expression in human aortic valve cells. FASEB J (2015) 0.78
Hereditary connective tissue diseases in young adult stroke: a comprehensive synthesis. Stroke Res Treat (2011) 0.78
MDCT differentiation between bicuspid and tricuspid aortic valves in patients with aortic valvular disease: correlation with surgical findings. Int J Cardiovasc Imaging (2011) 0.78
Role of Echocardiography Before Transcatheter Aortic Valve Implantation (TAVI). Curr Cardiol Rep (2016) 0.77
Bicuspid aortic valve: evaluation of the ability to participate in competitive sports: case reports of two soccer players. Clin Res Cardiol (2006) 0.77
Midterm results of the Ross procedure in a pediatric population: bicuspid aortic valve is not a contraindication. Pediatr Cardiol (2009) 0.77
Current indications for surgical repair in patients with bicuspid aortic valve and ascending aortic ectasia. Cardiol Res Pract (2012) 0.77
Evaluation of Cardiovascular Changes in Children with BAVs. Pediatr Cardiol (2015) 0.77
Genetics of valvular heart disease. Curr Cardiol Rep (2014) 0.77
Evaluation of myocardial strain and artery elasticity using speckle tracking echocardiography and high-resolution ultrasound in patients with bicuspid aortic valve. Int J Cardiovasc Imaging (2016) 0.76
Role of beta-blockers in Marfan's syndrome and bicuspid aortic valve: A time for re-appraisal. Ann Pediatr Cardiol (2008) 0.76
Valve mediated hemodynamics and their association with distal ascending aortic diameter in bicuspid aortic valve subjects. J Magn Reson Imaging (2017) 0.75
Heritable retinoblastoma and accelerated aortic valve disease. BMJ Case Rep (2013) 0.75
Clinical and echocardiographic determinants in bicuspid aortic dilatation: Results from a longitudinal observational study. Medicine (Baltimore) (2016) 0.75
Sciaticofemoral nerve block for varicose vein surgery in the patient with eventration of diaphragm, dextroposition of the heart and bicuspid aortic valve. J Anaesthesiol Clin Pharmacol (2012) 0.75
51-year-old man with heart murmur. Mayo Clin Proc (2010) 0.75
Identification of Reference Genes for Quantitative Real Time PCR Assays in Aortic Tissue of Syrian Hamsters with Bicuspid Aortic Valve. PLoS One (2016) 0.75
Specific circulating microRNA signature of bicuspid aortic valve disease. J Transl Med (2017) 0.75
A 40-year-old man with bicuspid aortic valve and huge LV. Heart (2015) 0.75
Single ventricle, bicuspid aorta and interatrial wall aneurysm as a rare complex adult congenital heart disease: a case report. Cases J (2009) 0.75
Molecular mechanisms of inherited thoracic aortic disease - from gene variant to surgical aneurysm. Biophys Rev (2014) 0.75
Anomalous origin and aneurysm of the right coronary artery associated with congenital bicuspid aortic valve: MDCT findings. Springerplus (2015) 0.75
Aortic shear stress in patients with bicuspid aortic valve with stenosis and insufficiency. J Thorac Cardiovasc Surg (2017) 0.75
Acute posterior circulation infarct due to bicuspid aortic valve vegetation: An uncommon stroke mechanism. Ann Indian Acad Neurol (2013) 0.75
The role of transesophageal echocardiography in aortic valve preserving procedures. Indian Heart J (2014) 0.75
A rare case of acquired aortopulmonary fistula with bicuspid aortic valve: report of successful surgical repair. BMJ Case Rep (2014) 0.75
Preliminary biomarkers for identification of human ascending thoracic aortic aneurysm. J Am Heart Assoc (2013) 0.75
Detecting aortic valve bicuspidy in patients with severe aortic valve stenosis: high diagnostic accuracy of colour Doppler transoesophageal echocardiography. Interact Cardiovasc Thorac Surg (2012) 0.75
Volumetric quantification of absolute local normalized helicity in patients with bicuspid aortic valve and aortic dilatation. Magn Reson Med (2016) 0.75
Endocardial-to-mesenchymal transformation and mesenchymal cell colonization at the onset of human cardiac valve development. Development (2015) 0.75
Aortic coarctation: the need for lifelong surveillance. Neth Heart J (2003) 0.75
Shape of the dilated aorta in children with bicuspid aortic valve. Ann Pediatr Cardiol (2013) 0.75
Characteristics of Carotid Artery Structure and Mechanical Function and Their Relationships with Aortopathy in Patients with Bicuspid Aortic Valves. Front Physiol (2017) 0.75
Association between flow skewness and aortic dilatation in patients with aortic stenosis. Int J Cardiovasc Imaging (2017) 0.75
4D Flow Analysis of BAV-Related Fluid-Dynamic Alterations: Evidences of Wall Shear Stress Alterations in Absence of Clinically-Relevant Aortic Anatomical Remodeling. Front Physiol (2017) 0.75
Clinical events and echocardiographic lesion progression rate in subjects with mild or moderate aortic regurgitation. Echo Res Pract (2017) 0.75
Aortic Valve Stenosis Alters Expression of Regional Aortic Wall Shear Stress: New Insights From a 4-Dimensional Flow Magnetic Resonance Imaging Study of 571 Subjects. J Am Heart Assoc (2017) 0.75
A case of unicuspid aortic valve associated with a single coronary artery and ventricular septal defect. J Med Ultrason (2001) (2005) 0.75
Is there evidence for statins in the treatment of aortic valve stenosis? World J Cardiol (2017) 0.75
A retrospective analysis of mitral valve pathology in the setting of bicuspid aortic valves. Echo Res Pract (2017) 0.75
A unique aortic arterial meshwork with a major aortopulmonary collateral artery, a major arteriovenous collateral artery, and a coronary arteriovenous fistula in a young man with a bicuspid aortic valve. Pediatr Cardiol (2012) 0.75
Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. J Clin Invest (2006) 4.51
Myocardial infarction accelerates atherosclerosis. Nature (2012) 4.48
Results of surgery for aortic root aneurysm in patients with Marfan syndrome. J Thorac Cardiovasc Surg (2003) 3.17
Adipokines: molecular links between obesity and atheroslcerosis. Am J Physiol Heart Circ Physiol (2005) 3.15
Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation. N Engl J Med (2015) 3.11
A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis. Circulation (2002) 2.76
Mitral valve surgery in patients with extensive calcification of the mitral annulus. J Thorac Cardiovasc Surg (2003) 2.71
True versus false left ventricular aneurysm: differentiation with MR imaging--initial experience. Radiology (2005) 2.47
New markers of inflammation and endothelial cell activation: Part I. Circulation (2003) 2.43
Chronic ischemic mitral regurgitation: repair, replace or rethink? Ann Thorac Surg (2006) 2.34
Improved heart function with myogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplantation. J Thorac Cardiovasc Surg (2002) 2.31
Hip pain and heart failure: the missing link. Can J Cardiol (2013) 2.26
Intravascular and extravascular microvessel formation in chronic total occlusions a micro-CT imaging study. JACC Cardiovasc Imaging (2010) 2.17
C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle. Circulation (2003) 2.16
Guidelines for reporting mortality and morbidity after cardiac valve interventions. Ann Thorac Surg (2008) 2.04
Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction. Circulation (2003) 2.03
Differentiation of allogeneic mesenchymal stem cells induces immunogenicity and limits their long-term benefits for myocardial repair. Circulation (2010) 2.02
Angiotensin receptor blockers and myocardial infarction. BMJ (2004) 2.02
Microplegia during coronary artery bypass grafting was associated with less low cardiac output syndrome: a propensity-matched comparison. Ann Thorac Surg (2013) 2.00
Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation. J Thorac Cardiovasc Surg (2003) 1.96
Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein. Circulation (2002) 1.94
C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function: further evidence of a mechanistic link between C-reactive protein and cardiovascular disease. Circulation (2004) 1.94
Ultrasound-targeted gene delivery induces angiogenesis after a myocardial infarction in mice. JACC Cardiovasc Imaging (2009) 1.94
Endothelial progenitor cells: new hope for a broken heart. Circulation (2003) 1.93
Cancer of the heart: epidemiology and management of primary tumors and metastases. Am J Cardiovasc Drugs (2003) 1.85
Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality. Am J Physiol Endocrinol Metab (2008) 1.79
Guidelines for reporting mortality and morbidity after cardiac valve interventions. J Thorac Cardiovasc Surg (2008) 1.76
Should the ascending aorta be replaced more frequently in patients with bicuspid aortic valve disease? J Thorac Cardiovasc Surg (2004) 1.75
In vivo 3D high-spatial-resolution MR imaging of intraplaque hemorrhage. Radiology (2008) 1.74
South Asians and cardiovascular risk: what clinicians should know. Circulation (2006) 1.74
Clinical outcomes after separate and composite replacement of the aortic valve and ascending aorta. J Thorac Cardiovasc Surg (2004) 1.71
Canada's pathology. CMAJ (2008) 1.70
Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death. J Clin Invest (2002) 1.70
Myocardial fibrosis in hypertrophic cardiomyopathy: accurate reflection of histopathological findings by CMR. JACC Cardiovasc Imaging (2013) 1.69
Enalapril increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 system. J Mol Cell Cardiol (2006) 1.69
Increasing transplanted cell survival with cell-based angiogenic gene therapy. Ann Thorac Surg (2005) 1.66
C-reactive protein upregulates complement-inhibitory factors in endothelial cells. Circulation (2004) 1.65
Histologic changes of nonbiodegradable and biodegradable biomaterials used to repair right ventricular heart defects in rats. J Thorac Cardiovasc Surg (2002) 1.64
[Brazilian Guidelines for Valve Disease - SBC 2011 / I Guideline Inter-American Valve Disease - 2011 SIAC]. Arq Bras Cardiol (2011) 1.64
Redo valvular surgery in elderly patients. Ann Thorac Surg (2009) 1.61
Inflammation and infection in nine surgically explanted Medtronic Freestyle stentless aortic valves. Cardiovasc Pathol (2007) 1.59
Microvascular function predicts cardiovascular events in primary prevention: long-term results from the Firefighters and Their Endothelium (FATE) study. Circulation (2011) 1.58
Tricuspid valve repair with an annuloplasty ring results in improved long-term outcomes. Circulation (2006) 1.56
An adult uterine hemangioblast: evidence for extramedullary self-renewal and clonal bilineage potential. Blood (2010) 1.56
Perceptions of Canadian primary care physicians towards cardiovascular risk assessment and lipid management. Can J Cardiol (2012) 1.56
Focused 2012 update of the Canadian Cardiovascular Society guidelines for the use of antiplatelet therapy. Can J Cardiol (2013) 1.54
Glitazones and heart failure: critical appraisal for the clinician. Circulation (2003) 1.53
Canadian Cardiovascular Society Consensus Conference: peripheral arterial disease - executive summary. Can J Cardiol (2005) 1.53
Relationship between carotid artery intima-media thickness and brachial artery flow-mediated dilation in middle-aged healthy men. J Am Coll Cardiol (2005) 1.53
Morphological findings in explanted Toronto stentless porcine valves. Cardiovasc Pathol (2006) 1.51
Effects of cell-based angiogenic gene therapy at 6 months: persistent angiogenesis and absence of oncogenicity. Ann Thorac Surg (2007) 1.50
New developments in the treatment of hypoplastic left heart syndrome. Pediatrics (2007) 1.49
Fundamentals of reperfusion injury for the clinical cardiologist. Circulation (2002) 1.49
Enhanced angiogenesis with multimodal cell-based gene therapy. Ann Thorac Surg (2007) 1.48
The insulin cardioplegia trial: myocardial protection for urgent coronary artery bypass grafting. J Thorac Cardiovasc Surg (2002) 1.48
Statin therapy prevents expansive remodeling in venous bypass grafts. Atherosclerosis (2012) 1.47
Mechanical stretch regimen enhances the formation of bioengineered autologous cardiac muscle grafts. Circulation (2002) 1.45
Cardiac restoration: frontier or fantasy? Can J Cardiol (2005) 1.44
Aged human cells rejuvenated by cytokine enhancement of biomaterials for surgical ventricular restoration. J Am Coll Cardiol (2012) 1.42
Suboptimal use of statin therapy in elderly patients with atherosclerosis: a population-based study. J Vasc Surg (2008) 1.42
Pulmonary pathology of severe acute respiratory syndrome in Toronto. Mod Pathol (2005) 1.41
Myometrial cells induce angiogenesis and salvage damaged myocardium. Am J Physiol Heart Circ Physiol (2006) 1.40
Sizing and tailoring the Dacron graft for reimplantation of the aortic valve. J Thorac Cardiovasc Surg (2005) 1.40
Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice. Cardiovasc Res (2007) 1.40
MicroRNA-145 targeted therapy reduces atherosclerosis. Circulation (2012) 1.39
Cardiac effects of electrical stun guns: does position of barbs contact make a difference? Pacing Clin Electrophysiol (2008) 1.39
Mitral regurgitation due to myxomatous degeneration combined with bicuspid aortic valve disease is often due to prolapse of the anterior leaflet of the mitral valve. Ann Thorac Surg (2009) 1.39
Vascular endothelial growth factor receptor upregulation in response to cell-based angiogenic gene therapy. Ann Thorac Surg (2005) 1.38
Mitral repair versus replacement for ischemic mitral regurgitation. Ann Thorac Surg (2005) 1.36
TIMP-3 deficiency leads to dilated cardiomyopathy. Circulation (2004) 1.36
Adiponectin primes human monocytes into alternative anti-inflammatory M2 macrophages. Am J Physiol Heart Circ Physiol (2010) 1.34
Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer. Eur Urol (2010) 1.32
Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis. Am J Physiol Heart Circ Physiol (2008) 1.32
Time course and cellular localization of SARS-CoV nucleoprotein and RNA in lungs from fatal cases of SARS. PLoS Med (2006) 1.31
Cardiac fibroma in adults. Cardiovasc Pathol (2010) 1.29
Intraoperative transesophageal echocardiography accurately predicts mitral valve anatomy and suitability for repair. J Am Soc Echocardiogr (2002) 1.27
Adiponectin and cardiovascular disease: state of the art? Am J Physiol Heart Circ Physiol (2006) 1.27
Effects of cocaine intoxication on the threshold for stun gun induction of ventricular fibrillation. J Am Coll Cardiol (2006) 1.26
Guidelines for reporting mortality and morbidity after cardiac valve interventions. Eur J Cardiothorac Surg (2008) 1.26
Cellular basis of endothelial dysfunction in small mesenteric arteries from spontaneously diabetic (db/db -/-) mice: role of decreased tetrahydrobiopterin bioavailability. Br J Pharmacol (2002) 1.26
Intravenously administered bone marrow cells migrate to damaged brain tissue and improve neural function in ischemic rats. Cell Transplant (2008) 1.25
Female rats are protected against fructose-induced changes in metabolism and blood pressure. Am J Physiol Heart Circ Physiol (2002) 1.24
2011 consensus statement on endomyocardial biopsy from the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology. Cardiovasc Pathol (2011) 1.24
Midterm outcomes of tricuspid valve repair versus replacement for organic tricuspid disease. Ann Thorac Surg (2006) 1.24
A comparison of mechanical properties of materials used in aortic arch reconstruction. Ann Thorac Surg (2009) 1.24