Published in Circulation on August 20, 2002
Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc Natl Acad Sci U S A (2004) 4.60
Intensive lifestyle intervention or metformin on inflammation and coagulation in participants with impaired glucose tolerance. Diabetes (2005) 2.46
Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications. Rev Endocr Metab Disord (2010) 2.19
Markers of inflammation, metabolic risk factors, and incident heart failure in American Indians: the Strong Heart Study. J Clin Hypertens (Greenwich) (2011) 2.04
Effects of human C-reactive protein on pathogenesis of features of the metabolic syndrome. Hypertension (2011) 1.71
Anti-depressant medication use and C-reactive protein: results from two population-based studies. Brain Behav Immun (2010) 1.65
Smoking cessation and cardiovascular disease risk factors: results from the Third National Health and Nutrition Examination Survey. PLoS Med (2005) 1.55
Rosuvastatin attenuates the elevation in blood pressure induced by overexpression of human C-reactive protein. Hypertens Res (2011) 1.50
Intimal redox stress: accelerated atherosclerosis in metabolic syndrome and type 2 diabetes mellitus. Atheroscleropathy. Cardiovasc Diabetol (2002) 1.46
C-reactive protein impairs coronary arteriolar dilation to prostacyclin synthase activation: role of peroxynitrite. J Mol Cell Cardiol (2009) 1.45
Orphan nuclear receptor Errγ induces C-reactive protein gene expression through induction of ER-bound Bzip transmembrane transcription factor CREBH. PLoS One (2014) 1.42
Neurokinin 3 receptor and phosphocholine transferase: missing factors for pathogenesis of C-reactive protein in preeclampsia. Hypertension (2014) 1.41
Human C-reactive protein and the metabolic syndrome. Curr Opin Lipidol (2009) 1.40
C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance. Am J Pathol (2005) 1.37
Inflammation in chronic kidney disease: role in the progression of renal and cardiovascular disease. Pediatr Nephrol (2008) 1.29
Human C-reactive protein induces endothelial dysfunction and uncoupling of eNOS in vivo. Atherosclerosis (2009) 1.26
C-reactive protein decreases endothelial nitric oxide synthase activity via uncoupling. J Mol Cell Cardiol (2007) 1.25
Effects of systemic inflammation on endothelium-dependent vasodilation. Trends Cardiovasc Med (2006) 1.24
Effects of Ramadan fasting on cardiovascular risk factors: a prospective observational study. Nutr J (2012) 1.23
Biomarkers in acute myocardial infarction. BMC Med (2010) 1.22
Cardiometabolic risk profiles and carotid atherosclerosis in individuals with prediabetes identified by fasting glucose, postchallenge glucose, and hemoglobin A1c criteria. Diabetes Care (2012) 1.16
Collaborative pooled analysis of data on C-reactive protein gene variants and coronary disease: judging causality by Mendelian randomisation. Eur J Epidemiol (2008) 1.14
C-reactive protein and 5-year survival in type 2 diabetes: the Casale Monferrato Study. Diabetes (2008) 1.11
Pathophysiological impact of cigarette smoke exposure on the cerebrovascular system with a focus on the blood-brain barrier: expanding the awareness of smoking toxicity in an underappreciated area. Int J Environ Res Public Health (2010) 1.11
Endothelial cell dysfunction and the vascular complications associated with type 2 diabetes: assessing the health of the endothelium. Vasc Health Risk Manag (2005) 1.10
Adeno-associated virus-mediated human C-reactive protein gene delivery causes endothelial dysfunction and hypertension in rats. Clin Chem (2008) 1.09
Metabolic syndrome and urologic diseases. Rev Urol (2010) 1.09
Relation between C reactive protein concentrations and coronary microvascular endothelial function. Heart (2004) 1.08
Cigarette smoke and inflammation: role in cerebral aneurysm formation and rupture. Mediators Inflamm (2012) 1.08
CRP and the risk of atherosclerotic events. Semin Immunopathol (2009) 1.06
Evidence of endothelial dysfunction in the development of Alzheimer's disease: Is Alzheimer's a vascular disorder? Am J Cardiovasc Dis (2013) 1.05
Atorvastatin restores endothelial function in normocholesterolemic smokers independent of changes in low-density lipoprotein. Circ Res (2004) 1.05
Depression and cardiac disease: epidemiology, mechanisms, and diagnosis. Cardiovasc Psychiatry Neurol (2013) 1.02
Roles of inflammation, oxidative stress, and vascular dysfunction in hypertension. Biomed Res Int (2014) 1.01
C-reactive protein is linked to lower cognitive performance in overweight and obese women. Inflammation (2008) 1.00
Inflammation, oxidative stress and renin angiotensin system in atherosclerosis. World J Biol Chem (2015) 0.99
Metabolic syndrome and benign prostatic hyperplasia: evidence of a potential relationship, hypothesized etiology, and prevention. Korean J Urol (2011) 0.98
Long-term intervention with Lactobacillus helveticus fermented milk reduces augmentation index in hypertensive subjects. Eur J Clin Nutr (2010) 0.98
Short-term physical inactivity impairs vascular function. J Surg Res (2014) 0.97
Noninvasive assessment of preclinical atherosclerosis. Vasc Health Risk Manag (2006) 0.97
Benign prostatic hyperplasia: from bench to clinic. Korean J Urol (2012) 0.96
Emerging role of PKA/eNOS pathway in therapeutic angiogenesis for ischaemic tissue diseases. Cardiovasc Res (2012) 0.96
C-reactive protein and nitric oxide levels in ischemic stroke and its subtypes: correlation with clinical outcome. Inflammation (2012) 0.94
C-reactive protein exerts angiogenic effects on vascular endothelial cells and modulates associated signalling pathways and gene expression. BMC Cell Biol (2008) 0.94
C-reactive protein is expressed and secreted by peripheral blood mononuclear cells. Clin Exp Immunol (2006) 0.94
Current tools for prediction of arteriovenous fistula outcomes. Clin Kidney J (2015) 0.94
Role of C reactive protein (CRP) in leptin resistance. Curr Pharm Des (2014) 0.93
The cooperative roles of inflammation and oxidative stress in the pathogenesis of hypertension. Antioxid Redox Signal (2013) 0.92
Inhibition of endothelial nitric oxide synthase by C-reactive protein: clinical relevance. Clin Chem (2008) 0.92
C-reactive protein impairs the endothelial glycocalyx resulting in endothelial dysfunction. Cardiovasc Res (2009) 0.92
Association of hsCRP, white blood cell count and ferritin with renal outcome in chronic kidney disease patients. PLoS One (2012) 0.92
Restenosis after percutaneous angioplasty: the role of vascular inflammation. Vasc Health Risk Manag (2005) 0.91
Atherosclerosis: humoral and cellular factors of inflammation. Virchows Arch (2005) 0.91
Inhaled nitric oxide for preterm premature rupture of membranes, oligohydramnios, and pulmonary hypoplasia. Am J Perinatol (2008) 0.91
Type 5 phosphodiesterase expression is a critical determinant of the endothelial cell angiogenic phenotype. Am J Physiol Lung Cell Mol Physiol (2008) 0.91
The combination of abdominal obesity and high-sensitivity C-reactive protein predicts new-onset hypertension in the general Japanese population: the Tanno-Sobetsu study. Hypertens Res (2015) 0.91
Humoral innate immune response and disease. Clin Immunol (2012) 0.89
Anti-tumour necrosis factor-alpha therapy over conventional therapy improves endothelial function in adults with rheumatoid arthritis. Rheumatol Int (2006) 0.89
n-3 Polyunsaturated fatty acids supplementation in peripheral artery disease: the OMEGA-PAD trial. Vasc Med (2013) 0.89
Metformin modifies the exercise training effects on risk factors for cardiovascular disease in impaired glucose tolerant adults. Obesity (Silver Spring) (2013) 0.89
C-reactive protein and vein graft disease: evidence for a direct effect on smooth muscle cell phenotype via modulation of PDGF receptor-beta. Am J Physiol Heart Circ Physiol (2008) 0.88
Should C-reactive protein be a target of therapy? Diabetes Care (2011) 0.88
Effect of moderate-intensity exercise on plasma C-reactive protein and aortic endothelial function in type 2 diabetic mice. Mediators Inflamm (2010) 0.88
Hemoglobin a1c is associated with increased risk of incident coronary heart disease among apparently healthy, nondiabetic men and women. J Am Heart Assoc (2013) 0.87
Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome. Curr Atheroscler Rep (2010) 0.87
Normal weight diabetic patients versus obese diabetics: relation of overall and abdominal adiposity to vascular health. Cardiovasc Diabetol (2014) 0.86
Prehypertensive African-American women have preserved nitric oxide and renal function but high cardiovascular risk. Kidney Blood Press Res (2010) 0.86
Critical appraisal of C-reactive protein throughout the spectrum of cardiovascular disease. Vasc Health Risk Manag (2006) 0.86
Endothelial cells, fibroblasts and vasculitis. Rheumatology (Oxford) (2005) 0.85
Association between n-3 polyunsaturated fatty acid content of red blood cells and inflammatory biomarkers in patients with peripheral artery disease. J Vasc Surg (2013) 0.84
Relationships among serum C-reactive protein, receptor for advanced glycation products, metabolic dysfunction, and cognitive impairments. BMC Neurol (2013) 0.84
Supplementation with tocotrienol-rich fraction alters the plasma levels of Apolipoprotein A-I precursor, Apolipoprotein E precursor, and C-reactive protein precursor from young and old individuals. Eur J Nutr (2013) 0.84
The vascular biology of peroxisome proliferator-activated receptors: modulation of atherosclerosis. Can J Cardiol (2006) 0.84
In vitro assessment of tobacco smoke toxicity at the BBB: do antioxidant supplements have a protective role? BMC Neurosci (2011) 0.83
Neointimal formation is reduced after arterial injury in human crp transgenic mice. Atherosclerosis (2008) 0.83
New evidences for C-reactive protein (CRP) deposits in the arterial intima as a cardiovascular risk factor. Clin Interv Aging (2008) 0.83
Noninvasive assessment of impaired endothelial function in psoriasis. Rheumatol Int (2009) 0.83
Prediction of cardiovascular events by inflammatory markers in patients undergoing carotid stenting. Mayo Clin Proc (2012) 0.83
Effect of sulfasalazine on inflammation and endothelial function in patients with established coronary artery disease. Vasc Med (2012) 0.83
Endothelial function and the regulation of muscle protein anabolism in older adults. Nutr Metab Cardiovasc Dis (2012) 0.83
The effects of xuefu zhuyu and shengmai on the evolution of syndromes and inflammatory markers in patients with unstable angina pectoris after percutaneous coronary intervention: a randomised controlled clinical trial. Evid Based Complement Alternat Med (2013) 0.82
Circulating inflammatory and endothelial markers and risk of hypertension in white and black postmenopausal women. Clin Chem (2011) 0.82
Are there race-dependent endothelial cell responses to exercise? Exerc Sport Sci Rev (2013) 0.82
Association of inflammatory markers with the morphology and extent of coronary plaque as evaluated by 64-slice multidetector computed tomography in patients with stable coronary artery disease. Int J Cardiovasc Imaging (2013) 0.82
Insulin resistance may contribute to vascular dysfunction in patients with chronic obstructive pulmonary disease. Wien Klin Wochenschr (2013) 0.81
Novel markers of peripheral arterial disease. Vasc Med (2009) 0.81
Cardiac allograft vasculopathy: diagnosis, therapy, and prognosis. Croat Med J (2014) 0.81
High-sensitivity C-reactive protein: an independent risk factor for left ventricular hypertrophy in patients with lupus nephritis. J Biomed Biotechnol (2010) 0.81
Relationship of C-reactive protein, metabolic syndrome and diabetes mellitus: potential role of statins. J Natl Med Assoc (2005) 0.81
Gender and microvascular angina. J Thromb Thrombolysis (2011) 0.81
Association of C-Reactive Protein and Metabolic Disorder in a Chinese Population. Int J Environ Res Public Health (2015) 0.81
Comparison Between Serum hsCRP and LDL Cholesterol for Search of a Better Predictor for Ischemic Heart Disease. Indian J Clin Biochem (2011) 0.80
Usefulness of C-reactive protein as a marker of early post-infarct left ventricular systolic dysfunction. Inflamm Res (2012) 0.80
Association of insulin resistance indexes to carotid intima-media thickness. PLoS One (2013) 0.80
Does vitamin D deficiency contribute to erectile dysfunction? Dermatoendocrinol (2012) 0.79
Influence of the angiotensin converting enzyme inhibitor ramipril on high-sensitivity C-reactive protein (hs-CRP) in patients with documented atherosclerosis. Z Kardiol (2005) 0.79
Targeting C-reactive protein levels using high-dose atorvastatin before coronary artery bypass graft surgery. Exp Clin Cardiol (2008) 0.78
Statin therapy in metabolic syndrome and hypertension post-JUPITER: what is the value of CRP? Curr Atheroscler Rep (2011) 0.78
Abundance- and Activity-Based Proteomics in Platelet Biology. Curr Proteomics (2011) 0.78
C-reactive protein as a predictor of cardiovascular events in elderly patients with chronic kidney disease. J Nephrol (2012) 0.78
Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. J Clin Invest (2006) 4.51
Clinical and pathophysiological implications of a bicuspid aortic valve. Circulation (2002) 3.98
Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med (2010) 3.83
Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med (2007) 3.64
Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy. Circulation (2013) 3.23
Adipokines: molecular links between obesity and atheroslcerosis. Am J Physiol Heart Circ Physiol (2005) 3.15
Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation. N Engl J Med (2015) 3.11
Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials. PLoS One (2012) 2.75
Pulmonary arterial hypertension is linked to insulin resistance and reversed by peroxisome proliferator-activated receptor-gamma activation. Circulation (2007) 2.60
Bcl-2 engineered MSCs inhibited apoptosis and improved heart function. Stem Cells (2007) 2.45
New markers of inflammation and endothelial cell activation: Part I. Circulation (2003) 2.43
Improved heart function with myogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplantation. J Thorac Cardiovasc Surg (2002) 2.31
Endovascular treatment of proximal and distal posterior inferior cerebellar artery aneurysms. J Neurosurg (2013) 2.23
C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle. Circulation (2003) 2.16
Therapeutic arteriogenesis by ultrasound-mediated VEGF165 plasmid gene delivery to chronically ischemic skeletal muscle. Circ Res (2007) 2.14
Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction. Circulation (2003) 2.03
Differentiation of allogeneic mesenchymal stem cells induces immunogenicity and limits their long-term benefits for myocardial repair. Circulation (2010) 2.02
Aneurysmal subarachnoid hemorrhage in patients under 35-years-old: a single-center experience. Clin Neurol Neurosurg (2012) 2.01
Microplegia during coronary artery bypass grafting was associated with less low cardiac output syndrome: a propensity-matched comparison. Ann Thorac Surg (2013) 2.00
Protective role of angiopoietin-1 in experimental pulmonary hypertension. Circ Res (2003) 1.98
Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation. J Thorac Cardiovasc Surg (2003) 1.96
Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein. Circulation (2002) 1.94
C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function: further evidence of a mechanistic link between C-reactive protein and cardiovascular disease. Circulation (2004) 1.94
Ultrasound-targeted gene delivery induces angiogenesis after a myocardial infarction in mice. JACC Cardiovasc Imaging (2009) 1.94
Endothelial progenitor cells: new hope for a broken heart. Circulation (2003) 1.93
Defective lung vascular development and fatal respiratory distress in endothelial NO synthase-deficient mice: a model of alveolar capillary dysplasia? Circ Res (2004) 1.83
Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality. Am J Physiol Endocrinol Metab (2008) 1.79
Should the ascending aorta be replaced more frequently in patients with bicuspid aortic valve disease? J Thorac Cardiovasc Surg (2004) 1.75
Biology of intracranial aneurysms: role of inflammation. J Cereb Blood Flow Metab (2012) 1.73
Overexpression of endothelial NO synthase induces angiogenesis in a co-culture model. Cardiovasc Res (2002) 1.71
Standards for reporting randomized controlled trials in neurosurgery. J Neurosurg (2010) 1.71
Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death. J Clin Invest (2002) 1.70
Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice. Circulation (2006) 1.69
Treatment of posterior circulation aneurysms with the pipeline embolization device. Neurosurgery (2013) 1.69
Long-term outcomes and prognostic factors in pediatric patients with severe traumatic brain injury and elevated intracranial pressure. J Neurosurg Pediatr (2008) 1.69
Perioperative management of patients undergoing transsphenoidal pituitary surgery. Anesth Analg (2005) 1.66
Influence of weekend versus weekday hospital admission on mortality following subarachnoid hemorrhage. Clinical article. J Neurosurg (2009) 1.66
Increasing transplanted cell survival with cell-based angiogenic gene therapy. Ann Thorac Surg (2005) 1.66
C-reactive protein upregulates complement-inhibitory factors in endothelial cells. Circulation (2004) 1.65
Histologic changes of nonbiodegradable and biodegradable biomaterials used to repair right ventricular heart defects in rats. J Thorac Cardiovasc Surg (2002) 1.64
Meta-analysis of the effects of endothelin receptor blockade on survival in experimental heart failure. J Card Fail (2003) 1.64
Statin use was not associated with less vasospasm or improved outcome after subarachnoid hemorrhage. Neurosurgery (2008) 1.63
An adult uterine hemangioblast: evidence for extramedullary self-renewal and clonal bilineage potential. Blood (2010) 1.56
Characterization of perioperative seizures and epilepsy following aneurysmal subarachnoid hemorrhage. J Neurosurg (2003) 1.56
Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction. Circulation (2009) 1.54
Stent-assisted coiling of intracranial aneurysms: predictors of complications, recanalization, and outcome in 508 cases. Stroke (2013) 1.54
Glitazones and heart failure: critical appraisal for the clinician. Circulation (2003) 1.53
The enzymatic degradation of hyaluronan is associated with disease progression in experimental pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2009) 1.51
Dural arteriovenous fistulas: a review of the literature and a presentation of a single institution's experience. World Neurosurg (2012) 1.50
Effects of cell-based angiogenic gene therapy at 6 months: persistent angiogenesis and absence of oncogenicity. Ann Thorac Surg (2007) 1.50
Moyamoya disorder in the United States. Neurosurgery (2012) 1.50
Fundamentals of reperfusion injury for the clinical cardiologist. Circulation (2002) 1.49