Published in Circulation on August 20, 2002
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Dimethylarginine dimethylaminohydrolase overexpression enhances insulin sensitivity. Arterioscler Thromb Vasc Biol (2008) 1.16
Insulin reduces plasma arginase activity in type 2 diabetic patients. Diabetes Care (2007) 1.10
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The phosphodiesterase-5 inhibitor vardenafil improves cardiovascular dysfunction in experimental diabetes mellitus. Br J Pharmacol (2009) 0.99
Is type 2 diabetes mellitus a vascular disease (atheroscleropathy) with hyperglycemia a late manifestation? The role of NOS, NO, and redox stress. Cardiovasc Diabetol (2003) 0.98
Asymmetric dimethylarginine (ADMA) and endothelial dysfunction: implications for atherogenesis. Clinics (Sao Paulo) (2009) 0.95
Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress. Free Radic Biol Med (2010) 0.94
Insulin resistance, metabolic stress, and atherosclerosis. Front Biosci (Schol Ed) (2012) 0.93
Asymmetric dimethylarginine is associated with developmental programming of adult kidney disease and hypertension in offspring of streptozotocin-treated mothers. PLoS One (2013) 0.93
Vaspin increases nitric oxide bioavailability through the reduction of asymmetric dimethylarginine in vascular endothelial cells. PLoS One (2012) 0.93
The effects of blocking Angiotensin receptors on early stages of diabetic nephropathy. Int J Prev Med (2012) 0.92
Dimethylarginine dimethylaminohydrolase 1 modulates endothelial cell growth through nitric oxide and Akt. Arterioscler Thromb Vasc Biol (2011) 0.92
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The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study. Cardiovasc Diabetol (2011) 0.87
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Asymmetric dimethylarginine (ADMA) is a novel emerging risk factor for cardiovascular disease and the development of renal injury in chronic kidney disease. Clin Exp Nephrol (2007) 0.86
Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2. Am J Physiol Heart Circ Physiol (2009) 0.86
Moderate exercise promotes human RBC-NOS activity, NO production and deformability through Akt kinase pathway. PLoS One (2012) 0.86
C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow. Am J Respir Cell Mol Biol (2010) 0.85
Fenofibrate decreases asymmetric dimethylarginine level in cultured endothelial cells by inhibiting NF-kappaB activity. Naunyn Schmiedebergs Arch Pharmacol (2005) 0.84
Chronic hyperglicemia and nitric oxide bioavailability play a pivotal role in pro-atherogenic vascular modifications. Genes Nutr (2007) 0.84
Protein arginine hypomethylation in a mouse model of cystathionine β-synthase deficiency. FASEB J (2014) 0.84
MicroRNA and mechanisms of impaired angiogenesis in diabetes mellitus. Circulation (2011) 0.84
Resveratrol and Cardiovascular Diseases. Nutrients (2016) 0.84
Inhibition of L-arginine metabolizing enzymes by L-arginine-derived advanced glycation end products. J Clin Biochem Nutr (2010) 0.83
Glycation of calmodulin binding domain of iNOS may increase the chance of occurrence of tuberculosis in chronic diabetic state. Bioinformation (2011) 0.83
Bioanalytical profile of the L-arginine/nitric oxide pathway and its evaluation by capillary electrophoresis. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 0.83
Asymmetrical dimethylarginine and severity of erectile dysfunction and their impact on cardiovascular events in patients with acute coronary syndrome. Arch Med Sci (2010) 0.82
Beneficial effects of inorganic nitrate/nitrite in type 2 diabetes and its complications. Nutr Metab (Lond) (2015) 0.82
Diabetic retinopathy is associated with elevated serum asymmetric and symmetric dimethylarginines. Diabetes Care (2009) 0.82
Metabolic actions of angiotensin II and insulin: a microvascular endothelial balancing act. Mol Cell Endocrinol (2012) 0.82
Endothelial function and arterial stiffness in uncomplicated type 1 diabetes and healthy controls and the impact of insulin on these parameters during an euglycemic clamp. J Diabetes Sci Technol (2007) 0.81
The endothelial ADMA/NO pathway in hypoxia-related chronic respiratory diseases. Biomed Res Int (2014) 0.81
Asymmetric dimethylarginine predicts decline of glucose tolerance in men with stable coronary artery disease: a 4.5-year follow-up study. Cardiovasc Diabetol (2013) 0.81
Arginase promotes skeletal muscle arteriolar endothelial dysfunction in diabetic rats. Front Immunol (2013) 0.80
Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury. Am J Respir Cell Mol Biol (2014) 0.80
Preconditioning c-Kit-positive Human Cardiac Stem Cells with a Nitric Oxide Donor Enhances Cell Survival through Activation of Survival Signaling Pathways. J Biol Chem (2016) 0.79
Effect of diet and omega-3 fatty acid intervention on asymmetric dimethylarginine. Nutr Metab (Lond) (2006) 0.79
Dimethylarginine dimethylaminohydrolase in rat penile tissue: reduced enzyme activity is responsible for erectile dysfunction in a rat model of atherosclerosis. Int J Impot Res (2009) 0.79
Sustained release nitrite therapy results in myocardial protection in a porcine model of metabolic syndrome with peripheral vascular disease. Am J Physiol Heart Circ Physiol (2015) 0.79
Dimethylarginines and inflammation markers in patients with chronic kidney disease undergoing dialysis. Clin Exp Med (2009) 0.78
Hypothesis: Intensive insulin therapy-induced mortality is due to excessive serotonin autoinhibition and autonomic dysregulation. World J Diabetes (2010) 0.78
Determination of the diagnostic values of asymmetric dimethylarginine as an indicator for evaluation of the endothelial dysfunction in patients with rheumatoid arthritis. Arthritis (2013) 0.78
Asymmetric dimethylarginine, a biomarker of cardiovascular complications in diabetes mellitus. World J Exp Med (2015) 0.78
DDAH1 deficiency attenuates endothelial cell cycle progression and angiogenesis. PLoS One (2013) 0.78
Protective effects of daviditin A against endothelial damage induced by lysophosphatidylcholine. Naunyn Schmiedebergs Arch Pharmacol (2003) 0.78
No effect of acute L-arginine supplementation on O₂ cost or exercise tolerance. Eur J Appl Physiol (2013) 0.78
Co-administration of Grape Seed Extract and Exercise Training Improves Endothelial Dysfunction of Coronary Vascular Bed of STZ-Induced Diabetic Rats. Iran Red Crescent Med J (2013) 0.78
4-HNE increases intracellular ADMA levels in cultured HUVECs: evidence for miR-21-dependent mechanisms. PLoS One (2013) 0.78
Asymmetric dimethylarginine plasma levels and endothelial function in newly diagnosed type 2 diabetic patients. Int J Mol Sci (2012) 0.78
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Effect of asymmetric dimethylarginine (ADMA) on heart failure development. Nitric Oxide (2016) 0.77
The ADMA-Metformin Hypothesis: Linking the Cardiovascular Consequences of the Metabolic Syndrome and Type 2 Diabetes. Cardiorenal Med (2011) 0.77
Cell-based regenerative strategies for treatment of diabetic skin wounds, a comparative study between human umbilical cord blood-mononuclear cells and calves' blood haemodialysate. PLoS One (2014) 0.76
Relation of asymmetric dimethylarginine levels to macrovascular disease and inflammation markers in type 2 diabetic patients. J Diabetes Res (2014) 0.76
Asymmetric dimethylarginine as a mediator of vascular dysfunction in cirrhosis. World J Gastroenterol (2015) 0.76
Asymmetric dimethylarginine accumulates in the kidney during ischemia/reperfusion injury. Kidney Int (2013) 0.76
New insights into acute lung injury. Vascul Pharmacol (2010) 0.76
Risk of cardiovascular diseases in diabetes mellitus and serum concentration of asymmetrical dimethylarginine. Biochem Res Int (2013) 0.76
Transient endothelial dysfunction following flow-mediated dilation assessment. Heart Vessels (2010) 0.76
Retracted Effects of coenzyme Q10 and α-lipoic acid supplementation in fructose fed rats. J Clin Biochem Nutr (2011) 0.75
Endogenous Asymmetric Dimethylarginine Pathway in High Altitude Adapted Yaks. Biomed Res Int (2015) 0.75
Involvement of DDAH/ADMA/NOS/cGMP and COX-2/PTGIS/cAMP Pathways in Human Tissue Kallikrein 1 Protecting Erectile Function in Aged Rats. PLoS One (2017) 0.75
Supplementation with Phycocyanobilin, Citrulline, Taurine, and Supranutritional Doses of Folic Acid and Biotin-Potential for Preventing or Slowing the Progression of Diabetic Complications. Healthcare (Basel) (2017) 0.75
Serum omentin and vaspin levels in cirrhotic patients with and without portal vein thrombosis. World J Gastroenterol (2017) 0.75
Nighttime BP in Elderly Individuals with Prediabetes/Diabetes with and without CKD: The HEIJO-KYO Study. Clin J Am Soc Nephrol (2016) 0.75
Association between serum levels of carotenoids and serum asymmetric dimethylarginine levels in Japanese subjects. J Epidemiol (2014) 0.75
New Insights Into Tobacco-Induced Vascular Disease: Clinical Ramifications. Methodist Debakey Cardiovasc J (2015) 0.75
Involvement of increased endogenous asymmetric dimethylarginine in the hepatic endoplasmic reticulum stress of type 2 diabetic rats. PLoS One (2014) 0.75
Asymmetric and symmetric dimethylarginine in adolescents with hyperuricemia. Dis Markers (2013) 0.75
Intercellular Adhesion Molecule and Endogenous NOS Inhibitor: Asymmetric Dimethylarginine in Pregnant Women with Gestational Diabetes Mellitus. J Diabetes Res (2016) 0.75
Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine. Circulation (2013) 3.45
Statins have biphasic effects on angiogenesis. Circulation (2002) 3.39
Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor. JAMA (2002) 3.20
Relationship between obesity, insulin resistance, and coronary heart disease risk. J Am Coll Cardiol (2002) 3.03
Activation of innate immunity is required for efficient nuclear reprogramming. Cell (2012) 2.99
Beta2-microglobulin as a biomarker in peripheral arterial disease: proteomic profiling and clinical studies. Circulation (2007) 2.72
Results of long segmental reconstruction of left anterior descending artery using left internal thoracic artery. Ann Thorac Surg (2012) 2.71
Nonbone marrow-derived circulating progenitor cells contribute to postnatal neovascularization following tissue ischemia. Circ Res (2007) 2.71
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The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae. Proc Natl Acad Sci U S A (2008) 2.30
Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine. Circulation (2003) 2.30
Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation (2007) 2.21
Malignant Transformation of Hymenolepis nana in a Human Host. N Engl J Med (2015) 2.21
A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors. J Clin Invest (2002) 2.19
Second hand smoke stimulates tumor angiogenesis and growth. Cancer Cell (2003) 2.17
Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model. Cardiovasc Res (2004) 2.05
Nitric oxide inhibition as a mechanism for blood pressure increase during salt loading in normotensive postmenopausal women. J Hypertens (2003) 2.04
Nicotine strongly activates dendritic cell-mediated adaptive immunity: potential role for progression of atherosclerotic lesions. Circulation (2003) 1.98
L-arginine supplementation in peripheral arterial disease: no benefit and possible harm. Circulation (2007) 1.97
Flow loading induces macrophage antioxidative gene expression in experimental aneurysms. Arterioscler Thromb Vasc Biol (2002) 1.96
Intestinal cestodes. Curr Opin Infect Dis (2007) 1.94
Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease. Arterioscler Thromb Vasc Biol (2011) 1.93
Symmetric dimethylarginine (SDMA) as endogenous marker of renal function--a meta-analysis. Nephrol Dial Transplant (2006) 1.90
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. J Clin Invest (2008) 1.89
Echinococcosis in Tibetan populations, western Sichuan Province, China. Emerg Infect Dis (2005) 1.89
ADMA increases arterial stiffness and decreases cerebral blood flow in humans. Stroke (2006) 1.88
Alternative ankle-brachial index method identifies additional at-risk individuals. J Am Coll Cardiol (2013) 1.86
Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence. Circulation (2003) 1.84
Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development. J Clin Invest (2012) 1.84
DNA differential diagnosis of taeniasis and cysticercosis by multiplex PCR. J Clin Microbiol (2004) 1.83
Murine model of hindlimb ischemia. J Vis Exp (2009) 1.82
Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. J Cell Biol (2009) 1.77
Multifunctional in vivo vascular imaging using near-infrared II fluorescence. Nat Med (2012) 1.74
MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion. Sci Transl Med (2012) 1.73
Endothelial progenitor cells participate in nicotine-mediated angiogenesis. J Am Coll Cardiol (2006) 1.70
Cardiometabolic risk factors and obesity: does it matter whether BMI or waist circumference is the index of obesity? Am J Clin Nutr (2013) 1.70
Does the association of the triglyceride to high-density lipoprotein cholesterol ratio with fasting serum insulin differ by race/ethnicity? Cardiovasc Diabetol (2008) 1.69
Adenoviral gene transfer with soluble vascular endothelial growth factor receptors impairs angiogenesis and perfusion in a murine model of hindlimb ischemia. Circulation (2004) 1.69
Stem cell therapy for vascular regeneration: adult, embryonic, and induced pluripotent stem cells. Circulation (2010) 1.67
Involvement of Propionibacterium acnes in the augmentation of lipogenesis in hamster sebaceous glands in vivo and in vitro. J Invest Dermatol (2009) 1.67
Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction. Circulation (2003) 1.66
Augmentation of lipogenesis by 15-deoxy-Delta12,14-prostaglandin J2 in hamster sebaceous glands: identification of cytochrome P-450-mediated 15-deoxy-Delta12,14-prostaglandin J2 production. J Invest Dermatol (2005) 1.64
MicroRNA-26a is a novel regulator of vascular smooth muscle cell function. J Cell Physiol (2011) 1.64
Cytomegalovirus infection impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine in transplant arteriosclerosis. Circulation (2004) 1.62
Dimethylarginine dimethylaminohydrolase 2 increases vascular endothelial growth factor expression through Sp1 transcription factor in endothelial cells. Arterioscler Thromb Vasc Biol (2006) 1.62
Conversion of human fibroblasts to functional endothelial cells by defined factors. Arterioscler Thromb Vasc Biol (2013) 1.61
Prevalence of insulin resistance and related risk factors for cardiovascular disease in patients with essential hypertension. Am J Hypertens (2008) 1.60
Impact of degree of obesity on surrogate estimates of insulin resistance. Diabetes Care (2004) 1.59
Trends in hyperinsulinemia among nondiabetic adults in the U.S. Diabetes Care (2006) 1.58
Discrimination between obesity and insulin resistance in the relationship with adiponectin. Diabetes (2004) 1.58
Insulin resistance and compensatory hyperinsulinemia: the key player between cigarette smoking and cardiovascular disease? J Am Coll Cardiol (2003) 1.58
Nitric oxide and angiogenesis. Circulation (2002) 1.56
Loop-mediated isothermal amplification method for differentiation and rapid detection of Taenia species. J Clin Microbiol (2008) 1.55
Alveolar echinococcosis: characterization of diagnostic antigen Em18 and serological evaluation of recombinant Em18. J Clin Microbiol (2002) 1.54
In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure. Am J Physiol Heart Circ Physiol (2007) 1.54
Utility of homeostasis model assessment of beta-cell function in predicting diabetes in 12,924 healthy Koreans. Diabetes Care (2009) 1.54
Microenvironmental VEGF distribution is critical for stable and functional vessel growth in ischemia. FASEB J (2006) 1.54
Nicotine accelerates angiogenesis and wound healing in genetically diabetic mice. Am J Pathol (2002) 1.54
Relationship to insulin resistance of the adult treatment panel III diagnostic criteria for identification of the metabolic syndrome. Diabetes (2004) 1.53
Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity. J Pharmacol Exp Ther (2010) 1.50
A prospective, multicenter, randomized trial to assess efficacy of pioglitazone on in-stent neointimal suppression in type 2 diabetes: POPPS (Prevention of In-Stent Neointimal Proliferation by Pioglitazone Study). JACC Cardiovasc Interv (2009) 1.50
Sirolimus-eluting stent versus balloon angioplasty for sirolimus-eluting stent restenosis: Insights from the j-Cypher Registry. Circulation (2010) 1.49
Embryonic stem cell-derived endothelial cells for treatment of hindlimb ischemia. J Vis Exp (2009) 1.49
Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial. Circulation (2003) 1.49
Circulating markers of abdominal aortic aneurysm presence and progression. Circulation (2008) 1.47
T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease. Circulation (2006) 1.46
Giant adrenal myelolipoma: report of a case. Surg Today (2004) 1.44
Nicotine promotes arteriogenesis. J Am Coll Cardiol (2003) 1.42
Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion. Arterioscler Thromb Vasc Biol (2010) 1.42
Determination of asymmetric dimethylarginine (ADMA) using a novel ELISA assay. Clin Chem Lab Med (2004) 1.41
Identification of endothelial cell genes by combined database mining and microarray analysis. Physiol Genomics (2003) 1.39
Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria. J Biol Chem (2004) 1.39
Abdominal aortic hemodynamics in young healthy adults at rest and during lower limb exercise: quantification using image-based computer modeling. Am J Physiol Heart Circ Physiol (2006) 1.38
Effect of metformin treatment on multiple cardiovascular disease risk factors in patients with type 2 diabetes mellitus. Metabolism (2004) 1.36
Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis. Circulation (2005) 1.35
Multiplex PCR for differential identification of broad tapeworms (Cestoda: Diphyllobothrium) infecting humans. J Clin Microbiol (2010) 1.35
Extracorporeal cardiac shock wave therapy ameliorates myocardial ischemia in patients with severe coronary artery disease. Coron Artery Dis (2006) 1.33
Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2. Circ Res (2007) 1.31
Phylogenetic systematics of the genus Echinococcus (Cestoda: Taeniidae). Int J Parasitol (2013) 1.31
Echinococcus shiquicus n. sp., a taeniid cestode from Tibetan fox and plateau pika in China. Int J Parasitol (2005) 1.30
Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells. Stem Cells (2013) 1.29
An essential role of cytosolic phospholipase A2alpha in prostaglandin E2-mediated bone resorption associated with inflammation. J Exp Med (2003) 1.29
Measurement of insulin-mediated glucose uptake: direct comparison of the modified insulin suppression test and the euglycemic, hyperinsulinemic clamp. Metabolism (2012) 1.28
Human ferritin cages for imaging vascular macrophages. Biomaterials (2010) 1.28
Genetic characterization and phylogenetic position of Echinococcus felidis (Cestoda: Taeniidae) from the African lion. Int J Parasitol (2007) 1.27
Improvement of obesity and glucose tolerance by acetate in Type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Biosci Biotechnol Biochem (2007) 1.27
State-of-the-art Echinococcus and Taenia: phylogenetic taxonomy of human-pathogenic tapeworms and its application to molecular diagnosis. Infect Genet Evol (2010) 1.27
Influences of aortic motion and curvature on vessel expansion in murine experimental aneurysms. Arterioscler Thromb Vasc Biol (2010) 1.26
Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet (2011) 1.26
Sphingosine-1-phosphate prevents tumor necrosis factor-{alpha}-mediated monocyte adhesion to aortic endothelium in mice. Arterioscler Thromb Vasc Biol (2005) 1.26
Sympatric occurrence of Taenia solium, T. saginata, and T. asiatica, Thailand. Emerg Infect Dis (2007) 1.25
Asymmetric dimethyl L-arginine (ADMA) is a critical regulator of myocardial reperfusion injury. Cardiovasc Res (2007) 1.25