A polymorphism of the brain-derived neurotrophic factor (BDNF) is associated with Alzheimer's disease in patients lacking the Apolipoprotein E epsilon4 allele.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMID 12192623)

Published in Mol Psychiatry on January 01, 2002

Authors

M Riemenschneider1, S Schwarz, S Wagenpfeil, J Diehl, U Müller, H Förstl, A Kurz

Author Affiliations

1: Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany. m.riemenschneider@lrz.tu-muenchen.de

Articles citing this

Brain-derived neurotrophic factor in neurodegenerative diseases. Nat Rev Neurol (2009) 2.93

Neurotrophic factors in Alzheimer's disease: role of axonal transport. Genes Brain Behav (2008) 1.80

Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence. Am J Med Genet B Neuropsychiatr Genet (2006) 1.41

Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response. Arch Gen Psychiatry (2009) 1.15

The role of the Met66 brain-derived neurotrophic factor allele in the recovery of executive functioning after combat-related traumatic brain injury. J Neurosci (2011) 1.14

Decreased serum brain-derived neurotrophic factor levels in elderly korean with dementia. Psychiatry Investig (2009) 1.04

Genetic variants in brain-derived neurotrophic factor associated with Alzheimer's disease. J Med Genet (2007) 1.03

A genome-wide linkage analysis of dementia in the Amish. Am J Med Genet B Neuropsychiatr Genet (2006) 1.00

Mood, memory and movement: an age-related neurodegenerative complex? Curr Aging Sci (2008) 0.93

Genetic analysis of BDNF and TrkB gene polymorphisms in Alzheimer's disease. J Neurol (2005) 0.91

Evidence for three loci modifying age-at-onset of Alzheimer's disease in early-onset PSEN2 families. Am J Med Genet B Neuropsychiatr Genet (2010) 0.90

Preservation of general intelligence following traumatic brain injury: contributions of the Met66 brain-derived neurotrophic factor. PLoS One (2014) 0.84

Association of rs6265 and rs2030324 polymorphisms in brain-derived neurotrophic factor gene with Alzheimer's disease: a meta-analysis. PLoS One (2014) 0.83

BDNF variants, premorbid educational attainment, and disease characteristics in Alzheimer's disease: an exploratory study. J Alzheimers Dis (2009) 0.80

Increased expression of TrkB and Capzb2 accompanies preserved cognitive status in early Alzheimer disease pathology. J Neuropathol Exp Neurol (2012) 0.78

Association of BDNF and BCHE with Alzheimer's disease: Meta-analysis based on 56 genetic case-control studies of 12,563 cases and 12,622 controls. Exp Ther Med (2015) 0.77

Genome scan in familial late-onset Alzheimer's disease: a locus on chromosome 6 contributes to age-at-onset. Am J Med Genet B Neuropsychiatr Genet (2013) 0.76

Influence of BDNF polymorphisms on Wilson's disease susceptibility and clinical course. Metab Brain Dis (2013) 0.75

Articles by these authors

Current concepts in mild cognitive impairment. Arch Neurol (2001) 18.09

Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. N Engl J Med (2000) 5.22

Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature (1999) 5.03

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells. Nat Cell Biol (1999) 4.98

Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines. Proc Natl Acad Sci U S A (2001) 4.79

Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex. Neuron (2001) 4.62

Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA. Science (1995) 4.59

Mutations in SDHC cause autosomal dominant paraganglioma, type 3. Nat Genet (2000) 4.55

Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumor tissue. Am J Pathol (2001) 4.18

Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors. J Virol (1995) 4.16

Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy. Nature (1986) 4.13

Acupuncture in patients with osteoarthritis of the knee: a randomised trial. Lancet (2005) 4.08

Is the unitarity of the quark-mixing CKM matrix violated in neutron beta-decay? Phys Rev Lett (2002) 3.80

Transplantation in miniature swine. I. Fixation of the major histocompatibility complex. Transplantation (1976) 3.41

Role of chromosome territories in the functional compartmentalization of the cell nucleus. Cold Spring Harb Symp Quant Biol (1993) 3.38

MHC class I expression in mice lacking the proteasome subunit LMP-7. Science (1994) 3.17

Cerebrospinal fluid tau and beta-amyloid 42 proteins identify Alzheimer disease in subjects with mild cognitive impairment. Arch Neurol (2002) 3.17

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay. J Biol Chem (1996) 3.10

Locoregional cancer treatment with magnetic drug targeting. Cancer Res (2000) 3.05

5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex. Proc Natl Acad Sci U S A (2000) 2.98

Immune defence in mice lacking type I and/or type II interferon receptors. Immunol Rev (1995) 2.97

A 70-kd protein of the yeast mitochondrial outer membrane is targeted and anchored via its extreme amino terminus. EMBO J (1984) 2.96

Selective postoperative inhibition of gastrointestinal opioid receptors. N Engl J Med (2001) 2.89

The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes. Mol Psychiatry (2006) 2.80

A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis. Cell (1993) 2.80

Transient and linear dichroism studies on bacteriorhodopsin: determination of the orientation of the 568 nm all-trans retinal chromophore. J Mol Biol (1977) 2.75

Complications following the use of the Combitube, tracheal tube and laryngeal mask airway. Anaesthesia (1999) 2.72

Mild hypothermia increases blood loss and transfusion requirements during total hip arthroplasty. Lancet (1996) 2.70

Establishment of de novo DNA methylation patterns. Transcription factor binding and deoxycytidine methylation at CpG and non-CpG sequences in an integrated adenovirus promoter. J Mol Biol (1990) 2.69

Effect of dexamethasone on the duration of interscalene nerve blocks with ropivacaine or bupivacaine. Br J Anaesth (2011) 2.63

Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. J Neurosci (2000) 2.54

A sensitive and rapid gel retention assay for nuclear factor I and other DNA-binding proteins in crude nuclear extracts. Nucleic Acids Res (1986) 2.45

CSF soluble amyloid precursor proteins in the diagnosis of incipient Alzheimer disease. Neurology (2011) 2.41

Head injury and the risk of AD in the MIRAGE study. Neurology (2000) 2.34

Distinct NF-kappa B/Rel transcription factors are responsible for tissue-specific and inducible gene activation. Nature (1993) 2.28

Theiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors. J Exp Med (1995) 2.19

Higher order structure of simian virus 40 chromatin. Science (1978) 2.16

Effects of nonsteroidal antiinflammatory drugs on inflammatory bowel disease: a case-control study. Am J Gastroenterol (2000) 2.14

Tumour necrosis factor and lymphotoxin genes map close to H-2D in the mouse major histocompatibility complex. Nature (1987) 2.13

Heat flow and distribution during induction of general anesthesia. Anesthesiology (1995) 2.12

Tau and Abeta42 protein in CSF of patients with frontotemporal degeneration. Neurology (2002) 2.12

Electric fish measure distance in the dark. Nature (1998) 2.11

Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice. J Neurosci (1999) 2.07

The first twelve amino acids of a yeast mitochondrial outer membrane protein can direct a nuclear-coded cytochrome oxidase subunit to the mitochondrial inner membrane. EMBO J (1985) 2.06

Friedreich's ataxia: point mutations and clinical presentation of compound heterozygotes. Ann Neurol (1999) 2.02

Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease. Neurology (2009) 1.99

Moderate hypothermia in the treatment of patients with severe middle cerebral artery infarction. Stroke (1998) 1.95

Early hemicraniectomy in patients with complete middle cerebral artery infarction. Stroke (1998) 1.90

Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in gamma interferon receptor or inducible nitric oxide synthase. Infect Immun (1998) 1.89

Examination of the current top candidate genes for AD in a genome-wide association study. Mol Psychiatry (2009) 1.89

Effects of the catechol-O-methyltransferase Val158Met polymorphism on executive function: a meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controls. Mol Psychiatry (2007) 1.89

Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt. Genomics (1996) 1.89

Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old? Neurology (1996) 1.85

Mild intraoperative hypothermia prolongs postanesthetic recovery. Anesthesiology (1997) 1.84

Forkhead genes in transcriptional silencing, cell morphology and the cell cycle. Overlapping and distinct functions for FKH1 and FKH2 in Saccharomyces cerevisiae. Genetics (2000) 1.82

Ondansetron is no more effective than supplemental intraoperative oxygen for prevention of postoperative nausea and vomiting. Anesth Analg (2001) 1.78

Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma. J Biol Chem (2000) 1.78

Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria. Arch Microbiol (1997) 1.77

Plasmid-mediated florfenicol resistance encoded by the floR gene in Escherichia coli isolated from cattle. Antimicrob Agents Chemother (2000) 1.77

Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney. J Cell Biol (2001) 1.77

Association of an interleukin 1 alpha polymorphism with Alzheimer's disease. Neurology (2000) 1.76

Molecular characterization, spread and evolution of multidrug resistance in Salmonella enterica typhimurium DT104. Vet Res (2001) 1.74

Evidence for a nuclear compartment of transcription and splicing located at chromosome domain boundaries. Chromosome Res (1993) 1.72

High prevalence of Echinococcus multilocularis in urban red foxes (Vulpes vulpes) and voles (Arvicola terrestris) in the city of Zürich, Switzerland. Parasitology (2000) 1.72

5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence. Nucleic Acids Res (2000) 1.71

Allergen immunotherapy: therapeutic vaccines for allergic diseases. World Health Organization. American academy of Allergy, Asthma and Immunology. Ann Allergy Asthma Immunol (1998) 1.70

Key importance of the Helicobacter pylori adherence factor blood group antigen binding adhesin during chronic gastric inflammation. Cancer Res (2001) 1.67

Biochemical and ultrastructural analysis of SV40 chromatin. Cold Spring Harb Symp Quant Biol (1978) 1.66

An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy. Nature (2001) 1.65

Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5. J Biol Chem (1996) 1.64

Prognostic and clinical relevance of pupillary responses, intracranial pressure monitoring, and brainstem auditory evoked potentials in comatose patients with acute supratentorial mass lesions. Crit Care Med (1993) 1.63

Reliability of pedicle screw assessment utilizing plain radiographs versus CT reconstruction. Eur Spine J (1997) 1.63

Familial half cryptic translocation t(9;17). J Med Genet (1994) 1.62

Metabolic engineering for microbial production of aromatic amino acids and derived compounds. Metab Eng (2001) 1.61

A genetic variation of cathepsin D is a major risk factor for Alzheimer's disease. Ann Neurol (2000) 1.61

Temperature-dependent aggregation of bacteriorhodopsin in dipalmitoyl- and dimyristoylphosphatidylcholine vesicles. J Mol Biol (1978) 1.60

Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice. J Virol (1995) 1.60

Development of the CD4 and CD8 lineage of T cells: instruction versus selection. EMBO J (1991) 1.59

Phospho-tau/total tau ratio in cerebrospinal fluid discriminates Creutzfeldt-Jakob disease from other dementias. Mol Psychiatry (2003) 1.58

Host range of the ermF rRNA methylase gene in bacteria of human and animal origin. J Antimicrob Chemother (1999) 1.57

Identification of osteopontin as a novel ligand for the integrin alpha8 beta1 and potential roles for this integrin-ligand interaction in kidney morphogenesis. Mol Biol Cell (1998) 1.57

Procalcitonin: a new parameter for the diagnosis of bacterial infection in the peri-operative period. Eur J Anaesthesiol (1998) 1.55

Immunotherapy for hymenoptera venom allergy: too expensive for European health care? Allergy (2013) 1.55

In vitro growth of murine T cells. I. Production of factors necessary for T cell growth. J Immunol (1978) 1.55

EEG coherence in Alzheimer disease. Electroencephalogr Clin Neurophysiol (1994) 1.53

An increase in serum tryptase even below 11.4 ng/mL may indicate a mast cell-mediated hypersensitivity reaction: a prospective study in Hymenoptera venom allergic patients. Clin Exp Allergy (2011) 1.51

Arteries in the posterior cervical triangle in man. Clin Anat (2005) 1.51

Crystal structure of hyaluronidase, a major allergen of bee venom. Structure (2000) 1.50