Published in Proc Natl Acad Sci U S A on August 22, 2002
Revisiting the Impact of Inversions in Evolution: From Population Genetic Markers to Drivers of Adaptive Shifts and Speciation? Annu Rev Ecol Evol Syst (2008) 2.50
A W-linked DM-domain gene, DM-W, participates in primary ovary development in Xenopus laevis. Proc Natl Acad Sci U S A (2008) 2.24
Sex determination: why so many ways of doing it? PLoS Biol (2014) 2.17
Evidence for different origin of sex chromosomes in snakes, birds, and mammals and step-wise differentiation of snake sex chromosomes. Proc Natl Acad Sci U S A (2006) 1.95
A Y-linked anti-Müllerian hormone duplication takes over a critical role in sex determination. Proc Natl Acad Sci U S A (2012) 1.74
Turnover of sex chromosomes in the stickleback fishes (gasterosteidae). PLoS Genet (2009) 1.74
Temperature-dependent sex determination in fish revisited: prevalence, a single sex ratio response pattern, and possible effects of climate change. PLoS One (2008) 1.69
Multiple sex-associated regions and a putative sex chromosome in zebrafish revealed by RAD mapping and population genomics. PLoS One (2012) 1.63
Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka. Genome Res (2006) 1.61
Tracing the emergence of a novel sex-determining gene in medaka, Oryzias luzonensis. Genetics (2012) 1.60
Establishment of a normal medakafish spermatogonial cell line capable of sperm production in vitro. Proc Natl Acad Sci U S A (2004) 1.51
The birds and the bees and the flowers and the trees: lessons from genetic mapping of sex determination in plants and animals. Genetics (2010) 1.45
Sex-specific splicing of the honeybee doublesex gene reveals 300 million years of evolution at the bottom of the insect sex-determination pathway. Genetics (2007) 1.43
Chromosome spreading of associated transposable elements and ribosomal DNA in the fish Erythrinus erythrinus. Implications for genome change and karyoevolution in fish. BMC Evol Biol (2010) 1.42
Dmrt genes in the development and evolution of sexual dimorphism. Trends Genet (2012) 1.38
DMY gene induces male development in genetically female (XX) medaka fish. Proc Natl Acad Sci U S A (2007) 1.38
Chromosomal location and gene paucity of the male specific region on papaya Y chromosome. Mol Genet Genomics (2007) 1.35
Evidence for different origins of sex chromosomes in closely related Oryzias fishes: substitution of the master sex-determining gene. Genetics (2007) 1.35
Are homologies in vertebrate sex determination due to shared ancestry or to limited options? Genome Biol (2010) 1.28
Mapping the sex determination locus in the Atlantic halibut (Hippoglossus hippoglossus) using RAD sequencing. BMC Genomics (2013) 1.28
Linkage analysis reveals the independent origin of Poeciliid sex chromosomes and a case of atypical sex inheritance in the guppy (Poecilia reticulata). Genetics (2009) 1.23
Germ cells are essential for sexual dimorphism in the medaka gonad. Proc Natl Acad Sci U S A (2007) 1.22
Molecular cytogenetic evidence of rearrangements on the Y chromosome of the threespine stickleback fish. Genetics (2008) 1.22
Zebrafish sex determination and differentiation: involvement of FTZ-F1 genes. Reprod Biol Endocrinol (2005) 1.21
Survey of repetitive sequences in Silene latifolia with respect to their distribution on sex chromosomes. Chromosome Res (2008) 1.18
DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary. Dev Biol (2011) 1.18
Sex reversal in zebrafish fancl mutants is caused by Tp53-mediated germ cell apoptosis. PLoS Genet (2010) 1.18
Wild sex in zebrafish: loss of the natural sex determinant in domesticated strains. Genetics (2014) 1.14
Mammalian sex determination—insights from humans and mice. Chromosome Res (2012) 1.14
Evolutionary dynamics of the DM domain gene family in metazoans. J Mol Evol (2003) 1.14
Mapping loci associated with tail color and sex determination in the short-lived fish Nothobranchius furzeri. Genetics (2009) 1.12
Evolution of ZZ/ZW and XX/XY sex-determination systems in the closely related medaka species, Oryzias hubbsi and O. dancena. Chromosoma (2007) 1.10
Genetic interactions controlling sex and color establish the potential for sexual conflict in Lake Malawi cichlid fishes. Heredity (Edinb) (2012) 1.07
Amh and Dmrta2 genes map to tilapia (Oreochromis spp.) linkage group 23 within quantitative trait locus regions for sex determination. Genetics (2006) 1.06
Evolution of different Y chromosomes in two medaka species, Oryzias dancena and O. latipes. Genetics (2006) 1.05
Sex-specific differences in mouse DMRT1 expression are both cell type- and stage-dependent during gonad development. Biol Reprod (2007) 1.04
The hotei mutation of medaka in the anti-Mullerian hormone receptor causes the dysregulation of germ cell and sexual development. Proc Natl Acad Sci U S A (2007) 1.04
Common spontaneous sex-reversed XX males of the medaka Oryzias latipes. Genetics (2003) 1.03
A review of sex determining mechanisms in geckos (Gekkota: Squamata). Sex Dev (2010) 1.01
Dmrt1 mutation causes a male-to-female sex reversal after the sex determination by Dmy in the medaka. Chromosome Res (2012) 1.01
Transcriptional rewiring of the sex determining dmrt1 gene duplicate by transposable elements. PLoS Genet (2010) 1.01
Different origins of ZZ/ZW sex chromosomes in closely related medaka fishes, Oryzias javanicus and O. hubbsi. Chromosome Res (2008) 1.00
Extreme heterochiasmy and nascent sex chromosomes in European tree frogs. Proc Biol Sci (2008) 0.98
A Tandem Duplicate of Anti-Müllerian Hormone with a Missense SNP on the Y Chromosome Is Essential for Male Sex Determination in Nile Tilapia, Oreochromis niloticus. PLoS Genet (2015) 0.97
Discovery and evaluation of candidate sex-determining genes and xenobiotics in the gonads of lake sturgeon (Acipenser fulvescens). Genetica (2010) 0.96
Genetics of sexual development: an evolutionary playground for fish. Genetics (2014) 0.96
Evidence for multiple sex-determining loci in Tasmanian Atlantic salmon (Salmo salar). Heredity (Edinb) (2013) 0.96
Expression profiles for six zebrafish genes during gonadal sex differentiation. Reprod Biol Endocrinol (2008) 0.95
A mammal-specific Doublesex homolog associates with male sex chromatin and is required for male meiosis. PLoS Genet (2007) 0.95
The doublesex-related gene, XDmrt4, is required for neurogenesis in the olfactory system. Proc Natl Acad Sci U S A (2005) 0.95
Analyzing the coordinated gene network underlying temperature-dependent sex determination in reptiles. Semin Cell Dev Biol (2008) 0.94
Divergent expression regulation of gonad development genes in medaka shows incomplete conservation of the downstream regulatory network of vertebrate sex determination. Mol Biol Evol (2013) 0.94
Independent fusions and recent origins of sex chromosomes in the evolution and diversification of glass knife fishes (Eigenmannia). Heredity (Edinb) (2010) 0.93
Sexual cell-fate reprogramming in the ovary by DMRT1. Curr Biol (2015) 0.92
Analysis of medaka sox9 orthologue reveals a conserved role in germ cell maintenance. PLoS One (2012) 0.92
Genomic approaches to study genetic and environmental influences on fish sex determination and differentiation. Mar Biotechnol (NY) (2012) 0.92
Gamma-ray irradiation promotes premature meiosis of spontaneously differentiating testis-ova in the testis of p53-deficient medaka (Oryzias latipes). Cell Death Dis (2012) 0.91
Wild-derived XY sex-reversal mutants in the Medaka, Oryzias latipes. Genetics (2006) 0.91
Molecular mechanisms of sex determination and gonadal sex differentiation in fish. Fish Physiol Biochem (2005) 0.91
Mice mutant in the DM domain gene Dmrt4 are viable and fertile but have polyovular follicles. Mol Cell Biol (2006) 0.91
Evolution of DMY, a newly emergent male sex-determination gene of medaka fish. Genetics (2004) 0.91
Differential gene expression in male and female rainbow trout embryos prior to the onset of gross morphological differentiation of the gonads. BMC Genomics (2011) 0.91
The genetic contribution to sex determination and number of sex chromosomes vary among populations of common frogs (Rana temporaria). Heredity (Edinb) (2016) 0.89
Sequence and gene content of a large fragment of a lizard sex chromosome and evaluation of candidate sex differentiating gene R-spondin 1. BMC Genomics (2013) 0.89
Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads. Dev Biol (2014) 0.89
The sex-specific transcriptome of the hermaphrodite sparid sharpsnout seabream (Diplodus puntazzo). BMC Genomics (2014) 0.88
Isolation and characterization of male-specific DNA markers in the rock bream Oplegnathus fasciatus. Mar Biotechnol (NY) (2012) 0.88
Comparative chromosome mapping of sex-linked genes and identification of sex chromosomal rearrangements in the Japanese wrinkled frog (Rana rugosa, Ranidae) with ZW and XY sex chromosome systems. Chromosome Res (2008) 0.88
Sex determination in the Squalius alburnoides complex: an initial characterization of sex cascade elements in the context of a hybrid polyploid genome. PLoS One (2009) 0.88
Comparative transcriptomics in East African cichlids reveals sex- and species-specific expression and new candidates for sex differentiation in fishes. Genome Biol Evol (2014) 0.88
Multiple alternative splicing in gonads of chicken DMRT1. Dev Genes Evol (2006) 0.88
Construction of two BAC libraries from half-smooth tongue sole Cynoglossus semilaevis and identification of clones containing candidate sex-determination genes. Mar Biotechnol (NY) (2009) 0.88
The genomic and genetic toolbox of the teleost medaka (Oryzias latipes). Genetics (2015) 0.87
Expression and sequence evolution of aromatase cyp19a1 and other sexual development genes in East African cichlid fishes. Mol Biol Evol (2013) 0.87
Inhibition of primordial germ cell proliferation by the medaka male determining gene Dmrt I bY. BMC Dev Biol (2007) 0.87
Molecular evolution of vertebrate sex-determining genes. Chromosome Res (2012) 0.86
Plasticity of gene-regulatory networks controlling sex determination: of masters, slaves, usual suspects, newcomers, and usurpators. EMBO Rep (2015) 0.86
Estrogen oversees the maintenance of the female genetic program in terminally differentiated gonochorists. Sci Rep (2013) 0.85
Distinct transcriptional mechanisms direct expression of the rat Dmrt1 promoter in sertoli cells and germ cells of transgenic mice. Biol Reprod (2009) 0.85
R-spondins are involved in the ovarian differentiation in a teleost, medaka (Oryzias latipes). BMC Dev Biol (2012) 0.84
A highly conserved cis-regulatory motif directs differential gonadal synexpression of Dmrt1 transcripts during gonad development. Nucleic Acids Res (2009) 0.84
Dimorphic expression of various transcription factor and steroidogenic enzyme genes during gonadal ontogeny in the air-breathing catfish, Clarias gariepinus. Sex Dev (2011) 0.84
Gonadal transcriptome analysis of male and female olive flounder (Paralichthys olivaceus). Biomed Res Int (2014) 0.83
Cladogenetic correlates of genomic expansions in the recent evolution of actinopterygiian fishes. Proc Biol Sci (2006) 0.83
Characterization of sex determination and sex differentiation genes in Latimeria. PLoS One (2013) 0.83
Additional copies of CBX2 in the genomes of males of mammals lacking SRY, the Amami spiny rat (Tokudaia osimensis) and the Tokunoshima spiny rat (Tokudaia tokunoshimensis). Chromosome Res (2011) 0.82
Mapping of five candidate sex-determining loci in rainbow trout (Oncorhynchus mykiss). BMC Genet (2009) 0.82
Conflict on the sex chromosomes: cause, effect, and complexity. Cold Spring Harb Perspect Biol (2014) 0.81
3640 unique EST clusters from the medaka testis and their potential use for identifying conserved testicular gene expression in fish and mammals. PLoS One (2008) 0.81
Molecular players involved in temperature-dependent sex determination and sex differentiation in Teleost fish. Genet Sel Evol (2014) 0.81
The Y chromosome that lost the male-determining function behaves as an X chromosome in the medaka fish, Oryzias latipes. Genetics (2008) 0.81
Development of a transient expression assay for detecting environmental oestrogens in zebrafish and medaka embryos. BMC Biotechnol (2012) 0.81
Construction of a genetic map and development of DNA markers linked to the sex-determining locus in the Patagonian pejerrey (Odontesthes hatcheri). Mar Biotechnol (NY) (2009) 0.81
Identification of a testis-enriched heat shock protein and fourteen members of Hsp70 family in the swamp eel. PLoS One (2013) 0.80
Transposable elements and early evolution of sex chromosomes in fish. Chromosome Res (2015) 0.79
Live imaging of osteoclast inhibition by bisphosphonates in a medaka osteoporosis model. Dis Model Mech (2015) 0.79
Hypoxia turns genotypic female medaka fish into phenotypic males. Ecotoxicology (2014) 0.79
Integrated analysis of miRNA and mRNA expression profiles in tilapia gonads at an early stage of sex differentiation. BMC Genomics (2016) 0.79
Vasa identifies germ cells and critical stages of oogenesis in the Asian seabass. Int J Biol Sci (2014) 0.79
Genetics and timing of sex determination in the East African cichlid fish Astatotilapia burtoni. BMC Genet (2014) 0.78
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A detailed linkage map of medaka, Oryzias latipes: comparative genomics and genome evolution. Genetics (2000) 2.19
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300 million years of conserved synteny between chicken Z and human chromosome 9. Nat Genet (1999) 1.78
Establishing sexual dimorphism: conservation amidst diversity? Nat Rev Genet (2001) 1.77
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Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers. Genes Dev (2000) 1.31
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Male specific expression suggests role of DMRT1 in human sex determination. Mech Dev (2000) 1.17
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A new submicroscopic deletion that refines the 9p region for sex reversal. Genomics (2000) 1.12
Genomic organization and expression of the doublesex-related gene cluster in vertebrates and detection of putative regulatory regions for DMRT1. Genomics (2001) 1.03
Fish retroposons related to the Penelope element of Drosophila virilis define a new group of retrotransposable elements. Mol Genet Genomics (2001) 1.02
Construction of a linkage map of the medaka (Oryzias latipes) and mapping of the Da mutant locus defective in dorsoventral patterning. Genome Res (1999) 0.92
Deletions of 9p and the quest for a conserved mechanism of sex determination. Mol Genet Metab (2000) 0.84
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst (2005) 13.00
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Epigenetic reprogramming in mouse primordial germ cells. Mech Dev (2002) 6.67
The medaka draft genome and insights into vertebrate genome evolution. Nature (2007) 5.77
Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D. Nature (2004) 5.08
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Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer. Cancer Res (2006) 4.72
Role of TBX1 in human del22q11.2 syndrome. Lancet (2003) 4.45
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Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts. Gastroenterology (2005) 3.65
Identification of eight members of the Argonaute family in the human genome. Genomics (2003) 3.55
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A unified nomenclature for the superfamily of TRP cation channels. Mol Cell (2002) 2.99
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming. Nat Genet (2009) 2.96
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Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n. Am J Hum Genet (2009) 1.96
Preoperative localization of small pulmonary lesions with a short hook wire and suture system: experience with 168 procedures. Radiology (2002) 1.96
Absence of the candidate male sex-determining gene dmrt1b(Y) of medaka from other fish species. Curr Biol (2003) 1.92
DNA sequence and analysis of human chromosome 8. Nature (2006) 1.91
Detection of EGFR gene mutation in lung cancer by mutant-enriched polymerase chain reaction assay. Clin Cancer Res (2006) 1.91
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A medaka gene map: the trace of ancestral vertebrate proto-chromosomes revealed by comparative gene mapping. Genome Res (2004) 1.89
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Determination of onset of sexual maturation and mating behavior by melanocortin receptor 4 polymorphisms. Curr Biol (2010) 1.82
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Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region. Biochem Biophys Res Commun (2003) 1.77
Novel PINK1 mutations in early-onset parkinsonism. Ann Neurol (2004) 1.72
Draft genome of the pearl oyster Pinctada fucata: a platform for understanding bivalve biology. DNA Res (2012) 1.69
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Disruption of CNTNAP2 and additional structural genome changes in a boy with speech delay and autism spectrum disorder. Neurogenetics (2009) 1.58
The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro. Hum Mol Genet (2002) 1.58
Decreased plasminogen activator inhibitor and tissue metalloproteinase inhibitor expression may promote increased metalloproteinase activity with increasing duration of human atrial fibrillation. J Cardiovasc Electrophysiol (2007) 1.57
Canine hair-follicle keratinocytes enriched with bulge cells have the highly proliferative characteristic of stem cells. Vet Dermatol (2009) 1.56
Interleukin-17 augments tumor necrosis factor-alpha-induced granulocyte and granulocyte/macrophage colony-stimulating factor release from human colonic myofibroblasts. J Gastroenterol (2005) 1.54
Ipsilateral placement in double-kidney transplantation. Transplantation (2007) 1.54
Mutational and epigenetic evidence for independent pathways for lung adenocarcinomas arising in smokers and never smokers. Cancer Res (2006) 1.53
Chronic augmentation of the parasympathetic tone to the atrioventricular node: a nonthoracotomy neurostimulation technique for ventricular rate control during atrial fibrillation. J Cardiovasc Electrophysiol (2009) 1.51
Association of cardiovascular risk factors to aortic valve calcification as quantified by electron beam computed tomography. Mayo Clin Proc (2004) 1.50
Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha. Carcinogenesis (2006) 1.49
Risk factors for reoperation after relief of congenital subaortic stenosis. Eur J Cardiothorac Surg (2008) 1.46
Aberrant promoter methylation of human DAB2 interactive protein (hDAB2IP) gene in lung cancers. Int J Cancer (2005) 1.45
Addition of a neutrophil elastase inhibitor to the organ flushing solution decreases lung reperfusion injury in rat lung transplantation. Eur J Cardiothorac Surg (2007) 1.43
Retinoic acid and Cyp26b1 are critical regulators of osteogenesis in the axial skeleton. Development (2008) 1.42
Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in breast cancer. Clin Cancer Res (2004) 1.39
Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns. Nucleic Acids Res (2010) 1.39
Selective increase of cardiac neuronal sympathetic tone: a catheter-based access to modulate left ventricular contractility. J Am Coll Cardiol (2005) 1.39
Increased nuclear factor-kappa B activation is related to the tumor development of renal cell carcinoma. Carcinogenesis (2003) 1.37
Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells. Gene (2002) 1.34
Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence. BMC Genomics (2004) 1.32
Evolutionary origin of the medaka Y chromosome. Curr Biol (2004) 1.31
Achalasia: will genetic studies provide insights? Hum Genet (2010) 1.30
A homozygous nonsense mutation in the gene for Tmem79, a component for the lamellar granule secretory system, produces spontaneous eczema in an experimental model of atopic dermatitis. J Allergy Clin Immunol (2013) 1.29
Identification and comparative expression analysis of a second wt1 gene in zebrafish. Dev Dyn (2006) 1.29
Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma. Invest Ophthalmol Vis Sci (2004) 1.28
Subfunctionalization of duplicate mitf genes associated with differential degeneration of alternative exons in fish. Genetics (2002) 1.28
Caffeic acid phenethyl ester induces apoptosis by inhibition of NFkappaB and activation of Fas in human breast cancer MCF-7 cells. J Biol Chem (2003) 1.27
Altered stratum corneum barrier and enhanced percutaneous immune responses in filaggrin-null mice. J Allergy Clin Immunol (2012) 1.26
Deep sequencing of ESTs from nacreous and prismatic layer producing tissues and a screen for novel shell formation-related genes in the pearl oyster. PLoS One (2011) 1.26
Defensin deficiency, intestinal microbes, and the clinical phenotypes of Crohn's disease. J Leukoc Biol (2004) 1.26