| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Mouse/human chimeric monoclonal antibody in man: kinetics and immune response.
|
Proc Natl Acad Sci U S A
|
1989
|
2.15
|
|
2
|
Localization of iodine-125-mIP-Des-Met14-bombesin (7-13)NH2 in ovarian carcinoma induced to express the gastrin releasing peptide receptor by adenoviral vector-mediated gene transfer.
|
J Nucl Med
|
1997
|
2.05
|
|
3
|
Phase I study of anti--epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer.
|
J Clin Oncol
|
2001
|
1.87
|
|
4
|
Use of chlorotoxin for targeting of primary brain tumors.
|
Cancer Res
|
1998
|
1.59
|
|
5
|
Blood volume redistribution during cross-clamping of the descending aorta.
|
Anesth Analg
|
1994
|
1.52
|
|
6
|
Phase I trial of iodine-131-chimeric B72.3 (human IgG4) in metastatic colorectal cancer.
|
J Nucl Med
|
1992
|
1.49
|
|
7
|
Cadmium-binding component in Escherichia coli during accommodation to low levels of this ion.
|
Appl Environ Microbiol
|
1981
|
1.49
|
|
8
|
Expression of human endogenous retrovirus k envelope transcripts in human breast cancer.
|
Clin Cancer Res
|
2001
|
1.38
|
|
9
|
Phase I single-dose study of intracavitary-administered iodine-131-TM-601 in adults with recurrent high-grade glioma.
|
J Clin Oncol
|
2006
|
1.37
|
|
10
|
Phase I trial of a recombinant vaccinia virus encoding carcinoembryonic antigen in metastatic adenocarcinoma: comparison of intradermal versus subcutaneous administration.
|
Clin Cancer Res
|
1999
|
1.15
|
|
11
|
A Phase I study of combined modality (90)Yttrium-CC49 intraperitoneal radioimmunotherapy for ovarian cancer.
|
Clin Cancer Res
|
2002
|
1.14
|
|
12
|
Phase I trial of the murine monoclonal anti-GD2 antibody 14G2a in metastatic melanoma.
|
Cancer Res
|
1992
|
1.12
|
|
13
|
Intraperitoneal radioimmunotherapy of ovarian cancer with 177Lu-CC49: a phase I/II study.
|
Gynecol Oncol
|
1997
|
1.10
|
|
14
|
A phase I study of anti-kinase insert domain-containing receptor antibody, IMC-1C11, in patients with liver metastases from colorectal carcinoma.
|
Clin Cancer Res
|
2003
|
1.09
|
|
15
|
A pilot trial of Vitaxin, a humanized anti-vitronectin receptor (anti alpha v beta 3) antibody in patients with metastatic cancer.
|
Cancer Biother Radiopharm
|
2001
|
1.06
|
|
16
|
Intraperitoneal radioimmunotherapy of ovarian cancer with lutetium-177-CC49.
|
J Nucl Med
|
1996
|
1.05
|
|
17
|
Phase I trial of the chimeric anti-GD2 monoclonal antibody ch14.18 in patients with malignant melanoma.
|
Hum Antibodies Hybridomas
|
1992
|
1.05
|
|
18
|
Patient-specific dosimetry of pretargeted radioimmunotherapy using CC49 fusion protein in patients with gastrointestinal malignancies.
|
J Nucl Med
|
2005
|
1.00
|
|
19
|
Characterization of a mouse/human chimeric monoclonal antibody (17-1A) to a colon cancer tumor-associated antigen.
|
J Immunol
|
1987
|
0.98
|
|
20
|
Monitoring method for surface contamination caused by selected antineoplastic agents.
|
Am J Health Syst Pharm
|
2002
|
0.96
|
|
21
|
Expression of CEA, Tag-72, and Lewis-Y antigen in primary and metastatic lesions of ovarian carcinoma.
|
Hum Pathol
|
2003
|
0.94
|
|
22
|
Mouse/human chimeric antibodies to a tumor-associated antigen: biologic activity of the four human IgG subclasses.
|
J Natl Cancer Inst
|
1988
|
0.93
|
|
23
|
Radiation dosimetry of 131I-chlorotoxin for targeted radiotherapy in glioma-bearing mice.
|
J Neurooncol
|
2005
|
0.92
|
|
24
|
Initial evaluation of human monoclonal anti-lipid A antibody (HA-1A) in patients with sepsis syndrome.
|
Crit Care Med
|
1990
|
0.91
|
|
25
|
Treatment of metastatic prostate carcinoma with radiolabeled antibody CC49.
|
J Nucl Med
|
1994
|
0.91
|
|
26
|
Synthesis and biological evaluation of paclitaxel-C225 conjugate as a model for targeted drug delivery.
|
Bioconjug Chem
|
2003
|
0.90
|
|
27
|
Paclitaxel derivatives for targeted therapy of cancer: toward the development of smart taxanes.
|
J Med Chem
|
1999
|
0.89
|
|
28
|
Improved synthesis of the bifunctional chelating agent 1,4,7,10-tetraaza-N-(1-carboxy-3-(4-nitrophenyl)propyl)-N',N'',N'''-tri s(acetic acid)cyclododecane (PA-DOTA).
|
Bioorg Med Chem
|
1999
|
0.89
|
|
29
|
Intraperitoneal radioimmunochemotherapy of ovarian cancer: a phase I study.
|
Cancer Biother Radiopharm
|
2001
|
0.89
|
|
30
|
Targeting strategies for cancer radiotherapy.
|
Clin Cancer Res
|
1999
|
0.87
|
|
31
|
Development of an HPLC method for simultaneous analysis of five antineoplastic agents.
|
Appl Occup Environ Hyg
|
2003
|
0.87
|
|
32
|
Phase I trial of multiple large doses of murine monoclonal antibody CO17-1A. I. Clinical aspects.
|
J Natl Cancer Inst
|
1988
|
0.87
|
|
33
|
Pilot study using a humanized CC49 monoclonal antibody (HuCC49DeltaCH2) to localize recurrent colorectal carcinoma.
|
Ann Surg Oncol
|
2004
|
0.85
|
|
34
|
Phase II study of dual 131I-labeled monoclonal antibody therapy with interferon in patients with metastatic colorectal cancer.
|
Clin Cancer Res
|
1996
|
0.84
|
|
35
|
Phase I clinical trial of CO17-1A monoclonal antibody.
|
Hybridoma
|
1986
|
0.84
|
|
36
|
Fractionated radioimmunotherapy of human colon carcinoma xenografts with 131I-labeled monoclonal antibody CC49.
|
Cancer Res
|
1995
|
0.84
|
|
37
|
A new monitoring method using solid sorbent media for evaluation of airborne cyclophosphamide and other antineoplastic agents.
|
Appl Occup Environ Hyg
|
2003
|
0.84
|
|
38
|
Phase I trial of an anti-CD19 deglycosylated ricin A chain immunotoxin in non-Hodgkin's lymphoma: effect of an intensive schedule of administration.
|
J Immunother Emphasis Tumor Immunol
|
1995
|
0.83
|
|
39
|
Idiotypic vaccination with a murine anti-dsDNA antibody: phase I study in patients with nonactive systemic lupus erythematosus with nephritis.
|
J Rheumatol
|
1999
|
0.83
|
|
40
|
A phase I clinical trial of murine monoclonal antibody D612 in patients with metastatic gastrointestinal cancer.
|
Cancer Res
|
1993
|
0.83
|
|
41
|
Enhancement of radiolabeled antibody binding and tumor localization through adenoviral transduction of the human carcinoembryonic antigen gene.
|
Gene Ther
|
1996
|
0.83
|
|
42
|
Growth-inhibitory effects of coumarin (1,2-benzopyrone) and 7-hydroxycoumarin on human malignant cell lines in vitro.
|
J Cancer Res Clin Oncol
|
1994
|
0.83
|
|
43
|
Pretargeted radioimmunotherapy (RIT) with a novel anti-TAG-72 fusion protein.
|
Cancer Biother Radiopharm
|
2005
|
0.82
|
|
44
|
Phase II study of interferon-enhanced 131I-labeled high affinity CC49 monoclonal antibody therapy in patients with metastatic prostate cancer.
|
Clin Cancer Res
|
1999
|
0.82
|
|
45
|
Improved prediction of myelotoxicity using a patient-specific imaging dose estimate for non-marrow-targeting (90)Y-antibody therapy.
|
J Nucl Med
|
2002
|
0.81
|
|
46
|
Phase I study of 90Y-CC49 monoclonal antibody therapy in patients with advanced non-small cell lung cancer: effect of chelating agents and paclitaxel co-administration.
|
Cancer Biother Radiopharm
|
2005
|
0.81
|
|
47
|
Phase I clinical and pharmacological study of suppression of human antimouse antibody response to monoclonal antibody L6 by deoxyspergualin.
|
Cancer Res
|
1995
|
0.81
|
|
48
|
Production of a single chain anti-CEA antibody from the hybridoma cell line T84.66 using a modified colony-lift selection procedure to detect antigen-positive ScFv bacterial clones.
|
Hybridoma
|
1998
|
0.81
|
|
49
|
An advanced solid support for immunoassays and other affinity applications.
|
Biotechniques
|
1993
|
0.80
|
|
50
|
Radioimmunoassay of free beta-subunit of human chorionic gonadotropin as a prognostic test for persistent trophoblastic disease in molar pregnancy.
|
Am J Obstet Gynecol
|
1986
|
0.80
|
|
51
|
Phase Ia/Ib trial of anti-GD2 chimeric monoclonal antibody 14.18 (ch14.18) and recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) in metastatic melanoma.
|
J Immunother Emphasis Tumor Immunol
|
1996
|
0.80
|
|
52
|
Initial clinical evaluation of iodine-125-labeled chimeric 17-1A for metastatic colon cancer.
|
J Nucl Med
|
1995
|
0.80
|
|
53
|
Intraperitoneal pretarget radioimmunotherapy with CC49 fusion protein.
|
Clin Cancer Res
|
2005
|
0.79
|
|
54
|
Evaluation of human anti-mouse antibody response in normal volunteers following repeated injections of fanolesomab (NeutroSpec), a murine anti-CD15 IgM monoclonal antibody for imaging infection.
|
Nucl Med Commun
|
2004
|
0.79
|
|
55
|
Approaches to enhance cancer radiotherapy employing gene transfer methods.
|
Gene Ther
|
1996
|
0.79
|
|
56
|
Site-specifically traced drug release and biodistribution of a paclitaxel-antibody conjugate toward improvement of the linker structure.
|
Bioconjug Chem
|
2004
|
0.79
|
|
57
|
A phase II trial of murine monoclonal antibody 17-1A and interferon-gamma: clinical and immunological data.
|
Cancer Immunol Immunother
|
1990
|
0.79
|
|
58
|
Generation of a human anti-idiotypic antibody that mimics the GD2 antigen.
|
J Immunol
|
1993
|
0.78
|
|
59
|
Synthesis of bombesin analogues for radiolabeling with rhenium-188.
|
Cancer
|
1997
|
0.78
|
|
60
|
Direct quantitation of IgG subclasses 1, 2, and 3 bound to red cells by Rh1 (D) antibodies.
|
Transfusion
|
1988
|
0.78
|
|
61
|
Polynucleotide immunization of nonhuman primates against carcinoembryonic antigen.
|
Clin Cancer Res
|
1998
|
0.78
|
|
62
|
Phase II trial of murine monoclonal antibody D612 combined with recombinant human monocyte colony-stimulating factor (rhM-CSF) in patients with metastatic gastrointestinal cancer.
|
Cancer Res
|
1995
|
0.78
|
|
63
|
Direct localization comparison of murine and chimeric B72.3 antibodies in patients with colon cancer.
|
Hum Antibodies Hybridomas
|
1993
|
0.77
|
|
64
|
Intraperitoneal radioimmunotherapy with a humanized anti-TAG-72 (CC49) antibody with a deleted CH2 region.
|
Cancer Biother Radiopharm
|
2005
|
0.77
|
|
65
|
Comparison of multiple bolus and continuous injections of 131I-labeled CC49 for therapy in a colon cancer xenograft model.
|
Clin Cancer Res
|
1999
|
0.77
|
|
66
|
Biodistribution study of 188Re-labeled trisuccin-HuCC49 and trisuccin-HuCC49deltaCh2 conjugates in athymic nude mice bearing intraperitoneal colon cancer xenografts.
|
Clin Cancer Res
|
1999
|
0.77
|
|
67
|
Adenoviral-mediated delivery of gastrin-releasing peptide receptor results in specific tumor localization of a bombesin analogue in vivo.
|
Clin Cancer Res
|
1997
|
0.77
|
|
68
|
Radiometric assay for direct quantitation of rat liver cytochrome P-450b using monoclonal antibodies.
|
Anal Biochem
|
1985
|
0.77
|
|
69
|
Amniotic fluid levels of human chorionic gonadotropin and its alpha and beta subunits in second-trimester chromosomally abnormal pregnancies.
|
Prenat Diagn
|
1992
|
0.76
|
|
70
|
Further studies on the protein conjugation of hydroxamic acid bifunctional chelating agents: group-specific conjugation at two different loci.
|
Bioconjug Chem
|
1999
|
0.76
|
|
71
|
SEREX analysis for tumor antigen identification in a mouse model of adenocarcinoma.
|
Cancer Gene Ther
|
2000
|
0.76
|
|
72
|
Sequential use of indium-111 labeled monoclonal antibodies 96.5 and ZME-018 does not increase detection sensitivity for metastatic melanoma.
|
Clin Nucl Med
|
1989
|
0.76
|
|
73
|
Synthesis of N-[tris[2-[[N-(benzyloxy)amino]carbonyl]ethyl]methyl]succinamic acid, trisuccin. Hydroxamic acid derivatives as a new class of bifunctional chelating agents.
|
Bioconjug Chem
|
1993
|
0.76
|
|
74
|
Dose fractionation of radiolabeled antibodies in patients with metastatic colon cancer.
|
J Nucl Med
|
1992
|
0.76
|
|
75
|
Comparison of methods for predicting myelotoxicity for non-marrow targeting I-131-antibody therapy.
|
Cancer Biother Radiopharm
|
2003
|
0.75
|
|
76
|
Quality control of radiolabeled monoclonal antibodies.
|
Cancer Biother Radiopharm
|
2000
|
0.75
|
|
77
|
Limited sampling models for HA-1A IgM monoclonal antibody.
|
Hum Antibodies Hybridomas
|
1990
|
0.75
|
|
78
|
Correlation of toxicity with treatment parameters for 131I-CC49 radioimmunotherapy in three phase II clinical trials.
|
Cancer Biother Radiopharm
|
1997
|
0.75
|
|
79
|
In-111 labeled monoclonal anti-carcinoembryonic antigen antibody (ZCE025) in the immunoscintigraphic imaging of metastatic antigen-producing adenocarcinomas.
|
Clin Nucl Med
|
1991
|
0.75
|
|
80
|
Pharmacokinetics of a mouse/human chimeric monoclonal antibody (C-17-1A) in metastatic adenocarcinoma patients.
|
Pharm Res
|
1990
|
0.75
|
|
81
|
Phase II multicenter evaluation of prolonged murine monoclonal antibody 17-1A therapy in pancreatic carcinoma.
|
J Immunother Emphasis Tumor Immunol
|
1993
|
0.75
|
|
82
|
Suppression of human anti-mouse antibody response to murine monoclonal antibody L6 by deoxyspergualin: a phase I study.
|
Adv Exp Med Biol
|
1994
|
0.75
|
|
83
|
Lack of T-cell immunity in humans with preexisting anti-mouse immunoglobulin reactivity.
|
Cancer Res
|
1992
|
0.75
|
|
84
|
Testicular uptake and radiation dose in patients receiving Zevalin and Pretarget CC49Fusion protein.
|
Cancer Biother Radiopharm
|
2005
|
0.75
|
|
85
|
Cardiac electrophysiologic effects of acute and chronic amiodarone administration in the isolated perfused rabbit heart: altered thyroid hormone metabolism.
|
J Pharmacol Exp Ther
|
1986
|
0.75
|
|
86
|
Radioimmunoscintigraphic detection of occult gestational choriocarcinoma.
|
Am J Obstet Gynecol
|
1987
|
0.75
|
|
87
|
Selection of monoclonal antibody to hCG which localizes in human choriocarcinoma growing in the Syrian hamster cheek pouch.
|
Hybridoma
|
1984
|
0.75
|
|
88
|
Choriocarcinoma: blocking factor and monoclonal antibody iodine 131 imaging.
|
Am J Obstet Gynecol
|
1984
|
0.75
|
|
89
|
Sensitization of radiolabeled monoclonal antibody therapy using bromodeoxyuridine.
|
Cancer
|
1994
|
0.75
|
|
90
|
Monoclonal antibodies against beta-human chorionic gonadotropin. A comparative immunohistochemical study.
|
Arch Pathol Lab Med
|
1984
|
0.75
|
|
91
|
An animal model to predict the immunogenicity of murine V regions in humans.
|
Hum Antibodies Hybridomas
|
1993
|
0.75
|
|
92
|
Production of mouse monoclonal anti-idiotypic antibodies specific to epitopes of tumor-associated mucin TAG-12.
|
Hybridoma
|
1994
|
0.75
|
|
93
|
Development and characterization of a monoclonal antibody which distinguishes the beta-subunit of human chorionic gonadotropin (beta hCG) in the presence of the hCG.
|
Endocrinology
|
1981
|
0.75
|
|
94
|
Comparison of biodistribution, dosimetry, and outcome from clinical trials of radionuclide-CC49 antibody therapy.
|
Cancer Biother Radiopharm
|
2003
|
0.75
|
|
95
|
Isolated ectopic production of the free beta subunit of chorionic gonadotropin by an epidermoid carcinoma of unknown primary site.
|
Cancer
|
1985
|
0.75
|
|
96
|
A novel monoclonal antibody design for radioimmunotherapy.
|
Cancer Biother Radiopharm
|
2003
|
0.75
|
|
97
|
Changes in cardiac muscle function and biochemistry produced by long-term amiodarone and amiodarone + triiodothyronine administration in the rabbit.
|
Pharmacology
|
1987
|
0.75
|
|
98
|
Development and characterization of a monoclonal antibody to human embryonal carcinoma.
|
J Urol
|
1987
|
0.75
|