Published in Lancet on August 10, 2002
A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet (2006) 9.56
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The IL12B gene is associated with asthma. Am J Hum Genet (2004) 1.29
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The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes. BMC Med Genet (2007) 1.10
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Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population. Am J Hum Genet (2013) 0.91
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Functional genetic polymorphisms in interleukin-12B gene in association with systemic lupus erythematosus. Rheumatol Int (2010) 0.80
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No association of IL-12p40 pro1.1 polymorphism with juvenile idiopathic arthritis. Pediatr Rheumatol Online J (2015) 0.75
1L12B promoter polymorphism and asthma. Lancet (2002) 0.75
A replication study of the association between the IL12B promoter allele CTCTAA and susceptibility to cerebral malaria in Thai population. Malar J (2009) 0.75
Increased expression of IL12B mRNA transcribed from the risk haplotype for Crohn's disease is a risk factor for disease relapse in Japanese patients. J Gastroenterol (2017) 0.75
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An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool children. Am J Respir Crit Care Med (2007) 4.10
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Bronchiectasis in infants and preschool children diagnosed with cystic fibrosis after newborn screening. J Pediatr (2009) 2.31
Early identification of atopy in the prediction of persistent asthma in children. Lancet (2008) 2.27
Modulation of DNA methylation states and infant immune system by dietary supplementation with ω-3 PUFA during pregnancy in an intervention study. Am J Clin Nutr (2013) 2.20
Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO- T cells. J Immunol (2002) 2.19
Vitamin D deficiency at 16 to 20 weeks' gestation is associated with impaired lung function and asthma at 6 years of age. Ann Am Thorac Soc (2014) 2.14
Risk assessment for respiratory complications in paediatric anaesthesia: a prospective cohort study. Lancet (2010) 2.11
Maternal serum vitamin D levels during pregnancy and offspring neurocognitive development. Pediatrics (2012) 1.97
Interactions between innate antiviral and atopic immunoinflammatory pathways precipitate and sustain asthma exacerbations in children. J Immunol (2009) 1.97
The long-term effects of breastfeeding on child and adolescent mental health: a pregnancy cohort study followed for 14 years. J Pediatr (2009) 1.90
Anatomical location determines the distribution and function of dendritic cells and other APCs in the respiratory tract. J Immunol (2005) 1.89
Persistent effects of maternal smoking during pregnancy on lung function and asthma in adolescents. Am J Respir Crit Care Med (2014) 1.68
Support for 2 variants of eczema. J Allergy Clin Immunol (2005) 1.65
Development of interleukin-12-producing capacity throughout childhood. Infect Immun (2002) 1.65
Allergen-enhanced thrombomodulin (blood dendritic cell antigen 3, CD141) expression on dendritic cells is associated with a TH2-skewed immune response. J Allergy Clin Immunol (2008) 1.62
Early respiratory infection is associated with reduced spirometry in children with cystic fibrosis. Am J Respir Crit Care Med (2014) 1.60
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nat Genet (2011) 1.60
Interpretation of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine is adversely affected by methodological inaccuracies when using a commercial ELISA. Free Radic Biol Med (2010) 1.60
Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets. Circ Res (2014) 1.54
Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: a randomized, controlled trial. J Allergy Clin Immunol (2003) 1.50
Reversal of airway hyperresponsiveness by induction of airway mucosal CD4+CD25+ regulatory T cells. J Exp Med (2006) 1.50
Low maternal serum vitamin D during pregnancy and the risk for postpartum depression symptoms. Arch Womens Ment Health (2014) 1.49
Bullying in children and adolescents: a modifiable risk factor for mental illness. Aust N Z J Psychiatry (2013) 1.48
TLR4 polymorphisms mediate impaired responses to respiratory syncytial virus and lipopolysaccharide. J Immunol (2007) 1.46
Assessment of respiratory mechanics with forced oscillations in healthy newborns. Pediatr Pulmonol (2014) 1.43
Contemporaneous maturation of immunologic and respiratory functions during early childhood: implications for development of asthma prevention strategies. J Allergy Clin Immunol (2005) 1.42
Accelerated antigen sampling and transport by airway mucosal dendritic cells following inhalation of a bacterial stimulus. J Immunol (2006) 1.41
Adolescent dietary patterns are associated with lifestyle and family psycho-social factors. Public Health Nutr (2009) 1.40
Assessing adherence and factors associated with adherence in young children with asthma. Respirology (2008) 1.38
Breast feeding and cognitive development in childhood: a prospective birth cohort study. Paediatr Perinat Epidemiol (2003) 1.37
Postnatal development of monocyte cytokine responses to bacterial lipopolysaccharide. Pediatr Res (2007) 1.36
Functional maturation of CD4+CD25+CTLA4+CD45RA+ T regulatory cells in human neonatal T cell responses to environmental antigens/allergens. J Immunol (2004) 1.35
Lung function in infants with cystic fibrosis diagnosed by newborn screening. Am J Respir Crit Care Med (2008) 1.31
Association between socioeconomic status and the development of asthma: analyses of income trajectories. Am J Public Health (2009) 1.31
Exhaled breath malondialdehyde as a marker of effect of exposure to air pollution in children with asthma. J Allergy Clin Immunol (2008) 1.29
Prenatal versus postnatal sensitization to environmental allergens in a high-risk birth cohort. J Allergy Clin Immunol (2007) 1.25
Toward improved prediction of risk for atopy and asthma among preschoolers: a prospective cohort study. J Allergy Clin Immunol (2010) 1.25
Pre- and postnatal influences on preschool mental health: a large-scale cohort study. J Child Psychol Psychiatry (2008) 1.23
Viral infections and atopy in asthma pathogenesis: new rationales for asthma prevention and treatment. Nat Med (2012) 1.22
Systemic responsiveness to lipopolysaccharide and polymorphisms in the toll-like receptor 4 gene in human beings. J Allergy Clin Immunol (2003) 1.20
Do early-life viral infections cause asthma? J Allergy Clin Immunol (2010) 1.16
Children's health in Latin America: the influence of environmental exposures. Environ Health Perspect (2014) 1.15
Induction of asthma and the environment: what we know and need to know. Environ Health Perspect (2006) 1.15
Polymorphisms in cytokine genes define subpopulations of HIV-1 patients who experienced immune restoration diseases. AIDS (2002) 1.15
Lifecourse childhood adiposity trajectories associated with adolescent insulin resistance. Diabetes Care (2011) 1.14
A meta-analysis of core stability exercise versus general exercise for chronic low back pain. PLoS One (2012) 1.12
CpG methylation patterns in the IFNgamma promoter in naive T cells: variations during Th1 and Th2 differentiation and between atopics and non-atopics. Pediatr Allergy Immunol (2006) 1.12
Airway epithelial cells regulate the functional phenotype of locally differentiating dendritic cells: implications for the pathogenesis of infectious and allergic airway disease. J Immunol (2009) 1.11
Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity. J Immunol (2005) 1.11
Virus infection and allergy in the development of asthma: what is the connection? Curr Opin Allergy Clin Immunol (2012) 1.10
Interleukin-10/interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family history. Am J Respir Crit Care Med (2008) 1.10
Airway dendritic cells: co-ordinators of immunological homeostasis and immunity in the respiratory tract. APMIS (2003) 1.10
Environmental threats to children's health in Southeast Asia and the Western Pacific. Environ Health Perspect (2003) 1.09
Th2-associated local reactions to the acellular diphtheria-tetanus-pertussis vaccine in 4- to 6-year-old children. Infect Immun (2005) 1.09
Gene polymorphisms, breast-feeding, and development of food sensitization in early childhood. J Allergy Clin Immunol (2011) 1.08
Air trapping on chest CT is associated with worse ventilation distribution in infants with cystic fibrosis diagnosed following newborn screening. PLoS One (2011) 1.08
High IFN-gamma production by CD8+ T cells and early sensitization among infants at high risk of atopy. J Allergy Clin Immunol (2004) 1.08
Providing feedback on adherence increases use of preventive medication by asthmatic children. J Asthma (2010) 1.07
Synergy between adiposity, insulin resistance, metabolic risk factors, and inflammation in adolescents. Diabetes Care (2009) 1.06
Exposure to environmental tobacco smoke in cars increases the risk of persistent wheeze in adolescents. Med J Aust (2007) 1.06
Identification of novel Th2-associated genes in T memory responses to allergens. J Immunol (2006) 1.06
Prevention of allergic respiratory disease in infants: current aspects and future perspectives. Curr Opin Allergy Clin Immunol (2007) 1.06
Breastfeeding and overweight: longitudinal analysis in an Australian birth cohort. J Pediatr (2005) 1.05