PubRank

Jörg J Goronzy

Author PubWeight™ 139.35‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The influence of age on T cell generation and TCR diversity. J Immunol 2005 4.36
2 Medium- and large-vessel vasculitis. N Engl J Med 2003 3.96
3 Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids: a double-blind, placebo-controlled, randomized prospective clinical trial. Arthritis Rheum 2006 3.64
4 Giant-cell arteritis and polymyalgia rheumatica. Ann Intern Med 2003 3.48
5 Clinical practice. Giant-cell arteritis and polymyalgia rheumatica. N Engl J Med 2014 3.46
6 HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group. J Acquir Immune Defic Syndr 2012 2.95
7 T cell subset-specific susceptibility to aging. Clin Immunol 2008 2.42
8 The immunopathology of giant cell arteritis: diagnostic and therapeutic implications. J Neuroophthalmol 2012 2.19
9 Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity. Nat Med 2012 2.19
10 Vessel-specific Toll-like receptor profiles in human medium and large arteries. Circulation 2008 1.91
11 Th17 and Th1 T-cell responses in giant cell arteritis. Circulation 2010 1.88
12 Therapeutic effects of acetylsalicylic acid in giant cell arteritis. Arthritis Rheum 2002 1.80
13 Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha. Circulation 2006 1.77
14 Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque. Circ Res 2006 1.77
15 BLyS and APRIL in rheumatoid arthritis. J Clin Invest 2005 1.75
16 Regulation of T cell receptor signaling by activation-induced zinc influx. J Exp Med 2011 1.73
17 T-cell-mediated lysis of endothelial cells in acute coronary syndromes. Circulation 2002 1.72
18 Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis. J Exp Med 2004 1.70
19 Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension. Circulation 2010 1.68
20 Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages. Proc Natl Acad Sci U S A 2003 1.65
21 T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome. Circ Res 2006 1.62
22 Epigenetic regulation of killer immunoglobulin-like receptor expression in T cells. Blood 2009 1.62
23 Homeostatic control of T-cell generation in neonates. Blood 2003 1.62
24 Immune activation caused by vascular oxidation promotes fibrosis and hypertension. J Clin Invest 2015 1.55
25 Telomerase insufficiency in rheumatoid arthritis. Proc Natl Acad Sci U S A 2009 1.54
26 Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis. J Exp Med 2009 1.54
27 NADPH oxidase deficiency underlies dysfunction of aged CD8+ Tregs. J Clin Invest 2016 1.53
28 TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque. J Exp Med 2006 1.48
29 Immune mechanisms in medium and large-vessel vasculitis. Nat Rev Rheumatol 2013 1.48
30 T-cell senescence: a culprit of immune abnormalities in chronic inflammation and persistent infection. Trends Mol Med 2004 1.47
31 Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaque. Circulation 2007 1.47
32 Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study. Arthritis Res Ther 2005 1.38
33 Immunosenescence, autoimmunity, and rheumatoid arthritis. Exp Gerontol 2003 1.38
34 CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis. J Exp Med 2002 1.38
35 Toll-like receptors 4 and 5 induce distinct types of vasculitis. Circ Res 2009 1.37
36 Vessel wall-embedded dendritic cells induce T-cell autoreactivity and initiate vascular inflammation. Circ Res 2008 1.35
37 Functional profile of activated dendritic cells in unstable atherosclerotic plaque. Basic Res Cardiol 2006 1.34
38 Rejuvenating the immune system in rheumatoid arthritis. Nat Rev Rheumatol 2009 1.29
39 Simvastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo. Atherosclerosis 2006 1.26
40 IFN-γ and IL-17: the two faces of T-cell pathology in giant cell arteritis. Curr Opin Rheumatol 2011 1.26
41 Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis. Arthritis Rheum 2008 1.25
42 Inhibitory CD8+ T cells in autoimmune disease. Hum Immunol 2008 1.23
43 DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis. EMBO Mol Med 2010 1.23
44 Stimulatory killer Ig-like receptors modulate T cell activation through DAP12-dependent and DAP12-independent mechanisms. J Immunol 2004 1.23
45 Telomeres and immunological diseases of aging. Gerontology 2009 1.22
46 Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis. J Immunol 2007 1.22
47 CD28 loss in senescent CD4+ T cells: reversal by interleukin-12 stimulation. Blood 2002 1.21
48 Immunopathways in giant cell arteritis and polymyalgia rheumatica. Autoimmun Rev 2004 1.20
49 Telomere dysfunction, autoimmunity and aging. Aging Dis 2011 1.20
50 Trapping of misdirected dendritic cells in the granulomatous lesions of giant cell arteritis. Am J Pathol 2002 1.19
51 Selective activation of the c-Jun NH2-terminal protein kinase signaling pathway by stimulatory KIR in the absence of KARAP/DAP12 in CD4+ T cells. J Exp Med 2003 1.18
52 The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis. Arthritis Res Ther 2005 1.17
53 Formation of the killer Ig-like receptor repertoire on CD4+CD28null T cells. J Immunol 2002 1.15
54 De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes. Circ Res 2003 1.15
55 Vascular dendritic cells in giant cell arteritis. Ann N Y Acad Sci 2005 1.14
56 Chronic inflammation and aging: DNA damage tips the balance. Curr Opin Immunol 2012 1.13
57 Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis. Circulation 2011 1.12
58 Molecular basis for the loss of CD28 expression in senescent T cells. J Biol Chem 2002 1.11
59 Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age. Proc Natl Acad Sci U S A 2012 1.11
60 CD8+CD45RA+CCR7+FOXP3+ T cells with immunosuppressive properties: a novel subset of inducible human regulatory T cells. J Immunol 2012 1.10
61 T cells in arteritis and atherosclerosis. Curr Opin Lipidol 2008 1.10
62 Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors. Blood 2006 1.09
63 TLR-mediated induction of negative regulatory ligands on dendritic cells. J Mol Med (Berl) 2008 1.09
64 Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age. Proc Natl Acad Sci U S A 2012 1.08
65 T cell costimulation by fractalkine-expressing synoviocytes in rheumatoid arthritis. Arthritis Rheum 2005 1.08
66 Lymphotoxin beta-mediated stimulation of synoviocytes in rheumatoid arthritis. Arthritis Rheum 2004 1.08
67 Distinct transcriptional control mechanisms of killer immunoglobulin-like receptors in natural killer (NK) and in T cells. J Biol Chem 2005 1.07
68 ERK-dependent T cell receptor threshold calibration in rheumatoid arthritis. J Immunol 2009 1.06
69 Cell-based immunotherapy with suppressor CD8+ T cells in rheumatoid arthritis. J Immunol 2005 1.05
70 T-cell aging in rheumatoid arthritis. Curr Opin Rheumatol 2014 1.04
71 Toll-like receptors in giant cell arteritis. Clin Immunol 2005 1.04
72 Association of HLA-C3 and smoking with vasculitis in patients with rheumatoid arthritis. Arthritis Rheum 2006 1.01
73 Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis. Am J Pathol 2004 1.01
74 Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells. J Leukoc Biol 2008 1.00
75 IL-7- and IL-15-mediated TCR sensitization enables T cell responses to self-antigens. J Immunol 2013 0.99
76 Tissue trafficking patterns of effector memory CD4+ T cells in rheumatoid arthritis. Arthritis Rheum 2005 0.99
77 T-cell-targeted therapies in rheumatoid arthritis. Nat Clin Pract Rheumatol 2006 0.98
78 Stem cell aging and autoimmunity in rheumatoid arthritis. Trends Mol Med 2004 0.98
79 B cells in rheumatoid synovitis. Arthritis Res Ther 2005 0.98
80 Fractalkine mediates T cell-dependent proliferation of synovial fibroblasts in rheumatoid arthritis. Arthritis Rheum 2007 0.97
81 Synoviocyte-mediated expansion of inflammatory T cells in rheumatoid synovitis is dependent on CD47-thrombospondin 1 interaction. J Immunol 2003 0.97
82 The double life of NK receptors: stimulation or co-stimulation? Trends Immunol 2004 0.97
83 Giant cell arteritis: immune and vascular aging as disease risk factors. Arthritis Res Ther 2011 0.95
84 Vascular damage in giant cell arteritis. Autoimmunity 2009 0.95
85 Synoviocyte stimulation by the LFA-1-intercellular adhesion molecule-2-Ezrin-Akt pathway in rheumatoid arthritis. J Immunol 2008 0.94
86 Mechanisms of immunosenescence: lessons from models of accelerated immune aging. Ann N Y Acad Sci 2012 0.93
87 Macrophages in vascular inflammation--From atherosclerosis to vasculitis. Autoimmunity 2015 0.91
88 Lymphoma in rheumatoid arthritis: an immune system set up for failure. Arthritis Rheum 2006 0.89
89 Age-dependent signature of metallothionein expression in primary CD4 T cell responses is due to sustained zinc signaling. Rejuvenation Res 2008 0.89
90 Reactive nitrogen intermediates in giant cell arteritis: selective nitration of neocapillaries. Am J Pathol 2002 0.88
91 Finding Balance: T cell Regulatory Receptor Expression during Aging. Aging Dis 2011 0.86
92 Magnetic resonance angiography in extracranial giant cell arteritis. J Clin Rheumatol 2011 0.85
93 K-RAS GTPase- and B-RAF kinase-mediated T-cell tolerance defects in rheumatoid arthritis. Proc Natl Acad Sci U S A 2012 0.85
94 Tumor necrosis factor-alpha and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription. J Biol Chem 2004 0.85
95 Insufficient deactivation of the protein tyrosine kinase lck amplifies T-cell responsiveness in acute coronary syndrome. Circ Res 2009 0.84
96 A population biological approach to understanding the maintenance and loss of the T-cell repertoire during aging. Immunology 2014 0.83
97 Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages. Blood 2010 0.81
98 Autophagy in autoimmune disease. J Mol Med (Berl) 2015 0.81
99 Premature immunosenescence in rheumatoid arthritis. J Rheumatol 2002 0.81
100 Dampened ERK signaling in hematopoietic progenitor cells in rheumatoid arthritis. Clin Immunol 2012 0.80
101 Pathogenic mechanisms in giant cell arteritis. Cleve Clin J Med 2002 0.80
102 Immune senescence. Curr Opin Immunol 2010 0.79
103 Immunosuppression in atherosclerosis: mobilizing the opposition within. Circulation 2006 0.79
104 B cells as a therapeutic target in autoimmune diseases. Expert Opin Ther Targets 2005 0.78
105 Immune activation caused by vascular oxidation promotes fibrosis and hypertension. J Clin Invest 2016 0.77
106 Pathomechanisms in rheumatoid arthritis--time for a string theory? J Clin Invest 2006 0.77
107 Biology of T lymphocytes. Rheum Dis Clin North Am 2004 0.76
108 Treatment of chronic inflammatory diseases with biologic agents: opportunities and risks for the elderly. Exp Gerontol 2006 0.75
109 HLA-DRB1 haplotype did not affect the medium-term results of total knee arthroplasty in patients with rheumatoid arthritis. Mod Rheumatol 2004 0.75
110 Lipopolysaccharide, CD14 and Toll-like receptors: an emerging link between innate immunity and atherosclerotic disease. Future Cardiol 2005 0.75
111 Bi-directional modulation of T cell-dependent antibody production by prostaglandin E(2). Int Immunol 2002 0.75