Macrophages in vascular inflammation--From atherosclerosis to vasculitis.

PubWeight™: 0.91‹?›

🔗 View Article (PMC 4606880)

Published in Autoimmunity on March 26, 2015

Authors

Tsuyoshi Shirai1, Marc Hilhorst, David G Harrison, Jörg J Goronzy, Cornelia M Weyand

Author Affiliations

1: Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine , Stanford, CA , USA and.

Articles citing this

The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease. J Exp Med (2016) 0.90

Clinical and pathological evolution of giant cell arteritis: a prospective study of follow-up temporal artery biopsies in 40 treated patients. Mod Pathol (2017) 0.83

Development and Function of Arterial and Cardiac Macrophages. Trends Immunol (2016) 0.81

Perivascular adipose tissue inflammation in vascular disease. Br J Pharmacol (2017) 0.79

Novel Immune Mechanisms in Hypertension and Cardiovascular Risk. Curr Cardiovasc Risk Rep (2017) 0.77

Giant Cell Arteritis: From Pathogenesis to Therapeutic Management. Curr Treatm Opt Rheumatol (2016) 0.77

Association of polymorphisms in the MAFB gene and the risk of coronary artery disease and ischemic stroke: a case-control study. Lipids Health Dis (2015) 0.76

Inflammatory Adipokines Decrease Expression of Two High Molecular Weight Isoforms of Tropomyosin Similar to the Change in Type 2 Diabetic Patients. PLoS One (2016) 0.75

Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using (111)In-tilmanocept. EJNMMI Res (2017) 0.75

Toll-like receptor 4 mutation suppresses hyperhomocysteinemia-induced hypertension. Am J Physiol Cell Physiol (2016) 0.75

Accelerated atherosclerosis in patients with chronic inflammatory rheumatologic conditions. Int J Clin Rheumtol (2015) 0.75

Sodium and Its Role in Cardiovascular Disease - The Debate Continues. Front Endocrinol (Lausanne) (2016) 0.75

Toll-like receptor 4 mediates vascular remodeling in hyperhomocysteinemia. Mol Cell Biochem (2017) 0.75

Metabolic signatures of T-cells and macrophages in rheumatoid arthritis. Curr Opin Immunol (2017) 0.75

Articles cited by this

(truncated to the top 100)

Exploring the full spectrum of macrophage activation. Nat Rev Immunol (2008) 26.08

The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol (2004) 19.38

Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol (2007) 17.18

Macrophage plasticity and polarization: in vivo veritas. J Clin Invest (2012) 13.44

Development of monocytes, macrophages, and dendritic cells. Science (2010) 12.86

Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature (2007) 11.59

Macrophage activation and polarization. Front Biosci (2008) 11.17

Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J Clin Invest (2007) 9.09

Macrophage biology in development, homeostasis and disease. Nature (2013) 8.28

Macrophages in the pathogenesis of atherosclerosis. Cell (2011) 7.78

The immune system in atherosclerosis. Nat Immunol (2011) 6.51

Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest (2007) 6.31

Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance. Cell Metab (2008) 5.83

Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metab (2008) 5.53

Immune and inflammatory mechanisms of atherosclerosis (*). Annu Rev Immunol (2009) 5.28

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses. Nat Immunol (2011) 5.11

Kawasaki syndrome. Lancet (2004) 5.09

Atherosclerosis: current pathogenesis and therapeutic options. Nat Med (2011) 4.95

Pattern recognition receptors: doubling up for the innate immune response. Cell (2002) 4.84

Myocardial infarction accelerates atherosclerosis. Nature (2012) 4.48

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis. J Clin Invest (2011) 4.21

MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature (1999) 4.19

Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency. Arterioscler Thromb Vasc Biol (2005) 4.09

Medium- and large-vessel vasculitis. N Engl J Med (2003) 3.96

Therapeutic siRNA silencing in inflammatory monocytes in mice. Nat Biotechnol (2011) 3.95

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS). Am Heart J (2011) 3.93

In vivo 18F-fluorodeoxyglucose positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients. J Am Coll Cardiol (2006) 3.91

Macrophages in atherosclerosis: a dynamic balance. Nat Rev Immunol (2013) 3.85

Metabolism of inflammation limited by AMPK and pseudo-starvation. Nature (2013) 3.76

Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice. Circulation (2008) 3.69

Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent. J Exp Med (2006) 3.65

Accumulation of ultrasmall superparamagnetic particles of iron oxide in human atherosclerotic plaques can be detected by in vivo magnetic resonance imaging. Circulation (2003) 3.58

Clinical practice. Giant-cell arteritis and polymyalgia rheumatica. N Engl J Med (2014) 3.46

Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture. Physiol Rev (2005) 3.30

Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress. Cell Metab (2010) 3.29

Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis. Nat Med (2006) 3.15

Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis. Proc Natl Acad Sci U S A (2003) 3.10

Krüppel-like factor 4 regulates macrophage polarization. J Clin Invest (2011) 3.08

Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice. Circ Res (2001) 3.07

Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice. Proc Natl Acad Sci U S A (2006) 3.00

The macrophage foam cell as a target for therapeutic intervention. Nat Med (2002) 2.98

Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions. Circulation (2008) 2.98

Enhancer-mediated control of macrophage-specific arginase I expression. J Immunol (2004) 2.95

Mouse models of abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol (2004) 2.94

Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circ Res (2011) 2.89

Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis? Circulation (2002) 2.80

Macrophage diversity and polarization in atherosclerosis: a question of balance. Arterioscler Thromb Vasc Biol (2009) 2.80

Macrophage plasticity in experimental atherosclerosis. PLoS One (2010) 2.75

Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J Exp Med (2012) 2.69

Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice. Circulation (2010) 2.69

M1 and M2 Macrophages: Oracles of Health and Disease. Crit Rev Immunol (2012) 2.49

A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. Nature (1997) 2.44

Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. Am J Pathol (2005) 2.38

The role of the adventitia in vascular inflammation. Cardiovasc Res (2007) 2.21

The immunopathology of giant cell arteritis: diagnostic and therapeutic implications. J Neuroophthalmol (2012) 2.19

Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis. J Am Soc Nephrol (2010) 2.03

Pathogenesis of antineutrophil cytoplasmic autoantibody-associated small-vessel vasculitis. Annu Rev Pathol (2013) 2.02

Recent advances on the role of cytokines in atherosclerosis. Arterioscler Thromb Vasc Biol (2011) 1.98

Innate immunity, macrophage activation, and atherosclerosis. Immunol Rev (2007) 1.94

Vessel-specific Toll-like receptor profiles in human medium and large arteries. Circulation (2008) 1.91

Molecular mediators of macrophage fusion. Trends Cell Biol (2009) 1.91

Phagocytosis in atherosclerosis: Molecular mechanisms and implications for plaque progression and stability. Cardiovasc Res (2006) 1.87

Heterogeneity of human macrophages in culture and in atherosclerotic plaques. Am J Pathol (2008) 1.86

Free cholesterol loading of macrophages induces apoptosis involving the fas pathway. J Biol Chem (2000) 1.85

Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function. J Leukoc Biol (2011) 1.82

Distribution of macrophage polarization markers in human atherosclerosis. Atherosclerosis (2012) 1.79

MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. J Clin Invest (2012) 1.77

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1. J Exp Med (2013) 1.73

The impact of the inflammatory response on coagulation. Thromb Res (2004) 1.73

Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis. J Exp Med (2004) 1.70

Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial. Lancet (2008) 1.69

Neutrophil priming and apoptosis in anti-neutrophil cytoplasmic autoantibody-associated vasculitis. Kidney Int (2001) 1.67

Phagocytosis of apoptotic cells and the resolution of inflammation. Biochim Biophys Acta (2003) 1.60

Role of Kruppel-like factors in leukocyte development, function, and disease. Blood (2010) 1.54

Chronic inflammation: a failure of resolution? Int J Exp Pathol (2007) 1.54

Correlation of the topographical arrangement and the functional pattern of tissue-infiltrating macrophages in giant cell arteritis. J Clin Invest (1996) 1.54

Sphingosine-1-phosphate receptor 3 promotes recruitment of monocyte/macrophages in inflammation and atherosclerosis. Circ Res (2010) 1.50

Apoptosis and efferocytosis in mouse models of atherosclerosis. Curr Drug Targets (2007) 1.50

Pathogenesis of Takayasu's arteritis: a 2011 update. Autoimmun Rev (2011) 1.49

Coronary vasa vasorum neovascularization precedes epicardial endothelial dysfunction in experimental hypercholesterolemia. Cardiovasc Res (2001) 1.49

Immune mechanisms in medium and large-vessel vasculitis. Nat Rev Rheumatol (2013) 1.48

Interferon-gamma-producing T cells in giant cell vasculitis represent a minority of tissue-infiltrating cells and are located distant from the site of pathology. Am J Pathol (1996) 1.43

Prolonged infusion of angiotensin II in apoE(-/-) mice promotes macrophage recruitment with continued expansion of abdominal aortic aneurysm. Am J Pathol (2011) 1.43

Formation of new vasa vasorum in vasculitis. Production of angiogenic cytokines by multinucleated giant cells. Am J Pathol (1999) 1.41

The myeloid transcription factor KLF2 regulates the host response to polymicrobial infection and endotoxic shock. Immunity (2011) 1.39

Macrophage apoptosis in atherosclerosis: consequences on plaque progression and the role of endoplasmic reticulum stress. Antioxid Redox Signal (2009) 1.34

The adventitia: essential regulator of vascular wall structure and function. Annu Rev Physiol (2012) 1.31

Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis. J Clin Invest (1999) 1.30

CC chemokine receptor 2 is required for macrophage infiltration and vascular hypertrophy in angiotensin II-induced hypertension. Hypertension (2000) 1.27

Inhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation. J Immunol (2009) 1.26

Mechanisms of T cell-induced glomerular injury in anti-glomerular basement membrane (GBM) glomerulonephritis in rats. Clin Exp Immunol (1997) 1.25

Tissue-destructive macrophages in giant cell arteritis. Circ Res (1999) 1.23

Platelet-derived growth factor, intimal hyperplasia, and ischemic complications in giant cell arteritis. Arthritis Rheum (1998) 1.19

Pathophysiology of atherosclerosis plaque progression. Heart Lung Circ (2013) 1.19

Pathogenesis of Kawasaki disease. Clin Exp Immunol (2011) 1.18

TNF-alpha and IL-4 synergistically increase vascular cell adhesion molecule-1 expression in cultured vascular smooth muscle cells. J Immunol (1997) 1.13

The influence of innate and adaptive immune responses on atherosclerosis. Annu Rev Pathol (2013) 1.13

Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis. Circulation (2011) 1.12

Mammalian stanniocalcin-1 activates mitochondrial antioxidant pathways: new paradigms for regulation of macrophages and endothelium. Am J Physiol Renal Physiol (2009) 1.12

Apoptosis of vascular smooth muscle cells is induced by Fas ligand derived from monocytes/macrophage. Atherosclerosis (2002) 1.12

Articles by these authors

Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction. J Exp Med (2007) 7.69

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest (2003) 6.30

Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction. Circ Res (2007) 4.48

The influence of age on T cell generation and TCR diversity. J Immunol (2005) 4.36

Medium- and large-vessel vasculitis. N Engl J Med (2003) 3.96

Infliximab for maintenance of glucocorticosteroid-induced remission of giant cell arteritis: a randomized trial. Ann Intern Med (2007) 3.81

Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids: a double-blind, placebo-controlled, randomized prospective clinical trial. Arthritis Rheum (2006) 3.64

Giant-cell arteritis and polymyalgia rheumatica. Ann Intern Med (2003) 3.48

Clinical practice. Giant-cell arteritis and polymyalgia rheumatica. N Engl J Med (2014) 3.46

Inflammation, immunity, and hypertension. Hypertension (2010) 3.43

Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase. J Biol Chem (2003) 3.23

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II. Hypertension (2002) 3.23

Measurement of reactive oxygen species in cardiovascular studies. Hypertension (2007) 3.17

Therapeutic targeting of mitochondrial superoxide in hypertension. Circ Res (2010) 3.16

The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol Sci (2003) 3.13

Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction. Hypertension (2009) 3.06

HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group. J Acquir Immune Defic Syndr (2012) 2.95

Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction. Circulation (2010) 2.95

Detection of intracellular superoxide formation in endothelial cells and intact tissues using dihydroethidium and an HPLC-based assay. Am J Physiol Cell Physiol (2004) 2.94

Role of extracellular superoxide dismutase in hypertension. Hypertension (2006) 2.74

Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production. Free Radic Biol Med (2008) 2.68

ATVB in focus: redox mechanisms in blood vessels. Arterioscler Thromb Vasc Biol (2004) 2.45

Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease. J Am Coll Cardiol (2008) 2.44

Inflammatory markers and incident heart failure risk in older adults: the Health ABC (Health, Aging, and Body Composition) study. J Am Coll Cardiol (2010) 2.43

T cell subset-specific susceptibility to aging. Clin Immunol (2008) 2.42

T cell development and receptor diversity during aging. Curr Opin Immunol (2005) 2.29

Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension. Circ Res (2010) 2.28

Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice. Arterioscler Thromb Vasc Biol (2011) 2.27

Downregulation of endocardial nitric oxide synthase expression and nitric oxide production in atrial fibrillation: potential mechanisms for atrial thrombosis and stroke. Circulation (2002) 2.22

The immunopathology of giant cell arteritis: diagnostic and therapeutic implications. J Neuroophthalmol (2012) 2.19

Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity. Nat Med (2012) 2.19

Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress. Am J Physiol Heart Circ Physiol (2003) 2.09

Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion. J Biol Chem (2003) 2.09

Understanding immunosenescence to improve responses to vaccines. Nat Immunol (2013) 2.09

Prognostic markers of radiographic progression in early rheumatoid arthritis. Arthritis Rheum (2004) 2.08

Established and emerging plasma biomarkers in the prediction of first atherothrombotic events. Circulation (2004) 2.07

Aging and T-cell diversity. Exp Gerontol (2007) 2.06

Atrial fibrillation increases production of superoxide by the left atrium and left atrial appendage: role of the NADPH and xanthine oxidases. Circulation (2005) 2.02

Association between novel oxidative stress markers and C-reactive protein among adults without clinical coronary heart disease. Atherosclerosis (2005) 2.02

Regulation of tetrahydrobiopterin biosynthesis by shear stress. Circ Res (2007) 2.01

Regulation of T-cell function by endogenously produced angiotensin II. Am J Physiol Regul Integr Comp Physiol (2008) 1.98

Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells. J Exp Med (2013) 1.96

Rheumatoid arthritis. Immunol Rev (2005) 1.94

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. J Clin Invest (2013) 1.92

Vessel-specific Toll-like receptor profiles in human medium and large arteries. Circulation (2008) 1.91

Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation. J Clin Invest (2015) 1.89

Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes. Circ Res (2009) 1.88

Th17 and Th1 T-cell responses in giant cell arteritis. Circulation (2010) 1.88

Modulation of CD28 expression with anti-tumor necrosis factor alpha therapy in rheumatoid arthritis. Arthritis Rheum (2005) 1.88

Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase. Circulation (2002) 1.87

Induction of hypertension and peripheral inflammation by reduction of extracellular superoxide dismutase in the central nervous system. Hypertension (2009) 1.86

Peroxidase properties of extracellular superoxide dismutase: role of uric acid in modulating in vivo activity. Arterioscler Thromb Vasc Biol (2002) 1.81

Therapeutic effects of acetylsalicylic acid in giant cell arteritis. Arthritis Rheum (2002) 1.80

Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha. Circulation (2006) 1.77

Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque. Circ Res (2006) 1.77

BLyS and APRIL in rheumatoid arthritis. J Clin Invest (2005) 1.75

Regulation of T cell receptor signaling by activation-induced zinc influx. J Exp Med (2011) 1.73

The AT(1)-type angiotensin receptor in oxidative stress and atherogenesis: part I: oxidative stress and atherogenesis. Circulation (2002) 1.72

Coronary artery superoxide production and nox isoform expression in human coronary artery disease. Arterioscler Thromb Vasc Biol (2005) 1.72

T-cell-mediated lysis of endothelial cells in acute coronary syndromes. Circulation (2002) 1.72

Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis. J Exp Med (2004) 1.70

Extracellular superoxide dismutase and cardiovascular disease. Cardiovasc Res (2002) 1.68

Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension. Circulation (2010) 1.68

Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: implications for uncoupling endothelial nitric oxide synthase. Biochem Pharmacol (2005) 1.66

Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages. Proc Natl Acad Sci U S A (2003) 1.65

T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome. Circ Res (2006) 1.62

Epigenetic regulation of killer immunoglobulin-like receptor expression in T cells. Blood (2009) 1.62

Homeostatic control of T-cell generation in neonates. Blood (2003) 1.62

Aging, autoimmunity and arthritis: T-cell senescence and contraction of T-cell repertoire diversity - catalysts of autoimmunity and chronic inflammation. Arthritis Res Ther (2003) 1.61

Vascular NADPH oxidases as drug targets for novel antioxidant strategies. Drug Discov Today (2006) 1.59

DC isoketal-modified proteins activate T cells and promote hypertension. J Clin Invest (2014) 1.59

The relationship between plasma levels of oxidized and reduced thiols and early atherosclerosis in healthy adults. J Am Coll Cardiol (2006) 1.59

Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes. Am J Physiol Heart Circ Physiol (2007) 1.57

Immune activation caused by vascular oxidation promotes fibrosis and hypertension. J Clin Invest (2015) 1.55

Telomerase insufficiency in rheumatoid arthritis. Proc Natl Acad Sci U S A (2009) 1.54

Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis. J Exp Med (2009) 1.54

Requirement of argininosuccinate lyase for systemic nitric oxide production. Nat Med (2011) 1.54