Published in J Nat Prod on September 01, 2002
Bioactive 5,6-dihydro-alpha-pyrone derivatives from Hyptis brevipes. J Nat Prod (2009) 1.48
Potential anticancer activity of naturally occurring and semisynthetic derivatives of aculeatins A and B from Amomum aculeatum. J Nat Prod (2008) 1.12
Laurenditerpenol, a new diterpene from the tropical marine alga Laurenciaintricata that potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells. J Nat Prod (2004) 1.11
Smardaesidins A-G, isopimarane and 20-nor-isopimarane diterpenoids from Smardaea sp., a fungal endophyte of the moss Ceratodon purpureus. J Nat Prod (2011) 0.98
Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen). J Nat Prod (2009) 0.97
Isolation, structure elucidation, and biological evaluation of 16,23-epoxycucurbitacin constituents from Eleaocarpus chinensis. J Nat Prod (2012) 0.93
Antimalarial 5,6-Dihydro-α-pyrones from Cryptocarya rigidifolia: Related Bicyclic Tetrahydro-α-Pyrones Are Artifacts1. J Nat Prod (2015) 0.93
Bioactive flavaglines and other constituents isolated from Aglaia perviridis. J Nat Prod (2013) 0.90
Dioxadispiroketal Compounds and a Potential Acyclic Precursor from Amomum aculeatum. Tetrahedron Lett (2007) 0.87
Cytotoxic constituents from the fruiting branches of Callicarpa americana collected in southern Florida. J Nat Prod (2007) 0.86
Antiproliferative acetogenins from a Uvaria sp. from the Madagascar dry forest. J Nat Prod (2011) 0.85
Pierreiones A-D, solid tumor selective pyranoisoflavones and other cytotoxic constituents from Antheroporum pierrei. J Nat Prod (2011) 0.83
Isolation of pyrrolocins A-C: cis- and trans-decalin tetramic acid antibiotics from an endophytic fungal-derived pathway. J Nat Prod (2014) 0.83
Tricinonoic acid and tricindiol, two new irregular sesquiterpenes from an endophytic strain of Fusarium tricinctum. Nat Prod Res (2010) 0.82
Structures and potential antitumor activity of sesterterpenes from the marine sponge Hyrtios communis. J Nat Prod (2013) 0.81
Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities. J Nat Prod (2013) 0.80
Biosynthetic products from a nearshore-derived gram-negative bacterium enable reassessment of the kailuin depsipeptides. J Nat Prod (2015) 0.78
Oxaspirol B with p97 Inhibitory Activity and Other Oxaspirols from Lecythophora sp. FL1375 and FL1031, Endolichenic Fungi Inhabiting Parmotrema tinctorum and Cladonia evansii. J Nat Prod (2016) 0.77
Antileukemic α-pyrone derivatives from the endophytic fungus Alternaria phragmospora. Tetrahedron Lett (2014) 0.75
An epigenetic modifier induces production of (10'S)-verruculide B, an inhibitor of protein tyrosine phosphatases by Phoma sp. nov. LG0217, a fungal endophyte of Parkinsonia microphylla. Bioorg Med Chem (2017) 0.75
Cyclopenta[b]benzofuran and Secodammarane Derivatives from the Stems of Aglaia stellatopilosa. J Nat Prod (2016) 0.75
Penicimenolides A-F, Resorcylic Acid Lactones from Penicillium sp., isolated from the Rhizosphere Soil of Panax notoginseng. Sci Rep (2016) 0.75
BIOLOGICALLY ACTIVE NATURAL PRODUCTS OF THE GENUS CALLICARPA. Curr Bioact Compd (2008) 0.75
Antileishmanial metabolites from Geosmithia langdonii. J Nat Prod (2014) 0.75
New acyclic bis phenylpropanoid and neolignans, from Myristica fragrans Houtt., exhibiting PARP-1 and NF-κB inhibitory effects. Food Chem (2016) 0.75
Drug discovery from medicinal plants. Life Sci (2005) 4.26
Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis. Biochemistry (2005) 3.57
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proc Natl Acad Sci U S A (2005) 2.92
Drug discovery from natural sources. AAPS J (2006) 2.76
High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors. PLoS Pathog (2009) 2.76
The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity. J Virol (2005) 2.49
Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity. Cancer Res (2005) 2.49
Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells. J Natl Cancer Inst (2003) 2.31
Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme. Proc Natl Acad Sci U S A (2006) 2.28
Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis. J Natl Cancer Inst (2005) 2.09
Botanicals in cancer chemoprevention. Cancer Metastasis Rev (2002) 2.09
Cancer prevention with natural compounds. Semin Oncol (2010) 1.98
Body mass index and cancer risk in Korean men and women. Int J Cancer (2008) 1.89
Cancer chemopreventive activity of resveratrol. Ann N Y Acad Sci (2002) 1.88
Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. Nat Genet (2012) 1.85
The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo. Blood (2009) 1.83
New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge. J Nat Prod (2003) 1.81
Potential of cyclopenta[b]benzofurans from Aglaia species in cancer chemotherapy. Anticancer Agents Med Chem (2006) 1.76
What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. PLoS One (2011) 1.74
Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. J Org Chem (2004) 1.69
Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases. J Virol (2010) 1.64
Antifungal activity of some Tanzanian plants used traditionally for the treatment of fungal infections. J Ethnopharmacol (2006) 1.64
Human, rat, and mouse metabolism of resveratrol. Pharm Res (2002) 1.62
Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling. J Virol (2009) 1.58
Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor. J Agric Food Chem (2003) 1.56
Screening of Tanzanian medicinal plants for anti-Candida activity. BMC Complement Altern Med (2006) 1.55
Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia. J Immunol (2003) 1.54
Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen). J Agric Food Chem (2006) 1.54
Identification of the highly reactive cysteine 151 in the chemopreventive agent-sensor Keap1 protein is method-dependent. Chem Res Toxicol (2007) 1.53
Anti-tumorigenicity of dietary α-mangostin in an HT-29 colon cell xenograft model and the tissue distribution of xanthones and their phase II metabolites. Mol Nutr Food Res (2012) 1.48
Bioactive 5,6-dihydro-alpha-pyrone derivatives from Hyptis brevipes. J Nat Prod (2009) 1.48
NFkappaB: a promising target for natural products in cancer chemoprevention. Phytother Res (2010) 1.45
Natural inhibitors of carcinogenesis. Planta Med (2004) 1.43
Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites. J Med Chem (2010) 1.41
A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A (2008) 1.39
Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests. J Nat Prod (2002) 1.39
Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63. J Virol (2007) 1.39
Sites of alkylation of human Keap1 by natural chemoprevention agents. J Am Soc Mass Spectrom (2007) 1.36
Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol. J Agric Food Chem (2002) 1.36
Molecular mechanisms of natural products in chemoprevention: induction of cytoprotective enzymes by Nrf2. Mol Nutr Food Res (2008) 1.33
Experience of initiating collaboration of traditional healers in managing HIV and AIDS in Tanzania. J Ethnobiol Ethnomed (2007) 1.32
Cytotoxic anticancer candidates from natural resources. Curr Med Chem Anticancer Agents (2002) 1.32
Silvestrol regulates G2/M checkpoint genes independent of p53 activity. Anticancer Res (2006) 1.26
Isolation, structure elucidation, and absolute configuration of 26-deoxyactein from Cimicifuga racemosa and clarification of nomenclature associated with 27-deoxyactein. J Nat Prod (2002) 1.26
Pleiotropic mechanisms facilitated by resveratrol and its metabolites. Biochem J (2010) 1.26
Plants used to treat epilepsy by Tanzanian traditional healers. J Ethnopharmacol (2005) 1.25
Suppression of transient receptor potential melastatin 7 channel induces cell death in gastric cancer. Cancer Sci (2008) 1.24
Estrogens and congeners from spent hops (Humulus lupulus). J Nat Prod (2004) 1.24
Quinone reductase induction as a biomarker for cancer chemoprevention. J Nat Prod (2006) 1.24
Silvestrol, a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7. Anticancer Res (2007) 1.23
Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis. J Nat Prod (2006) 1.23
Bioactive constituents of the stem bark of Mitrephora glabra. J Nat Prod (2009) 1.23
Isolation and characterization of minor analogues of silvestrol and other constituents from a large-scale re-collection of Aglaia foveolata. J Nat Prod (2010) 1.23
Betulinic acid-induced programmed cell death in human melanoma cells involves mitogen-activated protein kinase activation. Clin Cancer Res (2003) 1.21
Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase. Chem Res Toxicol (2005) 1.20
Resveratrol derivatives as promising chemopreventive agents with improved potency and selectivity. Mol Nutr Food Res (2011) 1.20
Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles. J Agric Food Chem (2002) 1.19
Modification of keap1 cysteine residues by sulforaphane. Chem Res Toxicol (2011) 1.17
Suppression of TNF-α induced NFκB activity by gallic acid and its semi-synthetic esters: possible role in cancer chemoprevention. Nat Prod Res (2010) 1.17
Bioactive constituents from roots of Bursera tonkinensis. Phytochemistry (2005) 1.17
Hapalindole-related alkaloids from the cultured cyanobacterium Fischerella ambigua. Phytochemistry (2010) 1.17
"Studies on biodiversity of Vietnam and Laos" 1998-2005: examining the impact. J Nat Prod (2006) 1.14
Role of traditional healers in psychosocial support in caring for the orphans: a case of Dar-es Salaam City, Tanzania. J Ethnobiol Ethnomed (2005) 1.14
Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors. J Med Chem (2005) 1.13
Extract of the Chinese herbal formula Huo Luo Xiao Ling Dan inhibited adjuvant arthritis in rats. J Ethnopharmacol (2008) 1.13
Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2. Biochem J (2008) 1.13
Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway. J Immunol (2010) 1.12
Potential anticancer activity of naturally occurring and semisynthetic derivatives of aculeatins A and B from Amomum aculeatum. J Nat Prod (2008) 1.12
JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells. J Biol Chem (2002) 1.12
Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J Mol Biol (2009) 1.11
Chemical Diversity of Metabolites from Fungi, Cyanobacteria, and Plants Relative to FDA-Approved Anticancer Agents. ACS Med Chem Lett (2012) 1.11
Cancer chemopreventive activity and metabolism of isoliquiritigenin, a compound found in licorice. Cancer Prev Res (Phila) (2010) 1.11
Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells. AAPS J (2011) 1.11
Structural basis for thermostability revealed through the identification and characterization of a highly thermostable phosphotriesterase-like lactonase from Geobacillus stearothermophilus. Arch Biochem Biophys (2009) 1.10
Selective induction of apoptosis of human oral cancer cell lines by avocado extracts via a ROS-mediated mechanism. Nutr Cancer (2009) 1.10
Prospective type 1 and type 2 disulfides of Keap1 protein. Chem Res Toxicol (2008) 1.09
Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized Sprague-Dawley rats. J Nutr (2002) 1.09
Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities. J Med Chem (2009) 1.09
Activity-guided isolation of cytotoxic constituents from the bark of Aglaia crassinervia collected in Indonesia. Bioorg Med Chem (2005) 1.09