Published in Curr Med Chem Anticancer Agents on July 01, 2002
General synthesis for chiral 4-alkyl-4-hydroxycyclohexenones. Org Lett (2006) 1.14
Commentary on Traditional and Modern Biomedical Prospecting: Part II-The Benefits by Werner E.G. Muller, Heinz C. Schroder, Matthias Wiens, Sanja Perovic-Ottstadt, Renato Batel and Isabel M. Muller: Anti-protozoa and antiviral activities of non-cytotoxic truncated and variant analogues of mussel defensin by P. Roch, A. Beschin and E. Bernard. Evid Based Complement Alternat Med (2004) 1.14
The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8. Proc Natl Acad Sci U S A (2008) 1.05
Mechanism targeted discovery of antitumor marine natural products. Curr Med Chem (2004) 0.95
De novo leaf and root transcriptome analysis identified novel genes involved in steroidal sapogenin biosynthesis in Asparagus racemosus. BMC Genomics (2014) 0.92
In vitro anticancer screening of 24 locally used Nigerian medicinal plants. BMC Complement Altern Med (2013) 0.90
In vitro anti-inflammatory and pro-aggregative effects of a lipid compound, petrocortyne A, from marine sponges. Naunyn Schmiedebergs Arch Pharmacol (2003) 0.90
In vitro Cytotoxic and Antimicrobial Activity of Essential Oil From Satureja Intermedia. Iran Red Crescent Med J (2013) 0.83
2-deprenyl-rheediaxanthone B isolated from Metaxya rostrata induces active cell death in colorectal tumor cells. PLoS One (2013) 0.78
Growth Inhibition and Apoptosis with H31 Metabolites from Marine Bacillus SW31 in Head and Neck Cancer Cells. Clin Exp Otorhinolaryngol (2010) 0.77
In vitro anti-proliferative activity of Argemone gracilenta and identification of some active components. BMC Complement Altern Med (2015) 0.76
Shatavarins (containing Shatavarin IV) with anticancer activity from the roots of Asparagus racemosus. Indian J Pharmacol (2012) 0.75
Verbesina encelioides: cytotoxicity, cell cycle arrest, and oxidative DNA damage in human liver cancer (HepG2) cell line. BMC Complement Altern Med (2016) 0.75
Two Unusual Methylidenecyclopropane Glucosides from Metaxya rostrata C.Presl. Helv Chim Acta (2012) 0.75
Molecular interaction studies of amorphous solid dispersions of the antimelanoma agent betulinic acid. AAPS PharmSciTech (2014) 0.75
In Vitro Antibacterial, Antifungal, Antibiofilm, Antioxidant, and Anticancer Properties of Isosteviol Isolated from Endangered Medicinal Plant Pittosporum tetraspermum. Evid Based Complement Alternat Med (2015) 0.75
Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer Cells. Curr Genomics (2017) 0.75
Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells. Drug Des Devel Ther (2017) 0.75
High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors. PLoS Pathog (2009) 2.76
Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity. Cancer Res (2005) 2.49
Body mass index and cancer risk in Korean men and women. Int J Cancer (2008) 1.89
Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. Nat Genet (2012) 1.85
New chemical constituents of Euphorbia quinquecostata and absolute configuration assignment by a convenient Mosher ester procedure carried out in NMR tubes. J Nat Prod (2002) 1.74
Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia. J Immunol (2003) 1.54
Natural inhibitors of carcinogenesis. Planta Med (2004) 1.43
Suppression of transient receptor potential melastatin 7 channel induces cell death in gastric cancer. Cancer Sci (2008) 1.24
Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway. J Immunol (2010) 1.12
JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells. J Biol Chem (2002) 1.12
Gangliosides trigger inflammatory responses via TLR4 in brain glia. Am J Pathol (2006) 1.08
Wnt/β-catenin signaling mediates the antitumor activity of magnolol in colorectal cancer cells. Mol Pharmacol (2012) 1.07
Ubiquitination and degradation of the FADD adaptor protein regulate death receptor-mediated apoptosis and necroptosis. Nat Commun (2012) 1.06
Cytotoxic withanolides from Acnistus arborescens. Phytochemistry (2002) 1.05
Successful treatment of digital ulcers in a scleroderma patient with continuous bilateral thoracic sympathetic block. Pain Physician (2008) 1.04
Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians. Int J Cancer (2014) 1.03
TGF-beta1 induces cardiac hypertrophic responses via PKC-dependent ATF-2 activation. J Mol Cell Cardiol (2005) 1.03
Interleukin-13 and -4 induce death of activated microglia. Glia (2002) 1.02
Prediction of Colorectal Cancer Risk Using a Genetic Risk Score: The Korean Cancer Prevention Study-II (KCPS-II). Genomics Inform (2012) 0.99
Bioactive constituents of the seeds of Brucea javanica. Planta Med (2002) 0.97
Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels. J Biol Chem (2012) 0.97
Sulfatide, a major lipid component of myelin sheath, activates inflammatory responses as an endogenous stimulator in brain-resident immune cells. J Immunol (2008) 0.96
Clinical application of human adipose tissue-derived mesenchymal stem cells in progressive hemifacial atrophy (Parry-Romberg disease) with microfat grafting techniques using 3-dimensional computed tomography and 3-dimensional camera. Ann Plast Surg (2012) 0.95
Double-stranded RNA-activated protein kinase is required for the LPS-induced activation of STAT1 inflammatory signaling in rat brain glial cells. Glia (2005) 0.95
Endoplasmic reticulum stress mediates withaferin A-induced apoptosis in human renal carcinoma cells. Toxicol In Vitro (2011) 0.93
A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. Hum Mol Genet (2013) 0.91
Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (tonka bean). J Nat Prod (2003) 0.90
Regulation of TLR2 expression by prostaglandins in brain glia. J Immunol (2008) 0.90
Serum adiponectin is associated with smoking status in healthy Korean men. Endocr J (2008) 0.89
Potential cncer chemopreventive flavonoids from the stems of Tephrosia toxicaria. J Nat Prod (2003) 0.89
Assessing the Prevalence of Recurrent Neck and Shoulder Pain in Korean High School Male Students: A Cross-sectional Observational Study. Korean J Pain (2012) 0.89
Ethyl pyruvate induces heme oxygenase-1 through p38 mitogen-activated protein kinase activation by depletion of glutathione in RAW 264.7 cells and improves survival in septic animals. Antioxid Redox Signal (2012) 0.88
Sesquiterpenoids from Tithonia diversifolia with potential cancer chemopreventive activity. J Nat Prod (2002) 0.87
Serum adiponectin is associated with family history of diabetes independently of obesity and insulin resistance in healthy Korean men and women. Eur J Endocrinol (2009) 0.87
Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism. Chem Biol Interact (2012) 0.86
Ethanol extract of Prunella vulgaris var. lilacina inhibits HMGB1 release by induction of heme oxygenase-1 in LPS-activated RAW 264.7 cells and CLP-induced septic mice. Phytother Res (2011) 0.86
Characteristics of gintonin-mediated membrane depolarization of pacemaker activity in cultured interstitial cells of Cajal. Cell Physiol Biochem (2014) 0.86
Induction of microglial apoptosis by corticotropin-releasing hormone. J Neurochem (2006) 0.86
Flavonoids of Inula britannica protect cultured cortical cells from necrotic cell death induced by glutamate. Free Radic Biol Med (2002) 0.86
Contribution of TLR2 to the initiation of ganglioside-triggered inflammatory signaling. Mol Cells (2008) 0.86
Shoe collar height effect on athletic performance, ankle joint kinematics and kinetics during unanticipated maximum-effort side-cutting performance. J Sports Sci (2015) 0.85
Dual functionality of myeloperoxidase in rotenone-exposed brain-resident immune cells. Am J Pathol (2011) 0.85
Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation. Chem Biol Interact (2011) 0.85
Negative Pressure Wound Therapy on Closed Surgical Wounds With Dead Space: Animal Study Using a Swine Model. Ann Plast Surg (2016) 0.84
Employing mated females as recipients for transfer of cloned dog embryos. Reprod Fertil Dev (2013) 0.84
Twist2 regulates CD7 expression and galectin-1-induced apoptosis in mature T-cells. Mol Cells (2009) 0.84
RU486, a glucocorticoid receptor antagonist, induces apoptosis in U937 human lymphoma cells through reduction in mitochondrial membrane potential and activation of p38 MAPK. Oncol Rep (2013) 0.83
Activity-guided isolation of constituents of Renealmia nicolaioides with the potential to induce the phase II enzyme quinone reductase. J Nat Prod (2002) 0.83
Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity. J Org Chem (2003) 0.83
Inflexin attenuates proinflammatory responses and nuclear factor-kappaB activation in LPS-treated microglia. Eur J Pharmacol (2010) 0.83
A novel alkalo- and thermostable phospholipase D from Streptomyces olivochromogenes. Biotechnol Lett (2008) 0.82
Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora. J Nat Prod (2003) 0.82
Behavioral analysis of cloned puppies derived from an elite drug-detection dog. Behav Genet (2013) 0.82
Constituents of the stem bark of Pongamia pinnata with the potential to induce quinone reductase. J Nat Prod (2003) 0.81
Crinamine from Crinum asiaticum var. japonicum inhibits hypoxia inducible factor-1 activity but not activity of hypoxia inducible factor-2. Biol Pharm Bull (2006) 0.81
A novel cyclin-dependent kinase inhibitor down-regulates tumor necrosis factor-alpha (TNF-alpha)-induced expression of cell adhesion molecules by inhibition of NF-kappaB activation in human pulmonary epithelial cells. Int Immunopharmacol (2010) 0.81
A tetrahydroisoquinoline alkaloid THI-28 reduces LPS-induced HMGB1 and diminishes organ injury in septic mice through p38 and PI3K/Nrf2/HO-1 signals. Int Immunopharmacol (2013) 0.80
Effects of smoking and obesity on the association between CDH13 (rs3865188) and adiponectin among Korean men: the KARE study. Obesity (Silver Spring) (2011) 0.80
Valsartan independent of AT₁ receptor inhibits tissue factor, TLR-2 and -4 expression by regulation of Egr-1 through activation of AMPK in diabetic conditions. J Cell Mol Med (2014) 0.80
Potential cancer chemopreventive agents from Arbutus unedo. Nat Prod Res (2006) 0.79
In vivo differentiation of undifferentiated human adipose tissue-derived mesenchymal stem cells in critical-sized calvarial bone defects. Ann Plast Surg (2014) 0.79
Compounds obtained from sida acuta with the potential to induce quinone reductase and to inhibit 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a mouse mammary organ culture model. Arch Pharm Res (2003) 0.79
Resveratrol confers protection against rotenone-induced neurotoxicity by modulating myeloperoxidase levels in glial cells. PLoS One (2013) 0.78
Constituents of the twigs of Hernandia ovigera that inhibit the transformation of JB6 murine epidermal cells. J Nat Prod (2002) 0.78
Effects of SLC2A9 variants on uric acid levels in a Korean population. Rheumatol Int (2012) 0.78
A self-propelled biological process: Plk1-dependent, product-activated feedforward mechanism. Cell Cycle (2011) 0.78
Adjunctive atropine versus metoclopramide: can we reduce ketamine-associated vomiting in young children? a prospective, randomized, open, controlled study. Acad Emerg Med (2012) 0.77
Perceived timeliness of referral to hospice palliative care among bereaved family members in Korea. Support Care Cancer (2015) 0.77
Production of offspring from cloned transgenic RFP female dogs and stable generational transmission of the RFP gene. Genesis (2011) 0.76
Constituents of Musa x paradisiaca cultivar with the potential to induce the phase II enzyme, quinone reductase. J Agric Food Chem (2002) 0.75
Dynamic identification of phosphopeptides using immobilized metal ion affinity chromatography enrichment, subsequent partial beta-elimination/chemical tagging and matrix-assisted laser desorption/ionization mass spectrometric analysis. Rapid Commun Mass Spectrom (2004) 0.75
(S)-1-α-naphthylmethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD712), promotes wound closure by producing VEGF through HO-1 induction in human dermal fibroblasts and mouse skin. Br J Pharmacol (2013) 0.75
Intrapancreatic ectopic splenic tissue found in a cloned miniature pig. J Vet Sci (2015) 0.75
Altered cell cycle gene expression and apoptosis in post-implantation dog parthenotes. PLoS One (2012) 0.75
Post-mortem re-cloning of a transgenic red fluorescent protein dog. J Vet Sci (2011) 0.75
Prevalence and Associated Factors of Anxiety and Depressive Symptoms Among Bereaved Family Members of Cancer Patients in Korea: A Nation-Wide Cross-Sectional Study. Medicine (Baltimore) (2016) 0.75
Effects of mineral supplements on ovulation and maturation of dog oocytes. Theriogenology (2012) 0.75
The Efficacy of Cyclic Injection of Bone Morphogenetic Protein-2 in Large-Scale Calvarial Bone Defects. J Craniofac Surg (2016) 0.75
Analysis of morphological and histologic changes in intraoral fasciocutaneous free flaps used for oropharyngeal reconstruction. Ann Plast Surg (2014) 0.75
CORRELATION OF PHOTORECEPTOR INTEGRITY WITH RETINAL VESSEL DENSITY AND CHORIOCAPILLARIS IN EYES WITH DIABETIC RETINOPATHY. Retina (2022) 0.75
Effect of hole injection layer/hole transport layer polymer and device structure on the properties of white OLED. J Nanosci Nanotechnol (2008) 0.75
Phenolic compounds obtained from stems of Couepia ulei with the potential to induce quinone reductase. Arch Pharm Res (2004) 0.75
Duration of gestation in pregnant dogs carrying cloned fetuses. Theriogenology (2012) 0.75
Appropriate and Effective Dosage of BMP-2 for the Ideal Regeneration of Calvarial Bone Defects in Beagles. Plast Reconstr Surg (2016) 0.75
A glucose-inducible gene in Schizosaccharomyces pombe, rrg1+, is involved in negative regulation of G2/M progression. Mol Cells (2002) 0.75
Distinctive responses of brain tumor cells to TLR2 ligands. Glia (2015) 0.75
Does ondansetron have an effect on intramuscular ketamine-associated vomiting in children? A prospective, randomised, open, controlled study. J Paediatr Child Health (2014) 0.75
Comparison of Biomechanical and Histological Outcomes of Different Suture Techniques in Rat Rectus Abdominis Muscle Repair. Ann Plast Surg (2017) 0.75
Analysis of cell growth and gene expression of porcine adipose tissue-derived mesenchymal stem cells as nuclear donor cell. Dev Growth Differ (2014) 0.75
Three-vessel view of the fetal heart: in utero development of the great vessels. Prenat Diagn (2007) 0.75